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Volumn 164, Issue 5, 2000, Pages 2372-2378

CpG-DNA activates in vivo T cell epitope presenting dendritic cells to trigger protective antiviral cytotoxic T cell responses

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; CD8 ANTIGEN; EPITOPE; FREUND ADJUVANT; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; T LYMPHOCYTE ANTIGEN; VIRUS GLYCOPROTEIN;

EID: 0034163408     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.5.2372     Document Type: Article
Times cited : (117)

References (51)
  • 1
    • 0027468145 scopus 로고
    • The biochemistry and cell biology of antigen processing and presentation
    • Germain, R. N., and D. H. Margulies. 1993. The biochemistry and cell biology of antigen processing and presentation. Annu. Rev. Immunol. 11:403.
    • (1993) Annu. Rev. Immunol. , vol.11 , pp. 403
    • Germain, R.N.1    Margulies, D.H.2
  • 2
    • 0020077493 scopus 로고
    • Helper activity is required for the in vivo generation of cytotoxic T lymphocytes
    • Keene, J. A., and J. Forman. 1982. Helper activity is required for the in vivo generation of cytotoxic T lymphocytes. J. Exp. Med. 155:768.
    • (1982) J. Exp. Med. , vol.155 , pp. 768
    • Keene, J.A.1    Forman, J.2
  • 3
    • 0024263475 scopus 로고
    • Cooperation between helper T cells and cytotoxic T lymphocyte precursors
    • Husmann, L. A., and M. J. Bevan. 1988. Cooperation between helper T cells and cytotoxic T lymphocyte precursors. Ann. NY Acad. Sci. 532:158.
    • (1988) Ann. NY Acad. Sci. , vol.532 , pp. 158
    • Husmann, L.A.1    Bevan, M.J.2
  • 6
    • 0031045622 scopus 로고    scopus 로고
    • Origin, maturation and antigen presenting function of dendritic cells
    • Cella, M., F. Sallusto, and A. Lanzavecchia. 1997. Origin, maturation and antigen presenting function of dendritic cells. Curr. Qpin. Immunol. 9:10.
    • (1997) Curr. Qpin. Immunol. , vol.9 , pp. 10
    • Cella, M.1    Sallusto, F.2    Lanzavecchia, A.3
  • 7
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392:245.
    • (1998) Nature , vol.392 , pp. 245
    • Banchereau, J.1    Steinman, R.M.2
  • 10
  • 12
    • 0033103128 scopus 로고    scopus 로고
    • Maturation, activation, and protection of dendritic cells induced by double-stranded RNA
    • Cella, M., M. Salio, Y. Sakakibara, H. Langen, I. Julkunen, and A. Lanzavecchia. 1999. Maturation, activation, and protection of dendritic cells induced by double-stranded RNA. J. Exp. Med. 189:821.
    • (1999) J. Exp. Med. , vol.189 , pp. 821
    • Cella, M.1    Salio, M.2    Sakakibara, Y.3    Langen, H.4    Julkunen, I.5    Lanzavecchia, A.6
  • 13
    • 0032995849 scopus 로고    scopus 로고
    • Bacterial CpG DNA activates immune cells to signal infectious danger
    • Wagner, H. 1999. Bacterial CpG DNA activates immune cells to signal infectious danger. Adv. Immunol. 73:329.
    • (1999) Adv. Immunol. , vol.73 , pp. 329
    • Wagner, H.1
  • 15
    • 0031774181 scopus 로고    scopus 로고
    • Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide
    • Kirschning, C. J., H. Wesche, A. T. Merrill, and M. Rothe. 1998. Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide. J. Exp. Med. 188:2091.
    • (1998) J. Exp. Med. , vol.188 , pp. 2091
    • Kirschning, C.J.1    Wesche, H.2    Merrill, A.T.3    Rothe, M.4
  • 17
    • 0030613651 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity
    • Chu, R. S., O. S. Targoni, A. M. Krieg, P. V. Lehmann, and C. V. Harding. 1997. CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity. J. Exp. Med. 186:1623.
