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Volumn 56, Issue 8, 2004, Pages 1143-1160

Folate-receptor-targeted radionuclide imaging agents

Author keywords

Diagnostic imaging; Folate receptor; Nuclear medicine; Radiopharmaceutical

Indexed keywords

CELL CULTURE; CHELATION; DRUG PRODUCTS; RADIOISOTOPES; TUMORS;

EID: 16544383488     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.addr.2004.01.004     Document Type: Article
Times cited : (123)

References (77)
  • 3
    • 0004273134 scopus 로고
    • M. Reivich, & A. Alavi. New York: Alan R. Liss
    • Reivich M., Alavi A. Positron Emission Tomography. 1985;Alan R. Liss, New York.
    • (1985) Positron Emission Tomography
  • 4
    • 0003681214 scopus 로고
    • M.E. Phelps, J.C. Mazziotta, & H.R. Schelbert. New York: Raven Press
    • Phelps M.E., Mazziotta J.C., Schelbert H.R. Positron Emission Tomography and Autoradiography. 1986;Raven Press, New York.
    • (1986) Positron Emission Tomography and Autoradiography
  • 5
    • 0003710961 scopus 로고    scopus 로고
    • G.K. von Schulthess. Philadelphia: Lippincott Williams and Wilkins
    • von Schulthess G.K. Clinical Positron Emission Tomography. 2000;Lippincott Williams and Wilkins, Philadelphia.
    • (2000) Clinical Positron Emission Tomography
  • 7
    • 0027406702 scopus 로고
    • Trophoblast and ovarian cancer antigen LK26. Sensitivity and specificity in immunopathology and molecular identification as a folate-binding protein
    • Garin-Chesa P., Campbell I., Saigo P.E., Lewis J.L. Jr., Old L.J., Rettig W.J. Trophoblast and ovarian cancer antigen LK26. Sensitivity and specificity in immunopathology and molecular identification as a folate-binding protein. Am. J. Pathol. 142:1993;557-567.
    • (1993) Am. J. Pathol. , vol.142 , pp. 557-567
    • Garin-Chesa, P.1    Campbell, I.2    Saigo, P.E.3    Lewis, J.L.Jr.4    Old, L.J.5    Rettig, W.J.6
  • 8
    • 0026019462 scopus 로고
    • Normal tissue reactivity of four anti-tumor monoclonal antibodies of clinical interest
    • Stein R., Goldenberg D.M., Mattes M.J. Normal tissue reactivity of four anti-tumor monoclonal antibodies of clinical interest. Int. J. Cancer. 47:1991;163-169.
    • (1991) Int. J. Cancer , vol.47 , pp. 163-169
    • Stein, R.1    Goldenberg, D.M.2    Mattes, M.J.3
  • 12
    • 0020137031 scopus 로고
    • Renal tubular transport of folic acid and methotrexate in the monkey
    • Williams W.M., Huang K.C. Renal tubular transport of folic acid and methotrexate in the monkey. Am. J. Physiol. 242:1982;F484-F490.
    • (1982) Am. J. Physiol. , vol.242
    • Williams, W.M.1    Huang, K.C.2
  • 13
    • 0021142441 scopus 로고
    • The folate-binding protein of rat kidney
    • Selhub J., Franklin W.A. The folate-binding protein of rat kidney. J. Biol. Chem. 259:1984;6601-6606.
    • (1984) J. Biol. Chem. , vol.259 , pp. 6601-6606
    • Selhub, J.1    Franklin, W.A.2
  • 14
    • 0023215518 scopus 로고
    • Renal folate absorption and the kidney folate binding protein: I. Urinary clearance studies
    • Selhub J., Emmanouel D., Stavropoulos T., Arnold R. Renal folate absorption and the kidney folate binding protein: I. Urinary clearance studies. Am. J. Physiol. 252:1987;F750-F756.
    • (1987) Am. J. Physiol. , vol.252
    • Selhub, J.1    Emmanouel, D.2    Stavropoulos, T.3    Arnold, R.4
  • 15
    • 0023215518 scopus 로고
    • Renal folate adsorption and the kidney folate binding protein: II. Microinfusion studies
    • Selhub J., Nakamura S., Carone F.A. Renal folate adsorption and the kidney folate binding protein: II. Microinfusion studies. Am. J. Physiol. 252:1987;F757-F760.
