The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 2, 2000, Pages 588-592

  Strobl, Stefan ^a,d   Fernandez Catalan, Carlos ^a   Braun, Marianne ^a   Huber, Robert ^a   Masumoto, Hajime ^b   Nakagawa, Kazuhiro ^b   Irie, Akihiro ^b   Sorimachi, Hiroyuki ^b,e   Bourenkow, Gleb ^c   Bartunik, Hans ^c   Suzuki, Koichi ^b   Bode, Wolfram ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b UNIVERSITY OF TOKYO   (Japan)

^c DESY   (Germany)

^d PROTEROS BIOSTRUCTURES GMBH   (Germany)

^e UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALPAIN;

ARTICLE; CALCIUM BINDING; CRYSTAL STRUCTURE; CYTOSKELETON; HUMAN; MEMBRANE BINDING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CALCIUM; CALPAIN; CATALYTIC DOMAIN; COMPUTER GRAPHICS; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; ENZYME ACTIVATION; HUMANS; ISOENZYMES; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; RATS;

ANETHUM GRAVEOLENS;

EID: 12944300453     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.2.588     Document Type: Article

References (35)

1. Sorimachi, H., Ishiura, S. & Suzuki, K. (1997) Biochem. J. 328, 721-732.
2. Carafoli, E. & Molinari, M. (1998) Biochem. Biophys. Res. Commun. 247, 193-203.
3. Richard, I., Roudaut, C., Saenz, A., Pogue, R., Grimbergen, J. E., Anderson, L. V., Beley, C., Cobo, A. M., de Diego, C., Eymard, B., et al. (1999) Am. J. Hum. Genet. 64, 1524-1540.
4. Goll, D. E., Thompson, V. F., Taylor, R. G. & Zalewska, T. (1992) BioEssays 14, 549-556.
5. Johnson, G. V. W. & Guttmann, R. P. (1997) BioEssays 19, 1011-1018.
6. Imajoh, S., Aoki, K., Ohno, S., Emori, Y., Kawasaki, H., Sugihara, H. & Suzuki, K. (1988) Biochemistry 27, 8122-8128.
7. Ohno, S., Emori, Y. & Suzuki, K. (1986) Nucleic Acids Res. 14, 5559.
8. Blanchard, H., Yunge, L., Cygler, M., Kay, C. M., Arthur, J. S. C., Davies, P. L. & Elce, J. S. (1997) Nat. Struct. Biol. 4, 532-538.
9. Lin, G. D., Chattopadhyay, D., Maki, M., Wang, K. K., Carson, M., Jin, L., Yuen, P. W., Takano, E., Hatanaka, M., DeLucas, L. J., et al. (1997) Nat. Struct. Biol. 4, 539-547.
10. Masumoto, H., Nakagawa, K., Irie, S., Sorimachi, H., Suzuki, K., Bourenkov, G. P., Bartunik, H., Fernandez-Catalan, C., Bode, W. & Strobl, S. (2000) Acta Crystallogr. D, in press.
11. Hosfield, C. M., Ye, Q., Arthur, J. S. C., Hegadorn, C., Croall, D. E., Elce, J. S. & Jia, Z. (1999) Acta Crystallogr. D 55, 1481-1486.
12. Masumoto, H., Yoshizawa, T., Sorimachi, H., Nishino, T., Ishiura, S. & Suzuki, K. (1998) J. Biochem. 124, 957-961.
13. Otwinowski, Z. & Minor, W. (1996) Methods Enzymol. 276, 307-326.
14. Collaborative Computing Project 4 (1994) Acta Crystallogr. D 50, 760-763.
15. de la Fortelle, E. & Bricogne, G. (1997) Methods Enzymol. 276, 472-494.
16. Roussel, A. & Cambileau, C. (1989) TURBO FRODO (Centre National de la Recherche Scientifique/Université Aix-Marseille, Marseille, France), Version Open Gl.1.
17. Brünger, A. (1992) X-PLOR Version 3.1; A System for X-Ray Crystallography and NMR. (Yale Univ. Press, New Haven, CT).
18. Kamphuis, I. G., Kalk, K. H., Swarte, B. A. & Drenth, J. (1984) J. Mol. Biol. 179, 233-256.
19. Rizo, J. & Südhoff, T. C. (1998) J. Biol. Chem. 273, 15879-15882.
20. Jones, E. Y., Stuart, D. I. & Walker, N. P. C. (1989) Nature (London) 338, 225-228.
21. Kretsinger, R. H. (1996) Nat. Struct. Biol. 3, 12-15.
22. Suzuki, K. Sorimachi, H., Yoshizawa, T., Kinbara, K. & Ishiura, S. (1995) Biol. Chem. Hoppe-Seyler 376, 523-529.
23. Meador, W. E., Means, A. R. & Quiocho, F. A. (1993) Science 257, 1251-1255.
24. Yoshizawa, T., Sorimachi, H., Tomioka, S., Ishiura, S. & Suzuki, K. (1995) FEBS Lett. 358, 101-103.
25. Michetti, M., Salamino, F., Minafra, R., Melloni, E. & Pontremoli, S. (1997) Biochem. J. 325, 721-726.
26. Brown, N. & Crawford, C. (1993) FEBS Lett. 322, 65-68.
27. Andresen, K., Tom, T. D. & Strand, M. (1991) J. Biol. Chem. 266, 15085-15090.
28. Ono, Y., Shimada, H., Sorimachi, H., Richard, I., Saido, T. C., Beckmann, J. S., Ishiura, S. & Suzuki, K. (1998) J. Biol. Chem. 273, 17073-17078.
29. Takano, E., Ma, H., Yang, H. Q., Maki, M. & Hatanaka, M. (1995) FEBS Lett. 362, 93-97.
30. Shao, X., Fernandez, I., Südhoff, T. C. & Rizo, J. (1998) Biochemistry 37, 16106-16115.
31. Saido, T. C., Shibata, M., Takenawa, T., Murofushi, H. & Suzuki, K. (1992) J. Biol. Chem. 267, 24585-24590.
32. Vilei, E. M., Calderara, S., Anagli, J., Berardi, S., Hitomi, K., Maki, M. & Carafoli, E. (1997) J. Biol. Chem. 272, 25802-25808.
33. Wang, K. K. W., Wang, K. K., Nath, R., Posner, A., Raser, K. J., Buroker-Kilgore, M., Hajimohammadreza, I., Probert, A. W., Jr, Marcoux, F. W., Ye, Q., Takano, E., et al. (1996) Proc. Natl. Acad. Sci. USA 93, 6687-6692.
34. Evans, S. V. (1990) J. Mol. Graph. 11, 134-138.
35. Barton, G. J. (1993) Protein Eng. 6, 37-40.