메뉴 건너뛰기




Volumn 28, Issue 5, 2007, Pages 727-734

Weak independent association signals between IDE polymorphisms, Alzheimer's disease and cognitive measures

Author keywords

Alzheimer's disease; Genetic association study; Haplotype; IDE; LD; Mini mental state examination; SNP

Indexed keywords

INSULINASE;

EID: 33847379373     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2006.03.009     Document Type: Article
Times cited : (17)

References (44)
  • 1
    • 0035687018 scopus 로고    scopus 로고
    • Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease
    • Abraham R., Myers A., Wavrant-DeVrieze F., Hamshere M.L., Thomas H.V., Marshall H., et al. Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease. Hum Genet 109 6 (2001) 646-652
    • (2001) Hum Genet , vol.109 , Issue.6 , pp. 646-652
    • Abraham, R.1    Myers, A.2    Wavrant-DeVrieze, F.3    Hamshere, M.L.4    Thomas, H.V.5    Marshall, H.6
  • 2
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: analysis and visualization of LD and haplotype maps
    • Barrett J.C., Fry B., Maller J., and Daly M.J. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21 2 (2005) 263-265
    • (2005) Bioinformatics , vol.21 , Issue.2 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 3
    • 0034704198 scopus 로고    scopus 로고
    • Evidence for genetic linkage of Alzheimer's disease to chromosome 10q
    • Bertram L., Blacker D., Mullin K., Keeney D., Jones J., Basu S., et al. Evidence for genetic linkage of Alzheimer's disease to chromosome 10q. Science 290 (2000) 2302-2303
    • (2000) Science , vol.290 , pp. 2302-2303
    • Bertram, L.1    Blacker, D.2    Mullin, K.3    Keeney, D.4    Jones, J.5    Basu, S.6
  • 4
    • 3242777669 scopus 로고    scopus 로고
    • Insulin-degrading enzyme and Alzheimer disease: a genetic association study in the Han Chinese
    • Bian L., Yang J.D., Guo T.W., Sun Y., Duan S.W., Chen W.Y., et al. Insulin-degrading enzyme and Alzheimer disease: a genetic association study in the Han Chinese. Neurology 63 2 (2004) 241-245
    • (2004) Neurology , vol.63 , Issue.2 , pp. 241-245
    • Bian, L.1    Yang, J.D.2    Guo, T.W.3    Sun, Y.4    Duan, S.W.5    Chen, W.Y.6
  • 7
    • 13844266724 scopus 로고    scopus 로고
    • Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain
    • Blomqvist M.E., Chalmers K., Andreasen N., Bogdanovic N., Wilcock G.K., Cairns N.J., et al. Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain. Neurobiol Aging 26 6 (2005) 795-802
    • (2005) Neurobiol Aging , vol.26 , Issue.6 , pp. 795-802
    • Blomqvist, M.E.1    Chalmers, K.2    Andreasen, N.3    Bogdanovic, N.4    Wilcock, G.K.5    Cairns, N.J.6
  • 8
    • 3042675764 scopus 로고    scopus 로고
    • Sequence variation in the proximity of IDE may impact age at onset of both Parkinson disease and Alzheimer disease
    • Blomqvist M.E., Silburn P.A., Buchanan D.D., Andreasen N., Blennow K., Pedersen N.L., et al. Sequence variation in the proximity of IDE may impact age at onset of both Parkinson disease and Alzheimer disease. Neurogenetics 5 2 (2004) 115-119
    • (2004) Neurogenetics , vol.5 , Issue.2 , pp. 115-119
    • Blomqvist, M.E.1    Silburn, P.A.2    Buchanan, D.D.3    Andreasen, N.4    Blennow, K.5    Pedersen, N.L.6
  • 9
    • 0037162647 scopus 로고    scopus 로고
    • Polymorphisms of insulin degrading enzyme gene are not associated with Alzheimer's disease
    • Boussaha M., Hannequin D., Verpillat P., Brice A., Frebourg T., and Campion D. Polymorphisms of insulin degrading enzyme gene are not associated with Alzheimer's disease. Neurosci Lett 329 1 (2002) 121-123
