메뉴 건너뛰기




Volumn 178, Issue 9, 2007, Pages 5820-5827

MyD88-mediated instructive signals in dendritic cells regulate pulmonary immune responses during respiratory virus infection

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR;

EID: 34247567868     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.9.5820     Document Type: Article
Times cited : (68)

References (53)
  • 2
    • 0037323548 scopus 로고    scopus 로고
    • Respiratory syncytial virus epidemics: The ups and downs of a seasonal virus
    • Stensballe, L. G., J. K. Devasundaram, and E. A. Simoes. 2003. Respiratory syncytial virus epidemics: the ups and downs of a seasonal virus. Pediatr. Infect. Dis. J. 22: S21-S32.
    • (2003) Pediatr. Infect. Dis. J , vol.22
    • Stensballe, L.G.1    Devasundaram, J.K.2    Simoes, E.A.3
  • 3
    • 0344585033 scopus 로고    scopus 로고
    • Review of epidemiology and clinical risk factors for severe respiratory syncytial virus (RSV) infection
    • Welliver, R. C. 2003. Review of epidemiology and clinical risk factors for severe respiratory syncytial virus (RSV) infection. J. Pediatr. 143: S112-S117.
    • (2003) J. Pediatr , vol.143
    • Welliver, R.C.1
  • 4
    • 0346494513 scopus 로고    scopus 로고
    • Viral infections, atopy, and asthma: Is there a causal relationship?
    • Peebles, R. S., Jr. 2004. Viral infections, atopy, and asthma: is there a causal relationship? J. Allergy Clin. Immunol. 113: S15-S18.
    • (2004) J. Allergy Clin. Immunol , vol.113
    • Peebles Jr., R.S.1
  • 6
    • 0027448007 scopus 로고
    • Pathogenesis and treatment of bronchiolitis
    • Lugo, R. A., and M. C. Nahata. 1993. Pathogenesis and treatment of bronchiolitis. Clin. Pharm. 12: 95-116.
    • (1993) Clin. Pharm , vol.12 , pp. 95-116
    • Lugo, R.A.1    Nahata, M.C.2
  • 7
    • 0032400916 scopus 로고    scopus 로고
    • Host genetic determinants of vaccine-induced eosinophilia during respiratory syncytial virus infection
    • Hussell, T., A. Georgiou, T. E. Sparer, S. Matthews, P. Pala, and P. J. Openshaw. 1998. Host genetic determinants of vaccine-induced eosinophilia during respiratory syncytial virus infection. J. Immunol. 161: 6215-6222.
    • (1998) J. Immunol , vol.161 , pp. 6215-6222
    • Hussell, T.1    Georgiou, A.2    Sparer, T.E.3    Matthews, S.4    Pala, P.5    Openshaw, P.J.6
  • 9
    • 31144451555 scopus 로고    scopus 로고
    • Deletion of TLR3 alters the pulmonary immune environment and mucus production during respiratory syncytial virus infection
    • Rudd, B. D., J. J. Smit, R. A. Flavell, L. Alexopoulou, M. A. Schaller, A. Gruber, A. A. Berlin, and N. W. Lukacs. 2006. Deletion of TLR3 alters the pulmonary immune environment and mucus production during respiratory syncytial virus infection. J. Immunol. 176: 1937-1942.
    • (2006) J. Immunol , vol.176 , pp. 1937-1942
    • Rudd, B.D.1    Smit, J.J.2    Flavell, R.A.3    Alexopoulou, L.4    Schaller, M.A.5    Gruber, A.6    Berlin, A.A.7    Lukacs, N.W.8
  • 10
    • 0035284898 scopus 로고    scopus 로고
    • IL-13-induced airway hyperreactivity during respiratory syncytial virus infection is STAT6 dependent
    • Tekkanat, K. K., H. F. Maassab, D. S. Cho, J. J. Lai, A. John, A. Berlin, M. H. Kaplan, and N. W. Lukacs. 2001. IL-13-induced airway hyperreactivity during respiratory syncytial virus infection is STAT6 dependent. J. Immunol. 166: 3542-3548.
