-
1
-
-
9644278048
-
Ovarian cancer: state of the art and future directions
-
Awada A., and Klastersky J. Ovarian cancer: state of the art and future directions. Eur. J. Gynaecol. Oncol. 25 (2004) 673-676
-
(2004)
Eur. J. Gynaecol. Oncol.
, vol.25
, pp. 673-676
-
-
Awada, A.1
Klastersky, J.2
-
2
-
-
19744368302
-
Cancer of the ovary
-
Cannistra S.A. Cancer of the ovary. N. Engl. J. Med. 351 (2004) 2519-2529
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 2519-2529
-
-
Cannistra, S.A.1
-
3
-
-
18844432114
-
Treatment goals in ovarian cancer
-
Ozols R.F. Treatment goals in ovarian cancer. Int. J. Gynecol. Cancer 15 Suppl. 1 (2005) 3-11
-
(2005)
Int. J. Gynecol. Cancer
, vol.15
, Issue.SUPPL. 1
, pp. 3-11
-
-
Ozols, R.F.1
-
4
-
-
0025775323
-
Acquired cisplatin resistance in human ovarian cancer cells is associated with enhanced repair of cisplatin-DNA lesions and reduced drug accumulation
-
Parker R.J., Eastman A., Bostick-Bruton F., and Reed E. Acquired cisplatin resistance in human ovarian cancer cells is associated with enhanced repair of cisplatin-DNA lesions and reduced drug accumulation. J. Clin. Invest. 87 (1991) 772-777
-
(1991)
J. Clin. Invest.
, vol.87
, pp. 772-777
-
-
Parker, R.J.1
Eastman, A.2
Bostick-Bruton, F.3
Reed, E.4
-
5
-
-
0023875417
-
cis-Diamminedichloroplatinum(II) accumulation in sensitive and resistant human ovarian carcinoma cells
-
Andrews P.A., Velury S., Mann S.C., and Howell S.B. cis-Diamminedichloroplatinum(II) accumulation in sensitive and resistant human ovarian carcinoma cells. Cancer Res. 48 (1988) 68-73
-
(1988)
Cancer Res.
, vol.48
, pp. 68-73
-
-
Andrews, P.A.1
Velury, S.2
Mann, S.C.3
Howell, S.B.4
-
6
-
-
0026594392
-
High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis
-
Godwin A.K., Meister A., O'Dwyer P.J., Huang C.S., Hamilton T.C., and Anderson M.E. High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis. Proc. Natl. Acad. Sci. U. S. A. 89 (1992) 3070-3074
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 3070-3074
-
-
Godwin, A.K.1
Meister, A.2
O'Dwyer, P.J.3
Huang, C.S.4
Hamilton, T.C.5
Anderson, M.E.6
-
7
-
-
0031020450
-
Increased platinum-DNA damage tolerance is associated with cisplatin resistance and cross-resistance to various chemotherapeutic agents in unrelated human ovarian cancer cell lines
-
Johnson S.W., Laub P.B., Beesley J.S., Ozols R.F., and Hamilton T.C. Increased platinum-DNA damage tolerance is associated with cisplatin resistance and cross-resistance to various chemotherapeutic agents in unrelated human ovarian cancer cell lines. Cancer Res. 57 (1997) 850-856
-
(1997)
Cancer Res.
, vol.57
, pp. 850-856
-
-
Johnson, S.W.1
Laub, P.B.2
Beesley, J.S.3
Ozols, R.F.4
Hamilton, T.C.5
-
8
-
-
0030941622
-
Drug-induced DNA hypermethylation: a potential mediator of acquired drug resistance during cancer chemotherapy
-
Nyce J.W. Drug-induced DNA hypermethylation: a potential mediator of acquired drug resistance during cancer chemotherapy. Mutat. Res. 386 (1997) 153-161
-
(1997)
Mutat. Res.
, vol.386
, pp. 153-161
-
-
Nyce, J.W.1
-
9
-
-
18244431930
-
Mechanisms of cytotoxicity caused by antitumour drugs
-
Spec. No:553-561
-
Hickman J.A., Beere H.M., Wood A.C., Waters C.M., and Parmar R. Mechanisms of cytotoxicity caused by antitumour drugs. Toxicol. Lett. (1992) 64-65 Spec. No:553-561
-
(1992)
Toxicol. Lett.
