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Volumn 40, Issue 11, 2001, Pages 3251-3256
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Substitution of aspartic acid for methionine-306 in factor VIIa abolishes the allosteric linkage between the active site and the binding interface with tissue factor
a
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Author keywords
[No Author keywords available]
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Indexed keywords
ASPARTIC ACID;
BLOOD CLOTTING FACTOR 7A;
METHIONINE;
THROMBOPLASTIN;
ALLOSTERISM;
AMINO ACID SUBSTITUTION;
ANIMAL CELL;
ARTICLE;
BINDING KINETICS;
BINDING SITE;
CATALYSIS;
CELL STRAIN BHK;
DISSOCIATION CONSTANT;
ENZYME ACTIVE SITE;
ENZYME ACTIVITY;
ENZYME BINDING;
ENZYME INHIBITION;
HYDROGEN BOND;
NONHUMAN;
PRIORITY JOURNAL;
PROTEIN PROTEIN INTERACTION;
ALLOSTERIC REGULATION;
AMINO ACID SUBSTITUTION;
ANIMALS;
ASPARTIC ACID;
BINDING SITES;
CATALYSIS;
COMPUTER SIMULATION;
FACTOR VIIA;
HUMANS;
METHIONINE;
MODELS, MOLECULAR;
MUTAGENESIS, SITE-DIRECTED;
PROTEIN BINDING;
RABBITS;
RECOMBINANT PROTEINS;
SOLUBILITY;
THROMBOPLASTIN;
ANIMALIA;
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EID: 0035916953
PISSN: 00062960
EISSN: None
Source Type: Journal
DOI: 10.1021/bi001612z Document Type: Article |
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Times cited : (55)
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References (40)
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