    • (2001) J. Immunol , vol.166 , pp. 3542-3548
    • Tekkanat, K.K.1    Maassab, H.F.2    Cho, D.S.3    Lai, J.J.4    John, A.5    Berlin, A.6    Kaplan, M.H.7    Lukacs, N.W.8
  • 11
    • 0035879289 scopus 로고    scopus 로고
    • Respiratory syncytial virus predisposes mice to augmented allergic airway responses via IL-13-mediated mechanisms
    • Lukacs, N. W., K. K. Tekkanat, A. Berlin, C. M. Hogaboam, A. Miller, H. Evanoff, P. Lincoln, and H. Maassab. 2001. Respiratory syncytial virus predisposes mice to augmented allergic airway responses via IL-13-mediated mechanisms. J. Immunol. 167: 1060-1065.
    • (2001) J. Immunol , vol.167 , pp. 1060-1065
    • Lukacs, N.W.1    Tekkanat, K.K.2    Berlin, A.3    Hogaboam, C.M.4    Miller, A.5    Evanoff, H.6    Lincoln, P.7    Maassab, H.8
  • 12
    • 22544462193 scopus 로고    scopus 로고
    • The enhancement or prevention of airway hyperresponsiveness during reinfection with respiratory syncytial virus is critically dependent on the age at first infection and IL-13 production
    • Dakhama, A., J. W. Park, C. Taube, A. Joetham, A. Balhorn, N. Miyahara, K. Takeda, and E. W. Gelfand. 2005. The enhancement or prevention of airway hyperresponsiveness during reinfection with respiratory syncytial virus is critically dependent on the age at first infection and IL-13 production. J. Immunol. 175: 1876-1883.
    • (2005) J. Immunol , vol.175 , pp. 1876-1883
    • Dakhama, A.1    Park, J.W.2    Taube, C.3    Joetham, A.4    Balhorn, A.5    Miyahara, N.6    Takeda, K.7    Gelfand, E.W.8
  • 13
    • 0034880117 scopus 로고    scopus 로고
    • Role of interleukin-12 and stat-4 in the regulation of airway inflammation and hyperreactivity in respiratory syncytial virus infection
    • Tekkanat, K. K., H. Maassab, A. A. Berlin, P. M. Lincoln, H. L. Evanoff, M. H. Kaplan, and N. W. Lukacs. 2001. Role of interleukin-12 and stat-4 in the regulation of airway inflammation and hyperreactivity in respiratory syncytial virus infection. Am. J. Pathol. 159: 631-638.
    • (2001) Am. J. Pathol , vol.159 , pp. 631-638
    • Tekkanat, K.K.1    Maassab, H.2    Berlin, A.A.3    Lincoln, P.M.4    Evanoff, H.L.5    Kaplan, M.H.6    Lukacs, N.W.7
  • 14
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • Trinchieri, G. 2003. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 3: 133-146.
    • (2003) Nat. Rev. Immunol , vol.3 , pp. 133-146
    • Trinchieri, G.1
  • 15
    • 0037232254 scopus 로고    scopus 로고
    • Toll-like receptors and their function in innate and adaptive immunity
    • Heine, H., and E. Lien. 2003. Toll-like receptors and their function in innate and adaptive immunity. Int. Arch. Allergy Immunol. 130: 180-192.
    • (2003) Int. Arch. Allergy Immunol , vol.130 , pp. 180-192
    • Heine, H.1    Lien, E.2
  • 16
    • 0038714270 scopus 로고    scopus 로고
    • Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFκ B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR
    • Jiang, Z., M. Zamanian-Daryoush, H. Nie, A. M. Silva, B. R. Williams, and X. Li. 2003. Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFκ B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR. J. Biol. Chem. 278: 16713-16719.
    • (2003) J. Biol. Chem , vol.278 , pp. 16713-16719
    • Jiang, Z.1    Zamanian-Daryoush, M.2    Nie, H.3    Silva, A.M.4    Williams, B.R.5    Li, X.6
  • 17
    • 0742324860 scopus 로고    scopus 로고
    • TLR signaling pathways
    • Takeda, K., and S. Akira. 2004. TLR signaling pathways. Semin. Immunol. 16: 3-9.