, pp. 64-65
-
-
Hickman, J.A.1
Beere, H.M.2
Wood, A.C.3
Waters, C.M.4
Parmar, R.5
-
10
-
-
0028025563
-
Apoptosis in cancer therapy: crossing the threshold
-
Fisher D.E. Apoptosis in cancer therapy: crossing the threshold. Cell 78 (1994) 539-542
-
(1994)
Cell
, vol.78
, pp. 539-542
-
-
Fisher, D.E.1
-
11
-
-
0029058436
-
Cisplatin resistance in a murine leukemia cell line is associated with a defective apoptotic process
-
Segal-Bendirdjian E., and Jacquemin-Sablon A. Cisplatin resistance in a murine leukemia cell line is associated with a defective apoptotic process. Exp. Cell Res. 218 (1995) 201-212
-
(1995)
Exp. Cell Res.
, vol.218
, pp. 201-212
-
-
Segal-Bendirdjian, E.1
Jacquemin-Sablon, A.2
-
12
-
-
0345256652
-
Cisplatin: mode of cytotoxic action and molecular basis of resistance
-
Siddik Z.H. Cisplatin: mode of cytotoxic action and molecular basis of resistance. Oncogene 22 (2003) 7265-7279
-
(2003)
Oncogene
, vol.22
, pp. 7265-7279
-
-
Siddik, Z.H.1
-
13
-
-
18244379333
-
Cellular processing of platinum anticancer drugs
-
Wang D., and Lippard S.J. Cellular processing of platinum anticancer drugs. Nat. Rev., Drug Discov. 4 (2005) 307-320
-
(2005)
Nat. Rev., Drug Discov.
, vol.4
, pp. 307-320
-
-
Wang, D.1
Lippard, S.J.2
-
15
-
-
0035434459
-
Resistance to cytotoxic agents
-
Robert J. Resistance to cytotoxic agents. Curr. Opin. Pharmacol. 1 (2001) 353-357
-
(2001)
Curr. Opin. Pharmacol.
, vol.1
, pp. 353-357
-
-
Robert, J.1
-
16
-
-
33645516362
-
Akt-mediated cisplatin resistance in ovarian cancer: modulation of p53 action on caspase-dependent mitochondrial death pathway
-
Yang X., Fraser M., Moll U.M., Basak A., and Tsang B.K. Akt-mediated cisplatin resistance in ovarian cancer: modulation of p53 action on caspase-dependent mitochondrial death pathway. Cancer Res. 66 (2006) 3126-3136
-
(2006)
Cancer Res.
, vol.66
, pp. 3126-3136
-
-
Yang, X.1
Fraser, M.2
Moll, U.M.3
Basak, A.4
Tsang, B.K.5
-
17
-
-
15544369937
-
Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line
-
Lee S., Choi E.J., Jin C., and Kim D.H. Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line. Gynecol. Oncol. 97 (2005) 26-34
-
(2005)
Gynecol. Oncol.
, vol.97
, pp. 26-34
-
-
Lee, S.1
Choi, E.J.2
Jin, C.3
Kim, D.H.4
-
18
-
-
0036968347
-
Activation of the PI3K/Akt pathway and chemotherapeutic resistance
-
West K.A., Castillo S.S., and Dennis P.A. Activation of the PI3K/Akt pathway and chemotherapeutic resistance. Drug Resist. Updat. 5 (2002) 234-248
-
(2002)
Drug Resist. Updat.
, vol.5
, pp. 234-248
-
-
West, K.A.1
Castillo, S.S.2
Dennis, P.A.3
-
19
-
-
0842284092
-
Cisplatin resistance in an ovarian carcinoma is associated with a defect in programmed cell death control through XIAP regulation
-
Mansouri A., Zhang Q., Ridgway L.D., Tian L., and Claret F.X. Cisplatin resistance in an ovarian carcinoma is associated with a defect in programmed cell death control through XIAP regulation. Oncol. Res. 13 (2003) 399-404
-
(2003)
Oncol. Res.
, vol.13
, pp. 399-404
-
-
Mansouri, A.1
Zhang, Q.2
Ridgway, L.D.3
Tian, L.4
Claret, F.X.5
-
20
-
-
0036619301
-
Role of X-linked inhibitor of apoptosis protein in chemoresistance in ovarian cancer: possible involvement of the phosphoinositide-3 kinase/Akt pathway
-
Cheng J.Q., Jiang X., Fraser M., Li M., Dan H.C., Sun M., et al. Role of X-linked inhibitor of apoptosis protein in chemoresistance in ovarian cancer: possible involvement of the phosphoinositide-3 kinase/Akt pathway. Drug Resist. Updat. 5 (2002) 131-146
-
(2002)
Drug Resist. Updat.
, vol.5
, pp. 131-146
-
-
Cheng, J.Q.1
Jiang, X.2
Fraser, M.3
Li, M.4
Dan, H.C.5
Sun, M.6
-
21
-
-
0027945731
-
The Bcl-2 family of proteins: regulators of cell death and survival
-
Nunez G., and Clarke M.F. The Bcl-2 family of proteins: regulators of cell death and survival. Trends Cell Biol. 4 (1994) 399-403
-
(1994)
Trends Cell Biol.
