Expression of interleukin-8 by human melanoma cells up-regulates MMP-2 activity and increases tumor growth and metastasis

American Journal of Pathology

Volumn 151, Issue 4, 1997, Pages 1105-1113

  Luca, Mario ^a   Huang, Suyun ^a   Gershenwald, Jeffrey E ^a   Singh, Rakesh K ^a   Reich, Reuven ^b   Bar Eli, Menashe ^a,c  

^a UNIVERSITY OF TEXAS   (United States)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; INTERLEUKIN 8;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MALE; MELANOMA; METASTASIS; METASTASIS POTENTIAL; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; CHLORAMPHENICOL O-ACETYLTRANSFERASE; GELATINASES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERLEUKIN-8; LUNG NEOPLASMS; MALE; MATRIX METALLOPROTEINASE 2; MELANOMA; METALLOENDOPEPTIDASES; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM TRANSPLANTATION; RNA, MESSENGER; SKIN NEOPLASMS; TRANSFECTION; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0030777119     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (59)

1. Fidler IJ: Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes Memorial Award Lecture. Cancer Res 1990, 50:6130-6138
2. Radinsky R: Growth factors and their receptors in metastasis. Semin Cancer Biol 1991, 2:169-177
3. Matte S, Colombo MP, Melani C, Silvani A, Parmiani G, Herlyn M: Expression of cytokine/growth factors and their receptors in human melanoma and melanocytes. Int J Cancer 1994, 56:853-857
4. Kerbel RS: Expression of multi-cytokine resistance and multi-growth factor independence in advanced stage metastatic cancer. Am J Pathol 1992, 141:519-524
5. Herlyn M: Human melanoma: development and progression. Cancer Metastasis Rev 1990, 9:101-112
6. Richmond A, Lawson DH, Nixon DW, Stedman NJ, Stevens S, Chawla RK: Extraction of a melanoma-growth stimulatory activity from culture medium conditioned by the Hs0294 human melanoma cell line. Cancer Res 1983, 43:2106-2112
7. DeLarco JE, Pigott DA, Lazarus JA: Ectopic peptides released by a human melanoma cell line that modulate the transformed phenotype. Proc Natl Acad Sci USA 1985, 82:5015-5019
8. Westermark B, Johnsson A, Paulsson Y, Betsholtz C, Heldin CH, Herlyn M, Rodeck U, Koprowski H: Human melanoma cell lines of primary and metastatic origin express the genes encoding the chains of platelet-derived growth factor and produce a PDGF-like growth factor. Proc Natl Acad Sci USA 1986, 83:7197-7200
9. Halaban R, Kwon BS, Ghosh S, Delli Bovi P, Baird A: bFGF as an autocrine growth factor for human melanoma. Oncogene Res 1988, 3:177-186
10. Kock A, Schwarz T, Urbanski A, Peng Z, Vetterlein M, Miksche M, Ansel C, Kung HF, Luger TA: Expression and release of interleukin-1 by different human melanoma cell lines. J Natl Cancer Inst 1989, 81:36-42
11. Bennicelli JL, Elias J, Kern J, Guerry D: Production of interleukin-1 activity by cultured human melanoma cells. Cancer Res 1989, 49: 930-935
12. Lu C, Vickers MF, Kerbel RS: Interleukin-6: a fibroblast-derived growth inhibitor of human melanoma cells from early but not advanced stages of tumor progression. Proc Natl Acad Sci USA 1992, 89:9215-9216
13. Chen QY, Daniel V, Maher DW, Hersey P: Production of IL-10 by melanoma cells: examination of its role in immunosuppression mediated by melanoma. Int J Cancer 1995, 56:755-760
14. Huang S, Xie K, Bucana CD, Ullrich SE, Bar-Eli M: Interleukin-10 suppresses tumor growth and metastasis of human melanoma cells: potential inhibition of angiogenesis. Clin Cancer Res 1996, 2:1969-1979
15. Armstrong CA, Tara DC, Hart CE, Kock A, Luger TA, Ansel JC: Heterogeneity of cytokine production by human malignant melanoma cells. Exp Dermatol 1992, 1:37-45
16. Matsushima K, Morishita K, Yoshimura T, Lavu S, Kobayashi Y, Lew W, Appella E, Kung HF, Leonard EJ, Oppenheim JJ: Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin-1 and tumor necrosis factor. J Exp Med 1988, 167:1883-1893