    • (2004) Semin. Immunol , vol.16 , pp. 3-9
    • Takeda, K.1    Akira, S.2
  • 18
    • 0036604930 scopus 로고    scopus 로고
    • Control of adaptive immune responses by Toll-like receptors
    • Barton, G. M., and R. Medzhitov. 2002. Control of adaptive immune responses by Toll-like receptors. Curr. Opin. Immunol. 14: 380-383.
    • (2002) Curr. Opin. Immunol , vol.14 , pp. 380-383
    • Barton, G.M.1    Medzhitov, R.2
  • 19
    • 23844549973 scopus 로고    scopus 로고
    • Notch ligands Δ-like1, Δ-like4 and Jagged1 differentially regulate activation of peripheral T helper cells
    • Rutz, S., B. Mordmuller, S. Sakano, and A. Scheffold. 2005. Notch ligands Δ-like1, Δ-like4 and Jagged1 differentially regulate activation of peripheral T helper cells. Eur. J. Immunol. 35: 2443-2451.
    • (2005) Eur. J. Immunol , vol.35 , pp. 2443-2451
    • Rutz, S.1    Mordmuller, B.2    Sakano, S.3    Scheffold, A.4
  • 20
    • 22144492615 scopus 로고    scopus 로고
    • Minter, L. M., D. M. Turley, P. Das, H. M. Shin, I. Joshi, R. G. Lawlor, O. H..Cho, T. Palaga, S. Gottipati, J. C. Telfer, et al. 2005. Inhibitors of γ-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. Nat. Immunol. 6: 680-688.
    • Minter, L. M., D. M. Turley, P. Das, H. M. Shin, I. Joshi, R. G. Lawlor, O. H..Cho, T. Palaga, S. Gottipati, J. C. Telfer, et al. 2005. Inhibitors of γ-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. Nat. Immunol. 6: 680-688.
  • 21
    • 2342496710 scopus 로고    scopus 로고
    • Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells
    • Amsen, D., J. M. Blander, G. R. Lee, K. Tanigaki, T. Honjo, and R. A. Flavell. 2004. Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells. Cell 117: 515-526.
    • (2004) Cell , vol.117 , pp. 515-526
    • Amsen, D.1    Blander, J.M.2    Lee, G.R.3    Tanigaki, K.4    Honjo, T.5    Flavell, R.A.6
  • 22
    • 0346035760 scopus 로고    scopus 로고
    • CXCR2 regulates respiratory syncytial virus-induced airway hyperreactivity and mucus overproduction
    • Miller, A. L., R. M. Strieter, A. D. Gruber, S. B. Ho, and N. W. Lukacs. 2003. CXCR2 regulates respiratory syncytial virus-induced airway hyperreactivity and mucus overproduction. J. Immunol. 170: 3348-3356.
    • (2003) J. Immunol , vol.170 , pp. 3348-3356
    • Miller, A.L.1    Strieter, R.M.2    Gruber, A.D.3    Ho, S.B.4    Lukacs, N.W.5
  • 23
    • 2142808245 scopus 로고    scopus 로고
    • Respiratory syncytial virus-induced chemokine production: Linking viral replication to chemokine production in vitro and in vivo
    • Miller, A. L., T. L. Bowlin, and N. W. Lukacs. 2004. Respiratory syncytial virus-induced chemokine production: linking viral replication to chemokine production in vitro and in vivo. J. Infect. Dis. 189: 1419-1430.
    • (2004) J. Infect. Dis , vol.189 , pp. 1419-1430
    • Miller, A.L.1    Bowlin, T.L.2    Lukacs, N.W.3
  • 24
    • 33646676046 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells inhibit pulmonary immunopathology and promote clearance of respiratory syncytial virus
    • Smit, J. J., B. D. Rudd, and N. W. Lukacs. 2006. Plasmacytoid dendritic cells inhibit pulmonary immunopathology and promote clearance of respiratory syncytial virus. J. Exp. Med. 203: 1153-1159.
