Efficacy of siRNA nanocapsules targeted against the EWS-Fli1 oncogene in Ewing sarcoma

Pharmaceutical Research

Volumn 23, Issue 5, 2006, Pages 892-900

  Toub, Nedjma ^a,b   Bertrand, Jean Rémi ^b   Tamaddon, Ali ^b   Elhamess, Hind ^b   Hillaireau, Hervé ^a   Maksimenko, Andrei ^b   Maccario, Jean ^c   Malvy, Claude ^b   Fattal, Elias ^a   Couvreur, Patrick ^a  

^a UNIV PARIS SUD   (France)

^b CNRS   (France)

^c Centre Pharmaceutique   (France)

Author keywords

Ewing sarcoma; EWS Fli1; Isobutylcyanoacrylate; Nanocapsules; siRNA

Indexed keywords

BUCRILATE; MESSENGER RNA; NANOCAPSULE; POLYISOBUTYLCYANOACRYLATE; RNA BINDING PROTEIN EWS; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FLI 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIODEGRADABILITY; CANCER CELL; CANCER INHIBITION; CELL MEMBRANE PERMEABILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; DOSE RESPONSE; DRUG DEGRADATION; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG PENETRATION; DRUG SYNTHESIS; DRUG TARGETING; EMBRYO; ENCAPSULATION; EWING SARCOMA; FIBROBLAST; FUSION GENE; MOUSE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; RNA SEQUENCE; TUMOR XENOGRAFT;

ANIMALS; CYANOACRYLATES; FIBROBLASTS; MICE; MICE, NUDE; NANOPARTICLES; NANOTECHNOLOGY; NIH 3T3 CELLS; ONCOGENE PROTEINS, FUSION; POLYMERS; PROTO-ONCOGENE PROTEIN C-FLI-1; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; RNA-BINDING PROTEIN EWS; SARCOMA, EWING'S; TIME FACTORS; TRANSFECTION;

EID: 33646878087     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-006-9901-9     Document Type: Article

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