    • (2002) Neurosci Lett , vol.329 , Issue.1 , pp. 121-123
    • Boussaha, M.1    Hannequin, D.2    Verpillat, P.3    Brice, A.4    Frebourg, T.5    Campion, D.6
  • 10
    • 0027194791 scopus 로고
    • Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
    • Corder E.H., Saunders A.M., Strittmatter W.J., Schmechel D.E., Gaskell P.C., Small G.W., et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261 (1993) 921-923
    • (1993) Science , vol.261 , pp. 921-923
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3    Schmechel, D.E.4    Gaskell, P.C.5    Small, G.W.6
  • 12
    • 0037134505 scopus 로고    scopus 로고
    • Insulin-degrading enzyme rapidly removes the beta-amyloid precursor protein intracellular domain (AICD)
    • Edbauer D., Willem M., Lammich S., Steiner H., and Haass C. Insulin-degrading enzyme rapidly removes the beta-amyloid precursor protein intracellular domain (AICD). J Biol Chem 277 16 (2002) 13389-13393
    • (2002) J Biol Chem , vol.277 , Issue.16 , pp. 13389-13393
    • Edbauer, D.1    Willem, M.2    Lammich, S.3    Steiner, H.4    Haass, C.5
  • 13
    • 0038519618 scopus 로고    scopus 로고
    • Insulin degrading enzyme (IDE) genetic variants and risk of Alzheimer's disease: evidence of effect modification by apolipoprotein E (APOE)
    • Edland S.D., Wavrant-De Vriese F., Compton D., Smith G.E., Ivnik R., Boeve B.F., et al. Insulin degrading enzyme (IDE) genetic variants and risk of Alzheimer's disease: evidence of effect modification by apolipoprotein E (APOE). Neurosci Lett 345 1 (2003) 21-24
    • (2003) Neurosci Lett , vol.345 , Issue.1 , pp. 21-24
    • Edland, S.D.1    Wavrant-De Vriese, F.2    Compton, D.3    Smith, G.E.4    Ivnik, R.5    Boeve, B.F.6
  • 14
    • 1842765688 scopus 로고    scopus 로고
    • Genetic variants in a haplotype block spanning IDE are significantly associated with plasma Abeta42 levels and risk for Alzheimer disease
    • Ertekin-Taner N., Allen M., Fadale D., Scanlin L., Younkin L., Petersen R.C., et al. Genetic variants in a haplotype block spanning IDE are significantly associated with plasma Abeta42 levels and risk for Alzheimer disease. Hum Mutat 23 4 (2004) 334-342
    • (2004) Hum Mutat , vol.23 , Issue.4 , pp. 334-342
    • Ertekin-Taner, N.1    Allen, M.2    Fadale, D.3    Scanlin, L.4    Younkin, L.5    Petersen, R.C.6
  • 15
    • 0034703979 scopus 로고    scopus 로고
    • Linkage of plasma Ab42 to a quantitative locus on chromosome 10 in late onset Alzheimer's disease pedigrees
    • Ertekin-Taner N., Graff-Radford N., Younkin L., Eckerman C., Baker M., Adamson J., et al. Linkage of plasma Ab42 to a quantitative locus on chromosome 10 in late onset Alzheimer's disease pedigrees. Science 290 (2000) 2303-2304
    • (2000) Science , vol.290 , pp. 2303-2304
    • Ertekin-Taner, N.1    Graff-Radford, N.2    Younkin, L.3    Eckerman, C.4    Baker, M.5    Adamson, J.6
  • 16
    • 13544273507 scopus 로고    scopus 로고
    • Elevated amyloid β protein (Aβ42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene
    • Ertekin-Taner N., Ronald J., Feuk L., Prince J., Tucker M., Younkin L., et al. Elevated amyloid β protein (Aβ42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene. Hum Mol Genet 14 3 (2005) 447-460
    • (2005) Hum Mol Genet , vol.14 , Issue.3 , pp. 447-460
    • Ertekin-Taner, N.1    Ronald, J.2    Feuk, L.3    Prince, J.4    Tucker, M.5    Younkin, L.6
  • 17
    • 0030823158 scopus 로고    scopus 로고
    • Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer's disease. A meta-analysis
    • Farrer L.A., Cupples L.A., Haines J.L., Hyman B., Kukull W.A., Mayeux R., et al. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer's disease. A meta-analysis. JAMA 278 (1997) 1349-1356
    • (1997) JAMA , vol.278 , pp. 1349-1356
    • Farrer, L.A.1    Cupples, L.A.2    Haines, J.L.3    Hyman, B.4    Kukull, W.A.5    Mayeux, R.6
  • 18
    • 0037390039 scopus 로고    scopus 로고
    • Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo
    • Farris W., Mansourian S., Chang Y., Lindsley L., Eckman E.A., Frosch M.P., et al. Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo. Proc Natl Acad Sci USA 100 7 (2003) 4162-4167
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.7 , pp. 4162-4167
    • Farris, W.1    Mansourian, S.2    Chang, Y.3    Lindsley, L.4    Eckman, E.A.5    Frosch, M.P.6
  • 19
    • 1642290835 scopus 로고    scopus 로고
    • Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein
    • Farris W., Mansourian S., Leissring M.A., Eckman E.A., Bertram L., Eckman C.B., et al. Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein. Am J Pathol 164 4 (2004) 1425-1434
    • (2004) Am J Pathol , vol.164 , Issue.4 , pp. 1425-1434
    • Farris, W.1    Mansourian, S.2    Leissring, M.A.3    Eckman, E.A.4    Bertram, L.5    Eckman, C.B.6
  • 20
    • 0016823810 scopus 로고
    • 'Mini Mental State'. A practical method for grading the cognitive state of patients for the clinician
    • Folstein M.F., Folstein S.E., and McHugh P.R. 'Mini Mental State'. A practical method for grading the cognitive state of patients for the clinician. J Psychiat Res 12 (1975) 189-198
    • (1975) J Psychiat Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 21
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
    • Hardy J., and Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297 5580 (2002) 353-356
    • (2002) Science , vol.297 , Issue.5580 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 24
    • 0346101885 scopus 로고    scopus 로고
    • Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death
    • Leissring M.A., Farris W., Chang A.Y., Walsh D.M., Wu X., Sun X., et al. Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death. Neuron 40 6 (2003) 1087-1093
    • (2003) Neuron , vol.40 , Issue.6 , pp. 1087-1093
    • Leissring, M.A.1    Farris, W.2    Chang, A.Y.3    Walsh, D.M.4    Wu, X.5    Sun, X.6
  • 25
    • 0037312921 scopus 로고    scopus 로고
    • Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
    • Lohmueller K.E., Pearce C.L., Pike M., Lander E.S., and Hirschhorn J.N. Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 33 2 (2003) 177-182
    • (2003) Nat Genet , vol.33 , Issue.2 , pp. 177-182
    • Lohmueller, K.E.1    Pearce, C.L.2    Pike, M.3    Lander, E.S.4    Hirschhorn, J.N.5
  • 26
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G., Folstein M., Katzman R., Price D., and Stadlan E.M. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34 (1984) 939-944
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Folstein, M.2    Katzman, R.3    Price, D.4    Stadlan, E.M.5
  • 27
    • 0037947406 scopus 로고    scopus 로고
    • Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo
    • Miller B.C., Eckman E.A., Sambamurti K., Dobbs N., Chow K.M., Eckman C.B., et al. Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo. Proc Natl Acad Sci USA 100 10 (2003) 6221-6226
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.10 , pp. 6221-6226
