Structural descriptors of gp120 V3 loop for the prediction of HIV-1 coreceptor usage

PLoS Computational Biology

Volumn 3, Issue 3, 2007, Pages 0555-0564

  Sander, Oliver ^a   Sing, Tobias ^a   Sommer, Ingolf ^a   Low, Andrew J ^b   Cheung, Peter K ^b   Harrigan, P Richard ^b   Lengauer, Thomas ^a   Domingues, Francisco S ^a  

^a MAX PLANCK INSTITUTE FOR INFORMATICS   (Germany)

^b BRITISH COLUMBIA CENTRE FOR EXCELLENCE IN HIV AIDS   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHAINS; DISEASE CONTROL; HEURISTIC METHODS; HYDROGEN BONDS; STRUCTURAL ANALYSIS;

CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; CORECEPTORS; DISEASE PROGRESSION; HYPERVARIABLES; LOOP REGIONS; PREDICTIVE METHODS; SEQUENCE FEATURES; STRUCTURAL DESCRIPTORS; VIRAL GENES;

FORECASTING;

CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS ENVELOPE PROTEIN GP120;

AMINO ACID SEQUENCE; ARTICLE; BIOINFORMATICS; GENETIC ANALYSIS; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROGEN BOND; LEARNING; MONITORING; PHENOTYPE; PREDICTION; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTEIN VARIANT; RECEPTOR BINDING; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS; STATISTICAL MODEL; STRUCTURE ACTIVITY RELATION; VIRUS GENE; CHEMISTRY; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; PHYSIOLOGY; SEQUENCE ALIGNMENT; VIRUS ATTACHMENT; VIRUS ENTRY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SEQUENCE; HIV-1; MOLECULAR SEQUENCE DATA; RECEPTORS, CCR5; RECEPTORS, CXCR4; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS ATTACHMENT; VIRUS INTERNALIZATION;

EID: 34047202703     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.0030058     Document Type: Article

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