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Volumn 28, Issue 2, 2007, Pages 404-413

The Akt inhibitor deguelin, is an angiopreventive agent also acting on the NF-κB pathway

Author keywords

[No Author keywords available]

Indexed keywords

DEGUELIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; METALLOPROTEINASE; PLACEBO; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; PROTEIN P21; PROTEIN P53; SURVIVIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 33847259309     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgl162     Document Type: Article
Times cited : (66)

References (60)
  • 1
    • 0033980370 scopus 로고    scopus 로고
    • Progress in cancer chemoprevention: Development of diet-derived chemopreventive agents
    • Kelloff,G.J., Crowell,J.A., Steele,V.E. et al. (2000) Progress in cancer chemoprevention: Development of diet-derived chemopreventive agents. J. Nutr., 130, 467S-471S.
    • (2000) J. Nutr. , vol.130
    • Kelloff, G.J.1    Crowell, J.A.2    Steele, V.E.3
  • 2
    • 0031012054 scopus 로고    scopus 로고
    • Plant-derived anticancer agents
    • Pezzuto,J.M. (1997) Plant-derived anticancer agents. Biochem. Pharmacol., 53, 121-133.
    • (1997) Biochem. Pharmacol. , vol.53 , pp. 121-133
    • Pezzuto, J.M.1
  • 4
    • 27944452718 scopus 로고    scopus 로고
    • Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis
    • Lee,H.Y., Oh,S.H., Woo,J.K. et al. (2005) Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis. J. Natl. Cancer Inst., 97, 1695-1699.
    • (2005) J. Natl. Cancer Inst. , vol.97 , pp. 1695-1699
    • Lee, H.Y.1    Oh, S.H.2    Woo, J.K.3
  • 6
    • 0037430197 scopus 로고    scopus 로고
    • Deguelin suppresses the formation of carcinogen-induced aberrant crypt foci in the colon of CF-1 mice
    • Murillo,G., Kosmeder,J.W.II, Pezzuto,J.M. and Mehta,R.G. (2003) Deguelin suppresses the formation of carcinogen-induced aberrant crypt foci in the colon of CF-1 mice. Int. J. Cancer, 104, 7-11.
    • (2003) Int. J. Cancer , vol.104 , pp. 7-11
    • Murillo, G.1    Kosmeder II, J.W.2    Pezzuto, J.M.3    Mehta, R.G.4
  • 8
    • 0036892114 scopus 로고    scopus 로고
    • Deguelin inhibits the growth of colon cancer cells through the induction of apoptosis and cell cycle arrest
    • Murillo,G., Salti,G.I., Kosmeder,J.W.II, Pezzuto,J.M. and Mehta,R.G. (2002) Deguelin inhibits the growth of colon cancer cells through the induction of apoptosis and cell cycle arrest. Eur. J. Cancer, 38, 2446-2454.
    • (2002) Eur. J. Cancer , vol.38 , pp. 2446-2454
    • Murillo, G.1    Salti, G.I.2    Kosmeder II, J.W.3    Pezzuto, J.M.4    Mehta, R.G.5
  • 9
    • 2442669734 scopus 로고    scopus 로고
    • Apoptosis induction by the natural product cancer chemopreventive agent deguelin is mediated through the inhibition of mitochondrial bioenergetics
    • Hail,N.Jr and Lotan,R. (2004) Apoptosis induction by the natural product cancer chemopreventive agent deguelin is mediated through the inhibition of mitochondrial bioenergetics. Apoptosis, 9, 437-447.
