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Volumn 17, Issue 17, 1998, Pages 5238-5248

Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor

Author keywords

Crystal structure; Matrix metalloproteinase; Progelatinase A activator; Proteinase complex; Tissue inhibitor of metalloproteinases

Indexed keywords

COLLAGENASE; TISSUE INHIBITOR OF METALLOPROTEINASE;

EID: 0032167522     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.17.5238     Document Type: Article
Times cited : (324)

References (58)
  • 1
    • 0029019867 scopus 로고
    • The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family
    • Apte, S.S., Olsen, B.R. and Murphy, G. (1995) The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family. J. Biol. Chem., 270, 14313-14318.
    • (1995) J. Biol. Chem. , vol.270 , pp. 14313-14318
    • Apte, S.S.1    Olsen, B.R.2    Murphy, G.3
  • 2
    • 0027412196 scopus 로고
    • ALSCRIPT: A tool to format multiple sequence alignments
    • Barton, G.J. (1993) ALSCRIPT: a tool to format multiple sequence alignments. Protein Eng., 6, 37-40.
    • (1993) Protein Eng. , vol.6 , pp. 37-40
    • Barton, G.J.1
  • 3
    • 0030995022 scopus 로고    scopus 로고
    • Specific, high affinity binding of tissue inhibitor of metalloproteinases-4 (TIMP-4) to the COOH-terminal hemopexin-like domain of human gelatinase A
    • Bigg, H.F., Shi, Y.E., Liu, Y.E., Steffensen, B. and Overall, C.M. (1997) Specific, high affinity binding of tissue inhibitor of metalloproteinases-4 (TIMP-4) to the COOH-terminal hemopexin-like domain of human gelatinase A. J. Biol. Chem., 272, 15496-15500.
    • (1997) J. Biol. Chem. , vol.272 , pp. 15496-15500
    • Bigg, H.F.1    Shi, Y.E.2    Liu, Y.E.3    Steffensen, B.4    Overall, C.M.5
  • 4
    • 0028324076 scopus 로고
    • The X-ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity
    • Bode, W., Reinemer, P., Huber, R., Kleine, T., Schnierer, S. and Tschesche, H. (1994) The X-ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity. EMBO J., 13, 1263-1269.
    • (1994) EMBO J. , vol.13 , pp. 1263-1269
    • Bode, W.1    Reinemer, P.2    Huber, R.3    Kleine, T.4    Schnierer, S.5    Tschesche, H.6
  • 5
    • 0025304303 scopus 로고
    • cDNa cloning and expression of a metalloproteinase inhibitor related to tissue inhibitor of metalloproteinases
    • Boone, T.C. Johnson, M.J., De Cle, Y.A. and Langley, K.E. (1990) cDNA cloning and expression of a metalloproteinase inhibitor related to tissue inhibitor of metalloproteinases. Proc. Natl Acad. Sci. USA, 87, 2800-2804.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 2800-2804
    • Boone, T.C.1    Johnson, M.J.2    De Cle, Y.A.3    Langley, K.E.4
  • 7
    • 0000246042 scopus 로고
    • Simulated annealing in crystallography
    • Brünger, A.T. (1991) Simulated annealing in crystallography. Annu. Rev. Phys. Chem., 42, 197-223.
    • (1991) Annu. Rev. Phys. Chem. , vol.42 , pp. 197-223
    • Brünger, A.T.1
  • 9
    • 0031039965 scopus 로고    scopus 로고
    • Membrane-type-2 matrix metalloproteinase can initiate the processing of progelatinase A and is regulated by the tissue inhibitors of metalloproteinases
    • Butler, G.S., Will, H., Atkinson, S.J. and Murphy, G. (1997) Membrane-type-2 matrix metalloproteinase can initiate the processing of progelatinase A and is regulated by the tissue inhibitors of metalloproteinases. Eur. J. Biochem., 244, 653-657.
    • (1997) Eur. J. Biochem. , vol.244 , pp. 653-657
    • Butler, G.S.1    Will, H.2    Atkinson, S.J.3    Murphy, G.4
  • 12
    • 0028924956 scopus 로고
    • The C-terminal region of membrane type matrix metalloproteinase is a functional transmembrane domain required for progelatinase A activation
    • Cao, J., Sato, H., Takino, T. and Seiki, M. (1995) The C-terminal region of membrane type matrix metalloproteinase is a functional transmembrane domain required for progelatinase A activation. J. Biol. Chem., 270, 801-805.
