-
1
-
-
0035687018
-
Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease
-
Abraham R, Myers A, Wavrant-DeVrieze F, Hamshere ML, Thomas HV, Marshall H, Compton D, Spurlock G, Turic D, Hoogendoorn B, Kwon JM, Petersen RC, Tangalos E, Norton J, Morris JC, Bullock R, Liolitsa D, Lovestone S, Hardy J, Goate A, O'Donovan M, Williams J, Owen MJ, Jones L. 2001. Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease. Hum Genet 109(6):646-652.
-
(2001)
Hum Genet
, vol.109
, Issue.6
, pp. 646-652
-
-
Abraham, R.1
Myers, A.2
Wavrant-DeVrieze, F.3
Hamshere, M.L.4
Thomas, H.V.5
Marshall, H.6
Compton, D.7
Spurlock, G.8
Turic, D.9
Hoogendoorn, B.10
Kwon, J.M.11
Petersen, R.C.12
Tangalos, E.13
Norton, J.14
Morris, J.C.15
Bullock, R.16
Liolitsa, D.17
Lovestone, S.18
Hardy, J.19
Goate, A.20
O'Donovan, M.21
Williams, J.22
Owen, M.J.23
Jones, L.24
more..
-
2
-
-
0037036168
-
Confirmation of association between D10S583 and Alzheimer's disease in a case-control sample
-
Ait-Ghezala G, Abdullah L, Crescentini R, Crawford F, Town T, Singh S, Richards D, Duara R, Mullan M. 2002. Confirmation of association between D10S583 and Alzheimer's disease in a case-control sample. Neurosci Lett 325(2):87-90.
-
(2002)
Neurosci Lett
, vol.325
, Issue.2
, pp. 87-90
-
-
Ait-Ghezala, G.1
Abdullah, L.2
Crescentini, R.3
Crawford, F.4
Town, T.5
Singh, S.6
Richards, D.7
Duara, R.8
Mullan, M.9
-
3
-
-
0029811040
-
Association of insulin-degrading enzyme with a 70 kDa cytosolic protein in hepatoma cells
-
Authier F, Cameron PH, Taupin V. 1996. Association of insulin-degrading enzyme with a 70 kDa cytosolic protein in hepatoma cells. Biochem J 319(Pt 1):149-158.
-
(1996)
Biochem J
, vol.319
, Issue.PART 1
, pp. 149-158
-
-
Authier, F.1
Cameron, P.H.2
Taupin, V.3
-
4
-
-
0034704198
-
Evidence for genetic linkage of Alzheimer's disease to chromosome 10q
-
Bertram L, Blacker D, Mullin K, Keeney D, Jones J, Basu S, Yhu S, McInnis MG, Go RC, Vekrellis K, Selkoe DJ, Saunders AJ, Tanzi RE. 2000. Evidence for genetic linkage of Alzheimer's disease to chromosome 10q. Science 290(5500):2302-2303.
-
(2000)
Science
, vol.290
, Issue.5500
, pp. 2302-2303
-
-
Bertram, L.1
Blacker, D.2
Mullin, K.3
Keeney, D.4
Jones, J.5
Basu, S.6
Yhu, S.7
McInnis, M.G.8
Go, R.C.9
Vekrellis, K.10
Selkoe, D.J.11
Saunders, A.J.12
Tanzi, R.E.13
-
5
-
-
0037162647
-
Polymorphisms of insulin degrading enzyme gene are not associated with Alzheimer's disease
-
Boussaha M, Hannequin D, Verpillat P, Brice A, Frebourg T, Campion D. 2002. Polymorphisms of insulin degrading enzyme gene are not associated with Alzheimer's disease. Neurosci Lett 329(1):121-123.
-
(2002)
Neurosci Lett
, vol.329
, Issue.1
, pp. 121-123
-
-
Boussaha, M.1
Hannequin, D.2
Verpillat, P.3
Brice, A.4
Frebourg, T.5
Campion, D.6
-
6
-
-
0030787591
-
Insulin-degrading enzyme does not require peroxisomal localization for insulin degradation
-
Chesneau V, Perlman RK, Li W, Keller GA, Rosner MR. 1997. Insulin-degrading enzyme does not require peroxisomal localization for insulin degradation. Endocrinology 138(8):3444-3451.