, vol.4
, pp. 399-403
-
-
Nunez, G.1
Clarke, M.F.2
-
22
-
-
0030046508
-
Life, death, and the pursuit of apoptosis
-
White E. Life, death, and the pursuit of apoptosis. Genes Dev. 10 (1996) 1-15
-
(1996)
Genes Dev.
, vol.10
, pp. 1-15
-
-
White, E.1
-
23
-
-
0036716281
-
The Bcl2 family: regulators of the cellular life-or-death switch
-
Cory S., and Adams J.M. The Bcl2 family: regulators of the cellular life-or-death switch. Nat. Rev., Cancer 2 (2002) 647-656
-
(2002)
Nat. Rev., Cancer
, vol.2
, pp. 647-656
-
-
Cory, S.1
Adams, J.M.2
-
24
-
-
0033119372
-
BCL-2 gene family and the regulation of programmed cell death
-
Korsmeyer S.J. BCL-2 gene family and the regulation of programmed cell death. Cancer Res. 59 (1999) 1693s-1700s
-
(1999)
Cancer Res.
, vol.59
-
-
Korsmeyer, S.J.1
-
25
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner M.O. The biochemistry of apoptosis. Nature 407 (2000) 770-776
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
26
-
-
29344454248
-
Regulation of the mitochondrial apoptosis-induced channel, MAC, by BCL-2 family proteins
-
Dejean L.M., Martinez-Caballero S., Manon S., and Kinnally K.W. Regulation of the mitochondrial apoptosis-induced channel, MAC, by BCL-2 family proteins. Biochim. Biophys. Acta 1762 (2006) 191-201
-
(2006)
Biochim. Biophys. Acta
, vol.1762
, pp. 191-201
-
-
Dejean, L.M.1
Martinez-Caballero, S.2
Manon, S.3
Kinnally, K.W.4
-
28
-
-
1442286330
-
The role of Bcl-2 family members in tumorigenesis
-
Kirkin V., Joos S., and Zornig M. The role of Bcl-2 family members in tumorigenesis. Biochim. Biophys. Acta 1644 (2004) 229-249
-
(2004)
Biochim. Biophys. Acta
, vol.1644
, pp. 229-249
-
-
Kirkin, V.1
Joos, S.2
Zornig, M.3
-
29
-
-
0028982183
-
Expression of bcl-xL can confer a multidrug resistance phenotype
-
Minn A.J., Rudin C.M., Boise L.H., and Thompson C.B. Expression of bcl-xL can confer a multidrug resistance phenotype. Blood 86 (1995) 1903-1910
-
(1995)
Blood
, vol.86
, pp. 1903-1910
-
-
Minn, A.J.1
Rudin, C.M.2
Boise, L.H.3
Thompson, C.B.4
-
30
-
-
0028979439
-
Bcl-xL is expressed in neuroblastoma cells and modulates chemotherapy-induced apoptosis
-
Dole M.G., Jasty R., Cooper M.J., Thompson C.B., Nunez G., and Castle V.P. Bcl-xL is expressed in neuroblastoma cells and modulates chemotherapy-induced apoptosis. Cancer Res. 55 (1995) 2576-2582
-
(1995)
Cancer Res.
, vol.55
, pp. 2576-2582
-
-
Dole, M.G.1
Jasty, R.2
Cooper, M.J.3
Thompson, C.B.4
Nunez, G.5
Castle, V.P.6
-
31
-
-
0030795866
-
Bcl-2 and Bcl-XL can differentially block chemotherapy-induced cell death
-
Simonian P.L., Grillot D.A., and Nunez G. Bcl-2 and Bcl-XL can differentially block chemotherapy-induced cell death. Blood 90 (1997) 1208-1216
-
(1997)
Blood
, vol.90
, pp. 1208-1216
-
-
Simonian, P.L.1
Grillot, D.A.2
Nunez, G.3
-
32
-
-
0031045967
-
bcl-2 over-expression delays radiation-induced apoptosis without affecting the clonogenic survival of human prostate cancer cells
-
Kyprianou N., King E.D., Bradbury D., and Rhee J.G. bcl-2 over-expression delays radiation-induced apoptosis without affecting the clonogenic survival of human prostate cancer cells. Int. J. Cancer 70 (1997) 341-348
-
(1997)
Int. J. Cancer
, vol.70
, pp. 341-348
-
-
Kyprianou, N.1
King, E.D.2
Bradbury, D.3
Rhee, J.G.4
-
33
-
-
0034048187
-
Effects of Bcl-2 and Bcl-XL protein levels on chemoresistance of hepatoblastoma HepG2 cell line
-
Luo D., Cheng S.C., Xie H., and Xie Y. Effects of Bcl-2 and Bcl-XL protein levels on chemoresistance of hepatoblastoma HepG2 cell line. Biochem. Cell. Biol. 78 (2000) 119-126
-
(2000)
Biochem. Cell. Biol.