    • (1997) J. Exp. Med. , vol.186 , pp. 1623
    • Chu, R.S.1    Targoni, O.S.2    Krieg, A.M.3    Lehmann, P.V.4    Harding, C.V.5
  • 19
    • 0032489829 scopus 로고    scopus 로고
    • DNA as an adjuvant: Capacity of insect DNA and synthetic oligodeoxynucleotides to augment T cell responses to specific antigen
    • Sun, S., H. Kishimoto, and J. Sprent. 1998. DNA as an adjuvant: capacity of insect DNA and synthetic oligodeoxynucleotides to augment T cell responses to specific antigen. J. Exp. Med. 187:1145.
    • (1998) J. Exp. Med. , vol.187 , pp. 1145
    • Sun, S.1    Kishimoto, H.2    Sprent, J.3
  • 20
    • 0030850462 scopus 로고    scopus 로고
    • CpG-containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: A new class of vaccine adjuvants
    • Lipford, G. B., M. Bauer, C. Blank, R. Reiter, H. Wagner, and K. Heeg. 1997. CpG-containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: a new class of vaccine adjuvants. Eur. J. Immunol. 27:2340.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 2340
    • Lipford, G.B.1    Bauer, M.2    Blank, C.3    Reiter, R.4    Wagner, H.5    Heeg, K.6
  • 21
    • 0031964257 scopus 로고    scopus 로고
    • CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen
    • Davis, H. L., R. Weeratna, T. J. Waldschmidt, L. Tygrett, J. Schorr, A. M. Krieg, and R. Weeranta. 1998. CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen. J. Immunol. 160: 870.
    • (1998) J. Immunol. , vol.160 , pp. 870
    • Davis, H.L.1    Weeratna, R.2    Waldschmidt, T.J.3    Tygrett, L.4    Schorr, J.5    Krieg, A.M.6    Weeranta, R.7
  • 22
    • 0031867535 scopus 로고    scopus 로고
    • Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells
    • Sparwasser, T., E. S. Koch, R. M. Vabulas, K. Heeg, G. B. Lipford, J. W. Ellwart, and H. Wagner. 1998. Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells. Eur. J. Immunol. 28:2045.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2045
    • Sparwasser, T.1    Koch, E.S.2    Vabulas, R.M.3    Heeg, K.4    Lipford, G.B.5    Ellwart, J.W.6    Wagner, H.7
  • 23
    • 0032531036 scopus 로고    scopus 로고
    • Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: A role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA
    • Jakob, T., P. S. Walker, A. M. Krieg, M. C. Udey, and J. C. Vogel. 1998. Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: a role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA. J. Immunol. 161:3042.
    • (1998) J. Immunol. , vol.161 , pp. 3042
    • Jakob, T.1    Walker, P.S.2    Krieg, A.M.3    Udey, M.C.4    Vogel, J.C.5
  • 26
    • 0026639652 scopus 로고
    • Detection of rare antigen-presenting cells by the lacZ T-cell activation assay suggests an expression cloning strategy for T-cell antigens
    • Karttunen, J., S. Sanderson, and N. Shastri. 1992. Detection of rare antigen-presenting cells by the lacZ T-cell activation assay suggests an expression cloning strategy for T-cell antigens. Proc: Natl. Acad. Sci. USA 89:6020.
    • (1992) Proc: Natl. Acad. Sci. USA , vol.89 , pp. 6020
    • Karttunen, J.1    Sanderson, S.2    Shastri, N.3
  • 28
    • 0025883707 scopus 로고
    • Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates
    • Battegay, M., S. Cooper, A. Althage, J. Banziger, H. Hengartner, and R. M. Zinkernagel. 1991. Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates. J. Virol. Methods 33:191.
    • (1991) J. Virol. Methods , vol.33 , pp. 191
    • Battegay, M.1    Cooper, S.2    Althage, A.3    Banziger, J.4    Hengartner, H.5    Zinkernagel, R.M.6
  • 29
    • 0029148878 scopus 로고
    • Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: Downregulation by cytokines and bacterial products
    • Sallusto, F., M. Cella, C. Danieli, and A. Lanzavecchia. 1995. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J. Exp. Med. 182:389.
