Plasmacytoid dendritic cells inhibit pulmonary immunopathology and promote clearance of respiratory syncytial virus

Journal of Experimental Medicine

Volumn 203, Issue 5, 2006, Pages 1153-1159

  Smit, Joost J ^a   Rudd, Brian D ^a   Lukacs, Nicholas W ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CLEARANCE; CONTROLLED STUDY; DENDRITIC CELL; DEPLETION; DISEASE EXACERBATION; FEMALE; IMMUNOPATHOLOGY; MOUSE; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; VIRUS INFECTION;

ADULT; ANIMALS; CELL MOVEMENT; DENDRITIC CELLS; FEMALE; HUMANS; IMMUNITY, NATURAL; INFANT; INFLAMMATION; LUNG; MICE; MICE, INBRED BALB C; PLASMA CELLS; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUS, HUMAN;

EID: 33646676046     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20052359     Document Type: Article

References (26)

1. Falsey, A.R., P.A. Hennessey, M.A. Formica, C. Cox, and E.E. Walsh. 2005. Respiratory syncytial virus infection in elderly and high-risk adults. N. Engl. J. Med. 352:1749-1759.
2. Hall, C.B. 2001. Respiratory syncytial virus and parainfluenza virus. N. Engl. J. Med. 344:1917-1928.
3. Sigurs, N., P.M. Gustafsson, R. Bjarnason, F. Lundberg, S. Schmidt, F. Sigurbergsson, and B. Kjellman. 2005. Severe respiratory syncytial virus bronchiolitis in infancy and asthma and allergy at age 13. Am. J. Respir. Crit. Care Med. 171:137-141.
4. Kim, H.W., J.G. Canchola, C.D. Brandt, G. Pyles, R.M. Chanock, K. Jensen, and R.H. Parrott. 1969. Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccine. Am. J. Epidemiol. 89:422-434.
5. Peebles, R.S., Jr., and B.S. Graham. 2005. Pathogenesis of respiratory syncytial virus infection in the murine model. Proc. Am. Thorac. Soc. 2:110-115.
6. Tekkanat, K.K., H.F. Maassab, D.S. Cho, J.J. Lai, A. John, A. Berlin, M.H. Kaplan, and N.W. Lukacs. 2001. IL-13-induced airway hyperreactivity during respiratory syncytial virus infection is STAT6 dependent. J. Immunol. 166:3542-3548.
7. Vermaelen, K., and R. Pauwels. 2005. Pulmonary dendritic cells. Am. J. Respir. Crit. Care Med. 172:530-551.
8. + dendritic cells during allergen challenge abrogates the characteristic features of asthma. J. Exp. Med. 201:981-991.
9. Steinman, R.M. 2003. Some interfaces of dendritic cell biology. APMIS. 111:675-697.
10. Dahl, M.E., K. Dabbagh, D. Liggitt, S. Kim, and D.B. Lewis. 2004. Viral-induced T helper type 1 responses enhance allergic disease by effects on lung dendritic cells. Nat. Immunol. 5:337-343.
11. Belz, G.T., C.M. Smith, L. Kleinert, P. Reading, A. Brooks, K. Shortman, F.R. Carbone, and W.R. Heath. 2004. Distinct migrating and nonmigrating dendritic cell populations are involved in MHC class I-restricted antigen presentation after lung infection with virus. Proc. Natl. Acad. Sci. USA. 101:8670-8675.
12. Beyer, M., H. Bartz, K. Horner, S. Doths, C. Koerner-Rettberg, and J. Schwarze. 2004. Sustained increases in numbers of pulmonary dendritic cells after respiratory syncytial virus infection. J. Allergy Clin. Immunol. 113:127-133.
13. Gill, M.A., A.K. Palucka, T. Barton, F. Ghaff ar, H. Jafri, J. Banchereau, and O. Ramilo. 2005. Mobilization of plasmacytoid and myeloid dendritic cells to mucosal sites in children with respiratory syncytial virus and other viral respiratory infections. J. Infect. Dis. 191:1105-1115.
14. Schwarze, J., D.R. O'Donnell, A. Rohwedder, and P.J. Openshaw. 2004. Latency and persistence of respiratory syncytial virus despite T cell immunity. Am. J. Respir. Crit. Care Med. 169:801-805.
15. Cubie, H.A., L.A. Duncan, L.A. Marshall, and N.M. Smith. 1997. Detection of respiratory syncytial virus nucleic acid in archival postmortem tissue from infants. Pediatr. Pathol. Lab. Med. 17:927-938.
16. + T cells in airway infl ammation and tolerance. J. Immunol. 174:854-863.
17. de Heer, H.J., H. Hammad, T. Soullie, D. Hijdra, N. Vos, M.A. Willart, H.C. Hoogsteden, and B.N. Lambrecht. 2004. Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen. J. Exp. Med. 200:89-98.
18. Demedts, I.K., G.G. Brusselle, K.Y. Vermaelen, and R.A. Pauwels. 2005. Identification and characterization of human pulmonary dendritic cells. Am. J. Respir. Cell Mol. Biol. 32:177-184.
19. Colonna, M., G. Trinchieri, and Y.J. Liu. 2004. Plasmacytoid dendritic cells in immunity. Nat. Immunol. 5:1219-1226.
20. Cella, M., D. Jarrossay, F. Facchetti, O. Alebardi, H. Nakajima, A. Lanzavecchia, and M. Colonna. 1999. Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon. Nat. Med. 5:919-923.
21. Le Bon, A., G. Schiavoni, G. D'Agostino, I. Gresser, F. Belardelli, and D.F. Tough. 2001. Type I interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo. Immunity. 14:461-470.
22. Hashimoto, K., J.E. Durbin, W. Zhou, R.D. Collins, S.B. Ho, J.K. Kolls, P.J. Dubin, J.R. Sheller, K. Goleniewska, J.F. O'Neal, et al. 2005. Respiratory syncytial virus infection in the absence of STAT 1 results in airway dysfunction, airway mucus, and augmented IL-17 levels. J. Allergy Clin. Immunol. 116:550-557.
23. Johnson, T.R., S.E. Mertz, N. Gitiban, S. Hammond, R. Legallo, R.K. Durbin, and J.E. Durbin. 2005. Role for innate IFNs in determining respiratory syncytial virus immunopathology. J. Immunol. 174:7234-7241.
24. Guerrero-Plata, A., S. Baron, J.S. Poast, P.A. Adegboyega, A. Casola, and R.P. Garofalo. 2005. Activity and regulation of α interferon in respiratory syncytial virus and human metapneumovirus experimental infections. J. Virol. 79:10190-10199.
25. Miller, A.L., T.L. Bowlin, and N.W. Lukacs. 2004. Respiratory syncytial virus-induced chemokine production: linking viral replication to chemokine production in vitro and in vivo. J. Infect. Dis. 189:1419-1430.
26. Asselin-Paturel, C., G. Brizard, J.J. Pin, F. Briere, and G. Trinchieri. 2003. Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody. J. Immunol. 171:6466-6477.