, vol.78
, pp. 119-126
-
-
Luo, D.1
Cheng, S.C.2
Xie, H.3
Xie, Y.4
-
34
-
-
0034326272
-
Bcl-xL in prostate cancer cells: effects of overexpression and down-regulation on chemosensitivity
-
Lebedeva I., Rando R., Ojwang J., Cossum P., and Stein C.A. Bcl-xL in prostate cancer cells: effects of overexpression and down-regulation on chemosensitivity. Cancer Res. 60 (2000) 6052-6060
-
(2000)
Cancer Res.
, vol.60
, pp. 6052-6060
-
-
Lebedeva, I.1
Rando, R.2
Ojwang, J.3
Cossum, P.4
Stein, C.A.5
-
35
-
-
0036040031
-
The anti-apoptotic genes Bcl-X(L) and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells
-
Konopleva M., Zhao S., Hu W., Jiang S., Snell V., Weidner D., et al. The anti-apoptotic genes Bcl-X(L) and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells. Br. J. Haematol. 118 (2002) 521-534
-
(2002)
Br. J. Haematol.
, vol.118
, pp. 521-534
-
-
Konopleva, M.1
Zhao, S.2
Hu, W.3
Jiang, S.4
Snell, V.5
Weidner, D.6
-
36
-
-
0034327411
-
An informatics approach identifying markers of chemosensitivity in human cancer cell lines
-
Amundson S.A., Myers T.G., Scudiero D., Kitada S., Reed J.C., and Fornace Jr. A.J. An informatics approach identifying markers of chemosensitivity in human cancer cell lines. Cancer Res. 60 (2000) 6101-6110
-
(2000)
Cancer Res.
, vol.60
, pp. 6101-6110
-
-
Amundson, S.A.1
Myers, T.G.2
Scudiero, D.3
Kitada, S.4
Reed, J.C.5
Fornace Jr., A.J.6
-
37
-
-
0031595523
-
Bcl-xL is expressed in ovarian carcinoma and modulates chemotherapy-induced apoptosis
-
Liu J.R., Fletcher B., Page C., Hu C., Nunez G., and Baker V. Bcl-xL is expressed in ovarian carcinoma and modulates chemotherapy-induced apoptosis. Gynecol. Oncol. 70 (1998) 398-403
-
(1998)
Gynecol. Oncol.
, vol.70
, pp. 398-403
-
-
Liu, J.R.1
Fletcher, B.2
Page, C.3
Hu, C.4
Nunez, G.5
Baker, V.6
-
38
-
-
0031939573
-
bcl-2, bax, bcl-XL, and bcl-XS expression in normal and neoplastic ovarian tissues
-
Marone M., Scambia G., Mozzetti S., Ferrandina G., Iacovella S., De Pasqua A., et al. bcl-2, bax, bcl-XL, and bcl-XS expression in normal and neoplastic ovarian tissues. Clin. Cancer Res. 4 (1998) 517-524
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 517-524
-
-
Marone, M.1
Scambia, G.2
Mozzetti, S.3
Ferrandina, G.4
Iacovella, S.5
De Pasqua, A.6
-
39
-
-
0034669625
-
Expression of apoptosis-related proteins is an independent determinant of patient prognosis in advanced ovarian cancer
-
Baekelandt M., Holm R., Nesland J.M., Trope C.G., and Kristensen G.B. Expression of apoptosis-related proteins is an independent determinant of patient prognosis in advanced ovarian cancer. J. Clin. Oncol. 18 (2000) 3775-3781
-
(2000)
J. Clin. Oncol.
, vol.18
, pp. 3775-3781
-
-
Baekelandt, M.1
Holm, R.2
Nesland, J.M.3
Trope, C.G.4
Kristensen, G.B.5
-
40
-
-
12344266609
-
Expression of Bcl-xL in ovarian carcinoma is associated with chemoresistance and recurrent disease
-
Williams J., Lucas P.C., Griffith K.A., Choi M., Fogoros S., Hu Y.Y., et al. Expression of Bcl-xL in ovarian carcinoma is associated with chemoresistance and recurrent disease. Gynecol. Oncol. 96 (2005) 287-295
-
(2005)
Gynecol. Oncol.
