Identification, functional expression and enzymic analysis of two distinct CaaX proteases from Caenorhabditis elegans

Biochemical Journal

Volumn 370, Issue 3, 2003, Pages 1047-1054

  Cadiñanos, Juan ^a   Schmidt, Walter K ^b   Fueyo, Antonio ^a   Varela, Ignacio ^a   López Otín, Carlos ^a   Freije, José M P ^a  

^a UNIVERSITY OF OVIEDO   (Spain)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

Drug target; Farnesylation; Integral membrane protease; Prenylation; Proteolysis; Ras

Indexed keywords

AMINO ACIDS; BIOLOGICAL MEMBRANES; CARBOXYLATION; CHROMOSOMES; GENES; SENSITIVITY ANALYSIS;

ENZYMIC ANALYSIS;

ENZYME KINETICS;

CYSTEINE; EDETIC ACID; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; ONCOPROTEIN; PHEROMONE; PROTEIN CAAX; PROTEINASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CAENORHABDITIS ELEGANS; CARBOXY TERMINAL SEQUENCE; CHROMOSOME 1; CHROMOSOME 5; ENZYME ACTIVITY; ENZYME ANALYSIS; EUKARYOTE; METHYLATION; NONHUMAN; PRENYLATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PROCESSING;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; ENDOPEPTIDASES; HUMANS; LIPOPROTEINS; MEMBRANE PROTEINS; METALLOENDOPEPTIDASES; METALLOPROTEASES; MOLECULAR SEQUENCE DATA; PROTEIN PROCESSING, POST-TRANSLATIONAL; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

CAENORHABDITIS; CAENORHABDITIS ELEGANS; EUKARYOTA; MAMMALIA; NEMATODA;

EID: 0037444824     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20021514     Document Type: Article

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