    • (1987) Am. J. Physiol. , vol.252
    • Selhub, J.1    Nakamura, S.2    Carone, F.A.3
  • 16
    • 0016630298 scopus 로고
    • Identification of a folate binder in hog kidney
    • Kamen B.A., Caston J.D. Identification of a folate binder in hog kidney. J. Biol. Chem. 250:1975;2203-2205.
    • (1975) J. Biol. Chem. , vol.250 , pp. 2203-2205
    • Kamen, B.A.1    Caston, J.D.2
  • 17
    • 0026476410 scopus 로고
    • Cellular localization of the folate receptor: Potential role in drug toxicity and folate homeostasis
    • Weitman S.D., Weinberg A.G., Coney L.R., Zurawski V.R., Jennings D.S., Kamen B.A. Cellular localization of the folate receptor: potential role in drug toxicity and folate homeostasis. Cancer Res. 52:1992;6708-6711.
    • (1992) Cancer Res. , vol.52 , pp. 6708-6711
    • Weitman, S.D.1    Weinberg, A.G.2    Coney, L.R.3    Zurawski, V.R.4    Jennings, D.S.5    Kamen, B.A.6
  • 19
    • 0033563939 scopus 로고    scopus 로고
    • High-affinity folate receptor in human ovary, serous ovarian adenocarcinoma, and ascites: Radioligand binding mechanism, molecular size, ionic properties, hydrophobic domain, and immunoreactivity
    • Holm J., Hansen S.I., Hoier-Madsen M., Birn H., Helkjaer P.-E. High-affinity folate receptor in human ovary, serous ovarian adenocarcinoma, and ascites: radioligand binding mechanism, molecular size, ionic properties, hydrophobic domain, and immunoreactivity. Arch. Biochem. Biophys. 366:1999;183-191.
    • (1999) Arch. Biochem. Biophys. , vol.366 , pp. 183-191
    • Holm, J.1    Hansen, S.I.2    Hoier-Madsen, M.3    Birn, H.4    Helkjaer, P.-E.5
  • 20
    • 0028301752 scopus 로고
    • Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines: Physiologic and clinical implications
    • Ross J.F., Chaudhuri P.K., Ratnam M. Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines: physiologic and clinical implications. Cancer. 73:1994;2432-2443.
    • (1994) Cancer , vol.73 , pp. 2432-2443
    • Ross, J.F.1    Chaudhuri, P.K.2    Ratnam, M.3
  • 21
    • 0032883172 scopus 로고    scopus 로고
    • Expression of folate receptor type α in relation to cell type, malignancy, and differentiation in ovary, uterus and cervix
    • Wu M., Gunning W., Ratnam M. Expression of folate receptor type α in relation to cell type, malignancy, and differentiation in ovary, uterus and cervix. Cancer Epidemiol. Biomark. Prev. 8:1999;775-782.
    • (1999) Cancer Epidemiol. Biomark. Prev. , vol.8 , pp. 775-782
    • Wu, M.1    Gunning, W.2    Ratnam, M.3
  • 22
    • 0028302477 scopus 로고
    • Folate binding protein distribution in normal tissues and biological fluids from ovarian carcinoma patients as detected by the monoclonal antibodies Mov18 and Mov19
    • Mantovani L.T., Miotti S., Menard S., Canevari S., Raspagliesi F., Bottini C., Bottero F., Colnaghi M.I. Folate binding protein distribution in normal tissues and biological fluids from ovarian carcinoma patients as detected by the monoclonal antibodies Mov18 and Mov19. Eur. J. Cancer. 30A:1994;363-369.
    • (1994) Eur. J. Cancer , vol.30 , pp. 363-369
    • Mantovani, L.T.1    Miotti, S.2    Menard, S.3    Canevari, S.4    Raspagliesi, F.5    Bottini, C.6    Bottero, F.7    Colnaghi, M.I.8
  • 24
    • 0033509413 scopus 로고    scopus 로고
    • Selective expression of folate receptor β and its possible role in methotrexate transport in synovial macrophages from patients with rheumatoid arthritis
    • Nakashima-Matsushita N., Homma T., Yu S., Matsuda T., Sunahara N., Nakamura T., Tsukano M., Ratnam M., Matsuyama T. Selective expression of folate receptor β and its possible role in methotrexate transport in synovial macrophages from patients with rheumatoid arthritis. Arthritis Rheum. 42:1999;1609-1616.
