Cerebral microvascular amyloid β protein deposition induces vascular degeneration and neuroinflammation in transgenic mice expressing human vasculotropic mutant amyloid β precursor protein

American Journal of Pathology

Volumn 167, Issue 2, 2005, Pages 505-515

  Miao, Jianting ^a   Xu, Feng ^a   Davis, Judianne ^a   Otte Höller, Irene ^b   Verbeek, Marcel M ^b   Van Nostrand, William E ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; AMYLOID PRECURSOR PROTEIN; INTERLEUKIN 1;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN BLOOD VESSEL; CELL DENSITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE MODEL; ENCEPHALITIS; GENE MUTATION; MICROGLIA; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE; VASCULAR AMYLOIDOSIS; ANIMAL; APOPTOSIS; BRAIN CIRCULATION; C57BL MOUSE; CEREBELLUM; GENETICS; HUMAN; IMMUNOLOGY; INFLAMMATION; METABOLISM; MICROCIRCULATION; MOUSE; MUTATION; NERVE CELL; PATHOLOGY; TRANSGENE;

AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; APOPTOSIS; ASTROCYTES; CEREBELLUM; CEREBRAL AMYLOID ANGIOPATHY, FAMILIAL; CEREBROVASCULAR CIRCULATION; HUMANS; INFLAMMATION; INTERLEUKIN-1; INTERLEUKIN-6; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROCIRCULATION; MUTATION; NEURONS; TRANSGENES;

EID: 25144486849     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)62993-8     Document Type: Article

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