    • (1995) J. Biol. Chem. , vol.270 , pp. 801-805
    • Cao, J.1    Sato, H.2    Takino, T.3    Seiki, M.4
  • 13
    • 0031978254 scopus 로고    scopus 로고
    • Matrix metalloproteinases and TIMPs: Properties and implications for the rheumatic diseases
    • Cawston, T. (1998) Matrix metalloproteinases and TIMPs: properties and implications for the rheumatic diseases. Mol. Med. Today, 4, 130-137.
    • (1998) Mol. Med. Today , vol.4 , pp. 130-137
    • Cawston, T.1
  • 14
    • 0028103275 scopus 로고
    • The CCP4 suite: Programs for protein crystallography
    • Collaborative Computational Project, Number 4 (1994) The CCP4 suite: programs for protein crystallography. Acta Crystallogr. D, 50, 760-763.
    • (1994) Acta Crystallogr. D , vol.50 , pp. 760-763
  • 16
    • 79952608525 scopus 로고
    • Accurate bond and angle parameters for X-ray protein structure refinement
    • Engh, R.A. and Huber, R. (1991) Accurate bond and angle parameters for X-ray protein structure refinement. Acta Crystallogr. A, 47, 392-400.
    • (1991) Acta Crystallogr. A , vol.47 , pp. 392-400
    • Engh, R.A.1    Huber, R.2
  • 17
    • 0027609916 scopus 로고
    • SETOR: Hardware lighted three-dimensional solid model representations of macromolecules
    • Evans, S.V. (1993) SETOR: hardware lighted three-dimensional solid model representations of macromolecules. J. Mol. Graph., 11, 134-138.
    • (1993) J. Mol. Graph. , vol.11 , pp. 134-138
    • Evans, S.V.1
  • 19
    • 0342502272 scopus 로고    scopus 로고
    • The C-terminal (haemopexin-like) domain structure of human gelatinase A (MMP2): Structural implications for its function
    • Gohlke, U., Gomis-Rüth, F.-X., Crabbe, T., Murphy, G., Docherty, A.J.P. and Bode, W. (1996) The C-terminal (haemopexin-like) domain structure of human gelatinase A (MMP2): structural implications for its function. FEBS Lett., 378, 126-130.
    • (1996) FEBS Lett. , vol.378 , pp. 126-130
    • Gohlke, U.1    Gomis-Rüth, F.-X.2    Crabbe, T.3    Murphy, G.4    Docherty, A.J.P.5    Bode, W.6
  • 20
    • 0030717692 scopus 로고    scopus 로고
    • Tissue inhibitors of metalloproteinases: Structure, regulation and biological functions
    • Gomez, D.E., Alonso, D.F., Yoshiji, H. and Thorgeirsson, U.P. (1997) Tissue inhibitors of metalloproteinases: structure, regulation and biological functions. Eur. J. Cell Biol., 74, 111-122.
    • (1997) Eur. J. Cell Biol. , vol.74 , pp. 111-122
    • Gomez, D.E.1    Alonso, D.F.2    Yoshiji, H.3    Thorgeirsson, U.P.4
  • 21
    • 1842377505 scopus 로고    scopus 로고
    • Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1
    • Gomis-Rüth, F.X. et al. (1997) Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1. Nature, 389, 77-81.
    • (1997) Nature , vol.389 , pp. 77-81
    • Gomis-Rüth, F.X.1
  • 22
    • 0029806813 scopus 로고    scopus 로고
    • Molecular cloning and characterisation of human tissue inhibitor of metalloproteinase 4
    • Green, J., Wang, M., Liu, Y.E., Raymond, L.A., Rosen, C. and Shi, Y.E. (1996) Molecular cloning and characterisation of human tissue inhibitor of metalloproteinase 4. J. Biol. Chem., 271, 30375-30380.
    • (1996) J. Biol. Chem. , vol.271 , pp. 30375-30380
    • Green, J.1    Wang, M.2    Liu, Y.E.3    Raymond, L.A.4    Rosen, C.5    Shi, Y.E.6
  • 23
    • 0030824330 scopus 로고    scopus 로고
    • Mutational study of the amino-terminal domain of human tissue inhibitor of metalloproteinases 1 (TIMP-1) locates an inhibitory region for matrix metalloproteinases
    • Huang, W., Meng, Q., Suzuki, K., Nagase, H. and Brew, K. (1997) Mutational study of the amino-terminal domain of human tissue inhibitor of metalloproteinases 1 (TIMP-1) locates an inhibitory region for matrix metalloproteinases. J. Biol. Chem., 272, 22086-22091.