    • (1999) Arthritis Rheum. , vol.42 , pp. 1609-1616
    • Nakashima-Matsushita, N.1    Homma, T.2    Yu, S.3    Matsuda, T.4    Sunahara, N.5    Nakamura, T.6    Tsukano, M.7    Ratnam, M.8    Matsuyama, T.9
  • 25
    • 0028986856 scopus 로고
    • Distinguishing between folate receptor-alpha-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells
    • Spinella M.J., Brigle K.E., Sierra E.E., Goldman I.D. Distinguishing between folate receptor-alpha-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells. J. Biol. Chem. 270:1995;7842-7849.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7842-7849
    • Spinella, M.J.1    Brigle, K.E.2    Sierra, E.E.3    Goldman, I.D.4
  • 26
    • 0029565133 scopus 로고
    • A high-affinity soluble folate receptor in fluids of non-neoplastic ovarian cysts: Radioligand binding, molecular size, hydrophobic residue, and immunological properties
    • Holm J., Hansen S.I., Hoier-Madsen M., Helkjaer P.-E., Bzorek M. A high-affinity soluble folate receptor in fluids of non-neoplastic ovarian cysts: radioligand binding, molecular size, hydrophobic residue, and immunological properties. APMIS. 103:1995;862-868.
    • (1995) APMIS , vol.103 , pp. 862-868
    • Holm, J.1    Hansen, S.I.2    Hoier-Madsen, M.3    Helkjaer, P.-E.4    Bzorek, M.5
  • 28
    • 0033574661 scopus 로고    scopus 로고
    • Complete mapping of divergent amino acids responsible for differential ligand binding of folate receptors α and β
    • Maziarz K.M., Monaco H.L., Shen F., Ratnam M. Complete mapping of divergent amino acids responsible for differential ligand binding of folate receptors α and β J. Biol. Chem. 274:1999;11086-11091.
    • (1999) J. Biol. Chem. , vol.274 , pp. 11086-11091
    • Maziarz, K.M.1    Monaco, H.L.2    Shen, F.3    Ratnam, M.4
  • 29
    • 0029022260 scopus 로고
    • Folate receptor type gamma is primarily a secretory protein due to lack of an efficient signal for glycosylphosphatidylinositol modification: Protein characterization and cell type specificity
    • Shen F., Wu M., Ross J.F., Miller D., Ratnam M. Folate receptor type gamma is primarily a secretory protein due to lack of an efficient signal for glycosylphosphatidylinositol modification: protein characterization and cell type specificity. Biochemistry. 34:1995;5660-5665.
    • (1995) Biochemistry , vol.34 , pp. 5660-5665
    • Shen, F.1    Wu, M.2    Ross, J.F.3    Miller, D.4    Ratnam, M.5
  • 30
    • 0342350467 scopus 로고
    • Distribution of the reduced folate carrier (RFC) versus the high affinity membrane folate binding protein (mFBP) in human tumors and tissues
    • Matherly L.H., Wong S.C., Angeles S.M., Taub J.W., Smith G.K. Distribution of the reduced folate carrier (RFC) versus the high affinity membrane folate binding protein (mFBP) in human tumors and tissues. Proc. Am. Assoc. Cancer Res. 35:1994;307.
    • (1994) Proc. Am. Assoc. Cancer Res. , vol.35 , pp. 307
    • Matherly, L.H.1    Wong, S.C.2    Angeles, S.M.3    Taub, J.W.4    Smith, G.K.5
  • 31
    • 0031010021 scopus 로고    scopus 로고
    • Identification of amino acid residues that determine the differential ligand specificities of folate receptors α and β
    • Shen F., Zheng X., Wang J., Ratnam M. Identification of amino acid residues that determine the differential ligand specificities of folate receptors α and β Biochemistry. 36:1997;6157-6163.
    • (1997) Biochemistry , vol.36 , pp. 6157-6163
    • Shen, F.1    Zheng, X.2    Wang, J.3    Ratnam, M.4
  • 32
    • 0032078955 scopus 로고    scopus 로고
    • Structure and regulation of a polymorphic gene encoding folate receptor type γ/γ′
    • Wang H., Ross J.F., Ratnam M. Structure and regulation of a polymorphic gene encoding folate receptor type γ/γ′ Nucleic Acids Res. 26:1998;2132-2142.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 2132-2142
    • Wang, H.1    Ross, J.F.2    Ratnam, M.3
  • 33
    • 0026049546 scopus 로고
    • High-affinity folate binding in human choroid plexus
    • Holm J., Hansen S.I., Hoier-Madsen M., Bostad L. High-affinity folate binding in human choroid plexus. Biochem. J. 280:1991;267-271.
