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Volumn 150, Issue 6, 2007, Pages 782-791

A comparison of the pharmacological properties of guinea-pig and human recombinant 5-HT 4 receptors

Author keywords

5 HT 4; 5 hydroxytryptamine; Adenylate cyclase; Gastrointestinal; Gastroprokinetic; Tegaserod

Indexed keywords

CYCLIC AMP; SEROTONIN 4 RECEPTOR; TEGASEROD;

EID: 33947311195     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707154     Document Type: Article
Times cited : (13)

References (56)
  • 1
    • 0036118814 scopus 로고    scopus 로고
    • Irritable bowel syndrome: Update on pathogenesis and management
    • Alaradi O, Barkin JS (2002). Irritable bowel syndrome: update on pathogenesis and management. Med Princ Pract 11: 2-17.
    • (2002) Med Princ Pract , vol.11 , pp. 2-17
    • Alaradi, O.1    Barkin, J.S.2
  • 2
    • 0034745301 scopus 로고    scopus 로고
    • 4(b) receptors have nearly identical pharmacology and are both expressed in human atrium and ventricle. Naunyn Schmiedebergs Arch Pharmacol 363: 146-160.
    • 4(b) receptors have nearly identical pharmacology and are both expressed in human atrium and ventricle. Naunyn Schmiedebergs Arch Pharmacol 363: 146-160.
  • 3
    • 0032970989 scopus 로고    scopus 로고
    • A review of central 5-HT receptors and their function
    • Barnes NM, Sharp T (1999). A review of central 5-HT receptors and their function. Neuropharmacology 38: 1083-1152.
    • (1999) Neuropharmacology , vol.38 , pp. 1083-1152
    • Barnes, N.M.1    Sharp, T.2
  • 7
    • 0032434460 scopus 로고    scopus 로고
    • Pleiotropic behavior of 5-HT2A and 5-HT2C receptor agonists
    • Berg KA, Clarke WP, Maayani S, Goldfarb J (1998). Pleiotropic behavior of 5-HT2A and 5-HT2C receptor agonists. Ann NY Acad Sci 861: 104-110.
    • (1998) Ann NY Acad Sci , vol.861 , pp. 104-110
    • Berg, K.A.1    Clarke, W.P.2    Maayani, S.3    Goldfarb, J.4
  • 8
    • 0021058380 scopus 로고
    • Operational models of pharmacological agonism
    • Black JW, Leff P (1983). Operational models of pharmacological agonism. Proc R Soc London Ser B 220: 141-162.
    • (1983) Proc R Soc London Ser B , vol.220 , pp. 141-162
    • Black, J.W.1    Leff, P.2
  • 10
    • 0038555362 scopus 로고    scopus 로고
    • 7(a) receptor and Gs. Receptor Channel 9: 107-116.
    • 7(a) receptor and Gs. Receptor Channel 9: 107-116.
  • 12
    • 4043174877 scopus 로고    scopus 로고
    • Advances in pharmacological treatments of IBS
    • Camilleri M (2004). Advances in pharmacological treatments of IBS. J Pediatr Gastroenterol Nutr 39: S766-S767.
    • (2004) J Pediatr Gastroenterol Nutr , vol.39
    • Camilleri, M.1
  • 14
    • 0032938367 scopus 로고    scopus 로고
    • 4 receptor splice variants show marked constitutive activity: Role of the C-terminal intracellular domain
    • 4 receptor splice variants show marked constitutive activity: role of the C-terminal intracellular domain. Mol Pharmacol 55: 910-920.
    • (1999) Mol Pharmacol , vol.55 , pp. 910-920
    • Claeysen, S.1    Sebben, M.2    Becamel, C.3    Bockaert, J.4    Dumuis, A.5
  • 16
    • 33646758583 scopus 로고    scopus 로고
    • 4 receptor agonists at gastric versus cardiac receptors: An operational framework to explain and quantify organ specific behaviour
    • 4 receptor agonists at gastric versus cardiac receptors: an operational framework to explain and quantify organ specific behaviour. J Pharmacol Exp Ther 317: 955-964.
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 955-964
    • De Maeyer, J.H.1    Prins, N.H.2    Schuurkes, J.A.3    Lefebvre, R.A.4
  • 17
    • 0036024222 scopus 로고    scopus 로고
    • Prucalopride, a systemic enterokinetic, for the treatment of constipation
    • Emmanuel AV, Roy AJ, Nicholls TJ, Kamm MA (2002). Prucalopride, a systemic enterokinetic, for the treatment of constipation. Aliment Pharmacol Ther 16: 1347-1356.
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 1347-1356
    • Emmanuel, A.V.1    Roy, A.J.2    Nicholls, T.J.3    Kamm, M.A.4
  • 18
    • 0142091274 scopus 로고    scopus 로고
    • 4 receptor-mediated facilitation of fast synaptic transmission in the guinea-pig ileum myenteric plexus
