A combined structural dynamics approach identifies a putative switch in factor VIIa employed by tissue factor to initiate blood coagulation

Protein Science

Volumn 16, Issue 4, 2007, Pages 671-682

  Olsen, Ole H ^a   Rand, Kasper D ^a   Østergaard, Henrik ^a   Persson, Egon ^a  

^a NOVO NORDISK A S   (Denmark)

Author keywords

Allostery; Coagulation factor VIIa; Deglycosylation; Hydrogen exchange; Molecular mechanics dynamics

Indexed keywords

BLOOD CLOTTING FACTOR 7A; GLYCOPEPTIDASE; THROMBOPLASTIN;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BLOOD CLOTTING; CONFORMATION; CROSS LINKING; DEGLYCOSYLATION; DEUTERIUM HYDROGEN EXCHANGE; MASS SPECTROMETRY; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN STABILITY;

BLOOD COAGULATION; FACTOR VIIA; GLYCOSYLATION; MASS SPECTROMETRY; MODELS, MOLECULAR; PROTEIN CONFORMATION; THROMBOPLASTIN;

EID: 33947720248     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1110/ps.062504907     Document Type: Article

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