Calcium regulates tertiary structure and enzymatic activity of human endometase/matrilysin-2 and its role in promoting human breast cancer cell invasion

Biochemical Journal

Volumn 403, Issue 1, 2007, Pages 31-42

  Lee, Seakwoo ^a   Park, Hyun I ^a   Sang, Qing Xiang Amy ^a  

^a FLORIDA STATE UNIVERSITY   (United States)

Author keywords

Breast cancer cell invasion; Calcium; Endometase; Matrilysin 2; Matrix metalloproteinase 26 (MMP 26)

Indexed keywords

BREAST CANCER CELL INVASION; CALCIUM BINDING; MATRIX METALLOPROTEINASE 26 (MMP-26); PROTEIN STRUCTURE;

BINDING SITES; BIOLOGICAL ORGANS; CALCIUM COMPOUNDS; CELL DEATH; DISEASES; MOLECULAR STRUCTURE;

ENZYMES;

CALCIUM; MATRILYSIN 2; MATRIX METALLOPROTEINASE 26; METALLOPROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CALCIUM BINDING; CELL INVASION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; BASE SEQUENCE; BREAST NEOPLASMS; CALCIUM; DNA PRIMERS; FEMALE; HUMANS; MATRIX METALLOPROTEINASES, SECRETED; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NEOPLASM INVASIVENESS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; RESTRICTION MAPPING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 34147171102     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20061390     Document Type: Article

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