Expression of membrane-type 1 matrix metalloproteinase and activation of progelatinase A in human osteoarthritic cartilage

American Journal of Pathology

Volumn 151, Issue 1, 1997, Pages 245-256

  Imai, Kazushi ^a,d   Ohta, Satoru ^a   Matsumoto, Tadami ^a   Fujimoto, Noboru ^a   Sato, Hiroshi ^b   Seiki, Motoharu ^a   Okada, Yasunori ^c  

^a Cancer Research Institute   (Japan)

^b School of Medicine   (Japan)

^c FUJI CHEMICAL INDUSTRIES LTD   (Japan)

^d KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME PRECURSOR; GELATINASE A; MATRIX METALLOPROTEINASE;

ARTICLE; CELL MIGRATION; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME IMMUNOASSAY; ENZYME SPECIFICITY; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AGED; AGED, 80 AND OVER; CARTILAGE, ARTICULAR; CELL MEMBRANE; CELLS, CULTURED; COLLAGENASES; ENZYME ACTIVATION; ENZYME PRECURSORS; GELATINASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTERLEUKIN-1; MATRIX METALLOPROTEINASE 1; METALLOENDOPEPTIDASES; MIDDLE AGED; OSTEOARTHRITIS; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030875073     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Felson DT: Epidemiology of hip and knee osteoarthritis. Epidemiol Rev 1988, 10:1-28
2. Houg AJ, Sokoloff L: Pathology of osteoarthritis. Arthritis and Allied Conditions. Edited by DJ McCarty. Philadelphia, Lea & Febiger, 1989, pp 1571-1594
3. Nagase H, Woessner JF Jr: Role of endogenous proteinases in the degradation of cartilage matrix. Joint Cartilage Degradation. Edited by JF Woessner Jr, DS Howell. New York, Marcel Dekker, 1993, pp 159-185
4. Nagase H, Okada Y: Proteinases and matrix degradation. Textbook of Rheumatology. Edited by WN Kelly, ED Harris Jr, S Ruddy, CB Sledge. Philadelphia, Saunders Co, 1997, pp 323-341
5. Fosang AJ, Neame PJ, Last K, Hardingham TE, Murphy G, Hamilton JA: The interglobular domain of cartilage aggrecan is cleaved by PUMP, gelatinases and cathepsin B. J Biol Chem 1992, 270:19470-19474
6. Nguyen Q, Murphy G, Hughes C, Mort JS, Roughley PJ: Matrix metalloproteinases cleave at two distinct sites on human cartilage link protein. Biochem J 1993, 295:595-598
7. Imai K, Hiramatsu A, Fukushima D, Pierschbacher MD, Okada Y: Degradation of decorin by matrix metalloproteinases: identification of the cleavage sites, kinetic analyses and transforming growth factor-/31 release. Biochem J 1997, 322:809-814
8. Okada Y, Morodomi T, Enghild JJ, Suzuki K, Yasui A, Nakanishi I, Salvesen G, Nagase H: Matrix metalloproteinase 2 from human rheumatoid synovial fibroblasts: purification and activation of the precursor and enzymic properties. Eur J Biochem 1990, 194:721-730
9. Welgus HG, Fliszar CJ, Seltzer JL, Schmid TM, Jeffrey JJ: Differential susceptibility of type X collagen to cleavage by two mammalian interstitial collagenases and 72-kDa type IV collagenase. J Biol Chem 1990, 265:13521-13527
10. Murphy G, Cawston TE, Galloway WA, Barnes MJ, Bunnig RAD, Mercer E, Reynolds JJ, Burgeson RE: Metalloproteinases from rabbit bone culture medium degrade types IV and V collagens, laminin and fibronectin. Biochem J 1981, 199:807-811
11. Mohtai M, Smith RL, Schurman DJ, Tsuji Y, Torti FT, Hutchinson NI, Stetler-Stevenson WG, Goldberg Gl: Expression of 92-kD type IV collagenase/gelatinase (gelatinase B) in osteoarthritic cartilage and its induction in normal human articular cartilage by interleukin 1. J Clin Invest 1993, 92:179-185
12. Ward RV, Atkinson SJ, Reynolds JJ, Murphy G: Cell surface activation of progelatinase A: demonstration of the involvement of the C-terminal domain of progelatinase A in cell surface binding and activation of progelatinase A by primary fibroblasts. Biochem J 1994, 304:263-269
13. Sato H, Takino T, Okada Y, Cao J, Shinagawa A, Yamamoto E, Seiki M: A matrix metalloproteinase ex-pressed on the surface of invasive tumour cells. Nature 1994, 370:61-65