    • (1997) J. Biol. Chem. , vol.272 , pp. 22086-22091
    • Huang, W.1    Meng, Q.2    Suzuki, K.3    Nagase, H.4    Brew, K.5
  • 24
    • 0029891956 scopus 로고    scopus 로고
    • Processing of a precursor of 72-kilodalton type IV collagenase/ gelatinase A by a recombinant membrane-type 1 matrix metalloproteinase
    • Kinoshita, T., Sato, H., Takino, T., Itoh, M., Akizawa. T. and Seiki, M. (1996) Processing of a precursor of 72-kilodalton type IV collagenase/ gelatinase A by a recombinant membrane-type 1 matrix metalloproteinase. Cancer Res., 56, 2535-2538.
    • (1996) Cancer Res. , vol.56 , pp. 2535-2538
    • Kinoshita, T.1    Sato, H.2    Takino, T.3    Itoh, M.4    Akizawa, T.5    Seiki, M.6
  • 25
    • 0025822038 scopus 로고
    • The complex between a tissue inhibitor of metalloproteinases (TIMP-2) and 72-kDa progelatinase is a metalloproteinase inhibitor
    • Kolkenbrock, H., Orgel, D., Hecker-Kia, A., Noack, W. and Ulbrich, N. (1991) The complex between a tissue inhibitor of metalloproteinases (TIMP-2) and 72-kDa progelatinase is a metalloproteinase inhibitor. Eur. J. Biochem., 198, 775-781.
    • (1991) Eur. J. Biochem. , vol.198 , pp. 775-781
    • Kolkenbrock, H.1    Orgel, D.2    Hecker-Kia, A.3    Noack, W.4    Ulbrich, N.5
  • 27
    • 0026244229 scopus 로고
    • MOLSCRIPT: A program to produce both detailed and schematic plots of proteins
    • Kraulis, P.J. (1991) MOLSCRIPT: a program to produce both detailed and schematic plots of proteins. J. Appl. Crystallogr., 24, 946-950.
    • (1991) J. Appl. Crystallogr. , vol.24 , pp. 946-950
    • Kraulis, P.J.1
  • 28
    • 0000243829 scopus 로고
    • PROCHECK: A programme to check the stereochemical quality of protein structures
    • Laskowski, R.A., MacArthur, M.W., Moss, D.S. and Thornton, J.M. (1993) PROCHECK: a programme to check the stereochemical quality of protein structures. J. Appl. Crystallogr., 26, 283-291.
    • (1993) J. Appl. Crystallogr. , vol.26 , pp. 283-291
    • Laskowski, R.A.1    MacArthur, M.W.2    Moss, D.S.3    Thornton, J.M.4
  • 29
    • 0029644935 scopus 로고
    • Structure of full-length porcine synovial collagenase reveals a C-terminal domain containing a calcium-linked, four-bladed beta-propeller
    • Li, J.-Y. et al. (1995) Structure of full-length porcine synovial collagenase reveals a C-terminal domain containing a calcium-linked, four-bladed beta-propeller. Structure, 3, 541-549.
    • (1995) Structure , vol.3 , pp. 541-549
    • Li, J.-Y.1
  • 30
    • 0030592783 scopus 로고    scopus 로고
    • The recombinant catalytic domain of membrane-type matrix metalloproteinase-1 (MT1-MMP) induces activation of progelatinase A and progelatinase A complexed with TIMP-2
    • Lichte, A., Kolkenbrock, H. and Tschesche, H. (1996) The recombinant catalytic domain of membrane-type matrix metalloproteinase-1 (MT1-MMP) induces activation of progelatinase A and progelatinase A complexed with TIMP-2. FEBS Lett., 397, 277-282.