, vol.96
, pp. 287-295
-
-
Williams, J.1
Lucas, P.C.2
Griffith, K.A.3
Choi, M.4
Fogoros, S.5
Hu, Y.Y.6
-
41
-
-
0032835310
-
Increased bcl-2 expression is associated with primary resistance to chemotherapy in human epithelial ovarian cancer
-
Kassim S.K., Ali H.S., Sallam M.M., Fayed S.T., Seada L.S., abd-Elkawy E., et al. Increased bcl-2 expression is associated with primary resistance to chemotherapy in human epithelial ovarian cancer. Clin. Biochem. 32 (1999) 333-338
-
(1999)
Clin. Biochem.
, vol.32
, pp. 333-338
-
-
Kassim, S.K.1
Ali, H.S.2
Sallam, M.M.3
Fayed, S.T.4
Seada, L.S.5
abd-Elkawy, E.6
-
42
-
-
30444435540
-
Bcl-X(L) is functionally non-equivalent for the regulation of growth and survival in human ovarian cancer cells
-
Dodier P., and Piche A. Bcl-X(L) is functionally non-equivalent for the regulation of growth and survival in human ovarian cancer cells. Gynecol. Oncol. 100 (2006) 254-263
-
(2006)
Gynecol. Oncol.
, vol.100
, pp. 254-263
-
-
Dodier, P.1
Piche, A.2
-
43
-
-
0033965759
-
BCL-2 family protein expression and platinum drug resistance in ovarian carcinoma
-
Beale P.J., Rogers P., Boxall F., Sharp S.Y., and Kelland L.R. BCL-2 family protein expression and platinum drug resistance in ovarian carcinoma. Br. J. Cancer 82 (2000) 436-440
-
(2000)
Br. J. Cancer
, vol.82
, pp. 436-440
-
-
Beale, P.J.1
Rogers, P.2
Boxall, F.3
Sharp, S.Y.4
Kelland, L.R.5
-
44
-
-
0031725607
-
Acquisition of chemoresistance in a human ovarian carcinoma cell is linked to a defect in cell cycle control
-
Poulain L., Lincet H., Duigou F., Deslandes E., Sichel F., Gauduchon P., et al. Acquisition of chemoresistance in a human ovarian carcinoma cell is linked to a defect in cell cycle control. Int. J. Cancer 78 (1998) 454-463
-
(1998)
Int. J. Cancer
, vol.78
, pp. 454-463
-
-
Poulain, L.1
Lincet, H.2
Duigou, F.3
Deslandes, E.4
Sichel, F.5
Gauduchon, P.6
-
45
-
-
0023792919
-
Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines
-
Scudiero D.A., Shoemaker R.H., Paull K.D., Monks A., Tierney S., Nofziger T.H., et al. Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines. Cancer Res. 48 (1988) 4827-4833
-
(1988)
Cancer Res.
, vol.48
, pp. 4827-4833
-
-
Scudiero, D.A.1
Shoemaker, R.H.2
Paull, K.D.3
Monks, A.4
Tierney, S.5
Nofziger, T.H.6
-
46
-
-
0026492817
-
Features of apoptotic cells measured by flow cytometry
-
Darzynkiewicz Z., Bruno S., Del Bino G., Gorczyca W., Hotz M.A., Lassota P., et al. Features of apoptotic cells measured by flow cytometry. Cytometry 13 (1992) 795-808
-
(1992)
Cytometry
, vol.13
, pp. 795-808
-
-
Darzynkiewicz, Z.1
Bruno, S.2
Del Bino, G.3
Gorczyca, W.4
Hotz, M.A.5
Lassota, P.6
-
47
-
-
3042734557
-
The cyclin-dependent kinase inhibitor p21(cip1/waf1) enhances the cytotoxicity of ganciclovir in HSV-tk transfected ovarian carcinoma cells
-
Ziller C., Lincet H., Muller C.D., Staedel C., Behr J.P., and Poulain L. The cyclin-dependent kinase inhibitor p21(cip1/waf1) enhances the cytotoxicity of ganciclovir in HSV-tk transfected ovarian carcinoma cells. Cancer Lett. 212 (2004) 43-52
-
(2004)
Cancer Lett.
, vol.212
, pp. 43-52
-
-
Ziller, C.1
Lincet, H.2
Muller, C.D.3
Staedel, C.4
Behr, J.P.5
Poulain, L.6
-
48
-
-
6844250967
-
Cancer incidence and mortality in France in 1975-95
-
Menegoz F., Black R.J., Arveux P., Magne V., Ferlay J., Buemi A., et al. Cancer incidence and mortality in France in 1975-95. Eur. J. Cancer Prev. 6 (1997) 442-466
-
(1997)
Eur. J. Cancer Prev.
