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Volumn 11, Issue 12, 1999, Pages 2025-2033

T(h)1 but not T(h)0 cell help is efficient to induce cytotoxic T lymphocytes by immunization with short synthetic peptides

Author keywords

Cytokines; Cytotoxic T lymphocyte induction; T cell help; T(h) determinant

Indexed keywords

CD4 ANTIGEN; CYTOKINE; MUTANT PROTEIN; MYOGLOBIN; OVALBUMIN; SYNTHETIC PEPTIDE; VIRUS PROTEIN;

EID: 0343484313     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/11.12.2025     Document Type: Article
Times cited : (22)

References (59)
  • 1
    • 0018138586 scopus 로고
    • Transfer of specific cytotoxic T lymphocytes protects mice inoculated with influenza virus
    • Yap, K. L., Ada, G. L. and McKenzie, I. F. 1978. Transfer of specific cytotoxic T lymphocytes protects mice inoculated with influenza virus. Nature 273:238.
    • (1978) Nature , vol.273 , pp. 238
    • Yap, K.L.1    Ada, G.L.2    McKenzie, I.F.3
  • 2
    • 0018753961 scopus 로고
    • MHC-restricted cytotoxic T cells: Studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness
    • Zinkernagel, R. M. and Doherty, P. C. 1979. MHC-restricted cytotoxic T cells: studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness. Adv. Immunol. 27:51.
    • (1979) Adv. Immunol. , vol.27 , pp. 51
    • Zinkernagel, R.M.1    Doherty, P.C.2
  • 3
    • 0021227280 scopus 로고
    • Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus: Clearance of virus in vivo
    • Byrne, J. A. and Oldstone, M. B. 1984. Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus: clearance of virus in vivo. J. Virol. 51:682.
    • (1984) J. Virol. , vol.51 , pp. 682
    • Byrne, J.A.1    Oldstone, M.B.2
  • 4
    • 0022647790 scopus 로고
    • Influenza nucleoprotein-specific cytotoxic T-cell clones are protective in vivo
    • Taylor, P. M. and Askonas, B. A. 1986. Influenza nucleoprotein-specific cytotoxic T-cell clones are protective in vivo. Immunology 58:417.
    • (1986) Immunology , vol.58 , pp. 417
    • Taylor, P.M.1    Askonas, B.A.2
  • 8
    • 0025886953 scopus 로고
    • Adoptive T cell therapy of tumors: Mechanisms operative in the recognition and elimination of tumor cells
    • Greenberg, P. D. 1991. Adoptive T cell therapy of tumors: mechanisms operative in the recognition and elimination of tumor cells. Adv. Immunol. 49:281.
    • (1991) Adv. Immunol. , vol.49 , pp. 281
    • Greenberg, P.D.1
  • 12
    • 0026633946 scopus 로고
    • Induction of cytotoxic T cells to a cross-reactive epitope in the hepatitis C virus nonstructural RNA polymerase-like protein
    • Shirai, M., Akatsuka, T., Pendleton, C. D., Houghten, R., Wychowski, C., Mihalik, K., Feinstone, S. and Berzofsky, J. A. 1992. Induction of cytotoxic T cells to a cross-reactive epitope in the hepatitis C virus nonstructural RNA polymerase-like protein. J. Virol. 66:4098.
    • (1992) J. Virol. , vol.66 , pp. 4098
    • Shirai, M.1    Akatsuka, T.2    Pendleton, C.D.3    Houghten, R.4    Wychowski, C.5    Mihalik, K.6    Feinstone, S.7    Berzofsky, J.A.8
  • 13
    • 0027328790 scopus 로고
    • + cytotoxic T lymphocytes by immunization with syngeneic irradiated HIV-1 envelope derived peptide-pulsed dendritic cells
    • + cytotoxic T lymphocytes by immunization with syngeneic irradiated HIV-1 envelope derived peptide-pulsed dendritic cells. Int. Immunol. 5:849.
    • (1993) Int. Immunol. , vol.5 , pp. 849
    • Takahashi, H.1    Nakagawa, Y.2    Yokomuro, K.3    Berzofsky, J.A.4
  • 14
    • 0030048724 scopus 로고    scopus 로고
    • Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity
    • Celluzzi, C. M., Mayordomo, J. I., Storkus, W. J., Lotze, M. T. and Falo, L. D., Jr. 1996. Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity. J. Exp. Med. 183:283.
