Differential effects of 5-hydroxytryptamine4 receptor agonists at gastric versus cardiac receptors: An operational framework to explain and quantify organ-specific behavior

Journal of Pharmacology and Experimental Therapeutics

Volumn 317, Issue 3, 2006, Pages 955-964

  De Maeyer, Joris H ^a,b   Prins, Nicolaas H ^c   Schuurkes, Jan A J ^b   Lefebvre, Romain A ^a  

^a GHENT UNIVERSITY   (Belgium)

^b JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^c PHARSIGHT CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 3 INDOLECARBOXYLIC ACID [1 [2 (METHYLSULFONYLAMINO)ETHYL] 4 PIPERIDINYLMETHYL] ESTER; 4 AMINO 5 CHLORO 2,2 DIMETHYL 2,3 DIHYDROBENZOFURAN 7 CARBOXYLIC ACID [3 HYDROXY 1 (3 METHOXYPROPYL)PIPERIDIN 4YLMETHYL]AMIDE; AMIDE; PRUCALOPRIDE; SEROTONIN 4 AGONIST; TEGASEROD; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFECT; FEMALE; HEART ATRIUM CONTRACTION; IN VITRO STUDY; MUSCLE CONTRACTION; NONHUMAN; PRIORITY JOURNAL; STOMACH; STOMACH MUSCLE; SWINE;

ANIMALS; HEART ATRIA; MODELS, BIOLOGICAL; MUSCLE CONTRACTION; MUSCLE, SMOOTH; MYOCARDIAL CONTRACTION; MYOCARDIUM; ORGAN SPECIFICITY; RECEPTORS, SEROTONIN, 5-HT4; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; STOMACH; SWINE;

EID: 33646758583     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.101329     Document Type: Article

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