    • (1995) J. Exp. Med. , vol.182 , pp. 389
    • Sallusto, F.1    Cella, M.2    Danieli, C.3    Lanzavecchia, A.4
  • 30
    • 0029914331 scopus 로고    scopus 로고
    • Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo
    • Kagi, D., B. Ledermann, K. Burki, R. M. Zinkernagel, and H. Hengartner. 1996. Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo. Annu. Rev. Immunol. 14:207.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 207
    • Kagi, D.1    Ledermann, B.2    Burki, K.3    Zinkernagel, R.M.4    Hengartner, H.5
  • 31
    • 0025761241 scopus 로고
    • Lower receptor avidity required for thymic clonal deletion than for effector T-cell function
    • Pircher, H., U. H. Rohrer, D. Moskophidis, R. M. Zinkernagel, and H. Hengartner. 1991. Lower receptor avidity required for thymic clonal deletion than for effector T-cell function. Nature 351:482.
    • (1991) Nature , vol.351 , pp. 482
    • Pircher, H.1    Rohrer, U.H.2    Moskophidis, D.3    Zinkernagel, R.M.4    Hengartner, H.5
  • 36
    • 0032521881 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis
    • Zimmermann, S., O. Egeter, S. Hausmann, G. B. Lipford, M. Rocken, H. Wagner, and K. Heeg. 1998. CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis. J. Immunol. 160:3627.
    • (1998) J. Immunol. , vol.160 , pp. 3627
    • Zimmermann, S.1    Egeter, O.2    Hausmann, S.3    Lipford, G.B.4    Rocken, M.5    Wagner, H.6    Heeg, K.7
  • 37
  • 38
  • 39
    • 0027284742 scopus 로고
    • Characterization of antigen-presenting cells that present exogenous antigens in association with class 1 MHC molecules
    • Rock, K. L., L. Rothstein, S. Gamble, and C. Heischacker. 1993. Characterization of antigen-presenting cells that present exogenous antigens in association with class 1 MHC molecules. J. Immunol. 150:438.
    • (1993) J. Immunol. , vol.150 , pp. 438
    • Rock, K.L.1    Rothstein, L.2    Gamble, S.3    Heischacker, C.4
  • 40
    • 0031867792 scopus 로고    scopus 로고
    • Dendritic cell/macrophage precursors capture exogenous antigen for MHC class 1 presentation by dendritic cells
    • Mitchell, D. A., S. K. Nair, and E. Gilboa. 1998. Dendritic cell/macrophage precursors capture exogenous antigen for MHC class 1 presentation by dendritic cells. Eur. J. Immunol. 28:1923.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 1923
    • Mitchell, D.A.1    Nair, S.K.2    Gilboa, E.3
  • 41
    • 0030763047 scopus 로고    scopus 로고
    • Presentation of exogenous protein antigens on major histocompatibility complex class I molecules by dendritic cells: Pathway of presentation and regulation by cytokines
    • Brossart, P., and M. J. Bevan. 1997. Presentation of exogenous protein antigens on major histocompatibility complex class I molecules by dendritic cells: pathway of presentation and regulation by cytokines. Blood 90:1594.
    • (1997) Blood , vol.90 , pp. 1594
    • Brossart, P.1    Bevan, M.J.2
  • 42
    • 0033491636 scopus 로고    scopus 로고
    • T lymphocyte tolerance: From thymic deletion to peripheral control mechanisms
    • Stockinger, B. 1999. T lymphocyte tolerance: from thymic deletion to peripheral control mechanisms. Adv. Immunol. 71:229.
    • (1999) Adv. Immunol. , vol.71 , pp. 229
    • Stockinger, B.1
  • 43
    • 0031944607 scopus 로고    scopus 로고
    • CD40 and CD154 in cell-mediated immunity
    • Grewal, I. S., and R. A. Flavell. 1998. CD40 and CD154 in cell-mediated immunity. Annu. Rev. Immunol. 16:111.