    • (2004) Apoptosis , vol.9 , pp. 437-447
    • Hail Jr., N.1    Lotan, R.2
  • 10
    • 1042278720 scopus 로고    scopus 로고
    • Deguelin-induced inhibition of cyclooxygenase-2 expression in human bronchial epithelial cells
    • Lee,H.Y., Suh,Y.A., Kosmeder,J.W., Pezzuto,J.M., Hong,W.K. and Kurie,J.M. (2004) Deguelin-induced inhibition of cyclooxygenase-2 expression in human bronchial epithelial cells. Clin. Cancer Res., 10, 1074-1079.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 1074-1079
    • Lee, H.Y.1    Suh, Y.A.2    Kosmeder, J.W.3    Pezzuto, J.M.4    Hong, W.K.5    Kurie, J.M.6
  • 11
    • 0037453909 scopus 로고    scopus 로고
    • Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells
    • Chun,K.H., Kosmeder,J.W.II, Sun,S., Pezzuto,J.M., Lotan,R., Hong,W.K. and Lee,H.Y. (2003) Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells. J. Natl Cancer Inst., 95, 291-302.
    • (2003) J. Natl Cancer Inst. , vol.95 , pp. 291-302
    • Chun, K.H.1    Kosmeder II, J.W.2    Sun, S.3    Pezzuto, J.M.4    Lotan, R.5    Hong, W.K.6    Lee, H.Y.7
  • 12
    • 0036136731 scopus 로고    scopus 로고
    • 'Angioprevention': Angiogenesis is a common and key target for cancer chemopreventive agents
    • Tosetti,F., Ferrari,N., De Flora,S. and Albini,A. (2002) 'Angioprevention': Angiogenesis is a common and key target for cancer chemopreventive agents. FASEB J., 16, 2-14.
    • (2002) FASEB J. , vol.16 , pp. 2-14
    • Tosetti, F.1    Ferrari, N.2    De Flora, S.3    Albini, A.4
  • 13
    • 0032750920 scopus 로고    scopus 로고
    • Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing
    • Jones,M.K., Wang,H., Peskar,B.M., Levin,E., Itani,R.M., Sarfeh,I.J. and Tarnawski,A.S. (1999) Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing. Nat. Med., 5, 1418-1423.
    • (1999) Nat. Med. , vol.5 , pp. 1418-1423
    • Jones, M.K.1    Wang, H.2    Peskar, B.M.3    Levin, E.4    Itani, R.M.5    Sarfeh, I.J.6    Tarnawski, A.S.7
  • 17
    • 0037188941 scopus 로고    scopus 로고
    • Role of Akt signaling in vascular homeostasis and angiogenesis
    • Shiojima,I. and Walsh,K. (2002) Role of Akt signaling in vascular homeostasis and angiogenesis. Circ. Res., 90, 1243-1250.
    • (2002) Circ. Res. , vol.90 , pp. 1243-1250
    • Shiojima, I.1    Walsh, K.2
  • 18
    • 23644446866 scopus 로고    scopus 로고
    • Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis
    • Ackah,E., Yu,J., Zoellner,S. et al. (2005) Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis. J. Clin. Invest., 115, 2119-2127.
    • (2005) J. Clin. Invest. , vol.115 , pp. 2119-2127
    • Ackah, E.1    Yu, J.2    Zoellner, S.3
  • 19
  • 20
    • 33645814383 scopus 로고    scopus 로고
    • Mechanisms of the antiangiogenic activity by the hop flavonoid xanthohumol: NF-κB and Akt as targets
    • Albini,A., Dell'eva,R., Vene,R., Ferrari,N., Buhler,D.R., Noonan,D.M. and Fassina,G. (2005) Mechanisms of the antiangiogenic activity by the hop flavonoid xanthohumol: NF-κB and Akt as targets. FASEB J., 20, 527-529.
    • (2005) FASEB J. , vol.20 , pp. 527-529
    • Albini, A.1    Dell'eva, R.2    Vene, R.3    Ferrari, N.4    Buhler, D.R.5    Noonan, D.M.6    Fassina, G.7
  • 21
    • 8244221004 scopus 로고    scopus 로고
    • The beta-core fragment of human Chorionic Gonadotrophin (hCG) inhibits growth of Kaposi's sarcoma-derived cells and a new immortalized Kaposi's sarcoma cell line
    • Albini,A., Paglieri,I., Orengo,G. et al. (1997) The beta-core fragment of human Chorionic Gonadotrophin (hCG) inhibits growth of Kaposi's sarcoma-derived cells and a new immortalized Kaposi's sarcoma cell line. AIDS, 11, 713-721.
