Selective killing of cancer cells by β-lapachone: Direct checkpoint activation as a strategy against cancer

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 5, 2003, Pages 2674-2678

  Li, Youzhi ^a   Sun, Xiangao ^b   LaMont, J Thomas ^a   Pardee, Arthur B ^b   Li, Chiang J ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LAPACHONE; CYCLIN DEPENDENT KINASE; DIMETHYL SULFOXIDE; DNA; TRANSCRIPTION FACTOR E2F;

APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE; CELL DEATH; CELL GROWTH; COLONY FORMATION; CONTROLLED STUDY; DNA BINDING; ENZYME ASSAY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PRIORITY JOURNAL;

ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE; CELL CYCLE PROTEINS; CELL DEATH; CELL DIVISION; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; COLORING AGENTS; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; E2F TRANSCRIPTION FACTORS; E2F1 TRANSCRIPTION FACTOR; FLOW CYTOMETRY; HUMANS; MODELS, BIOLOGICAL; NAPHTHOQUINONES; NEOPLASMS; RETINOBLASTOMA PROTEIN; S PHASE; TETRAZOLIUM SALTS; THIAZOLES; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 0344406759     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0538044100     Document Type: Article

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