    • (1996) J. Exp. Med. , vol.183 , pp. 283
    • Celluzzi, C.M.1    Mayordomo, J.I.2    Storkus, W.J.3    Lotze, M.T.4    Falo L.D., Jr.5
  • 15
    • 0027292868 scopus 로고
    • Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages
    • Kovacsovics Bankowski, M., Clark, K., Benacerraf, B. and Rock, K. L. 1993. Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages. Proc. Natl Acad. Sci. USA 90:4942.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 4942
    • Kovacsovics Bankowski, M.1    Clark, K.2    Benacerraf, B.3    Rock, K.L.4
  • 16
    • 0342457028 scopus 로고    scopus 로고
    • Priming of cytotoxic T lymphocytes by five heat-aggregated antigens in vivo: Conditions, efficiency, and relation to antibody responses
    • Speidel, K., Osen, W., Faath, S., Hilgert, I., Obst, R., Braspenning, J., Momburg, F., Hammerling, G. J. and Rammensee, H. G. 1997. Priming of cytotoxic T lymphocytes by five heat-aggregated antigens in vivo: conditions, efficiency, and relation to antibody responses. Eur. J. Immunol. 27:2391.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 2391
    • Speidel, K.1    Osen, W.2    Faath, S.3    Hilgert, I.4    Obst, R.5    Braspenning, J.6    Momburg, F.7    Hammerling, G.J.8    Rammensee, H.G.9
  • 17
    • 0024389666 scopus 로고
    • In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine
    • Deres, K., Schild, H., Wiesmuller, K. H., Jung, G. and Rammensee, H. G. 1989. In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine. Nature 342:561.
    • (1989) Nature , vol.342 , pp. 561
    • Deres, K.1    Schild, H.2    Wiesmuller, K.H.3    Jung, G.4    Rammensee, H.G.5
  • 18
    • 0025287307 scopus 로고
    • Antiviral cytotoxic T cell response induced by in vivo priming with a free synthetic peptide
    • Aichele, P., Hengartner, H., Zinkernagel, R. M. and Schulz, M. 1990. Antiviral cytotoxic T cell response induced by in vivo priming with a free synthetic peptide. J. Exp. Med. 171:1815.
    • (1990) J. Exp. Med. , vol.171 , pp. 1815
    • Aichele, P.1    Hengartner, H.2    Zinkernagel, R.M.3    Schulz, M.4
  • 20
    • 0025748605 scopus 로고
    • Priming of influenza virus-specific cytotoxic T lymphocytes in vivo by short synthetic peptides
    • Gao, X. M., Zheng, B., Liew, F. Y., Brett, S. and Tite, J. 1991. Priming of influenza virus-specific cytotoxic T lymphocytes in vivo by short synthetic peptides. J. Immunol. 147:3268.
    • (1991) J. Immunol. , vol.147 , pp. 3268
    • Gao, X.M.1    Zheng, B.2    Liew, F.Y.3    Brett, S.4    Tite, J.5
  • 21
    • 0026657070 scopus 로고
    • In vivo primary induction of virus-specific CTL by immunization with 9-mer synthetic peptides
    • Zhou, X., Berg, L., Motal, U. M. and Jondal, M. 1992 In vivo primary induction of virus-specific CTL by immunization with 9-mer synthetic peptides. J. Immunol. Methods 153:193.
    • (1992) J. Immunol. Methods , vol.153 , pp. 193
    • Zhou, X.1    Berg, L.2    Motal, U.M.3    Jondal, M.4
  • 22
    • 0027480311 scopus 로고
    • Strict peptide length is not required for the induction of cytotoxic T lymphocyte-mediated antiviral protection by peptide vaccination
    • Kast, W. M., Brandt, R. M. and Melief, C. J. 1993. Strict peptide length is not required for the induction of cytotoxic T lymphocyte-mediated antiviral protection by peptide vaccination. Eur. J. Immunol. 23:1189.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1189
    • Kast, W.M.1    Brandt, R.M.2    Melief, C.J.3
  • 24
    • 0026563173 scopus 로고
    • Induction of cytotoxic T lymphocytes in mice against the principal neutralizing domain of HIV-1 by immunization with an engineered T-cytotoxic-T-helper synthetic peptide construct
    • Lasarte, J. J., Sarobe, P., Gullon, A., Prieto, J. and Borras Cuesta, F. 1992. Induction of cytotoxic T lymphocytes in mice against the principal neutralizing domain of HIV-1 by immunization with an engineered T-cytotoxic-T-helper synthetic peptide construct. Cell. Immunol. 141:211.