    • (1997) AIDS , vol.11 , pp. 713-721
    • Albini, A.1    Paglieri, I.2    Orengo, G.3
  • 23
    • 0028905092 scopus 로고
    • Inhibition of invasion, gelatinase activity, tumor take and metastasis of malignant cells by N-acetylcysteine
    • Albini,A., D'Agostini,F., Giunciuglio,D., Paglieri,J., Balansky,R.M. and De Flora,S. (1995) Inhibition of invasion, gelatinase activity, tumor take and metastasis of malignant cells by N-acetylcysteine. Int. J. Cancer, 61, 121-129.
    • (1995) Int. J. Cancer , vol.61 , pp. 121-129
    • Albini, A.1    D'Agostini, F.2    Giunciuglio, D.3    Paglieri, J.4    Balansky, R.M.5    De Flora, S.6
  • 24
    • 0027981273 scopus 로고
    • Angiogenic potential in vivo by Kaposi sarcoma cell-free supernatants and HIV1-tat product: Inhibition of KS-like lesions by TIMP-2
    • Albini,A., Fontanini,G., Masiello,L., Tacchetti,C., Bigini,D., Luzzi,P., Noonan,D.M. and Stetler-Stevenson,W.G. (1994) Angiogenic potential in vivo by Kaposi sarcoma cell-free supernatants and HIV1-tat product: inhibition of KS-like lesions by TIMP-2. AIDS, 8, 1237-1244.
    • (1994) AIDS , vol.8 , pp. 1237-1244
    • Albini, A.1    Fontanini, G.2    Masiello, L.3    Tacchetti, C.4    Bigini, D.5    Luzzi, P.6    Noonan, D.M.7    Stetler-Stevenson, W.G.8
  • 25
    • 0036281211 scopus 로고    scopus 로고
    • Processing of gene expression data generated by quantitative real-time RT-PCR
    • 1372-1374, 1376
    • Muller,P.Y., Janovjak,H., Miserez,A.R. and Dobbie,Z. (2002) Processing of gene expression data generated by quantitative real-time RT-PCR. Biotechniques, 32, 1372-1374, 1376, 1378-1379.
    • (2002) Biotechniques , vol.32 , pp. 1378-1379
    • Muller, P.Y.1    Janovjak, H.2    Miserez, A.R.3    Dobbie, Z.4
  • 27
    • 16844382968 scopus 로고    scopus 로고
    • Signaling intricacies take center stage in cancer cells
    • Kumar,R. and Hung,M.C. (2005) Signaling intricacies take center stage in cancer cells. Cancer Res., 65, 2511-2515.
    • (2005) Cancer Res. , vol.65 , pp. 2511-2515
    • Kumar, R.1    Hung, M.C.2
  • 29
    • 0033517189 scopus 로고    scopus 로고
    • NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase
    • Ozes,O.N., Mayo,L.D., Gustin,J.A., Pfeffer,S.R., Pfeffer,L.M. and Donner,D.B. (1999) NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature, 401, 82-85.
    • (1999) Nature , vol.401 , pp. 82-85
    • Ozes, O.N.1    Mayo, L.D.2    Gustin, J.A.3    Pfeffer, S.R.4    Pfeffer, L.M.5    Donner, D.B.6
  • 30
    • 27144477415 scopus 로고    scopus 로고
    • Activated AKT regulates NF-kappaB activation, p53 inhibition and cell survival in HTLV-1-transformed cells
    • Jeong,S.J., Pise-Masison,C.A., Radonovich,M.F., Park,H.U. and Brady,J.N. (2005) Activated AKT regulates NF-kappaB activation, p53 inhibition and cell survival in HTLV-1-transformed cells. Oncogene, 24, 6719-6728.
    • (2005) Oncogene , vol.24 , pp. 6719-6728
    • Jeong, S.J.1    Pise-Masison, C.A.2    Radonovich, M.F.3    Park, H.U.4    Brady, J.N.5
  • 31
    • 0035849720 scopus 로고    scopus 로고
    • Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis
    • Huang,S., Pettaway,C.A., Uehara,H., Bucana,C.D. and Fidler,I.J. (2001) Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis. Oncogene, 20, 4188-4197.
