Induction of potent and long-lasting CD4 and CD8 T-cell responses against hepatitis C virus by immunization with viral antigens plus poly(I:C) and anti-CD40

Antiviral Research

Volumn 74, Issue 1, 2007, Pages 25-35

  Zabaleta, Aintzane ^a   Arribillaga, Laura ^a   Llopiz, Diana ^a   Dotor, Javier ^a   Lasarte, Juan J ^a   Prieto, Jesús ^a   Borrás Cuesta, Francisco ^a   Esteban, Juan I ^b   Quer, Josep ^b   Vayreda, Francesc ^c   Sarobe, Pablo ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^c INOVA DIAGNOSTICS INC   (United States)

Author keywords

Adjuvant; Dendritic cell; Hepatitis C; T cell; Vaccination

Indexed keywords

CD4 ANTIGEN; CD40 ANTIGEN; CD8 ANTIGEN; CYTOKINE; EPITOPE; GLYCOPROTEIN E1; HEPATITIS C VACCINE; IMMUNOLOGICAL ADJUVANT; NONSTRUCTURAL PROTEIN 3; POLYINOSINIC POLYCYTIDYLIC ACID; VIRUS ANTIGEN;

ADJUVANT THERAPY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CELL MATURATION; CELLULAR IMMUNITY; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DENDRITIC CELL; DRUG DOSE COMPARISON; DRUG POTENCY; DRUG POTENTIATION; HEPATITIS C; HEPATITIS C VIRUS; IMMUNIZATION; MONOTHERAPY; MOUSE; NATURAL KILLER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TH1 CELL; VIRUS IMMUNITY;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES; ANTIBODY SPECIFICITY; ANTIGENS, CD40; ANTIGENS, VIRAL; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINE, TUMOR; CYTOKINES; DENDRITIC CELLS; DRUG SYNERGISM; EPITOPES, T-LYMPHOCYTE; HEPACIVIRUS; HEPATITIS C; HUMANS; IMMUNIZATION; INJECTIONS, INTRAPERITONEAL; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; PEPTIDES; POLY I-C; TIME FACTORS; VIRAL NONSTRUCTURAL PROTEINS;

HEPATITIS C VIRUS; MUS;

EID: 33847681398     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.antiviral.2007.01.001     Document Type: Article

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