    • (1992) Cell. Immunol. , vol.141 , pp. 211
    • Lasarte, J.J.1    Sarobe, P.2    Gullon, A.3    Prieto, J.4    Borras Cuesta, F.5
  • 26
    • 0029975955 scopus 로고    scopus 로고
    • Candidate HIV type 1 multi-determinant cluster peptide-p18MN vaccine constructs elicit type 1 helper T cells, cytotoxic T cells, and neutralizing antibody, all using the same adjuvant immunization
    • Ahlers, J. D., Dunlop, N., Pendleton, C. D., Newman, M., Nara, P. L. and Berzofsky, J. A. 1996. Candidate HIV type 1 multi-determinant cluster peptide-P18MN vaccine constructs elicit type 1 helper T cells, cytotoxic T cells, and neutralizing antibody, all using the same adjuvant immunization. AIDS Res. Hum. Retroviruses 12:259.
    • (1996) AIDS Res. Hum. Retroviruses , vol.12 , pp. 259
    • Ahlers, J.D.1    Dunlop, N.2    Pendleton, C.D.3    Newman, M.4    Nara, P.L.5    Berzofsky, J.A.6
  • 27
    • 0026739624 scopus 로고
    • T helper epitopes enhance the cytotoxic response of mice immunized with MHC class I-restricted malaria peptides
    • Widmann, C., Romero, P., Maryanski, J. L., Corradin, G. and Valmori, D. 1992. T helper epitopes enhance the cytotoxic response of mice immunized with MHC class I-restricted malaria peptides. J. Immunol. Methods 155:95.
    • (1992) J. Immunol. Methods , vol.155 , pp. 95
    • Widmann, C.1    Romero, P.2    Maryanski, J.L.3    Corradin, G.4    Valmori, D.5
  • 28
    • 0028306427 scopus 로고
    • Induction of a cytotoxic T cell response by co-injection of a T helper peptide and a cytotoxic T lymphocyte peptide in incomplete freund's adjuvant (IFA): Further enhancement by pre-injection of IFA alone
    • Valmori, D., Romero, J. F., Men, Y., Maryanski, J. L., Romero, P. and Corradin, G. 1994. Induction of a cytotoxic T cell response by co-injection of a T helper peptide and a cytotoxic T lymphocyte peptide in incomplete Freund's adjuvant (IFA): further enhancement by pre-injection of IFA alone. Eur. J. Immunol. 24:1458.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1458
    • Valmori, D.1    Romero, J.F.2    Men, Y.3    Maryanski, J.L.4    Romero, P.5    Corradin, G.6
  • 30
    • 0028589597 scopus 로고
    • Increased susceptibility of mice infected with Schistosoma mansoni to recombinant vaccinia virus: Association of viral persistence with egg granuloma formation
    • Actor, J. K., Marshall, M. A., Eltoum, I. A., Buller, R. M., Berzofsky, J. A. and Sher, A. 1994. Increased susceptibility of mice infected with Schistosoma mansoni to recombinant vaccinia virus: association of viral persistence with egg granuloma formation. Eur. J. Immunol. 24:3050.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 3050
    • Actor, J.K.1    Marshall, M.A.2    Eltoum, I.A.3    Buller, R.M.4    Berzofsky, J.A.5    Sher, A.6
  • 32
    • 0031015971 scopus 로고    scopus 로고
    • Induction of cytotoxic T-cell response against hepatitis C virus structural antigens using a defective recombinant adenovirus
    • Bruna-Romero, O., Lasarte, J. J., Wilkinson, G., Grace, K., Clarke, B., Borras-Cuesta, F. and Prieto, J. 1997. Induction of cytotoxic T-cell response against hepatitis C virus structural antigens using a defective recombinant adenovirus. Hepatology 25:470.