17. Anisowitch A, Zojchowski D, Stedman G, Sager R: Functional diversity of gro gene expression in human fibroblasts and mammary epithelial cells. Proc Natl Acad Sci USA 1988, 85:9645-9649
18. Koch AE, Polverini PJ, Kunkel SL, Harlow LA, DiPietro LA, Elmer VM, Strieter RM: Interleukin-8 as a macrophage-derived mediator of angiogenesis. Science 1992, 258:1798-1801
19. Strieter RM, Kunkel SL, Elner VM, Martonyi CL, Koch AE, Polverini PJ, Elner SG: Interleukin-8: a corneal factor that induces neovascularization. Am J Pathol 1992, 141:1279-1284
20. Wang JM, Taraboletti G, Matsushima K, Damme JV, Montovani A: Induction of hepatotactic migration of melanoma cells by neutrophil activating protein/IL-8. Biochem Biophys Res Commun 1990, 169: 165-170
21. Singh RK, Gutman M, Radinsky R, Bucana CD, Fidler IJ: Expression of interleukin-8 correlates with the metastatic potential of human melanoma cells in nude mice. Cancer Res 1994, 54:3242-3247
22. Singh RK, Gutman M, Reich R, Bar-Eli M: Ultraviolet B irradiation promotes tumorigenic and metastatic properties in primary cutaneous melanoma via induction of interleukin-8. Cancer Res 1995, 55: 3669-3674
23. Verschragen CE, Giovanella BC, Mendoza JT, Kozielsky AI, Stehlin JS Jr: Specific organ metastasis of human melanoma cells injected into the arterial circulation of nude mice. Anticancer Res 1991, 11: 529-536
24. Fort P, Marty L, Piechaczyh M, Sabrouty SE, Dani C, Jeanteur P, Blanchard JM: Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family. Nucleic Acids Res 1985, 13:1431-1442
25. Radinsky R, Fidler IJ, Price JE, Esumi N, Tsan R, Petty CM, Bucana CD, Bar-Eli M: Terminal differentiation and apoptosis in experimental lung metastasis of human osteogenic sarcoma cells by wild type p53. Oncogene 1994, 9:1877-1883
26. Huang S, Singh RK, Xie K, Gutman M, Berry KK, Bucana CD, Fidler IJ, Bar-Eli M: Expression of the JE/MCP-1 gene suppresses metastatic potential in murine colon carcinoma cells. Cancer Immunol Immunother 1994, 39:231-238
27. Ballin M, Gomez DE, Sinha CC, Thorgeirsson UP: ras oncogene mediated activation of a 92 kd metalloproteinase showing correlation with the malignant phenotype. Biochem Biophys Res Commun 1988, 154:832-838
28. Huhtala P, Chow LT, Tryggvason K: Structure of the human type IV collagenase gene. J Biol Chem 1990, 265:11077-11082
29. Hudson JM, Frade R, Bar-Eli M: Wild-type p53 regulates its own transcription in a cell-type specific manner. DNA Cell Biol 1995, 14:759-766
30. Gorman CM, Moffat LF, Howard BH: Recombination genomes which express chloramphenicol acetyl-transferase in mammalian cells. Mol Cell Biol 1982, 2:1044-1051
31. Luca M, Hunt B, Bucana CD, Johnson JP, Fidler IJ, Bar-Eli M: Direct correlation between MUC18 expression and metastatic potential of human melanoma cells. Melanoma Res 1993, 3:35-41
32. Luca M, Lenzi R, Jackson DL, Gutman M, Fidler IJ, Bar-Eli M: p53 mutations are infrequent and do not correlate with the metastatic potential of human melanoma cells. Int J Oncol 1993, 3:19-22
33. Ray JM, Stetler-Stevenson WG: Gelatinase A activity directly modulates melanoma cell adhesion and spreading. EMBO J 1995, 14:908-917
34. Sozzani S, Azwu DE, Ellenburg MD, Locati M, Rieppi M, Rojas A, Montovani A, McPhail LC: Activation of phospholipase D by interleukin-8 in human neutrophils. Blood 1994, 84:3895-3901
35. Reich R, Blumenthal M, Liscovitch M: Role of phospholipase D in laminin-induced production of gelatinase A (MMP-2) in metastatic degradation cells. Clin Exp Metastasis 1995, 13:134-140
36. Liotta LA, Tryggvason K, Garbisa S, Hart I, Foltz CM, Shafie S: Metastatic potential correlates with enzymatic degradation of basement membrane collagen. Nature 1980, 284:67-68
37. Reich R, Thompson EW, Iwamoto Y, Martin GR, Deason JR, Fuller GC, Miskin R: Effects of inhibitors of plasminogen activator, serine proteinases, and collagenases IV on the invasion of basement membranes by metastatic cells. Cancer Res 1988, 48:3307-3312
