Articular chondrocytes produce factors that inhibit maturation of sternal chondrocytes in serum-free agarose cultures: A TGF-β independent process

Journal of Bone and Mineral Research

Volumn 12, Issue 9, 1997, Pages 1368-1377

  D'Angelo, Marina ^a   Pacifici, Maurizio ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGAROSE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; ARTICULAR CARTILAGE; BONE CELL; CARTILAGE CELL; CELL HYPERPLASIA; CELL MATURATION; CHICK EMBRYO; CONTROLLED STUDY; CULTURE MEDIUM; EMBRYO; EMBRYO DEVELOPMENT; NONHUMAN; POSTNATAL DEVELOPMENT; STERNUM;

ANIMALS; CARTILAGE, ARTICULAR; CELL DIFFERENTIATION; CELLS, CULTURED; CHICK EMBRYO; CULTURE MEDIA, SERUM-FREE; INSULIN-LIKE GROWTH FACTOR I; PHENOTYPE; SEPHAROSE; STERNUM; TRANSFORMING GROWTH FACTOR BETA;

EID: 0030774452     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.1997.12.9.1368     Document Type: Article

References (46)

1. Pacifici M 1995 Tenascin-C and the development of articular cartilage. Matrix Biol 14:689-698.
2. Stocum DL, Davis RM, Leger M, Conrad HE 1979 Development of the tibiotarsus in the chick embryo: Biosynthetic activities of histologically distinct regions. J Embryol Exp Morphol 54:155-170.
3. Hunziker EB 1994 Mechanism of logitudinal bone growth and its regulation by growth plate chondrocytes. Micro Res Tech 28:505-519.
4. Cancedda R, Cancedda FD, Castagnola P 1995 Chondrocyte differentiation. Int Rev Cytol 159:265-358.
5. Tschan T, Hoerler I, Houze Y, Winterhalter KH, Richter C, Bruckner P 1990 Resting chondrocytes in culture survive without growth factors, but are sensitive to toxic oxygen metabolites. J Cell Biol 111:257-260.
6. Tschan T, Bohme K, Conscience-Egli M, Zenke G, Winterhalter kh, Bruckner P 1993 Autocrine or paracrine transforming growth factor-β modulates the phenotype of chick embryo sternal chondrocytes in serum-free agarose culture. J Biol Chem 268:5156-5161.
7. Kato Y, Iwamoto M 1990 Fibroblast growth factor is an inhibitor of chondrocyte terminal differentiation. J Biol Chem 265:5903-5909.
8. Ishizaki Y, Burne JF, Raff MC 1994 Autocrine signals enable chondrocytes to survive in culture. J Cell Biol 126:1069-1077.
9. Ballock RT, Reddi AH 1994 Thyroxine is the serum factor that regulates morphogenesis of columnar cartilage from isolated chondrocytes in chemically defined medium. J Cell Biol 126:1311-1318.
10. Bohme K, Winterhalter KH, Bruckner P 1995 Terminal differentiation of chondrocytes in culture is a spontaneous process and is arrested by transforming growth factor-β2 and basic fibroblast growth factor in synergy. Exp Cell Res 216:191-198.
11. Iwamoto M, Shimazu A, Pacifici M 1995 Regulation of chondrocyte maturation by fibroblast growth factor-2 and parathyroid hormone. J Orth Res 13:838-845.
12. Gibson GJ, Beaumont BW, Flint MH 1984 Synthesis of a low molecular weight collagen by chondrocytes from the presumptive calcification region of the embryonic chick sterna: The influence of culture in collagen gels. J Cell Biol 99:208-216.
13. Iwamoto M, Golden EB, Adams SL, Noji S, Pacifici M 1993 Responsiveness to retinoic acid changes during chondrocyte maturation. Exp Cell Res 205:213-224.
14. Bohme K, Conscience-Egli M, Tschan T, Winterhalter KH, Bruckner P 1992 Induction of proliferation or hypertrophy of chondrocytes in serum-free culture: The role of insulin-like growth factor-1, insulin, or thyroxine. J Cell Biol 116:1035-1042.
15. Pacifici M, Iwamoto M, Golden EB, Leatherman JL, Lee Y-S, Chuong C-M 1993 Tenascin is associated with articular cartilage development. Dev Dynam 198:123-134.
16. Pacifici M, Golden EB, Adams SL, Shapiro IM 1991 Cell hypertrophy and type X collagen synthesis in cultured articular chondrocytes. Exp Cell Res 192:266-270.
17. Benya PD, Shaffer JD 1982 Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels. Cell 30:215-224.
18. Yasui N, Nimni ME 1988 Cartilage collagens. In: Nimni ME (ed.) Collagen, Vol 1. CRC Press, Inc., FL, U.S.A., pp. 226-241.
19. Brewton RG, Wright DW, Mayne R 1991 Structural and functional comparison of Type IX collagen-prtoteoglycan from chicken cartilage and vitreous humor. J Biol Chem 266:4752-4757.
20. Schmid TM, Linsenmayer TF 1987 Type X collagen. In: Mayne R, Burgeson RE (eds.) Structure and function of collagen types. Academic Press, Inc., New York, NY, U.S.A., pp. 223-260.
21. Cole AA, Boyd T, Luchene L, Keuttner KE, Schmid TM 1993 Type X collagen degradation in long-term serum-free culture of the embryonic chick tibia following production of active collagenase and gelatinase. Dev Biol 159:528-534.