    • (2006) J. Exp. Med , vol.203 , pp. 1153-1159
    • Smit, J.J.1    Rudd, B.D.2    Lukacs, N.W.3
  • 25
    • 0346035760 scopus 로고    scopus 로고
    • CXCR2 regulates respiratory syncytial virus-induced airway hyperreactivity and mucus overproduction
    • Miller, A. L., R. M. Strieter, A. D. Gruber, S. B. Ho, and N. W. Lukacs. 2003. CXCR2 regulates respiratory syncytial virus-induced airway hyperreactivity and mucus overproduction. J. Immunol. 170: 3348-3356.
    • (2003) J. Immunol , vol.170 , pp. 3348-3356
    • Miller, A.L.1    Strieter, R.M.2    Gruber, A.D.3    Ho, S.B.4    Lukacs, N.W.5
  • 27
    • 33744748625 scopus 로고    scopus 로고
    • Regulation of mucin genes in chronic inflammatory airway diseases
    • Voynow, J. A., S. J. Gendler, and M. C. Rose. 2006. Regulation of mucin genes in chronic inflammatory airway diseases. Am. J. Respir. Cell Mol. Biol. 34: 661-665.
    • (2006) Am. J. Respir. Cell Mol. Biol , vol.34 , pp. 661-665
    • Voynow, J.A.1    Gendler, S.J.2    Rose, M.C.3
  • 30
    • 20344389060 scopus 로고    scopus 로고
    • Toll-like receptors: Linking innate and adaptive immunity
    • Pasare, C, and R. Medzhitov. 2005. Toll-like receptors: linking innate and adaptive immunity. Adv. Exp. Med. Biol. 560: 11-18.
    • (2005) Adv. Exp. Med. Biol , vol.560 , pp. 11-18
    • Pasare, C.1    Medzhitov, R.2
  • 31
    • 23944489407 scopus 로고    scopus 로고
    • Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
    • Napolitani, G., A. Rinaldi, F. Bertoni, F. Sallusto, and A. Lanzavecchia. 2005. Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat. Immunol. 6: 769-776.
    • (2005) Nat. Immunol , vol.6 , pp. 769-776
    • Napolitani, G.1    Rinaldi, A.2    Bertoni, F.3    Sallusto, F.4    Lanzavecchia, A.5
  • 33
    • 27744497439 scopus 로고    scopus 로고
    • Essential role of the MyD88 pathway, but nonessential roles of TLRs 2, 4, and 9, in the adjuvant effect promoting Th1-mediated autoimmunity
    • Su, S. B., P. B. Silver, R. S. Grajewski, R. K. Agarwal, J. Tang, C. C. Chan, and R. R. Caspi. 2005. Essential role of the MyD88 pathway, but nonessential roles of TLRs 2, 4, and 9, in the adjuvant effect promoting Th1-mediated autoimmunity. J. Immunol. 175: 6303-6310.
    • (2005) J. Immunol , vol.175 , pp. 6303-6310
    • Su, S.B.1    Silver, P.B.2    Grajewski, R.S.3    Agarwal, R.K.4    Tang, J.5    Chan, C.C.6    Caspi, R.R.7
  • 35
    • 0345714673 scopus 로고    scopus 로고
    • High levels of susceptibility and T helper 2 response in MyD88-deficient mice infected with Leishmania major are interleukin-4 dependent
    • Debus, A., J. Glasner, M. Rollinghoff, and A. Gessner. 2003. High levels of susceptibility and T helper 2 response in MyD88-deficient mice infected with Leishmania major are interleukin-4 dependent. Infect. Immun. 71: 7215-7218.
    • (2003) Infect. Immun , vol.71 , pp. 7215-7218
    • Debus, A.1    Glasner, J.2    Rollinghoff, M.3    Gessner, A.4
  • 36
    • 0036312668 scopus 로고    scopus 로고
    • Endotoxin can induce MyD88-deficient dendritic cells to support Th2 cell differentiation
    • Kaisho, T., K. Hoshino, T. Iwabe, O. Takeuchi, T. Yasui, and S. Akira. 2002. Endotoxin can induce MyD88-deficient dendritic cells to support Th2 cell differentiation. Int. Immunol. 14: 695-700.