, vol.6
, pp. 442-466
-
-
Menegoz, F.1
Black, R.J.2
Arveux, P.3
Magne, V.4
Ferlay, J.5
Buemi, A.6
-
49
-
-
0028867806
-
Current status of chemotherapy for ovarian cancer
-
Ozols R.F. Current status of chemotherapy for ovarian cancer. Semin. Oncol. 22 (1995) 61-66
-
(1995)
Semin. Oncol.
, vol.22
, pp. 61-66
-
-
Ozols, R.F.1
-
50
-
-
0029855440
-
Immunohistochemical analysis of Bcl-2 family proteins in adenocarcinomas of the stomach
-
Krajewska M., Fenoglio-Preiser C.M., Krajewski S., Song K., Macdonald J.S., Stemmerman G., et al. Immunohistochemical analysis of Bcl-2 family proteins in adenocarcinomas of the stomach. Am. J. Pathol. 149 (1996) 1449-1457
-
(1996)
Am. J. Pathol.
, vol.149
, pp. 1449-1457
-
-
Krajewska, M.1
Fenoglio-Preiser, C.M.2
Krajewski, S.3
Song, K.4
Macdonald, J.S.5
Stemmerman, G.6
-
51
-
-
0032422475
-
Apoptosis inhibiting factor Bcl-xL might be the crucial member of the Bcl-2 gene family in colorectal cancer
-
Maurer C.A., Friess H., Buhler S.S., Wahl B.R., Graber H., Zimmermann A., et al. Apoptosis inhibiting factor Bcl-xL might be the crucial member of the Bcl-2 gene family in colorectal cancer. Dig. Dis. Sci. 43 (1998) 2641-2648
-
(1998)
Dig. Dis. Sci.
, vol.43
, pp. 2641-2648
-
-
Maurer, C.A.1
Friess, H.2
Buhler, S.S.3
Wahl, B.R.4
Graber, H.5
Zimmermann, A.6
-
52
-
-
0027282044
-
bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
-
Boise L.H., Gonzalez-Garcia M., Postema C.E., Ding L., Lindsten T., Turka L.A., et al. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74 (1993) 597-608
-
(1993)
Cell
, vol.74
, pp. 597-608
-
-
Boise, L.H.1
Gonzalez-Garcia, M.2
Postema, C.E.3
Ding, L.4
Lindsten, T.5
Turka, L.A.6
-
53
-
-
0028170778
-
bcl-XL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria
-
Gonzalez-Garcia M., Perez-Ballestero R., Ding L., Duan L., Boise L.H., Thompson C.B., et al. bcl-XL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria. Development 120 (1994) 3033-3042
-
(1994)
Development
, vol.120
, pp. 3033-3042
-
-
Gonzalez-Garcia, M.1
Perez-Ballestero, R.2
Ding, L.3
Duan, L.4
Boise, L.H.5
Thompson, C.B.6
-
54
-
-
0027362667
-
Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes
-
Krajewski S., Tanaka S., Takayama S., Schibler M.J., Fenton W., and Reed J.C. Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes. Cancer Res. 53 (1993) 4701-4714
-
(1993)
Cancer Res.
, vol.53
, pp. 4701-4714
-
-
Krajewski, S.1
Tanaka, S.2
Takayama, S.3
Schibler, M.J.4
Fenton, W.5
Reed, J.C.6
-
55
-
-
0028335717
-
Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo
-
Miyashita T., Krajewski S., Krajewska M., Wang H.G., Lin H.K., Liebermann D.A., et al. Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene 9 (1994) 1799-1805
-
(1994)
Oncogene
, vol.9
, pp. 1799-1805
-
-
Miyashita, T.1
Krajewski, S.2
Krajewska, M.3
Wang, H.G.4
Lin, H.K.5
Liebermann, D.A.6
-
56
-
-
1842830762
-
Modulation of Janus kinase 2 by cisplatin in cancer cells
-
Song H., Sondak V.K., Barber D.L., Reid T.J., and Lin J. Modulation of Janus kinase 2 by cisplatin in cancer cells. Int. J. Oncol. 24 (2004) 1017-1026
-
(2004)
Int. J. Oncol.
, vol.24
, pp. 1017-1026
-
-
Song, H.1
Sondak, V.K.2
Barber, D.L.3
Reid, T.J.4
Lin, J.5
-
57
-
-
0037049879
-
Induction of apoptosis by cisplatin and its effect on cell cycle-related proteins and cell cycle changes in hepatoma cells
-
Qin L.F., and Ng I.O. Induction of apoptosis by cisplatin and its effect on cell cycle-related proteins and cell cycle changes in hepatoma cells. Cancer Lett. 175 (2002) 27-38
-
(2002)
Cancer Lett.