14. Mankin HJ, Dorfman H, Lippiello L, Zarins A: Biochemical and metabolic abnormalities in human articular cartilage from osteoarthritic human hips. II. Correlation of morphology with biochemical and metabolic data. J Bone Joint Surg Am 1971, 53A:523-537
15. Ohuchi E, Imai K, Fujii Y, Sato H, Seiki M, .Okada Y: Membrane-type 1-matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules. J Biol Chem 1997, 272:2446-2451
16. Nomura H, Sato H, Seiki M, Mai M, Okada Y: Expression of membrane-type matrix metalloproteinase in human gastric carcinomas. Cancer Res 1995, 55:32633266
17. Fujimoto N, Mouri N, Iwata K, Ohuchi E, Okada Y, Hayakawa T: A one-step sandwich enzyme immunoassay for human matrix metalloproteinase 2 (72-kDa gelatinase/type IV collagenase) using monoclonal antibodies. Clin Chim Acta 1993, 221:91-103
18. Okada Y, Naka K, Kawamura K, Matsumoto T, Nakanishi I, Fujimoto N, Sato H, Seiki M: Localization of matrix metalloproteinase 9 (92-kilodalton gelatinase/type IV collagenase = gelatinase B) in osteoclasts: implications for bone résorption. Lab Invest 1995, 72:311-322
19. Davies B, Miles DW, Happerfield LC, Naylor MS, Bobrow LG, Rubens RD, Balkwill FR: Activity of type IV collagenase in benign and malignant breast disease. Br J Cancer 1993, 67:1126-1131
20. Aydelotte MB, Kuettner KE: Differences between subpopulations of cultured bovine articular chondrocytes. I. Morphology and cartilage matrix production. Connect Tissue Res 1988, 18:205-222
21. Chomczynski P, Sacchi N: Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987, 162:156-159
22. Sato H, Kida Y, Mai M, Endo Y, Sasaki T, Tanaka J, Seiki M: Expression of genes encoding type IV collagen-degrading metalloproteinase and tissue inhibitors of metalloproteinases in various human tumor cells. Oncogene 1992, 7:77-83
23. Imai K, Ohuchi E, Aoki T, Nomura H, Fujii Y, Sato H, Seiki M, Okada Y: Membrane-type matrix metalloproteinase 1 is a gelatinolytic enzyme and secreted in a complex with tissue inhibitor of metalloproteinases 2. Cancer Res 1996, 56:2707-2710
24. Okada Y, Tsuchiya H, Shimizu H, Tomita K, Nakanishi I, Sato H, Seiki M, Yamashita K, Hayakawa T: Induction and stimulation of 92-kDa gelatinase/type IV collagenase production in osteosarcoma and fibrosarcoma cell lines by tumor necrosis factor a. Biochem Biophys Res Commun 1990, 171:610-617
25. Cole AA, Chubinskaya S, Schumacher B, Huch BK, Cs-Szabo G, Yao J, Mikecz K, Hasty KA, Kuettner KE: Chondrocyte matrix metalloproteinase-8: human articular chondrocytes express neutrophil collagenase. J Biol Chem 1996, 271:11023-11026
26. Mitchell PG, Magna HA, Reeves LM, Lopresti-Morow LL, Yocum SA, Rosner PJ, Geoghegan KF, Hambor JE: Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage. J Clin Invest 1996, 97:761-768
27. Reboul P, Pelletier JP, Tardif G, Cloutier JM, MartelPelletier J: The new collagenase, coIlagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes. J Clin Invest 1996, 97:2011-2019
28. Atkinson SJ, Crabbe T, Cowell S, Ward RV, Butler MJ, Sato H, Seiki M, Reynolds JJ, Murphy G: Intermolecular autolytic cleavage can contribute to the activation of progelatinase A by cell membrane. J Biol Chem 1995, 270:30479-30485
29. Sato H, Takino T, Kinoshita T, Imai K, Okada Y, StetlerStevenson WG, Seiki M: Cell surface binding and activation of gelatinase A induced by expression of membrane-type-1-matrix metalloproteinase (MT1-MMP). FEBS Lett 1996, 385:238-240
30. Kinoshita T, Sato H, Takino T, Itoh M, Akizawa T, Seiki M: Processing and a precursor of 72-kilodalton type IV collagenase/gelatinase A by a recombinant membrane-type 1 matrix metalloproteinase. Cancer Res 1996, 56:2535-2538
31. Pei D, Weiss SJ: Transmembrane-deletion mutants of the membrane-type matrix metalloproteinase-1 process progelatinase A and express intrinsic matrix-degrading activity. J Biol Chem 1996, 271:9135-9140