    • (2002) Int. Immunol , vol.14 , pp. 695-700
    • Kaisho, T.1    Hoshino, K.2    Iwabe, T.3    Takeuchi, O.4    Yasui, T.5    Akira, S.6
  • 38
    • 0029077326 scopus 로고
    • IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis
    • Scharton-Kersten, T., L. C. Afonso, M. Wysocka, G. Trinchieri, and P. Scott. 1995. IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis. J. Immunol. 154: 5320-5330.
    • (1995) J. Immunol , vol.154 , pp. 5320-5330
    • Scharton-Kersten, T.1    Afonso, L.C.2    Wysocka, M.3    Trinchieri, G.4    Scott, P.5
  • 39
    • 0030002111 scopus 로고    scopus 로고
    • Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response
    • Mattner, F., J. Magram, J. Ferrante, P. Launois, K. Di Padova, R. Behin, M. K. Gately, J. A. Louis, and G. Alber. 1996. Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response. Eur. J. Immunol. 26: 1553-1559.
    • (1996) Eur. J. Immunol , vol.26 , pp. 1553-1559
    • Mattner, F.1    Magram, J.2    Ferrante, J.3    Launois, P.4    Di Padova, K.5    Behin, R.6    Gately, M.K.7    Louis, J.A.8    Alber, G.9
  • 40
    • 0029099861 scopus 로고
    • Interleukin-12 treatment during immunization elicits a T helper cell type 1-like immune response in mice challenged with respiratory syncytial virus and improves vaccine immunogenicity
    • Tang, Y. W., and B. S. Graham. 1995. Interleukin-12 treatment during immunization elicits a T helper cell type 1-like immune response in mice challenged with respiratory syncytial virus and improves vaccine immunogenicity. J. Infect. Dis. 172: 734-738.
    • (1995) J. Infect. Dis , vol.172 , pp. 734-738
    • Tang, Y.W.1    Graham, B.S.2
  • 41
    • 0031010847 scopus 로고    scopus 로고
    • T cell source of type 1 cytokines determines illness patterns in respiratory syncytial virus-infected mice
    • Tang, Y. W., and B. S. Graham. 1997. T cell source of type 1 cytokines determines illness patterns in respiratory syncytial virus-infected mice. J. Clin. Invest. 99: 2183-2191.
    • (1997) J. Clin. Invest , vol.99 , pp. 2183-2191
    • Tang, Y.W.1    Graham, B.S.2
  • 42
    • 0031616713 scopus 로고    scopus 로고
    • The effect of IL-12 treatment on vaccine-enhanced illness during infection with respiratory syncytial virus
    • Openshaw, P. J., and T. Hussell. 1998. The effect of IL-12 treatment on vaccine-enhanced illness during infection with respiratory syncytial virus. Dev. Biol. Stand 92: 179-185.
    • (1998) Dev. Biol. Stand , vol.92 , pp. 179-185
    • Openshaw, P.J.1    Hussell, T.2
  • 43
    • 0036200715 scopus 로고    scopus 로고
    • Effect of lack of interleukin-4, interleukin-12, interleukin-18, or the interferon-γ receptor on virus replication, cytokine response, and lung pathology during respiratory syncytial virus infection in mice
    • Boelen, A., J. Kwakkel, M. Barends, L. de Rond, J. Dormans, and T. Kimman. 2002. Effect of lack of interleukin-4, interleukin-12, interleukin-18, or the interferon-γ receptor on virus replication, cytokine response, and lung pathology during respiratory syncytial virus infection in mice. J. Med. Virol. 66: 552-560.