, vol.175
, pp. 27-38
-
-
Qin, L.F.1
Ng, I.O.2
-
58
-
-
23244448021
-
Neoadjuvant chemotherapy for epithelial ovarian cancer-role of apoptosis
-
Dutta T., Sharma H., Kumar L., Dinda A.K., Kumar S., Bhatla N., et al. Neoadjuvant chemotherapy for epithelial ovarian cancer-role of apoptosis. Cancer Chemother. Pharmacol. 56 (2005) 427-435
-
(2005)
Cancer Chemother. Pharmacol.
, vol.56
, pp. 427-435
-
-
Dutta, T.1
Sharma, H.2
Kumar, L.3
Dinda, A.K.4
Kumar, S.5
Bhatla, N.6
-
59
-
-
0029938724
-
Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death
-
Mazel S., Burtrum D., and Petrie H.T. Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death. J. Exp. Med. 183 (1996) 2219-2226
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2219-2226
-
-
Mazel, S.1
Burtrum, D.2
Petrie, H.T.3
-
60
-
-
0030476922
-
The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry
-
O'Reilly L.A., Huang D.C., and Strasser A. The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry. EMBO J. 15 (1996) 6979-6990
-
(1996)
EMBO J.
, vol.15
, pp. 6979-6990
-
-
O'Reilly, L.A.1
Huang, D.C.2
Strasser, A.3
-
61
-
-
0029805403
-
Bcl-2 has a cell cycle inhibitory function separable from its enhancement of cell survival
-
Vairo G., Innes K.M., and Adams J.M. Bcl-2 has a cell cycle inhibitory function separable from its enhancement of cell survival. Oncogene 13 (1996) 1511-1519
-
(1996)
Oncogene
, vol.13
, pp. 1511-1519
-
-
Vairo, G.1
Innes, K.M.2
Adams, J.M.3
-
62
-
-
0030449990
-
Bax alpha perturbs T cell development and affects cell cycle entry of T cells
-
Brady H.J., Gil-Gomez G., Kirberg J., and Berns A.J. Bax alpha perturbs T cell development and affects cell cycle entry of T cells. EMBO J. 15 (1996) 6991-7001
-
(1996)
EMBO J.
, vol.15
, pp. 6991-7001
-
-
Brady, H.J.1
Gil-Gomez, G.2
Kirberg, J.3
Berns, A.J.4
-
63
-
-
0029658664
-
Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage
-
Minn A.J., Boise L.H., and Thompson C.B. Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage. Genes Dev. 10 (1996) 2621-2631
-
(1996)
Genes Dev.
, vol.10
, pp. 2621-2631
-
-
Minn, A.J.1
Boise, L.H.2
Thompson, C.B.3
-
64
-
-
0027230693
-
p53 mutation is a common genetic event in ovarian carcinoma
-
Milner B.J., Allan L.A., Eccles D.M., Kitchener H.C., Leonard R.C., Kelly K.F., et al. p53 mutation is a common genetic event in ovarian carcinoma. Cancer Res. 53 (1993) 2128-2132
-
(1993)
Cancer Res.
, vol.53
, pp. 2128-2132
-
-
Milner, B.J.1
Allan, L.A.2
Eccles, D.M.3
Kitchener, H.C.4
Leonard, R.C.5
Kelly, K.F.6
-
65
-
-
0034769833
-
Killing of sarcoma cells by proapoptotic Bcl-X(S): role of the BH3 domain and regulation by Bcl-X(L)
-
Mitra R.S., Benedict M.A., Qian D., Foreman K.E., Ekhterae D., Nickoloff B.J., et al. Killing of sarcoma cells by proapoptotic Bcl-X(S): role of the BH3 domain and regulation by Bcl-X(L). Neoplasia 3 (2001) 437-445
-
(2001)
Neoplasia
, vol.3
, pp. 437-445
-
-
Mitra, R.S.1
Benedict, M.A.2
Qian, D.3
Foreman, K.E.4
Ekhterae, D.5
Nickoloff, B.J.6
-
66
-
-
0142138711
-
Conditional expression of exogenous Bcl-X(S) triggers apoptosis in human melanoma cells in vitro and delays growth of melanoma xenografts
-
Hossini A.M., Eberle J., Fecker L.F., Orfanos C.E., and Geilen C.C. Conditional expression of exogenous Bcl-X(S) triggers apoptosis in human melanoma cells in vitro and delays growth of melanoma xenografts. FEBS Lett. 553 (2003) 250-256
-
(2003)
FEBS Lett.