    • (1991) Biochem. J. , vol.280 , pp. 267-271
    • Holm, J.1    Hansen, S.I.2    Hoier-Madsen, M.3    Bostad, L.4
  • 35
    • 0028657627 scopus 로고
    • The NIH consensus conference on ovarian cancer: Screening, treatment, and follow-up
    • Trimble E.L. The NIH consensus conference on ovarian cancer: screening, treatment, and follow-up. Gynecol. Oncol. 55:1994;S1-S3.
    • (1994) Gynecol. Oncol. , vol.55
    • Trimble, E.L.1
  • 36
    • 0030946330 scopus 로고    scopus 로고
    • Overview by an oncologist: What are the imaging needs of the oncologist and oncological surgeon?
    • Gucalp R., Dutcher J., Wiernik P.H. Overview by an oncologist: what are the imaging needs of the oncologist and oncological surgeon? Semin. Nucl. Med. 27:1997;3-9.
    • (1997) Semin. Nucl. Med. , vol.27 , pp. 3-9
    • Gucalp, R.1    Dutcher, J.2    Wiernik, P.H.3
  • 37
    • 0031944910 scopus 로고    scopus 로고
    • Expression of folate binding protein as a prognostic factor for response to platinum-containing chemotherapy and survival in human ovarian cancer
    • Toffoli G., Russo A., Gallo A., Cernigoi C., Miotti S., Sorio R., Tumolo S., Boiocchi M. Expression of folate binding protein as a prognostic factor for response to platinum-containing chemotherapy and survival in human ovarian cancer. Int. J. Cancer (Pred. Oncol.). 79:1998;121-126.
    • (1998) Int. J. Cancer (Pred. Oncol.) , vol.79 , pp. 121-126
    • Toffoli, G.1    Russo, A.2    Gallo, A.3    Cernigoi, C.4    Miotti, S.5    Sorio, R.6    Tumolo, S.7    Boiocchi, M.8
  • 40
    • 0026564990 scopus 로고
    • Experimental and clinical analysis of the characteristics of a chimeric monoclonal antibody, Mov18, reactive with an ovarian cancer-associated antigen
    • Molthoff C.F., Buist M.R., Kenemans P., Pinedo H.M., Boven E. Experimental and clinical analysis of the characteristics of a chimeric monoclonal antibody, Mov18, reactive with an ovarian cancer-associated antigen. J. Nucl. Med. 33:1992;2000-2005.
    • (1992) J. Nucl. Med. , vol.33 , pp. 2000-2005
    • Molthoff, C.F.1    Buist, M.R.2    Kenemans, P.3    Pinedo, H.M.4    Boven, E.5
  • 43
    • 0034789169 scopus 로고    scopus 로고
    • Radioimmunoscintigraphy in patients with ovarian cancer
    • Kalofonos H.P., Karamouzis M.V., Epenetos A.A. Radioimmunoscintigraphy in patients with ovarian cancer. Acta Oncol. 40:2001;549-557.
    • (2001) Acta Oncol. , vol.40 , pp. 549-557
    • Kalofonos, H.P.1    Karamouzis, M.V.2    Epenetos, A.A.3
  • 45
    • 0030163022 scopus 로고    scopus 로고
    • Tumor-selective radiopharmaceutical targeting via receptor-mediated endocytosis of gallium-67-deferoxamine-folate
    • Mathias C.J., Wang S., Lee R.J., Water D.J., Low P.S., Green M.A. Tumor-selective radiopharmaceutical targeting via receptor-mediated endocytosis of gallium-67-deferoxamine-folate. J. Nucl. Med. 37:1996;1003-1008.
    • (1996) J. Nucl. Med. , vol.37 , pp. 1003-1008
    • Mathias, C.J.1    Wang, S.2    Lee, R.J.3    Water, D.J.4    Low, P.S.5    Green, M.A.6
  • 48
    • 0023683407 scopus 로고
    • Delivery of folates to the cytoplasm of MA104 cells is mediated by a surface membrane receptor that recycles
    • Kamen B.A., Wang M.T., Streckfuss A.J., Peryea X., Anderson R.G.W. Delivery of folates to the cytoplasm of MA104 cells is mediated by a surface membrane receptor that recycles. J. Biol. Chem. 263:1988;13602-13609.