38. Thorgeirsson UP, Turpeenniemi-Hujanen T, Williams JE, Westin EH, Hellman CA, Talmadge JE, Liotta LA: NIH/3T3 cells transfected with human tumor DNA containing activated ras oncogene express the metastatic phenotype in nude mice. Mol Cell Biol 1985, 5:259-262
39. Schonbeck U, Brandt E, Peterson F, Flad HD, Loppnow H: IL-8 specifically binds to endothelial but not to smooth muscle cells. J Immunol 1995, 154:2375-2383
40. Schadendorf D, Moller A, Algermissen B, Worm M, Sticherling M, Czarentzki BM: Interleukin 8 (IL-8) produced by human melanoma cells in vitro is an essential autocrine growth factor. J Immunol 1993, 151:2667-2675
41. Schadendorf D, Fichtner I, Makki A, Alijagic S, Kupper M, Mrowietz U, Henz BM: Metastatic potential of human melanoma cells in nude mice: characterization of phenotype, cytokine secretion and tumor-associated antigens. Br J Cancer 1996, 74:194-199
42. Schelbenbogen C, Mohler T, Haefela J, Hunstein W, Kellholz U: Serum interleukin 8 (IL-8) is elevated in patients with metastatic melanoma and correlates with tumor load. Melanoma Res 1995, 5:179-181
43. Kupper TS, Ballard D, Chua AO, McGuire JS, Flood P, Horowitz MC, Langdon R, Lightfoot L, Gubler U: Human keratinocytes contain mRNA indistinguishable from monocyte interleukin 1 mRNA. J Exp Med 1986, 164:2095-2100
44. Oxholm A, Oxholm P, Staberg B, Bendtzen K: Immunohistological detection of interleukin 1-like molecules and tumor necrosis factor in human epidermis before and after UVB-irradiation in vivo. Br J Dermatol 1988, 118:369-376
45. Sticherling M, Hetzel F, Schroder JM, Christopher E: Time- and stimulus-dependent secretion of NAP-1/IL-8 by human fibroblasts and endothelial cells. J Invest Dermatol 1993, 101:573-576
46. Singh RK, Gutman M, Llansa N, Fidler IJ: Interferon-β prevents the upregulation of interleukin-8 expression in human melanona cells. J Interferon Cytokine Res 1996, 16:577-584
47. Folkman J, Klagsbrun M: Angiogenic factors. Science 1987, 235. 444-447
48. Lu C, Kerbel RS: Cytokines, growth factors and the loss of negative growth controls in the progression of human cutaneous malignant melanoma. Curr Opin Oncol 1994, 6:212-220
49. Ferrone S, Marincola FM: Loss of HLA class I antigens by melanoma cells: molecular mechanisms, functional significance and clinical relevance. Immunol Today 1995, 16:487-494
50. Lehmann JM, Riethmuller G, Johnson JP: MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobin superfamily. Proc Natl Acad Sci USA, 1989, 86:9891-9895
51. Shih IM, Elder DE, Speicher D, Johnson JP, Herlyn M: Isolation and functional characterization of the A32 melanoma-associated antigen. Cancer Res 1990, 2514-2520
52. McGregor BC, McGregor JL, Weiss LM, Wood GS, Chung-Hong H, Boukerche H, Warnke RA: Presence of cytoadhesines (II b-IIIa-like glycoproteins on human metastatic melanoma but on benign melanocytes. Am J Clin Pathol 1989, 92:495-499
53. 31 subunit with tumor progression. Cancer Res 1990, 50:6757-6764
54. Natali PG, Nicotra MR, Winkler AB, Cavaliere R, Bigotti A, Ullrich A: Progression of human cutaneous melanoma is associated with loss of expression of c-KIT proto-oncogene receptor. Int J Cancer 1992, 52:197-201
55. Lassam N, Bickford S: Loss of c-KIT expression in cultured melanoma cells. Oncogene 7:51-56
56. Zakut R, Perils R, Eiyahu S, Yarden Y, Givol D, Lyman SD, Halaban R: Kit ligand (mast cell growth factor) inhibits the growth of kit-expressing melanoma cells. Oncogene 1993, 8:2221-2229
57. Huang S, Luca M, Gutman M, McConkey DJ, Langley KE, Lyman SD, Bar-Eli M: Enforced c-KIT expression renders highly metastatic human melanoma cells susceptible to stem cell factor-induced apoptosis and inhibits their tumorigenic and metastatic potential. Oncogene 1996, 13:2339-2347
58. Armstrong CA, Murray N, Kennedy M, Koppula SV, Tara D, Ansel JC: Melanoma-derived interleukin-6 inhibits in vivo melanoma growth. J Invest Dermatol 1994, 102:278-284
59. INK4/MTS-1) gene in human melanoma cells: relevance to tumor growth and metastasis. Oncogene 1995, 11:1399-1402