    • (1996) FEBS Lett. , vol.397 , pp. 277-282
    • Lichte, A.1    Kolkenbrock, H.2    Tschesche, H.3
  • 31
    • 0032579501 scopus 로고    scopus 로고
    • Membrane type-1 matrix metalloprotease and stromelysin-3 cleave more efficiently synthetic substrates containing unusual amino acids in their P1′ positions
    • Mucha, A., Cunisse, P., Kannan, R., Beau, F., Yiotakis, A., Basset, P. and Dive, V. (1998) Membrane type-1 matrix metalloprotease and stromelysin-3 cleave more efficiently synthetic substrates containing unusual amino acids in their P1′ positions. J. Biol. Chem., 273, 2763-2768.
    • (1998) J. Biol. Chem. , vol.273 , pp. 2763-2768
    • Mucha, A.1    Cunisse, P.2    Kannan, R.3    Beau, F.4    Yiotakis, A.5    Basset, P.6    Dive, V.7
  • 32
    • 0029022713 scopus 로고
    • Tissue inhibitors of matrix metalloendopeptidases
    • Murphy, G. and Willenbrock, F. (1995) Tissue inhibitors of matrix metalloendopeptidases. Methods Enzymol., 248, 496-510.
    • (1995) Methods Enzymol. , vol.248 , pp. 496-510
    • Murphy, G.1    Willenbrock, F.2
  • 33
    • 0026521973 scopus 로고
    • The C-terminal domain of 72 kDa gelatinase a is not required for catalysis, but is essential for membrane activation and modulates interactions with tissue inhibitors of metalloproteinases
    • Murphy, G., Willenbrock, F., Ward R.V., Cockett, M.I., Eaton, D. and Docherty, A.J.P. (1992) The C-terminal domain of 72 kDa gelatinase A is not required for catalysis, but is essential for membrane activation and modulates interactions with tissue inhibitors of metalloproteinases. Biochem. J., 283, 637-641.
    • (1992) Biochem. J. , vol.283 , pp. 637-641
    • Murphy, G.1    Willenbrock, F.2    Ward, R.V.3    Cockett, M.I.4    Eaton, D.5    Docherty, A.J.P.6
  • 34
    • 0030957218 scopus 로고    scopus 로고
    • Activation mechanisms of matrix metalloproteinases
    • Nagase, H. (1997) Activation mechanisms of matrix metalloproteinases. Biol. Chem., 378, 151-160.
    • (1997) Biol. Chem. , vol.378 , pp. 151-160
    • Nagase, H.1
  • 35
    • 84920325457 scopus 로고
    • AMoRe: An automated package for molecular replacement
    • Navaza, J. (1994) AMoRe: an automated package for molecular replacement. Acta Crystallogr. Sect A 50, 157-163.
    • (1994) Acta Crystallogr. Sect A , vol.50 , pp. 157-163
    • Navaza, J.1
  • 36
    • 0000732609 scopus 로고
    • Grasp - Graphical representation and analysis of surface properties
    • Nicholls, A., Bharadwaj, R. and Honig, B. (1993) Grasp - graphical representation and analysis of surface properties. Biophys. J., 64, A166.
    • (1993) Biophys. J. , vol.64
    • Nicholls, A.1    Bharadwaj, R.2    Honig, B.3
  • 37
    • 0031025218 scopus 로고    scopus 로고
    • Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules
    • Ohuchi, E., Imai, K., Fujii, Y., Sato, H., Seiki, M. and Okada, Y. (1997) Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules. J. Biol. Chem., 272, 2446-2451.
    • (1997) J. Biol. Chem. , vol.272 , pp. 2446-2451
    • Ohuchi, E.1    Imai, K.2    Fujii, Y.3    Sato, H.4    Seiki, M.5    Okada, Y.6
  • 38
    • 0028935326 scopus 로고
    • Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast and head and neck carcinomas
    • Okada, A., Bellocq, J.-P., Rouyer, N., Chenard, M.-P., Rio, M.-C., Chambon, P. and Basset, P. (1995) Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast and head and neck carcinomas. Proc. Natl Acad. Sci. USA, 92, 2730-2734.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 2730-2734
    • Okada, A.1    Bellocq, J.-P.2    Rouyer, N.3    Chenard, M.-P.4    Rio, M.-C.5    Chambon, P.6    Basset, P.7
  • 39
    • 0030669224 scopus 로고    scopus 로고
    • Kinetic analysis of the binding of human matrix metalloproteinase-2 and -9 to tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2
    • Olson, M.W., Gervasi, D.C. Mobasheri, S. and Fridman, R. (1997) Kinetic analysis of the binding of human matrix metalloproteinase-2 and -9 to tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2. J. Biol. Chem., 272, 29975-29983.