22. Eyre D, Wu J-J 1987 Type XI or 1α2α3α collagen. In: Mayne R, Burgeson RE (eds.) Structure and function of collagen types. Academic Press, Inc., New York, NY, U.S.A., pp. 261-282.
23. Abe M, Harpel JC, Metz CN, Nunes I, Loskutoff DJ, Rifkin DB 1994 An assay for transforming growth factor-β using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct. Anal Biochem 216:276-284.
24. Miyazono K, TenDijke P, Ichijo H, Heldin C-H 1994 Receptors for transforming growth factor-β. Adv Immunol 55:181-219.
25. Bruckner P, Horler I, Mendler M, Houze Y, Winterhalter KH, Eich-Bender S, Spycher MA 1989 Induction and prevention of chondrocyte hypertrophy in culture. J Cell Biol 109:2537-2545.
26. Romanoff AL 1960 The Avian Embryo. Macmillan Co., New York, NY, U.S.A.
27. Howlett CR 1979 The fine structure of the proximal growth plate of the avian tibia. J Anat 128:377-399.
28. Leboy PS, Shapiro IM, Uschmann BD, Oshima O, Lin D 1988 Gene expression in mineralizing chick epiphyseal cartilage. J Biol Chem 263:8515-8520.
29. Hammerman D 1989 The biology of osteoarthritis. N Engl J Med 320:1322-1330.
30. von der Mark K, Kirsch T, Nerlich A, Kuss A, Weseloh G, Gluckert K, Stoss H 1992 Type X collagen synthesis in human osteoarthritic cartilage. Arthritis Rheum 35:806-811.
31. Wroblewski J, Edwall-Arvidsson C 1995 Inhibitory effects of basic fibroclast growth factor on chondrocyte differentiation. J Bone Miner Res 10:735-742.
32. Deng C, Wynshaw-Boris A, Zhou F, Kuo A, Leder P 1996 Fibroblast growth factor receptor 3 is a negative regulator of bone growth. Cell 84:911-921.
33. Kato Y, Shimazu A, Nakashima K, Suzuki F, Jikko A, Iwamoto M 1990 Effects of parathyroid hormone and calcitonin on alkaline phosphatase activity and matrix calcification in rabbit growth plate chondrocyte cultures. Endocrinology 127:114-118.
34. Koike T, Iwamoto M, Shimazu A, Nakashima K, Suzuki F, Kato Y 1990 Potent mitogenic effects of parathyroid hormone (PTH) on embryonic chick and rabbit chondrocytes: Differential effects of age on growth, proteoglycan and cyclic AMP responses of chondrocytes to PTH. J Clin Invest 85:626-631.
35. Lanske B, Karaplis AC, Lee K, Luz A, Vortkamp A, Pirro A, Karperien M, Defize LHK, Ho C, Mulligan RC, Abou-Samra A-B, Juppner H, Segre GV, Kronenberg HM 1996 PTH/PTHrP receptor in early development and indian hedgehog-regulated bone growth. Science 273:663-666.
36. Gelb DE, Rosier RN, Puzas JE 1990 The production of transforming growth factor-β by chick growth plate chondrocytes in short term monolayer culture. Endocrinology 127:1941-1947.
37. Ballock RT, Heydemann A, Wakefield L, Flanders KC, Roberts AB, Sporn MB 1993 TGF-β1 prevents hypertrophy of epiphyseal chondrocytes: Regulation of gene expresssion for cartilage matrix proteins and metalloproteases. Dev Biol 158:414-429.
38. Thorp B, Anderson I, Jakowlew SB 1992 Transforming growth factor-β, -β2, -β3 in cartilage and bone cells during endochondral ossification in the chick. Development 114:907-911.
39. Lacombe-Gleize S, Gregoire M, Demignot S, Hoequel C, Adolphe M 1995 Implication of TGFβ1 in co-culture of chondrocytes-osteoblasts. In Vitro Cell Dev Biol 81:649-652.
40. Roberts AB, Sporn MB, Assoian RK, Smith JM, Roche NS, Wakefield LM, Heine UI, Liotta LA, Falanga V, Kehrl JH, Fauci AS 1986 Transforming growth factor type β: Rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc Natl Acad Sci USA 83:4167-4171.
41. Wahl SM, Hunt DA, Wakefield LM, McCartney-Francis N, Wahl LM, Roberts AB, Sporn MB 1987 Transforming growth factor type β induces monocyte chemotaxis and growth factor production. Proc Natl Acad Sci USA 84:5788-5792.
42. 3. J Biol Chem 269:28374-28381.
43. Morales TI, Roberts AB 1988 Transforming growth factor-β regulates the metabolism of proteoglycans in bovine cartilage organ cultures. J Biol Chem 263:12828-12831.
44. Fava R, Olson N, Keski-Oja J, Moses H, Pincus T 1989 Active and latent forms of TGFβ activity in synovial effusions. J Exp Med 169:291-296.
45. Iwamoto M, Yagami K, LuValle P, Olsen BR, Petropoulos CJ, Ewert DL, Pacifici M 1993 Expression and role of c-myc in chondrocytes undergoing endochondral ossification. J Biol Chem 268:9645-9652.
46. Iwamoto M, Shapiro IM, Yagami K, Boskey AL, Leboy PS, Adams SL, Pacifici M 1993 Retinoic acid induces rapid mineralization and expression of mineralization related genes in chondrocytes. Exp Cell Res 207:413-420.