    • Miller, B.C.1    Eckman, E.A.2    Sambamurti, K.3    Dobbs, N.4    Chow, K.M.5    Eckman, C.B.6
  • 28
    • 13844253254 scopus 로고    scopus 로고
    • Linkage disequilibrium patterns and tagSNP transferability among European populations
    • Mueller J.C., Lohmussaar E., Magi R., Remm M., Bettecken T., Lichtner P., et al. Linkage disequilibrium patterns and tagSNP transferability among European populations. Am J Hum Genet 76 3 (2005) 387-398
    • (2005) Am J Hum Genet , vol.76 , Issue.3 , pp. 387-398
    • Mueller, J.C.1    Lohmussaar, E.2    Magi, R.3    Remm, M.4    Bettecken, T.5    Lichtner, P.6
  • 29
    • 0034551718 scopus 로고    scopus 로고
    • Insulysin hydrolyzes amyloid beta peptides to products that are neither neurotoxic nor deposit on amyloid plaques
    • Mukherjee A., Song E., Kihiko-Ehmann M., Goodman Jr. J.P., Pyrek J.S., Estus S., et al. Insulysin hydrolyzes amyloid beta peptides to products that are neither neurotoxic nor deposit on amyloid plaques. J Neurosci 20 23 (2000) 8745-8749
    • (2000) J Neurosci , vol.20 , Issue.23 , pp. 8745-8749
    • Mukherjee, A.1    Song, E.2    Kihiko-Ehmann, M.3    Goodman Jr., J.P.4    Pyrek, J.S.5    Estus, S.6
  • 31
    • 0034704197 scopus 로고    scopus 로고
    • Susceptibility locus for Alzheimer's disease on chromosome 10
    • Myers A., Holmans P., Marshall H., Kwon J., Meyer D., Ramic D., et al. Susceptibility locus for Alzheimer's disease on chromosome 10. Science 290 (2000) 2304-2305
    • (2000) Science , vol.290 , pp. 2304-2305
    • Myers, A.1    Holmans, P.2    Marshall, H.3    Kwon, J.4    Meyer, D.5    Ramic, D.6
  • 32
    • 4143134235 scopus 로고    scopus 로고
    • The future of association studies: gene-based analysis and replication
    • Neale B.M., and Sham P.C. The future of association studies: gene-based analysis and replication. Am J Hum Genet 75 3 (2004) 353-362
    • (2004) Am J Hum Genet , vol.75 , Issue.3 , pp. 353-362
    • Neale, B.M.1    Sham, P.C.2
  • 35
    • 0242321663 scopus 로고    scopus 로고
    • Genetic variation in a haplotype block spanning IDE influences Alzheimer disease
    • Prince J.A., Feuk L., Gu H.F., Johansson B., Gatz M., Blennow K., et al. Genetic variation in a haplotype block spanning IDE influences Alzheimer disease. Hum Mutat 22 5 (2003) 363-371
    • (2003) Hum Mutat , vol.22 , Issue.5 , pp. 363-371
    • Prince, J.A.1    Feuk, L.2    Gu, H.F.3    Johansson, B.4    Gatz, M.5    Blennow, K.6
  • 36
    • 0036844521 scopus 로고    scopus 로고
    • Partition-ligation-expectation-maximization algorithm for haplotype inference with single-nucleotide polymorphisms
    • Qin Z.S., Niu T., and Liu J.S. Partition-ligation-expectation-maximization algorithm for haplotype inference with single-nucleotide polymorphisms. Am J Hum Genet 71 5 (2002) 1242-1247
    • (2002) Am J Hum Genet , vol.71 , Issue.5 , pp. 1242-1247
    • Qin, Z.S.1    Niu, T.2    Liu, J.S.3
  • 37
    • 0000398342 scopus 로고    scopus 로고
    • Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation
    • Qiu W.Q., Walsh D.M., Ye Z., Vekrellis K., Zhang J., Podlisny M.B., et al. Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation. J Biol Chem 273 49 (1998) 32730-32738
    • (1998) J Biol Chem , vol.273 , Issue.49 , pp. 32730-32738
    • Qiu, W.Q.1    Walsh, D.M.2    Ye, Z.3    Vekrellis, K.4    Zhang, J.5    Podlisny, M.B.6
  • 38
    • 0023037928 scopus 로고
    • CAMDEX. A standardized instrument for the diagnosis of mental disorder in the elderly with special reference to the early detection of dementia