    • (1997) J. Biol. Chem. , vol.272 , pp. 29975-29983
    • Olson, M.W.1    Gervasi, D.C.2    Mobasheri, S.3    Fridman, R.4
  • 40
    • 6844250127 scopus 로고    scopus 로고
    • Membrane-type matrix metalloproteinases 1 and 2 exhibit broad-spectrum proteolytic capacities comparable to many matrix metalloproteinases
    • d'Ortho, M.-P., Will, H., Atkinson, S., Butler, G., Messent, A., Gavrilovic, J., Smith, B., Timpl, R., Zardi, L. and Murphy, G. (1997) Membrane-type matrix metalloproteinases 1 and 2 exhibit broad-spectrum proteolytic capacities comparable to many matrix metalloproteinases. Eur. J. Biochem., 250, 751-757.
    • (1997) Eur. J. Biochem. , vol.250 , pp. 751-757
    • D'Ortho, M.-P.1    Will, H.2    Atkinson, S.3    Butler, G.4    Messent, A.5    Gavrilovic, J.6    Smith, B.7    Timpl, R.8    Zardi, L.9    Murphy, G.10
  • 42
    • 0029885707 scopus 로고    scopus 로고
    • Transmembrane-deletion mutants of the membrane-type matrix metalloproteinase-1 process progelatinase A and express intrinsic matrix-degrading activity
    • Pei, D. and Weiss, S.J. (1996) Transmembrane-deletion mutants of the membrane-type matrix metalloproteinase-1 process progelatinase A and express intrinsic matrix-degrading activity. J. Biol. Chem., 271, 9135-9140.
    • (1996) J. Biol. Chem. , vol.271 , pp. 9135-9140
    • Pei, D.1    Weiss, S.J.2
  • 43
    • 0028040070 scopus 로고
    • Structural implications for the role of the N-terminus in the 'superactivation' of collagenases - A crystallographic study
    • Reinemer, P., Grams, F., Huber, R., Kleine, T., Schnierer, S., Pieper, M., Tschesche, H. and Bode, W. (1994) Structural implications for the role of the N-terminus in the 'superactivation' of collagenases - a crystallographic study. FEBS Lett., 338, 227-233.
    • (1994) FEBS Lett. , vol.338 , pp. 227-233
    • Reinemer, P.1    Grams, F.2    Huber, R.3    Kleine, T.4    Schnierer, S.5    Pieper, M.6    Tschesche, H.7    Bode, W.8
  • 45
    • 0028291737 scopus 로고
    • A matrix metalloproteinase expressed on the surface of invasive tumour cells
    • Sato, H., Takino, T., Okada, Y., Cao, J., Shinagawa, A., Yamamoto, E. and Seiki, M. (1994) A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature, 370, 61-65.
    • (1994) Nature , vol.370 , pp. 61-65
    • Sato, H.1    Takino, T.2    Okada, Y.3    Cao, J.4    Shinagawa, A.5    Yamamoto, E.6    Seiki, M.7
  • 46
    • 0030577022 scopus 로고    scopus 로고
    • Activation of a recombinant membrane type 1-matrix metalloproteinase (MT1-MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)-2
    • Sato, H., Kinoshita, T., Takino, T., Nakayama, K. and Seiki, M. (1996) Activation of a recombinant membrane type 1-matrix metalloproteinase (MT1-MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)-2. FEBS Lett., 393, 101-104.
    • (1996) FEBS Lett. , vol.393 , pp. 101-104
    • Sato, H.1    Kinoshita, T.2    Takino, T.3    Nakayama, K.4    Seiki, M.5
  • 48
    • 0027172634 scopus 로고
    • Plasma membrane-dependent activation of the 72-kDa type IV collagenase is prevented by complex formation with TIMP-2
    • Strongin, A.Y., Marmer, B.L., Grant, G.A. and Goldberg, G.I. (1993) Plasma membrane-dependent activation of the 72-kDa type IV collagenase is prevented by complex formation with TIMP-2. J. Biol. Chem., 268, 14033-14039.
