C-terminal proteolysis of prenylated proteins in trypanosomatids and RNA interference of enzymes required for the post-translational processing pathway of farnesylated proteins

Molecular and Biochemical Parasitology

Volumn 153, Issue 2, 2007, Pages 115-124

  Gillespie, John R ^a   Yokoyama, Kohei ^a   Lu, Karen ^a   Eastman, Richard T ^a   Bollinger, James G ^a   Van Voorhis, Wesley C ^a   Gelb, Michael H ^a   Buckner, Frederick S ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

A factor converting enzyme; Leishmania major; Protein farnesyltransferase; Protein prenylation; Ras converting enzyme; RNA interference; Trypanosoma brucei

Indexed keywords

AFC1 ENZYME; CYSTEINE; DIPEPTIDYL CARBOXYPEPTIDASE; PRENYLAMINE; PROTEIN FARNESYLTRANSFERASE; RCE1 ENZYME; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; ESTERIFICATION; EUKARYOTIC CELL; MEMBRANE POTENTIAL; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRENYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; RNA INTERFERENCE; SEQUENCE ALIGNMENT; TRYPANOSOMA BRUCEI;

ALKYL AND ARYL TRANSFERASES; AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; ENDOPEPTIDASES; HUMANS; LEISHMANIA MAJOR; MEMBRANE PROTEINS; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; PROTEIN ISOPRENYLATION; PROTEIN METHYLTRANSFERASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTOZOAN PROTEINS; RNA INTERFERENCE; SACCHAROMYCES CEREVISIAE PROTEINS; SPODOPTERA; TRYPANOSOMA BRUCEI BRUCEI;

EUKARYOTA; LEISHMANIA MAJOR; TRYPANOSOMA BRUCEI; TRYPANOSOMATIDAE;

EID: 34247482458     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2007.02.009     Document Type: Article

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