Design and synthesis of [111In]DTPA-folate for use as a tumor-targeted radiopharmaceutical

Bioconjugate Chemistry

Volumn 8, Issue 5, 1997, Pages 673-679

  Wang, Susan ^a   Luo, Jin ^a   Lantrip, Douglas A ^a   Waters, David J ^b   Mathias, Carla J ^c   Green, Mark A ^c   Fuchs, Philip L ^a   Low, Philip S ^a  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

^c PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; COLUMN CHROMATOGRAPHY; CYTOLOGY; DISEASES; MAMMALS; MASS SPECTROMETRY; NUCLEAR MEDICINE; ORGANIC ACIDS; TUMORS;

CARBOXYL GROUPS; DEFEROXAMINE; DIETHYLENETRIAMINE PENTA-ACETIC ACIDS; FOLATE RECEPTOR; FOLATES; FOLIC ACIDS; IMAGING AGENT; IN-VIVO; METAL CHELATE; POTENTIAL IMAGING;

CHELATION;

MUS MUSCULUS;

CELL SURFACE RECEPTOR; CHELATING AGENT; DIAGNOSTIC AGENT; DRUG DERIVATIVE; DTPA FOLATE; FOLIC ACID; INDIUM; PENTETIC ACID; RADIOPHARMACEUTICAL AGENT;

ANIMAL; ARTICLE; BIOTRANSFORMATION; CELL CULTURE; CELL STRAIN KB; CHEMISTRY; DRUG DESIGN; EXPERIMENTAL NEOPLASM; HUMAN; MALE; METABOLISM; MOUSE; NUDE MOUSE; RAT; SCINTISCANNING; SPRAGUE DAWLEY RAT; SYNTHESIS; TISSUE DISTRIBUTION; WHOLE BODY COUNTING;

ANIMALS; BIOTRANSFORMATION; CELLS, CULTURED; CHELATING AGENTS; DRUG DESIGN; FOLIC ACID; HUMANS; INDIUM RADIOISOTOPES; KB CELLS; MALE; MICE; MICE, NUDE; NEOPLASMS, EXPERIMENTAL; PENTETIC ACID; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CELL SURFACE; TISSUE DISTRIBUTION; WHOLE-BODY COUNTING;

EID: 0030611096     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc9701297     Document Type: Article

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