    • (1993) J. Biol. Chem. , vol.268 , pp. 14033-14039
    • Strongin, A.Y.1    Marmer, B.L.2    Grant, G.A.3    Goldberg, G.I.4
  • 50
    • 0029118269 scopus 로고
    • Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library
    • Takino, T., Sato, H., Shinagawa, A. and Seiki, M. (1995) Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. J. Biol. Chem., 270, 23013-23020.
    • (1995) J. Biol. Chem. , vol.270 , pp. 23013-23020
    • Takino, T.1    Sato, H.2    Shinagawa, A.3    Seiki, M.4
  • 51
    • 0344883824 scopus 로고
    • Dissertation, TU München
    • Turk, D. (1992) Dissertation, TU München.
    • (1992)
    • Turk, D.1
  • 52
    • 0029133344 scopus 로고
    • cDNA sequence and mRNA tissue distribution of a novel human MMP with a transmembrane segment
    • Will, H. and Hinzmann, B. (1995) cDNA sequence and mRNA tissue distribution of a novel human MMP with a transmembrane segment. Eur. J. Biochem., 231, 602-608.
    • (1995) Eur. J. Biochem. , vol.231 , pp. 602-608
    • Will, H.1    Hinzmann, B.2
  • 53
    • 0030016342 scopus 로고    scopus 로고
    • The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autocatalytic activation
    • Will, H., Atkinson, S.J., Butler, G.S., Smyth, B. and Murphy, G. (1996) The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autocatalytic activation. J. Biol. Chem., 271, 17119-17123.
    • (1996) J. Biol. Chem. , vol.271 , pp. 17119-17123
    • Will, H.1    Atkinson, S.J.2    Butler, G.S.3    Smyth, B.4    Murphy, G.5
  • 55
    • 0027973352 scopus 로고
    • Solution structure of the active domain of tissue inhibitor of metalloproteinases-2. A new member of the OB fold protein family
    • Williamson, R.A., Martorell, G., Carr, M.D., Murphy, G., Docherty, A.J., Freedman, R.B. and Feeney, J. (1994) Solution structure of the active domain of tissue inhibitor of metalloproteinases-2. A new member of the OB fold protein family. Biochemistry, 33, 11745-11759.
    • (1994) Biochemistry , vol.33 , pp. 11745-11759
    • Williamson, R.A.1    Martorell, G.2    Carr, M.D.3    Murphy, G.4    Docherty, A.J.5    Freedman, R.B.6    Feeney, J.7
  • 56
    • 0030666085 scopus 로고    scopus 로고
    • Mapping the binding site for matrix metalloproteinase on the N-terminal domain of the tissue inhibitor of metalloproteinases-2 by NMR chemical shift perturbation
    • Williamson, R.A., Carr, M.D., Frenkiel, T.A., Feeney, J. and Freedman, R.B. (1997) Mapping the binding site for matrix metalloproteinase on the N-terminal domain of the tissue inhibitor of metalloproteinases-2 by NMR chemical shift perturbation. Biochemistrym, 36, 13882-13889.
    • (1997) Biochemistrym , vol.36 , pp. 13882-13889
    • Williamson, R.A.1    Carr, M.D.2    Frenkiel, T.A.3    Feeney, J.4    Freedman, R.B.5
  • 57
    • 0025847582 scopus 로고
    • Matrix metalloproteinases and their inhibitors in connective tissue remodeling
    • Woessner, J.F., Jr (1991) Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J., 5, 2145-2155.
    • (1991) FASEB J. , vol.5 , pp. 2145-2155
    • Woessner Jr., J.F.1
  • 58
    • 0031984868 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase-2 (TIMP-2) binds to the catalytic domain of the cell surface receptor, membrane type 1-matrix metalloproteinase 1 (MT1-MMP)
    • Zucker, S., Drews, M., Conner, C., Foda, H.D., DeClerck, Y.A., Langley, K.E., Bahou, W.F., Docherty, A.J.P. and Cao, J. (1998) Tissue inhibitor of metalloproteinase-2 (TIMP-2) binds to the catalytic domain of the cell surface receptor, membrane type 1-matrix metalloproteinase 1 (MT1-MMP). J. Biol. Chem., 273, 1216-1222.
    • (1998) J. Biol. Chem. , vol.273 , pp. 1216-1222
    • Zucker, S.1    Drews, M.2    Conner, C.3    Foda, H.D.4    DeClerck, Y.A.5    Langley, K.E.6    Bahou, W.F.7    Docherty, A.J.P.8    Cao, J.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.