-
(1997)
Endocrinology
, vol.138
, Issue.8
, pp. 3444-3451
-
-
Chesneau, V.1
Perlman, R.K.2
Li, W.3
Keller, G.A.4
Rosner, M.R.5
-
7
-
-
0034667518
-
Purified recombinant insulin-degrading enzyme degrades amyloid beta-protein but does not promote its oligomerization
-
Chesneau V, Vekrellis K, Rosner MR, Selkoe DJ. 2000. Purified recombinant insulin-degrading enzyme degrades amyloid beta-protein but does not promote its oligomerization. Biochem J 351(Pt 2):509-516.
-
(2000)
Biochem J
, vol.351
, Issue.PART 2
, pp. 509-516
-
-
Chesneau, V.1
Vekrellis, K.2
Rosner, M.R.3
Selkoe, D.J.4
-
8
-
-
0037219221
-
Reduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon4 allele
-
Cook DG, Leverenz JB, McMillan PJ, Kulstad JJ, Ericksen S, Roth RA, Schellenberg GD, Jin LW, Kovacina KS, Craft S. 2003. Reduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon4 allele. Am J Pathol 162(1):313-319.
-
(2003)
Am J Pathol
, vol.162
, Issue.1
, pp. 313-319
-
-
Cook, D.G.1
Leverenz, J.B.2
McMillan, P.J.3
Kulstad, J.J.4
Ericksen, S.5
Roth, R.A.6
Schellenberg, G.D.7
Jin, L.W.8
Kovacina, K.S.9
Craft, S.10
-
9
-
-
0037134505
-
Insulin-degrading enzyme rapidly removes the beta-amyloid precursor protein intracellular domain (AICD)
-
Edbauer D, Willem M, Lammich S, Steiner H, Haass C. 2002. Insulin-degrading enzyme rapidly removes the beta-amyloid precursor protein intracellular domain (AICD). J Biol Chem 277(16):13389-13393.
-
(2002)
J Biol Chem
, vol.277
, Issue.16
, pp. 13389-13393
-
-
Edbauer, D.1
Willem, M.2
Lammich, S.3
Steiner, H.4
Haass, C.5
-
10
-
-
0034703979
-
Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees
-
Ertekin-Taner N, Graff-Radford N, Younkin LH, Eckman C, Baker M, Adamson J, Ronald J, Blangero J, Hutton M, Younkin SG. 2000. Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees. Science 290(5500):2303-2304.
-
(2000)
Science
, vol.290
, Issue.5500
, pp. 2303-2304
-
-
Ertekin-Taner, N.1
Graff-Radford, N.2
Younkin, L.H.3
Eckman, C.4
Baker, M.5
Adamson, J.6
Ronald, J.7
Blangero, J.8
Hutton, M.9
Younkin, S.G.10
-
11
-
-
0027964969
-
Inducible expression and cellular localization of insulin-degrading enzyme in a stably transfected cell line
-
Kuo WL, Gehm BD, Rosner MR, Li W, Keller G. 1994. Inducible expression and cellular localization of insulin-degrading enzyme in a stably transfected cell line. J Biol Chem 269(36):22599-22606.
-
(1994)
J Biol Chem
, vol.269
, Issue.36
, pp. 22599-22606
-
-
Kuo, W.L.1
Gehm, B.D.2
Rosner, M.R.3
Li, W.4
Keller, G.5
-
12
-
-
0034704197
-
Susceptibility locus for Alzheimer's disease on chromosome 10
-
Myers A, Holmans P, Marshall H, Kwon J, Meyer D, Ramic D, Shears S, Booth J, DeVrieze FW, Crook R, Hamshere M, Abraham R, Tunstall N, Rice F, Carty S, Lillystone S, Kehoe P, Rudrasingham V, Jones L, Lovestone S, Perez-Tur J, Williams J, Owen MJ, Hardy J, Goate AM. 2000. Susceptibility locus for Alzheimer's disease on chromosome 10. Science 290(5500):2304-2305.
-
(2000)
Science
, vol.290
, Issue.5500
, pp. 2304-2305
-
-
Myers, A.1
Holmans, P.2
Marshall, H.3
Kwon, J.4
Meyer, D.5
Ramic, D.6
Shears, S.7
Booth, J.8
DeVrieze, F.W.9
Crook, R.10
Hamshere, M.11
Abraham, R.12
Tunstall, N.13
Rice, F.14
Carty, S.15
Lillystone, S.16
Kehoe, P.17
Rudrasingham, V.18
Jones, L.19
Lovestone, S.20
Perez-Tur, J.21
Williams, J.22
Owen, M.J.23
Hardy, J.24
Goate, A.M.25
more..