    • (2001) Oncogene , vol.20 , pp. 4188-4197
    • Huang, S.1    Pettaway, C.A.2    Uehara, H.3    Bucana, C.D.4    Fidler, I.J.5
  • 32
    • 0037443760 scopus 로고    scopus 로고
    • IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis
    • Li,A., Dubey,S., Varney,M.L., Dave,B.J. and Singh,R.K. (2003) IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis. J. Immunol., 170, 3369-3376.
    • (2003) J. Immunol. , vol.170 , pp. 3369-3376
    • Li, A.1    Dubey, S.2    Varney, M.L.3    Dave, B.J.4    Singh, R.K.5
  • 33
    • 0030992837 scopus 로고    scopus 로고
    • Signalling through the lipid products of phosphoinositide-3-OH kinase
    • Toker,A. and Cantley,L.C. (1997) Signalling through the lipid products of phosphoinositide-3-OH kinase. Nature, 387, 673-676.
    • (1997) Nature , vol.387 , pp. 673-676
    • Toker, A.1    Cantley, L.C.2
  • 34
    • 0034652392 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells
    • Jiang,B.H., Zheng,J.Z., Aoki,M. and Vogt,P.K. (2000) Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells. Proc. Natl Acad. Sci. USA, 97, 1749-1753.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 1749-1753
    • Jiang, B.H.1    Zheng, J.Z.2    Aoki, M.3    Vogt, P.K.4
  • 35
    • 0033517190 scopus 로고    scopus 로고
    • NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling
    • Romashkova,J.A. and Makarov,S.S. (1999) NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling. Nature, 401, 86-90.
    • (1999) Nature , vol.401 , pp. 86-90
    • Romashkova, J.A.1    Makarov, S.S.2
  • 36
    • 14644410403 scopus 로고    scopus 로고
    • Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and downregulation of survivin, Akt and NF-kappaB: Implications for angioprevention and antiangiogenic therapy
    • Singh,R.P., Dhanalakshmi,S., Agarwal,C. and Agarwal,R. (2005) Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and downregulation of survivin, Akt and NF-kappaB: implications for angioprevention and antiangiogenic therapy. Oncogene, 24, 1188-1202.
    • (2005) Oncogene , vol.24 , pp. 1188-1202
    • Singh, R.P.1    Dhanalakshmi, S.2    Agarwal, C.3    Agarwal, R.4
  • 37
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-Kinase AKT pathway in human cancer
    • Vivanco,I. and Sawyers,C.L. (2002) The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat. Rev. Cancer, 2, 489-501.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 38
    • 0034745353 scopus 로고    scopus 로고
    • Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells
    • Zhou,B.P., Liao,Y., Xia,W., Spohn,B., Lee,M.H. and Hung,M.C. (2001) Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells. Nat. Cell Biol., 3, 245-252.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 245-252
    • Zhou, B.P.1    Liao, Y.2    Xia, W.3    Spohn, B.4    Lee, M.H.5    Hung, M.C.6
  • 39
    • 0035949588 scopus 로고    scopus 로고
    • A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus
    • Mayo,L.D. and Donner,D.B. (2001) A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus. Proc. Natl Acad. Sci. USA, 98, 11598-11603.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 11598-11603
    • Mayo, L.D.1    Donner, D.B.2
  • 40
    • 0038756445 scopus 로고    scopus 로고
    • PTEN and phosphatidylinositol 3′-kinase inhibitors up-regulate p53 and block tumor-induced angiogenesis: Evidence for an effect on the tumor and endothelial compartment
    • Su,J.D., Mayo,L.D., Donner,D.B. and Durden,D.L. (2003) PTEN and phosphatidylinositol 3′-kinase inhibitors up-regulate p53 and block tumor-induced angiogenesis: Evidence for an effect on the tumor and endothelial compartment. Cancer Res., 63, 3585-3592.