    • (1997) Hepatology , vol.25 , pp. 470
    • Bruna-Romero, O.1    Lasarte, J.J.2    Wilkinson, G.3    Grace, K.4    Clarke, B.5    Borras-Cuesta, F.6    Prieto, J.7
  • 33
    • 20744456789 scopus 로고
    • Solid phase peptide synthesis. I. The synthesis of a tetrapeptide
    • Merrifield, R. B. 1963. Solid phase peptide synthesis. I. The synthesis of a tetrapeptide. J. Am. Chem. Soc. 85:2149.
    • (1963) J. Am. Chem. Soc. , vol.85 , pp. 2149
    • Merrifield, R.B.1
  • 34
    • 37049106853 scopus 로고
    • Peptide synthesis II. Procedures for solid phase synthesis using N-fluorenyl methoxycarbonyl aminoacids on polyamide supports. Sintesis of substance P and of acyl carrier protein 65-74 decapeptide
    • Atherton, E., Logan, J. C. and Sheppard, R. C. 1989. Peptide synthesis II. Procedures for solid phase synthesis using N-fluorenyl methoxycarbonyl aminoacids on polyamide supports. Sintesis of substance P and of acyl carrier protein 65-74 decapeptide. J. Chem. Soc. Perkin Trans. 1:538.
    • (1989) J. Chem. Soc. Perkin Trans. , vol.1 , pp. 538
    • Atherton, E.1    Logan, J.C.2    Sheppard, R.C.3
  • 36
    • 0014772602 scopus 로고
    • Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides
    • Kaiser, E., Colescott, R. L., Bossinger, C. D. and Cook, P. I. 1970. Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides. Anal. Biochem. 34:595.
    • (1970) Anal. Biochem. , vol.34 , pp. 595
    • Kaiser, E.1    Colescott, R.L.2    Bossinger, C.D.3    Cook, P.I.4
  • 37
    • 0014251127 scopus 로고
    • Quantitative assay of the lytic action of immune lymphoid cells on 51-Cr-labeled allogeneic target cells in vitro; inhibition by isoantibody and by drugs
    • Brunner, K. T., Mauel, J., Cerottini, J, C. and Chapuis, B. 1968. Quantitative assay of the lytic action of immune lymphoid cells on 51-Cr-labeled allogeneic target cells in vitro; inhibition by isoantibody and by drugs. Immunology 14:181.
    • (1968) Immunology , vol.14 , pp. 181
    • Brunner, K.T.1    Mauel, J.2    Cerottini, J.C.3    Chapuis, B.4
  • 38
    • 0019468220 scopus 로고
    • Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis
    • Taswell, C. 1981. Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis. J. Immunol. 126:1614.
    • (1981) J. Immunol. , vol.126 , pp. 1614
    • Taswell, C.1
  • 39
    • 0023571895 scopus 로고
    • T lymphocyte response to bacteriophage lambda repressor cl protein. Recognition of the same peptide presented by la molecules of different haplotypes
    • Lai, M. Z., Ross, D. T., Guillet, J. G., Briner, T. J., Gefter, M. L. and Smith, J. A. 1987. T lymphocyte response to bacteriophage lambda repressor cl protein. Recognition of the same peptide presented by la molecules of different haplotypes. J. Immunol. 139:3973.
    • (1987) J. Immunol. , vol.139 , pp. 3973
    • Lai, M.Z.1    Ross, D.T.2    Guillet, J.G.3    Briner, T.J.4    Gefter, M.L.5    Smith, J.A.6
  • 40
    • 0028956971 scopus 로고
    • In vivo cytotoxic T-lymphocyte induction may take place via CD8 T helper lymphocytes
    • Lasarte, J. J., Sarobe, P., Prieto, J. and Borras-Cuesta, F. 1995. In vivo cytotoxic T-lymphocyte induction may take place via CD8 T helper lymphocytes. Res Immunol 146:35.
    • (1995) Res Immunol , vol.146 , pp. 35
    • Lasarte, J.J.1    Sarobe, P.2    Prieto, J.3    Borras-Cuesta, F.4
  • 41
    • 0026657070 scopus 로고
    • In vivo primary induction of virus-specific CTL by immunization with 9-mer synthetic peptides
    • Zhou, X., Berg, L., Motal, U. M. and Jondal, M. 1992. In vivo primary induction of virus-specific CTL by immunization with 9-mer synthetic peptides. J. Immunol. Methods 153:193.