    • 4 receptor-mediated facilitation of fast synaptic transmission in the guinea-pig ileum myenteric plexus. Neurogastroenterol Motil 5: 523-529.
    • (2003) Neurogastroenterol Motil , vol.5 , pp. 523-529
    • Galligan, J.J.1    Pan, H.2    Messori, E.3
  • 20
    • 0032919084 scopus 로고    scopus 로고
    • Review article: Roles played by 5-hydroxytryptamine in the physiology of the bowel
    • Gershon MD (1999). Review article: roles played by 5-hydroxytryptamine in the physiology of the bowel. Aliment Pharmacol Ther 13: 15-30.
    • (1999) Aliment Pharmacol Ther , vol.13 , pp. 15-30
    • Gershon, M.D.1
  • 21
    • 0343145638 scopus 로고    scopus 로고
    • 4 receptor modulation of tachykinergic excitation of rat oesophageal tunica muscularis mucosae
    • 4 receptor modulation of tachykinergic excitation of rat oesophageal tunica muscularis mucosae. Eur J Pharmacol 323: 229-233.
    • (1997) Eur J Pharmacol , vol.323 , pp. 229-233
    • Goldhill, J.1    Porquet, M.F.2    Angel, I.3
  • 22
    • 0031595212 scopus 로고    scopus 로고
    • 4 receptor agonists initiate the peristaltic reflex in human, rat, and guinea pig intestine
    • 4 receptor agonists initiate the peristaltic reflex in human, rat, and guinea pig intestine. Gastroenterology 115: 370-380.
    • (1998) Gastroenterology , vol.115 , pp. 370-380
    • Grider, J.R.1    Foxx-Orenstein, A.E.2    Jin, J.G.3
  • 26
    • 0036119338 scopus 로고    scopus 로고
    • Molecular, pharmacological and functional diversity of 5-HT receptors
    • Hoyer D, Hannon JP, Martin GR (2002). Molecular, pharmacological and functional diversity of 5-HT receptors. Pharmacol Biochem Behav 71: 533-554.
    • (2002) Pharmacol Biochem Behav , vol.71 , pp. 533-554
    • Hoyer, D.1    Hannon, J.P.2    Martin, G.R.3
  • 28
    • 10644271570 scopus 로고    scopus 로고
    • Review article: Tegaserod for chronic constipation
    • Johanson JF (2004). Review article: tegaserod for chronic constipation. Aliment Pharmacol Ther 20: 20-24.
    • (2004) Aliment Pharmacol Ther , vol.20 , pp. 20-24
    • Johanson, J.F.1
  • 29
    • 0034943985 scopus 로고    scopus 로고
    • 4 receptor agonist, TS-951, in vitro. Pharmacology 63: 8-16.
    • 4 receptor agonist, TS-951, in vitro. Pharmacology 63: 8-16.
  • 30
    • 0036177114 scopus 로고    scopus 로고
    • Drug efficacy at G protein-coupled receptors
    • Kenakin T (2002). Drug efficacy at G protein-coupled receptors. Annu Rev Pharmacol Toxicol 42: 349-379.
    • (2002) Annu Rev Pharmacol Toxicol , vol.42 , pp. 349-379
    • Kenakin, T.1
  • 33
    • 0036152825 scopus 로고    scopus 로고
    • 4 receptor variant that lacks the alternatively spliced carboxy terminal exon
    • 4 receptor variant that lacks the alternatively spliced carboxy terminal exon. Br J Pharmacol 135: 135-142.
    • (2002) Br J Pharmacol , vol.135 , pp. 135-142
    • Leclere, P.G.1    Lefebvre, R.A.2
  • 42
    • 0034672622 scopus 로고    scopus 로고
    • Diverse signaling by 5-hydroxytryptamine (5-HT) receptors
    • Pauwels PJ (2000). Diverse signaling by 5-hydroxytryptamine (5-HT) receptors. Biochem Pharmacol 60: 1743-1750.
    • (2000) Biochem Pharmacol , vol.60 , pp. 1743-1750
    • Pauwels, P.J.1
  • 44
    • 0033709510 scopus 로고    scopus 로고
    • 4 receptors on cholinergic nerves involved in contractility of canine and human large intestine longitudinal muscle
    • 4 receptors on cholinergic nerves involved in contractility of canine and human large intestine longitudinal muscle. Br J Pharmacol 131: 927-932.
    • (2000) Br J Pharmacol , vol.131 , pp. 927-932
    • Prins, N.H.1    Akkermans, L.M.2    Lefebvre, R.A.3    Schuurkes, J.A.4
  • 49
    • 0029826824 scopus 로고    scopus 로고
    • 5-Hydroxytryptamine and functional bowel disorders
    • Sanger GJ (1996). 5-Hydroxytryptamine and functional bowel disorders. Neurogastroenterol Motil 8: 319-331.
    • (1996) Neurogastroenterol Motil , vol.8 , pp. 319-331
    • Sanger, G.J.1
  • 50
    • 0029057309 scopus 로고
    • Serotonin receptors: Subtypes, functional responses and therapeutic relevance
    • Saxena PR (1995). Serotonin receptors: subtypes, functional responses and therapeutic relevance. Pharmacol Ther 66: 339-368.
    • (1995) Pharmacol Ther , vol.66 , pp. 339-368
    • Saxena, P.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.