    • (2003) Cancer Res. , vol.63 , pp. 3585-3592
    • Su, J.D.1    Mayo, L.D.2    Donner, D.B.3    Durden, D.L.4
  • 41
    • 0035736487 scopus 로고    scopus 로고
    • HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation
    • Zhou,B.P., Liao,Y., Xia,W., Zou,Y., Spohn,B. and Hung,M.C. (2001) HER-2/ neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation. Nat. Cell Biol, 3, 973-982.
    • (2001) Nat. Cell Biol , vol.3 , pp. 973-982
    • Zhou, B.P.1    Liao, Y.2    Xia, W.3    Zou, Y.4    Spohn, B.5    Hung, M.C.6
  • 44
    • 0035028599 scopus 로고    scopus 로고
    • Kinetics of p53 binding to promoter sites in vivo
    • Szak,S.T., Mays,D. and Pietenpol,J.A. (2001) Kinetics of p53 binding to promoter sites in vivo. Mol. Cell. Biol., 21, 3375-3386.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3375-3386
    • Szak, S.T.1    Mays, D.2    Pietenpol, J.A.3
  • 45
    • 0034794571 scopus 로고    scopus 로고
    • The Survivin saga goes in vivo
    • Reed,J.C. (2001) The Survivin saga goes in vivo. J. Clin. Invest., 108, 965-969.
    • (2001) J. Clin. Invest. , vol.108 , pp. 965-969
    • Reed, J.C.1
  • 48
    • 12544259115 scopus 로고    scopus 로고
    • A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication
    • Xiang,R., Mizutani,N., Luo,Y., Chiodoni,C., Zhou,H., Mizutani,M., Ba,Y., Becker,J.C. and Reisfeld,R.A. (2005) A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication. Cancer Res., 65, 553-561.
    • (2005) Cancer Res. , vol.65 , pp. 553-561
    • Xiang, R.1    Mizutani, N.2    Luo, Y.3    Chiodoni, C.4    Zhou, H.5    Mizutani, M.6    Ba, Y.7    Becker, J.C.8    Reisfeld, R.A.9
  • 49
    • 18344369169 scopus 로고    scopus 로고
    • Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway
    • Mirza,A., McGuirk,M., Hockenberry,T.N. et al. (2002) Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway. Oncogene, 21, 2613-2622.
    • (2002) Oncogene , vol.21 , pp. 2613-2622
    • Mirza, A.1    McGuirk, M.2    Hockenberry, T.N.3
  • 50
    • 27844515642 scopus 로고    scopus 로고
    • Molecular mechanisms of action of angiopreventive anti-oxidants on endothelial cells: Microarray gene expression analyses
    • Pfeffer,U., Ferrari,N., Dell'eva,R., Indraccolo,S., Morini,M., Noonan,D.M. and Albini,A. (2005) Molecular mechanisms of action of angiopreventive anti-oxidants on endothelial cells: Microarray gene expression analyses. Mutat. Res., 591, 198-211.
    • (2005) Mutat. Res. , vol.591 , pp. 198-211
    • Pfeffer, U.1    Ferrari, N.2    Dell'eva, R.3    Indraccolo, S.4    Morini, M.5    Noonan, D.M.6    Albini, A.7
  • 51
    • 0033789022 scopus 로고    scopus 로고
    • Antiapoptotic and antigenotoxic effects of N-acetylcysteine in human cells of endothelial origin
    • Aluigi,M.G., De Flora,S., D'Agostini,F., Albini,A. and Fassina,G. (2000) Antiapoptotic and antigenotoxic effects of N-acetylcysteine in human cells of endothelial origin. Anticancer Res, 20, 3183-3187.