    • (1988) J. Biol. Chem. , vol.263 , pp. 13602-13609
    • Kamen, B.A.1    Wang, M.T.2    Streckfuss, A.J.3    Peryea, X.4    Anderson, R.G.W.5
  • 49
    • 0022358451 scopus 로고
    • Study of the role of a particulate folate-binding protein in the uptake of 5-methyltetrahydrofolate
    • Antony A.C., Kane M.A., Portillo R.M., Elwood P.C., Kolhouse J.F. Study of the role of a particulate folate-binding protein in the uptake of 5-methyltetrahydrofolate. J. Biol. Chem. 260:1985;14911-14917.
    • (1985) J. Biol. Chem. , vol.260 , pp. 14911-14917
    • Antony, A.C.1    Kane, M.A.2    Portillo, R.M.3    Elwood, P.C.4    Kolhouse, J.F.5
  • 50
    • 0025951931 scopus 로고
    • Delivery of macromolecules into living cells: A method that exploits folate receptor endocytosis
    • Leamon C.P., Low P.S. Delivery of macromolecules into living cells: a method that exploits folate receptor endocytosis. Proc. Natl. Acad. Sci. U. S. A. 88:1991;5572-5576.
    • (1991) Proc. Natl. Acad. Sci. U. S. A. , vol.88 , pp. 5572-5576
    • Leamon, C.P.1    Low, P.S.2
  • 53
    • 0030662090 scopus 로고    scopus 로고
    • Efficient syntheses of pyrofolic acid and pteroyl azide, reagents for the production of carboxyl-differentiated derivatives of folic acid
    • Luo J., Smith M.D., Lantrip D.A., Wang S., Fuchs P.L. Efficient syntheses of pyrofolic acid and pteroyl azide, reagents for the production of carboxyl-differentiated derivatives of folic acid. J. Am. Chem. Soc. 119:1997;10004-10013.
    • (1997) J. Am. Chem. Soc. , vol.119 , pp. 10004-10013
    • Luo, J.1    Smith, M.D.2    Lantrip, D.A.3    Wang, S.4    Fuchs, P.L.5
  • 54
    • 0031658693 scopus 로고    scopus 로고
    • Indium-111-DTPA-Folate as a potential folate-receptor-targeted radiopharmaceutical
    • Mathias C.J., Wang S., Waters D.J., Turek J.J., Low P.S., Green M.A. Indium-111-DTPA-Folate as a potential folate-receptor-targeted radiopharmaceutical. J. Nucl. Med. 39:1998;1579-1585.
    • (1998) J. Nucl. Med. , vol.39 , pp. 1579-1585
    • Mathias, C.J.1    Wang, S.2    Waters, D.J.3    Turek, J.J.4    Low, P.S.5    Green, M.A.6
  • 55
    • 0031871186 scopus 로고    scopus 로고
    • 111In]In-DTPA-folate, a folate-receptor-targeted radiopharmaceutical
    • 111In]In-DTPA-folate, a folate-receptor-targeted radiopharmaceutical. Nucl. Med. Biol. 25:1998;585-587.
    • (1998) Nucl. Med. Biol. , vol.25 , pp. 585-587
    • Mathias, C.J.1    Green, M.A.2
  • 56
    • 16544383298 scopus 로고    scopus 로고
    • Alternative kit formulations for compounding of In-111-DTPA-folate (Folatescan)
    • Mathias C.J., Green M.A. Alternative kit formulations for compounding of In-111-DTPA-folate (Folatescan). J. Nucl. Med. 41:2000;S1113.
    • (2000) J. Nucl. Med. , vol.41 , pp. 1113
    • Mathias, C.J.1    Green, M.A.2
  • 57
    • 0344435471 scopus 로고    scopus 로고
    • Indium-111-labeled indium(III)-DTPA-folate as a radiopharmaceutical for targeting tumor-associated folate receptors: The effect of tumor size on targeting selectivity and radiochemical analysis of excreted tracer
    • Mathias C.J., Waters D.J., Wang S., Low P.S., Green M.A. Indium-111-labeled indium(III)-DTPA-folate as a radiopharmaceutical for targeting tumor-associated folate receptors: the effect of tumor size on targeting selectivity and radiochemical analysis of excreted tracer. J. Labelled Compd. Radiopharm. 40:1997;365-367.