    • (2002) J. Med. Virol , vol.66 , pp. 552-560
    • Boelen, A.1    Kwakkel, J.2    Barends, M.3    de Rond, L.4    Dormans, J.5    Kimman, T.6
  • 45
    • 33645506145 scopus 로고    scopus 로고
    • Treg-mediated immunosuppression involves activation of the notch-HES1 axis by membrane-bound TGF-β
    • Ostroukhova, M., Z. Qi, T. B. Oriss, B. Dixon-McCarthy, P. Ray, and A. Ray. 2006. Treg-mediated immunosuppression involves activation of the notch-HES1 axis by membrane-bound TGF-β. J. Clin. Invest. 116: 996-1004.
    • (2006) J. Clin. Invest , vol.116 , pp. 996-1004
    • Ostroukhova, M.1    Qi, Z.2    Oriss, T.B.3    Dixon-McCarthy, B.4    Ray, P.5    Ray, A.6
  • 48
    • 0034768425 scopus 로고    scopus 로고
    • Involvement of Toll-like receptor 4 in innate immunity to respiratory syncytial virus
    • Haynes, L. M., D. D. Moore, E. A. Kurt-Jones, R. W. Finberg, L. J. Anderson, and R. A. Tripp. 2001. Involvement of Toll-like receptor 4 in innate immunity to respiratory syncytial virus. J. Virol. 75: 10730-10737.
    • (2001) J. Virol , vol.75 , pp. 10730-10737
    • Haynes, L.M.1    Moore, D.D.2    Kurt-Jones, E.A.3    Finberg, R.W.4    Anderson, L.J.5    Tripp, R.A.6
  • 49
    • 0036838764 scopus 로고    scopus 로고
    • Respiratory syncytial virus-induced activation of nuclear factor-κB in the lung involves alveolar macrophages and Toll-like receptor 4-dependent pathways
    • Haeberle, H. A., R. Takizawa, A. Casola, A. R. Brasier, H. J. Dieterich, N. Van Rooijen, Z. Gatalica, and R. P. Garofalo. 2002. Respiratory syncytial virus-induced activation of nuclear factor-κB in the lung involves alveolar macrophages and Toll-like receptor 4-dependent pathways. J. Infect. Dis. 186: 1199-1206.
    • (2002) J. Infect. Dis , vol.186 , pp. 1199-1206
    • Haeberle, H.A.1    Takizawa, R.2    Casola, A.3    Brasier, A.R.4    Dieterich, H.J.5    Van Rooijen, N.6    Gatalica, Z.7    Garofalo, R.P.8
  • 51
    • 0036449063 scopus 로고    scopus 로고
    • Signal transduction pathways activated by the IL-1 receptor/Toll-like receptor superfamily
    • O'Neill, L. A. 2002. Signal transduction pathways activated by the IL-1 receptor/Toll-like receptor superfamily. Curr. Top. Microbiol. Immunol. 270: 47-61.
    • (2002) Curr. Top. Microbiol. Immunol , vol.270 , pp. 47-61
    • O'Neill, L.A.1
  • 52
    • 0034304668 scopus 로고    scopus 로고
    • The Toll/interleukin-1 receptor domain: A molecular switch for inflammation and host defense
    • O'Neill, L. 2000. The Toll/interleukin-1 receptor domain: a molecular switch for inflammation and host defense. Biochem. Soc. Trans. 28: 557-563.
    • (2000) Biochem. Soc. Trans , vol.28 , pp. 557-563
    • O'Neill, L.1
  • 53
    • 4644319014 scopus 로고    scopus 로고
    • IL-12p40 and IL-18 modulate inflammatory and immune responses to respiratory syncytial virus infection
    • Wang, S. Z., Y. X. Bao, C. L. Rosenberger, Y. Tesfaigzi, J. M. Stark, and K. S. Harrod. 2004. IL-12p40 and IL-18 modulate inflammatory and immune responses to respiratory syncytial virus infection. J. Immunol. 173: 4040-4049.
    • (2004) J. Immunol , vol.173 , pp. 4040-4049
    • Wang, S.Z.1    Bao, Y.X.2    Rosenberger, C.L.3    Tesfaigzi, Y.4    Stark, J.M.5    Harrod, K.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.