, vol.553
, pp. 250-256
-
-
Hossini, A.M.1
Eberle, J.2
Fecker, L.F.3
Orfanos, C.E.4
Geilen, C.C.5
-
67
-
-
0028972469
-
A recombinant bcl-x s adenovirus selectively induces apoptosis in cancer cells but not in normal bone marrow cells
-
Clarke M.F., Apel I.J., Benedict M.A., Eipers P.G., Sumantran V., Gonzalez-Garcia M., et al. A recombinant bcl-x s adenovirus selectively induces apoptosis in cancer cells but not in normal bone marrow cells. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 11024-11028
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 11024-11028
-
-
Clarke, M.F.1
Apel, I.J.2
Benedict, M.A.3
Eipers, P.G.4
Sumantran, V.5
Gonzalez-Garcia, M.6
-
68
-
-
0029664990
-
bcl-xs gene therapy induces apoptosis of human mammary tumors in nude mice
-
Ealovega M.W., McGinnis P.K., Sumantran V.N., Clarke M.F., and Wicha M.S. bcl-xs gene therapy induces apoptosis of human mammary tumors in nude mice. Cancer Res. 56 (1996) 1965-1969
-
(1996)
Cancer Res.
, vol.56
, pp. 1965-1969
-
-
Ealovega, M.W.1
McGinnis, P.K.2
Sumantran, V.N.3
Clarke, M.F.4
Wicha, M.S.5
-
69
-
-
0028979438
-
Overexpression of Bcl-XS sensitizes MCF-7 cells to chemotherapy-induced apoptosis
-
Sumantran V.N., Ealovega M.W., Nunez G., Clarke M.F., and Wicha M.S. Overexpression of Bcl-XS sensitizes MCF-7 cells to chemotherapy-induced apoptosis. Cancer Res. 55 (1995) 2507-2510
-
(1995)
Cancer Res.
, vol.55
, pp. 2507-2510
-
-
Sumantran, V.N.1
Ealovega, M.W.2
Nunez, G.3
Clarke, M.F.4
Wicha, M.S.5
-
70
-
-
0034183279
-
Overcoming of multidrug resistance by introducing the apoptosis gene, bcl-Xs, into MRP-overexpressing drug resistant cells
-
Ohi Y., Kim R., and Toge T. Overcoming of multidrug resistance by introducing the apoptosis gene, bcl-Xs, into MRP-overexpressing drug resistant cells. Int. J. Oncol. 16 (2000) 959-969
-
(2000)
Int. J. Oncol.
, vol.16
, pp. 959-969
-
-
Ohi, Y.1
Kim, R.2
Toge, T.3
-
71
-
-
0003826861
-
Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides
-
Taylor J.K., Zhang Q.Q., Wyatt J.R., and Dean N.M. Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides. Nat. Biotechnol. 17 (1999) 1097-1100
-
(1999)
Nat. Biotechnol.
, vol.17
, pp. 1097-1100
-
-
Taylor, J.K.1
Zhang, Q.Q.2
Wyatt, J.R.3
Dean, N.M.4
-
72
-
-
0042528617
-
Recent advances in the development of anticancer agents targeting cell death inhibitors in the Bcl-2 protein family
-
Shangary S., and Johnson D.E. Recent advances in the development of anticancer agents targeting cell death inhibitors in the Bcl-2 protein family. Leukemia 17 (2003) 1470-1481
-
(2003)
Leukemia
, vol.17
, pp. 1470-1481
-
-
Shangary, S.1
Johnson, D.E.2
-
73
-
-
1442335327
-
Shooting at survivors: Bcl-2 family members as drug targets for cancer
-
Juin P., Geneste O., Raimbaud E., and Hickman J.A. Shooting at survivors: Bcl-2 family members as drug targets for cancer. Biochim. Biophys. Acta 1644 (2004) 251-260
-
(2004)
Biochim. Biophys. Acta
, vol.1644
, pp. 251-260
-
-
Juin, P.1
Geneste, O.2
Raimbaud, E.3
Hickman, J.A.4
-
74
-
-
9944244102
-
Promises and challenges of targeting Bcl-2 anti-apoptotic proteins for cancer therapy
-
O'Neill J., Manion M., Schwartz P., and Hockenbery D.M. Promises and challenges of targeting Bcl-2 anti-apoptotic proteins for cancer therapy. Biochim. Biophys. Acta 1705 (2004) 43-51
-
(2004)
Biochim. Biophys. Acta
, vol.1705
, pp. 43-51
-
-
O'Neill, J.1
Manion, M.2
Schwartz, P.3
Hockenbery, D.M.4
-
75
-
-
22744437978
-
Apoptosis-based therapies and drug targets
-
Fischer U., and Schulze-Osthoff K. Apoptosis-based therapies and drug targets. Cell Death Differ. 12 Suppl. 1 (2005) 942-961
-
(2005)
Cell Death Differ.
, vol.12
, Issue.SUPPL. 1
, pp. 942-961
-
-
Fischer, U.1
Schulze-Osthoff, K.2
|