    • (2000) Anticancer Res , vol.20 , pp. 3183-3187
    • Aluigi, M.G.1    De Flora, S.2    D'Agostini, F.3    Albini, A.4    Fassina, G.5
  • 52
    • 3242664189 scopus 로고    scopus 로고
    • Mechanisms of inhibition of tumor angiogenesis and vascular tumor growth by epigallocatechin-3-gallate
    • Fassina,G., Vene,R., Morini,M., Minghelli,S., Benelli,R., Noonan,D.M. and Albini,A. (2004) Mechanisms of inhibition of tumor angiogenesis and vascular tumor growth by epigallocatechin-3-gallate. Clin. Cancer Res., 10, 4865-4873.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 4865-4873
    • Fassina, G.1    Vene, R.2    Morini, M.3    Minghelli, S.4    Benelli, R.5    Noonan, D.M.6    Albini, A.7
  • 53
    • 31544439674 scopus 로고    scopus 로고
    • Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival
    • Troussard,A.A., McDonald,P.C., Wederell,E.D. et al. (2006) Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival. Cancer Res., 66, 393-403.
    • (2006) Cancer Res. , vol.66 , pp. 393-403
    • Troussard, A.A.1    McDonald, P.C.2    Wederell, E.D.3
  • 54
    • 0033623902 scopus 로고    scopus 로고
    • Nuclear factor-kappaB activity correlates with growth, angiogenesis, and metastasis of human melanoma cells in nude mice
    • Huang,S., DeGuzman,A., Bucana,C.D. and Fidler,I.J. (2000) Nuclear factor-kappaB activity correlates with growth, angiogenesis, and metastasis of human melanoma cells in nude mice. Clin. Cancer Res., 6, 2573-2581.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 2573-2581
    • Huang, S.1    De Guzman, A.2    Bucana, C.D.3    Fidler, I.J.4
  • 55
    • 4544342570 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: The enemy within
    • Aggarwal,B.B. (2004) Nuclear factor-kappaB: The enemy within. Cancer Cell, 6, 203-208.
    • (2004) Cancer Cell , vol.6 , pp. 203-208
    • Aggarwal, B.B.1
  • 56
    • 28244456279 scopus 로고    scopus 로고
    • Tumor inflammatory angiogenesis and its chemoprevention
    • Albini,A., Tosetti,F., Benelli,R. and Noonan,D.M. (2005) Tumor inflammatory angiogenesis and its chemoprevention. Cancer Res., 65, 10637-10641.
    • (2005) Cancer Res. , vol.65 , pp. 10637-10641
    • Albini, A.1    Tosetti, F.2    Benelli, R.3    Noonan, D.M.4
  • 57
    • 20544460173 scopus 로고    scopus 로고
    • Rescuing COX-2 inhibitors from the waste bin
    • Albini,A. and Noonan,D.M. (2005) Rescuing COX-2 inhibitors from the waste bin. J. Natl. Cancer Inst., 97, 859-860.
    • (2005) J. Natl. Cancer Inst. , vol.97 , pp. 859-860
    • Albini, A.1    Noonan, D.M.2
  • 58
    • 0031009807 scopus 로고    scopus 로고
    • Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor alpha-dependent angiogenesis
    • Yoshida,S., Ono,M., Shono,T., Izumi,H., Ishibashi,T., Suzuki,H. and Kuwano,M. (1997) Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor alpha-dependent angiogenesis. Mol. Cell. Biol., 17, 4015-4023.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 4015-4023
    • Yoshida, S.1    Ono, M.2    Shono, T.3    Izumi, H.4    Ishibashi, T.5    Suzuki, H.6    Kuwano, M.7
  • 60
    • 0030777119 scopus 로고    scopus 로고
    • Expression of interleukin-8 by human melanoma cells up-regulates MMP-2 activity and increases tumor growth and metastasis
    • Luca,M., Huang,S., Gershenwald,J.E., Singh,R.K., Reich,R. and Bar-Eli,M. (1997) Expression of interleukin-8 by human melanoma cells up-regulates MMP-2 activity and increases tumor growth and metastasis. Am. J. Pathol., 151, 1105-1113.
    • (1997) Am. J. Pathol. , vol.151 , pp. 1105-1113
    • Luca, M.1    Huang, S.2    Gershenwald, J.E.3    Singh, R.K.4    Reich, R.5    Bar-Eli, M.6


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