    • (1992) J. Immunol. Methods , vol.153 , pp. 193
    • Zhou, X.1    Berg, L.2    Motal, U.M.3    Jondal, M.4
  • 43
    • 0030068733 scopus 로고    scopus 로고
    • Use of intrinsic and extrinsic helper epitopes for in vivo induction of anti-hepatitis C virus cytotoxic T lymphocytes (CTL) with CTL epitope peptide vaccines
    • Shirai, M., Chen, M., Arichi, T., Masaki, T., Nishioka, M., Newman, M., Nakazawa, T., Feinstone, S. M. and Berzofsky, J. A. 1996. Use of intrinsic and extrinsic helper epitopes for in vivo induction of anti-hepatitis C virus cytotoxic T lymphocytes (CTL) with CTL epitope peptide vaccines. J. Infect. Dis. 173:24.
    • (1996) J. Infect. Dis. , vol.173 , pp. 24
    • Shirai, M.1    Chen, M.2    Arichi, T.3    Masaki, T.4    Nishioka, M.5    Newman, M.6    Nakazawa, T.7    Feinstone, S.M.8    Berzofsky, J.A.9
  • 44
    • 0031018327 scopus 로고    scopus 로고
    • Antigen organization regulates cluster formation and induction of cytotoxic T lymphocytes by helper T cell subsets
    • Stuhler, G. and Schlossman, S. F. 1997. Antigen organization regulates cluster formation and induction of cytotoxic T lymphocytes by helper T cell subsets. Proc. Natl Acad. Sci. USA 94:622.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 622
    • Stuhler, G.1    Schlossman, S.F.2
  • 45
    • 0031814098 scopus 로고    scopus 로고
    • h2 inhibit antigen-dependent IL-12 secretion by dendritic cells
    • h2 inhibit antigen-dependent IL-12 secretion by dendritic cells. Eur. J. Immunol. 28:2003.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2003
    • Ria, F.1    Penna, G.2    Adorini, L.3
  • 46
    • 0032476615 scopus 로고    scopus 로고
    • Immune suppression by recombinant interleukin (rIL)-12 involves interferon gamma induction of nitric oxide synthase 2 (iNOS) activity: Inhibitors of NO generation reveal the extent of rIL-12 vaccine adjuvant effect
    • Koblish, H. K., Hunter, C. A., Wysocka, M., Trinchieri, G. and Lee, W. M. 1998. Immune suppression by recombinant interleukin (rIL)-12 involves Interferon gamma induction of nitric oxide synthase 2 (iNOS) activity: inhibitors of NO generation reveal the extent of rIL-12 vaccine adjuvant effect. J. Exp. Med. 188:1603.
    • (1998) J. Exp. Med. , vol.188 , pp. 1603
    • Koblish, H.K.1    Hunter, C.A.2    Wysocka, M.3    Trinchieri, G.4    Lee, W.M.5
  • 47
    • 0033579881 scopus 로고    scopus 로고
    • Interieukin 12 protects from a T helper type 1-mediated autoimmune disease, experimental autoimmune uveitis, through a mechanism involving interferon gamma, nitric oxide, and apoptosis
    • Tarrant, T. K., Silver, P. B., Wahlsten, J. L., Rizzo, L. V., Chan, C. C., Wiggert, B. and Caspi, R. R. 1999. Interieukin 12 protects from a T helper type 1-mediated autoimmune disease, experimental autoimmune uveitis, through a mechanism involving interferon gamma, nitric oxide, and apoptosis. J. Exp. Med. 189:219.
    • (1999) J. Exp. Med. , vol.189 , pp. 219
    • Tarrant, T.K.1    Silver, P.B.2    Wahlsten, J.L.3    Rizzo, L.V.4    Chan, C.C.5    Wiggert, B.6    Caspi, R.R.7
  • 48
    • 0033136294 scopus 로고    scopus 로고
    • Different doses of adenoviral vector expressing IL-12 enhance or depress the immune response to a co-administered antigen: The role of nitric oxide
    • Lasarte, J. J., Corrales, F. J., Casares, N., López-Díaz de Cerio, A., Qian, C., Xie, X., Borrás-Cuesta, F. and Prieto, J. 1999. Different doses of adenoviral vector expressing IL-12 enhance or depress the immune response to a co-administered antigen: the role of nitric oxide. J. Immunol. 162:5270.