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 111
    • Grewal, I.S.1    Flavell, R.A.2
  • 44
    • 0032476602 scopus 로고    scopus 로고
    • CpG-DNA-specinc activation of antigen-presenting cells requires stress kinase activity and is preceded by nonspecific endocytosis and endosomal maturation
    • Hacker, H., H. Mischak, T. Miethke, S. Liptay, R. Schmid, T. Sparwasser, K. Heeg, G. B. Lipford, and H. Wagner. 1998. CpG-DNA-specinc activation of antigen-presenting cells requires stress kinase activity and is preceded by nonspecific endocytosis and endosomal maturation. EMBO J. 17:6230.
    • (1998) EMBO J. , vol.17 , pp. 6230
    • Hacker, H.1    Mischak, H.2    Miethke, T.3    Liptay, S.4    Schmid, R.5    Sparwasser, T.6    Heeg, K.7    Lipford, G.B.8    Wagner, H.9
  • 45
    • 0029620212 scopus 로고
    • Selective activation of c-Jun kinase mitogen-activated protein kinase by CD40 on human B cells
    • Sakata, N., H. R. Patel, N. Terada, A. Aruffo, G. L. Johnson, and E. W. Gelfand. 1995. Selective activation of c-Jun kinase mitogen-activated protein kinase by CD40 on human B cells. J. Biol. Chem. 270:30823.
    • (1995) J. Biol. Chem. , vol.270 , pp. 30823
    • Sakata, N.1    Patel, H.R.2    Terada, N.3    Aruffo, A.4    Johnson, G.L.5    Gelfand, E.W.6
  • 46
    • 0032209664 scopus 로고    scopus 로고
    • Rapid induction of mitogen-activated protein kinases by immune stimulatory CpG DNA
    • Yi, A. K., and A. M. Krieg. 1998. Rapid induction of mitogen-activated protein kinases by immune stimulatory CpG DNA. J. Immunol. 161:4493.
    • (1998) J. Immunol. , vol.161 , pp. 4493
    • Yi, A.K.1    Krieg, A.M.2
  • 49
    • 0031938031 scopus 로고    scopus 로고
    • Enhancement of T cell-independent immune responses in vivo by CD40 antibodies
    • Dullforce, P., D. C. Sulton, and A. W. Heath. 1998. Enhancement of T cell-independent immune responses in vivo by CD40 antibodies. Nat. Med. 4:88.
    • (1998) Nat. Med. , vol.4 , pp. 88
    • Dullforce, P.1    Sulton, D.C.2    Heath, A.W.3
  • 50
    • 0032213323 scopus 로고    scopus 로고
    • CD40 ligand/trimer DNA enhances both humoral and cellular immune responses and induces protective immunity to infectious and tumor challenge
    • Gurunathan, S., K. R. Irvine, C. Y. Wu, J. I. Cohen, E. Thomas, C. Prussia, N. P. Restifo, and R. A. Seder. 1998. CD40 ligand/trimer DNA enhances both humoral and cellular immune responses and induces protective immunity to infectious and tumor challenge. J. Immunol. 161:4563.
    • (1998) J. Immunol. , vol.161 , pp. 4563
    • Gurunathan, S.1    Irvine, K.R.2    Wu, C.Y.3    Cohen, J.I.4    Thomas, E.5    Prussia, C.6    Restifo, N.P.7    Seder, R.A.8
  • 51
    • 0032921241 scopus 로고    scopus 로고
    • CpG-containing oligonucleotides are efficient adjuvants for induction of protective antiviral immune responses with T-cell peptide vaccines
    • Oxenius, A., M. M. Martinic, H. Hengartner, and P. Klenerman. 1999. CpG-containing oligonucleotides are efficient adjuvants for induction of protective antiviral immune responses with T-cell peptide vaccines. J. Virol 73:4120.
    • (1999) J. Virol , vol.73 , pp. 4120
    • Oxenius, A.1    Martinic, M.M.2    Hengartner, H.3    Klenerman, P.4


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