32. Tokuraku M, Sato H, Murakami S, Okada Y, Watanabe Y, Seiki M: Activation of the precursor of gelatinase A/72 kDa collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis. Int J Cancer 1995, 64:355-359
33. Häuselman HJ, Fernandes J, Mok SS, Schmid TM, Block JA, Aydelotte MB, Kuettner KE, Thonar EJA: Phenotypic stability of bovine articular chondrocytes after long-term culture in alginate beads. J Cell Sei 1994, 107:17-27
34. Hollander AP, Heathfield TF, Webber C, Iwata Y, Bourne R, Rorabeck C, Poole AR: Increased damage to type II collagen in osteoarthritic articular cartilage detected by a new immunoassay. J Clin Invest 1994, 93:1722-1732
35. Hollander AP, Pidoux l, Reiner A, Roranbeck C, Bourne R, Poole AR: Damage of type II collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration. J Clin Invest 1995, 96: 2859-2869
36. Okada Y, Shinmei M, Tanaka O, Naka K, Kimura A, Nakanishi I, Bayliss MT, Iwata K, Nagase H: Localization of matrix metalloproteinase 3 (stromelysin) in osteoarthritic cartilage and synovium. Lab Invest 1992, 66:680-690
37. Chubinskaya S, Huch K, Mikecz K, Cs-Szabo G, Hasty KA, Kuettner KE, Cole AA: Chondrocyte matrix metalloproteinase-8: up-regulation of neutrophil colla-genäse by interleukin-1β in human cartilage from knee and ankle joints. Lab Invest 1996, 74:232-240
38. Lewalle JM, Munaut C, Pichot B, Cataldo D, Baramova E, Foidart JM: Plasma membrane-dependent activation of gelatinase A in human vascular endothelial cells. J Cell Physiol 1995, 165:475-483
39. Lohi J, Keski-Oja J: Calcium ionophores decrease pericellular gelatinolytic activity via inhibition of 92-kDa gelatinase expression and decrease'of 72-kDa gelatinase activation. J Biol Chem 1995, 270:17602-17609
40. Lohi J, Lehti K, Westermarck J, Kähäri VM, Keski-Oja J: Regulation of membrane-type matrix metalloproteinase-1 expression by growth factors and phorbol 12myristate 13-acetate. Eur J Biochem 1996, 239:239247
41. Okada A, Bellocq JP, Rouyer N, Chenard MP, Rio MC, Chambon P, Basset P: Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas. Proc Natl Acad Sei USA 1995, 92:2730-2743
42. Westacott CI, Sharif M: Cytokines in osteoarthritis: mediators or markers of joint destruction. Semin Arthritis Rheum 1996, 25:254-272
43. Dodge GR, Poole AR: Immunohistochemical detection and immunohistochemical analysis of type II collagen degradation in human normal, rheumatoid, and osteoarthritic articular cartilages and in expiants of bovine articular cartilage cultured with interleukin 1. J Clin Invest 1989, 83:647-661
44. Mort JS, Dodge GR, Roughley PJ, Liu J, Dipasquale G, Poole AR: Direct évidence for active metalloproteinases mediating matrix degradation in interleukin 1-stimulated human articular cartilage. Matrix 1993, 13:95-102
45. Lark MW, Gordy JT, Weidner JR, Ayala J, Kimura JH, Williams HR, Mumford RA, Flannery CR, Carlson SS, Iwata-M, Sandy JD: Cell-mediated catabolism of aggrecan: evidence that cleavage at the "aggrecanase" site (Glu373-Ala374) is a primary event in proteolysis of the interglobular domain. J Biol Chem 1995, 270:2550-2556
46. Knäuper V, Will H, L6pez-0tïn C, Smith B, Atkinson SJ, Stanton H, Hembry RA, Murphy G: Cellular mechanism for human procollagenase-3 (MMP-13) activation. J Biol Chem 1996, 271:17124-17131
47. Sandy JD, Plaas AHK, Koob TJ: Pathways of aggrecan processing in joint tissues: implications for disease mechanism and monitoring. Acta Orthop Scand 1996, 66:26-32
48. Sandy JD, Neam PJ, Boynton RE, Flannery CR: Catabolism of aggrecan in cartilage expiants: identification of a major cleavage site within the interglobular domain. J Biol Chem 1991, 266:8683-8685
49. Buttle DJ, Handley CJ, Llic MZ, Saklatvala J, Murata M, Barret AH: Inhibition of cartilage proteoglycan release by a specific inactivator of cathepsin B and an inhibitor of matrix metalloproteinases. Arthritis Rheum 1993, 36: 1709-1717