    • (1999) J. Immunol. , vol.162 , pp. 5270
    • Lasarte, J.J.1    Corrales, F.J.2    Casares, N.3    López-Díaz De Cerio, A.4    Qian, C.5    Xie, X.6    Borrás-Cuesta, F.7    Prieto, J.8
  • 51
    • 0032482474 scopus 로고    scopus 로고
    • T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions
    • Schoenberger, S. P., Toes, R. E., van der Voort, E. I., Offringa, R. and Melief, C. J. 1998. T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature 393:480.
    • (1998) Nature , vol.393 , pp. 480
    • Schoenberger, S.P.1    Toes, R.E.2    Van Der Voort, E.I.3    Offringa, R.4    Melief, C.J.5
  • 52
    • 0029005321 scopus 로고
    • Bone marrow-generated dendritic cells pulsed with a class I-restricted peptide are potent inducers of cytotoxic T lymphocytes
    • Porgador, A. and Gilboa, E. 1995. Bone marrow-generated dendritic cells pulsed with a class I-restricted peptide are potent inducers of cytotoxic T lymphocytes. J. Exp. Med. 182:255.
    • (1995) J. Exp. Med. , vol.182 , pp. 255
    • Porgador, A.1    Gilboa, E.2
  • 54
    • 0029035637 scopus 로고
    • Human CTL epitopes encoded by human papillomavirus type 16 E6 and E7 identified through in vivo and in vitro immunogenicity studies of HLA-A*0201-binding peptides
    • Ressing, M. E., Sette, A., Brandt, R. M., Ruppert, J., Wentworth, P. A., Hartman, M., Oseroff, C., Grey, H. M., Melief, C. J. and Kast, W. M. 1995. Human CTL epitopes encoded by human papillomavirus type 16 E6 and E7 identified through in vivo and in vitro immunogenicity studies of HLA-A*0201-binding peptides. J. Immunol. 154:5934.
    • (1995) J. Immunol. , vol.154 , pp. 5934
    • Ressing, M.E.1    Sette, A.2    Brandt, R.M.3    Ruppert, J.4    Wentworth, P.A.5    Hartman, M.6    Oseroff, C.7    Grey, H.M.8    Melief, C.J.9    Kast, W.M.10
  • 55
    • 0032531164 scopus 로고    scopus 로고
    • Enhanced in vitro potency and in vivo immunogenicity of a CTL epitope from hepatitis C virus core protein following amino acid replacement at secondary HLA-A2.1 binding positions
    • Sarobe, P., Pendleton, C. D., Akatsuka, T., Lau, D., Engelhard, V. H., Feinstone, S. M. and Berzofsky, J. A. 1998. Enhanced in vitro potency and in vivo immunogenicity of a CTL epitope from hepatitis C virus core protein following amino acid replacement at secondary HLA-A2.1 binding positions. J. Clin. Invest. 102:1239.
    • (1998) J. Clin. Invest. , vol.102 , pp. 1239
    • Sarobe, P.1    Pendleton, C.D.2    Akatsuka, T.3    Lau, D.4    Engelhard, V.H.5    Feinstone, S.M.6    Berzofsky, J.A.7
  • 57
    • 0030291905 scopus 로고    scopus 로고
    • Structural requirements for synthetic immunogens to induce measles virus specific CTL responses
    • Partidos, C. D., Delmas, A. and Steward, M. W. 1996. Structural requirements for synthetic immunogens to induce measles virus specific CTL responses. Mol. Immunol. 33:1223.
    • (1996) Mol. Immunol. , vol.33 , pp. 1223
    • Partidos, C.D.1    Delmas, A.2    Steward, M.W.3
  • 59
    • 14844344681 scopus 로고
    • Protective CTL-dependent immunity and enhanced immunopathology in mice immunized by particle bombardment with DNA encoding an internal virion protein
    • Zarozinski, C. C., Fynan, E. F., Selin, L. K., Robinson, H. L. and Welsh, R. M. 1995. Protective CTL-dependent immunity and enhanced immunopathology in mice immunized by particle bombardment with DNA encoding an internal virion protein. J. Immunol. 154:4010.
    • (1995) J. Immunol. , vol.154 , pp. 4010
    • Zarozinski, C.C.1    Fynan, E.F.2    Selin, L.K.3    Robinson, H.L.4    Welsh, R.M.5


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