    • Roth M., Tym E., Mountjoy C.Q., Huppert F.A., Hendrie H., Verma S., et al. CAMDEX. A standardized instrument for the diagnosis of mental disorder in the elderly with special reference to the early detection of dementia. Br J Psychiat 149 (1986) 698-709
    • (1986) Br J Psychiat , vol.149 , pp. 698-709
    • Roth, M.1    Tym, E.2    Mountjoy, C.Q.3    Huppert, F.A.4    Hendrie, H.5    Verma, S.6
  • 39
    • 0942290670 scopus 로고    scopus 로고
    • No association between the insulin degrading enzyme gene and Alzheimer's disease in a Japanese population
    • Sakai A., Ujike H., Nakata K., Takehisa Y., Imamura T., Uchida N., et al. No association between the insulin degrading enzyme gene and Alzheimer's disease in a Japanese population. Am J Med Genet B Neuropsychiat Genet 125 1 (2004) 87-91
    • (2004) Am J Med Genet B Neuropsychiat Genet , vol.125 , Issue.1 , pp. 87-91
    • Sakai, A.1    Ujike, H.2    Nakata, K.3    Takehisa, Y.4    Imamura, T.5    Uchida, N.6
  • 40
    • 0027337858 scopus 로고
    • Apolipoprotin E e4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases
    • Saunders A.M., Schmader K., Breitner J.C.S., Benson M.D., Brown W.T., Goldfarb L., et al. Apolipoprotin E e4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases. Lancet 342 (1993) 710-711
    • (1993) Lancet , Issue.342 , pp. 710-711
    • Saunders, A.M.1    Schmader, K.2    Breitner, J.C.S.3    Benson, M.D.4    Brown, W.T.5    Goldfarb, L.6
  • 41
    • 0034161516 scopus 로고    scopus 로고
    • Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme
    • Vekrellis K., Ye Z., Qiu W.Q., Walsh D., Hartley D., Chesneau V., et al. Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme. J Neurosci 20 5 (2000) 1657-1665
    • (2000) J Neurosci , vol.20 , Issue.5 , pp. 1657-1665
    • Vekrellis, K.1    Ye, Z.2    Qiu, W.Q.3    Walsh, D.4    Hartley, D.5    Chesneau, V.6
  • 42
    • 0028285127 scopus 로고
    • The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part V. A normative study of the neuropsychological battery
    • Welsh K.A., Butters N., Mohs R.C., Beekly D., Edland S., Fillenbaum G., et al. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part V. A normative study of the neuropsychological battery. Neurology 44 (1994) 609-614
    • (1994) Neurology , vol.44 , pp. 609-614
    • Welsh, K.A.1    Butters, N.2    Mohs, R.C.3    Beekly, D.4    Edland, S.5    Fillenbaum, G.6
  • 43
    • 0036284203 scopus 로고    scopus 로고
    • Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals
    • Zaykin D.V., Westfall P.H., Young S.S., Karnoub M.A., Wagner M.J., and Ehm M.G. Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals. Hum Hered 53 2 (2002) 79-91
    • (2002) Hum Hered , vol.53 , Issue.2 , pp. 79-91
    • Zaykin, D.V.1    Westfall, P.H.2    Young, S.S.3    Karnoub, M.A.4    Wagner, M.J.5    Ehm, M.G.6
  • 44
    • 0030870822 scopus 로고    scopus 로고
    • Improved method for genotyping apolipoprotein E polymorphisms by a PCR-based assay simultaneously utilizing two distinct restriction enzymes
    • Zivelin A., Rosenberg N., Peretz H., Amit Y., Kornbrot N., and Seligsohn U. Improved method for genotyping apolipoprotein E polymorphisms by a PCR-based assay simultaneously utilizing two distinct restriction enzymes. Clin Chem 43 (1997) 1657-1659
    • (1997) Clin Chem , vol.43 , pp. 1657-1659
    • Zivelin, A.1    Rosenberg, N.2    Peretz, H.3    Amit, Y.4    Kornbrot, N.5    Seligsohn, U.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.