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Volumn 71, Issue 12, 2003, Pages 7215-7218

High Levels of Susceptibility and T Helper 2 Response in MyD88-Deficient Mice Infected with Leishmania major Are Interleukin-4 Dependent

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 12; INTERLEUKIN 4; MYELOID DIFFERENTIATION FACTOR 88;

EID: 0345714673     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.71.12.7215-7218.2003     Document Type: Article
Times cited : (60)

References (27)
  • 2
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: Critical proteins linking innate and acquired immunity
    • Akira, S., K. Takeda, and T. Kaisho. 2001. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2:675-680.
    • (2001) Nat. Immunol. , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 5
    • 0036785557 scopus 로고    scopus 로고
    • MyD88-dependent but Toll-like receptor 2-independent innate immunity to Listeria: No role for either in macrophage listericidal activity
    • Edelson, B. T., and E. R. Unanue. 2002. MyD88-dependent but Toll-like receptor 2-independent innate immunity to Listeria: no role for either in macrophage listericidal activity. J. Immunol. 169:3869-3875.
    • (2002) J. Immunol. , vol.169 , pp. 3869-3875
    • Edelson, B.T.1    Unanue, E.R.2
  • 7
    • 0028048136 scopus 로고
    • Recombinant soluble interleukin-4 (IL-4) receptor acts as an antagonist of IL-4 in murine cutaneous leishmaniasis
    • Gessner, A., K. Schroppel, A. Will, K. H. Enssle, L. Lauffer, and M. Rollinghoff. 1994. Recombinant soluble interleukin-4 (IL-4) receptor acts as an antagonist of IL-4 in murine cutaneous leishmaniasis. Infect. Immun. 62:4112-4117.
    • (1994) Infect. Immun. , vol.62 , pp. 4112-4117
    • Gessner, A.1    Schroppel, K.2    Will, A.3    Enssle, K.H.4    Lauffer, L.5    Rollinghoff, M.6
  • 9
    • 0036630093 scopus 로고    scopus 로고
    • Leishmania major activates IL-1α expression in macrophages through a MyD88-dependent pathway
    • Hawn, T. R., A. Ozinsky, D. M. Underhill, F. S. Buckner, S. Akira, and A. Aderem. 2002. Leishmania major activates IL-1α expression in macrophages through a MyD88-dependent pathway. Microbes Infect. 4:763-771.
    • (2002) Microbes Infect. , vol.4 , pp. 763-771
    • Hawn, T.R.1    Ozinsky, A.2    Underhill, D.M.3    Buckner, F.S.4    Akira, S.5    Aderem, A.6
  • 10
    • 0032520619 scopus 로고    scopus 로고
    • Underproduction of interleukin-12 in susceptible mice during progressive leishmaniasis is due to decreased CD40 activity
    • Heinzel, F. P., R. M. Rerko, and A. M. Hujer. 1998. Underproduction of interleukin-12 in susceptible mice during progressive leishmaniasis is due to decreased CD40 activity. Cell Immunol. 184:129-142.
    • (1998) Cell Immunol. , vol.184 , pp. 129-142
    • Heinzel, F.P.1    Rerko, R.M.2    Hujer, A.M.3
  • 11
    • 0033802387 scopus 로고    scopus 로고
    • Interleukin (IL)-4 is a major regulatory cytokine governing bioactive IL-12 production by mouse and human dendritic cells
    • Hochrein, H., M. O'Keeffe, T. Luft, S. Vandenabeele, R. J. Grumont, E. Maraskovsky, and K. Shortman. 2000. Interleukin (IL)-4 is a major regulatory cytokine governing bioactive IL-12 production by mouse and human dendritic cells. J. Exp. Med. 192:823-833.
    • (2000) J. Exp. Med. , vol.192 , pp. 823-833
    • Hochrein, H.1    O'Keeffe, M.2    Luft, T.3    Vandenabeele, S.4    Grumont, R.J.5    Maraskovsky, E.6    Shortman, K.7
  • 12
    • 0033166472 scopus 로고    scopus 로고
    • Unresponsiveness of MyD88-deficient mice to endotoxin
    • Kawai, T., O. Adachi, T. Ogawa, K. Takeda, and S. Akira. 1999. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11:115-122.
    • (1999) Immunity , vol.11 , pp. 115-122
    • Kawai, T.1    Adachi, O.2    Ogawa, T.3    Takeda, K.4    Akira, S.5
  • 14
    • 0036018493 scopus 로고    scopus 로고
    • Experimental cutaneous leishmaniasis: A powerful model to study in vivo the mechanisms underlying genetic differences in Th subset differentiation
    • Louis, J., A. Gumy, H. Voigt, M. Rocken, and P. Launois. 2002. Experimental cutaneous leishmaniasis: a powerful model to study in vivo the mechanisms underlying genetic differences in Th subset differentiation. Eur. J. Dermatol. 12:316-318.
    • (2002) Eur. J. Dermatol. , vol.12 , pp. 316-318
    • Louis, J.1    Gumy, A.2    Voigt, H.3    Rocken, M.4    Launois, P.5
  • 15
    • 0033564686 scopus 로고    scopus 로고
    • Differences between IL-4- and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling
    • Mohrs, M., B. Ledermann, G. Kohler, A. Dorfmuller, A. Gessner, and F. Brombacher. 1999. Differences between IL-4- and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling. J. Immunol. 162:7302-7308.
    • (1999) J. Immunol. , vol.162 , pp. 7302-7308
    • Mohrs, M.1    Ledermann, B.2    Kohler, G.3    Dorfmuller, A.4    Gessner, A.5    Brombacher, F.6
  • 16
    • 0034040798 scopus 로고    scopus 로고
    • Genetically resistant mice lacking IL-18 gene develop Th1 response and control cutaneous Leishmania major infection
    • Monteforte, G. M., K. Takeda, M. Rodriguez-Sosa, S. Akira, J. R. David, and A. R. Satoskar. 2000. Genetically resistant mice lacking IL-18 gene develop Th1 response and control cutaneous Leishmania major infection. J. Immunol. 164:5890-5893.
    • (2000) J. Immunol. , vol.164 , pp. 5890-5893
    • Monteforte, G.M.1    Takeda, K.2    Rodriguez-Sosa, M.3    Akira, S.4    David, J.R.5    Satoskar, A.R.6
  • 17
    • 0028933795 scopus 로고
    • The regulation of immunity to Leishmania major
    • Reiner, S. L., and R. M. Locksley. 1995. The regulation of immunity to Leishmania major. Annu. Rev. Immunol. 13:151-177.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 151-177
    • Reiner, S.L.1    Locksley, R.M.2
  • 18
    • 0025133974 scopus 로고
    • Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism
    • Sadick, M. D., F. P. Heinzel, B. J. Holaday, R. T. Pu, R. S. Dawkins, and R. M. Locksley. 1990. Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism. J. Exp. Med. 171:115-127.
    • (1990) J. Exp. Med. , vol.171 , pp. 115-127
    • Sadick, M.D.1    Heinzel, F.P.2    Holaday, B.J.3    Pu, R.T.4    Dawkins, R.S.5    Locksley, R.M.6
  • 19
    • 0037097795 scopus 로고    scopus 로고
    • Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells
    • Scanga, C. A., J. Aliberti, D. Jankovic, F. Tilloy, S. Bennouna, E. Y. Denkers, R. Medzhitov, and A. Sher. 2002. Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells. J. Immunol. 168:5997-6001.
    • (2002) J. Immunol. , vol.168 , pp. 5997-6001
    • Scanga, C.A.1    Aliberti, J.2    Jankovic, D.3    Tilloy, F.4    Bennouna, S.5    Denkers, E.Y.6    Medzhitov, R.7    Sher, A.8
  • 20
    • 0029077326 scopus 로고
    • IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis
    • Scharton-Kersten, T., L. C. Afonso, M. Wysocka, G. Trinchieri, and P. Scott. 1995. IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis. J. Immunol. 154:5320-5330.
    • (1995) J. Immunol. , vol.154 , pp. 5320-5330
    • Scharton-Kersten, T.1    Afonso, L.C.2    Wysocka, M.3    Trinchieri, G.4    Scott, P.5
  • 22
    • 0033991292 scopus 로고    scopus 로고
    • The host response to Leishmania infection
    • Solbach, W., and T. Laskay. 2000. The host response to Leishmania infection. Adv. Immunol. 74:275-317.
    • (2000) Adv. Immunol. , vol.74 , pp. 275-317
    • Solbach, W.1    Laskay, T.2
  • 23
    • 0028129526 scopus 로고
    • Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major
    • Stenger, S., H. Thuring, M. Rollinghoff, and C. Bogdan. 1994. Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major. J. Exp. Med. 180:783-793.
    • (1994) J. Exp. Med. , vol.180 , pp. 783-793
    • Stenger, S.1    Thuring, H.2    Rollinghoff, M.3    Bogdan, C.4
  • 24
    • 0036448929 scopus 로고    scopus 로고
    • MyD88 as a bottle neck in Toll/IL-1 signaling
    • Takeuchi, O., and S. Akira. 2002. MyD88 as a bottle neck in Toll/IL-1 signaling. Curr. Top. Microbiol. Immunol. 270:155-167.
    • (2002) Curr. Top. Microbiol. Immunol. , vol.270 , pp. 155-167
    • Takeuchi, O.1    Akira, S.2
  • 25
    • 0034669910 scopus 로고    scopus 로고
    • Cutting edge: ILR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection
    • Takeuchi, O., K. Hoshino, and S. Akira. 2000. Cutting edge: ILR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection. J. Immunol. 165:5392-5396.
    • (2000) J. Immunol. , vol.165 , pp. 5392-5396
    • Takeuchi, O.1    Hoshino, K.2    Akira, S.3
  • 27
    • 0032521881 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis
    • Zimmermann, S., O. Egeter, S. Hausmann, G. B. Lipford, M. Rocken, H. Wagner, and K. Heeg. 1998. CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis. J. Immunol. 160:3627-3630.
    • (1998) J. Immunol. , vol.160 , pp. 3627-3630
    • Zimmermann, S.1    Egeter, O.2    Hausmann, S.3    Lipford, G.B.4    Rocken, M.5    Wagner, H.6    Heeg, K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.