-
13
-
-
0000398342
-
Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation
-
Qiu WQ, Walsh DM, Ye Z, Vekrellis K, Zhang J, Podlisny MB, Rosner MR, Safavi A, Hersh LB, Selkoe DJ. 1998. Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation. J Biol Chem 273(49):32730-32738.
-
(1998)
J Biol Chem
, vol.273
, Issue.49
, pp. 32730-32738
-
-
Qiu, W.Q.1
Walsh, D.M.2
Ye, Z.3
Vekrellis, K.4
Zhang, J.5
Podlisny, M.B.6
Rosner, M.R.7
Safavi, A.8
Hersh, L.B.9
Selkoe, D.J.10
-
14
-
-
0028909113
-
Monte Carlo test for association between disease and alleles at highly polymorphic loci
-
Sham PC, Curtis D. 1995. Monte Carlo test for association between disease and alleles at highly polymorphic loci. Ann Hum Genet 59:97-105.
-
(1995)
Ann Hum Genet
, vol.59
, pp. 97-105
-
-
Sham, P.C.1
Curtis, D.2
-
15
-
-
0037192120
-
Differential effects of proteases involved in intracellular degradation of amyloid beta-protein between detergent-soluble and -insoluble pools in CHO-695 cells
-
Sudoh S, Frosch MP, Wolf BA. 2002. Differential effects of proteases involved in intracellular degradation of amyloid beta-protein between detergent-soluble and -insoluble pools in CHO-695 cells. Biochemistry 41(4):1091-1099.
-
(2002)
Biochemistry
, vol.41
, Issue.4
, pp. 1091-1099
-
-
Sudoh, S.1
Frosch, M.P.2
Wolf, B.A.3
-
16
-
-
0033595706
-
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
Vassar R, Bennett BD, Babu-Khan S, Kahn S, Mendiaz EA, Denis P, Teplow DB, Ross S, Amarante P, Loeloff R, Luo Y, Fisher S, Fuller J, Edenson S, Lile J, Jarosinski MA, Biere AL, Curran E, Burgess T, Louis JC, Collins F, Treanor J, Rogers G, Citron M. 1999. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science 286(5440):73.
-
(1999)
Science
, vol.286
, Issue.5440
, pp. 73
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Kahn, S.4
Mendiaz, E.A.5
Denis, P.6
Teplow, D.B.7
Ross, S.8
Amarante, P.9
Loeloff, R.10
Luo, Y.11
Fisher, S.12
Fuller, J.13
Edenson, S.14
Lile, J.15
Jarosinski, M.A.16
Biere, A.L.17
Curran, E.18
Burgess, T.19
Louis, J.C.20
Collins, F.21
Treanor, J.22
Rogers, G.23
Citron, M.24
more..
-
17
-
-
0034161516
-
Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme
-
Vekrellis K, Ye Z, Qiu WQ, Walsh D, Hartley D, Chesneau V, Rosner MR, Selkoe DJ. 2000. Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme. J Neurosci 20(5):1657-1665.
-
(2000)
J Neurosci
, vol.20
, Issue.5
, pp. 1657-1665
-
-
Vekrellis, K.1
Ye, Z.2
Qiu, W.Q.3
Walsh, D.4
Hartley, D.5
Chesneau, V.6
Rosner, M.R.7
Selkoe, D.J.8
-
18
-
-
0025801744
-
Apolipoprotein E genotyping by one-stage PCR
-
Wenham PR, Price WH, Blandell G. 1991. Apolipoprotein E genotyping by one-stage PCR. Luncet 337:1158-1159.
-
(1991)
Luncet
, vol.337
, pp. 1158-1159
-
-
Wenham, P.R.1
Price, W.H.2
Blandell, G.3
-
19
-
-
0001200144
-
Testing linkage disequilibrium between a disease gene and marker loci
-
Xie X, Ott J. 1993. Testing linkage disequilibrium between a disease gene and marker loci. Am J Hum Genet 53:A1107.
-
(1993)
Am J Hum Genet
, vol.53
-
-
Xie, X.1
Ott, J.2
|