Pathobiology of osteoarthritis: Pathomechanisms and potential therapeutic targets

Current Drug Targets

Volumn 8, Issue 2, 2007, Pages 271-282

  Roach, H I ^a   Aigner, Thomas ^b   Soder, S ^b   Haag, J ^b   Welkerling, H ^c  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Apoptosis; Cartilage; Chondrocytes; Osteoarthritis; Therapy

Indexed keywords

COLLAGEN TYPE 11; COLLAGEN TYPE 11A2; COLLAGEN TYPE 2; COLLAGEN TYPE 2A1; COLLAGEN TYPE 3; COLLAGEN TYPE 9; COLLAGEN TYPE 9A1; COLLAGENASE 3; ESTROGEN RECEPTOR ALPHA; GELATINASE A; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 8; OSTEONECTIN; SCLEROPROTEIN; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN BINDING PROTEIN 7; SOMATOMEDIN C; STROMELYSIN; TENASCIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

ARTICULAR CARTILAGE; CARTILAGE CELL; CARTILAGE DEGENERATION; CARTILAGE MATRIX; CELL DEATH; CELL DEGENERATION; DISEASE COURSE; DRUG TARGETING; FUNCTIONAL GENOMICS; GENETIC SCREENING; HUMAN; JOINT DEGENERATION; JOINT DESTRUCTION; JOINT STIFFNESS; MECHANICAL STRESS; MOLECULAR GENETICS; OSTEOARTHRITIS; PATHOGENESIS; PHENOTYPE; REVIEW; SYMPTOMATOLOGY; SYNOVIUM; WESTERN HEMISPHERE;

ANTI-INFLAMMATORY AGENTS; CARTILAGE, ARTICULAR; DRUG DESIGN; EXTRACELLULAR MATRIX; HUMANS; OSTEOARTHRITIS;

EID: 33847242563     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/138945007779940160     Document Type: Review

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