    • (1997) J. Labelled Compd. Radiopharm. , vol.40 , pp. 365-367
    • Mathias, C.J.1    Waters, D.J.2    Wang, S.3    Low, P.S.4    Green, M.A.5
  • 60
    • 0033625094 scopus 로고    scopus 로고
    • 99mTc]DTPA-Folate and its evaluation as a folate-receptor-targeted radiopharmaceutical
    • 99mTc]DTPA-Folate and its evaluation as a folate-receptor-targeted radiopharmaceutical. Bioconjug. Chem. 11:2000;253-257.
    • (2000) Bioconjug. Chem. , vol.11 , pp. 253-257
    • Mathias, C.J.1    Hubers, D.2    Low, P.S.3    Green, M.A.4
  • 63
    • 0024409462 scopus 로고
    • The molecular structure of indium-DTPA
    • Maecke H.R., Riesen A., Ritter W. The molecular structure of indium-DTPA. J. Nucl. Med. 30:1989;1235-1239.
    • (1989) J. Nucl. Med. , vol.30 , pp. 1235-1239
    • Maecke, H.R.1    Riesen, A.2    Ritter, W.3
  • 65
    • 0022968394 scopus 로고
    • Synthesis of 1-(p-isothiocyanatobenzyl) derivatives of DTPA and EDTA. Antibody labeling and tumor-imaging studies
    • Brechbiel M.W., Gansow O.A., Atcher R.W., Schlom J., Esteban J., Simpson D.E., Colcher D. Synthesis of 1-(p-isothiocyanatobenzyl) derivatives of DTPA and EDTA. Antibody labeling and tumor-imaging studies. Inorg. Chem. 25:1986;2772-2781.
    • (1986) Inorg. Chem. , vol.25 , pp. 2772-2781
    • Brechbiel, M.W.1    Gansow, O.A.2    Atcher, R.W.3    Schlom, J.4    Esteban, J.5    Simpson, D.E.6    Colcher, D.7
  • 68
    • 0344401038 scopus 로고
    • Receptor-mediated folate accumulation is regulated by the cellular folate content
    • Kamen B.A., Capdevila A. Receptor-mediated folate accumulation is regulated by the cellular folate content. Proc. Natl. Acad. Sci. U. S. A. 83:1986;5983-5987.
    • (1986) Proc. Natl. Acad. Sci. U. S. A. , vol.83 , pp. 5983-5987
    • Kamen, B.A.1    Capdevila, A.2
  • 72
    • 0008883289 scopus 로고    scopus 로고
    • 99mTc Labeled small peptides as diagnostic radiopharmaceuticals
    • 99mTc Labeled small peptides as diagnostic radiopharmaceuticals. Chem. Rev. 99:1999;2235-2268.
    • (1999) Chem. Rev. , vol.99 , pp. 2235-2268
    • Liu, S.1    Edwards, D.S.2
  • 74
    • 0032588840 scopus 로고    scopus 로고
    • 99mTc-HYNIC-folate: A novel receptor-based targeted radiopharmaceutical for tumor imaging
    • 99mTc-HYNIC-folate: a novel receptor-based targeted radiopharmaceutical for tumor imaging. J. Nucl. Med. 40:1999;1563-1569.
    • (1999) J. Nucl. Med. , vol.40 , pp. 1563-1569
    • Guo, W.1    Hinkle, G.H.2    Lee, R.J.3
  • 77
    • 0032773127 scopus 로고    scopus 로고
    • Synthesis and evaluation of folate-bis(thiosemicarbazone) and folate-CYCLAM conjugates for possible use as folate-receptor-targeted copper radiopharmaceuticals
    • Ke C.-Y., Mathias C.J., Yang Z.-F., Luo J., Low P.S., Waters D.J., Green M.A. Synthesis and evaluation of folate-bis(thiosemicarbazone) and folate-CYCLAM conjugates for possible use as folate-receptor-targeted copper radiopharmaceuticals. J. Labelled Compd. Radiopharm. 42:1999;S821-S823.
    • (1999) J. Labelled Compd. Radiopharm. , vol.42
    • Ke, C.-Y.1    Mathias, C.J.2    Yang, Z.-F.3    Luo, J.4    Low, P.S.5    Waters, D.J.6    Green, M.A.7


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