Fatty acid modulation of endothelial activation

American Journal of Clinical Nutrition

Volumn 71, Issue 1 SUPPL., 2000, Pages

  De Caterina, Raffaele ^a   Liao, James K ^b   Libby, Peter ^b  

^a INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

^b NONE

Author keywords

Adhesion molecules; Atherogenesis; Endothelium; Inflammation; Leukocytes; Long chain fatty acids; Monocytes

Indexed keywords

DOCOSAHEXAENOIC ACID; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; INTERLEUKIN 8; MONOUNSATURATED FATTY ACID; POLYUNSATURATED FATTY ACID; SATURATED FATTY ACID; VASCULAR CELL ADHESION MOLECULE 1;

CELL ADHESION; CONFERENCE PAPER; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENDOTHELIUM; HUMAN; PROTEIN EXPRESSION;

BACTERIA (MICROORGANISMS);

EID: 0033956866     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/71.1.213s     Document Type: Conference Paper

References (101)

1. Ku DN, Giddens DP, Zarins CK, Glagov S. Pulsatile flow and atherosclerosis in the human carotid bifurcation: positive correlation between plaque location and low and oscillating shear stress. Arteriosclerosis 1985;5:293-302.
2. Stary H. Evolution and progression of atherosclerotic lesions in coronary arteries of children and young adults. Arteriosclerosis 1989;88(suppl):1-32.
3. Fuster V, Badimon L, Badimon JJ, Chesebro JH. The pathogenesis of coronary artery disease and the acute coronary syndromes (first of two parts). N Engl J Med 1992;326:242-51.
4. Gerrity RG. The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions. Am J Pathol 1981;103:181-90.
5. Joris I, Znad T, Nunnari JJ, Krolikowski FJ, Majno G. Adhesion and emigration of mononuclear cells in the aorta of hypercholesterolemic rats. Am J Pathol 1983;113:341-58.
6. Faggiotto A, Ross R, Harker L. Studies of hypercholesterolemia in the nonhuman primate. I. Changes that lead to fatty streak formation. Arteriosclerosis 1984;4:323-40.
7. Rosenfeld ME, Tsukada T, Gown AM, Ross R. Fatty streak initiation in Watanabe heritable hyperlipemic and comparably hypercholesterolemic fat-fed rabbits. Arteriosclerosis 1987;7:9-23.
8. Masuda J, Ross R. Atherogenesis during low level hypercholesterolemia in the nonhuman primate. I. Fatty streak formation. Arteriosclerosis 1990;10:164-77.
9. Faggiotto A, Ross R. Studies of hypercholesterolemia in the nonhuman primate. II. Fatty streak conversion to fibrous plaque. Arteriosclerosis 1984;4:341-56.
10. Masuda J, Ross R. Atherogenesis during low level hypercholesterolemia in the nonhuman primate. II. Fatty streak conversion to fibrous plaque. Arteriosclerosis 1990;10:178-87.
11. Mitchell JRA, Schwartz CJ. Arterial Disease. Oxford, UK: Blackwell Scientific Publishers, 1965.
12. Smith EB, Slater RS. Lipids and low-density lipoproteins in intima in relationship to its morphological characteristics. In: Schletter D, Weizel A, eds. Atherogenesis: initiating factors. Ciba Foundation symposium no. 12. Amsterdam: Elsevier Publishing Co, 1973:39-51.
13. Smith EB, Slater RS, Crothers DX. Quantitative interrelationships between plasma constituents and normal and atherosclerotic human intimal tissue. In: Schletter D, Weizel A, eds. Atherosclerosis III. Berlin: Springer-Verlag, 1974:96-102.
14. Gimbrone MA Jr. Endothelial dysfunction and the pathogenesis of atherosclerosis. In: Fidge N, Nestel P, eds. Atherosclerosis VII. New York: Elsevier Science Publishers, 1986:367-9.
15. Ross R. The pathogenesis of atherosclerosis: an update. N Engl J Med 1986;314:488-500.
16. Gimbrone MA Jr. Endothelial dysfunction and atherosclerosis. J Cardiac Surg 1989;4:180-3.
17. De Caterina R, Gimbrone MA Jr. Leukocyte-endothelial interactions and the pathogenesis of atherosclerosis. In: Kristensen SD, Schmidt EB, De Caterina R, Endres S, eds. n - 3 Fatty acids - prevention and treatment in vascular disease. London: Springer Verlag, 1995:9-24.
18. Ross R, Glomset J. The pathogenesis of atherosclerosis. Part I. N Engl J Med 1976;295:369-77.
19. Ross R, Glomset J. The pathogenesis of atherosclerosis. Part II. N Engl J Med 1976;295:420-5.
20. Libby P. Atheroma: more than mush. Lancet 1996;248(suppl):S4-7.
21. Gimbrone MA Jr, ed. Vascular endothelium in hemostasis and thrombosis. Edinburgh: Churchill Livingstone, 1986.
22. Gimbrone MA Jr, Bevilacqua MP. Vascular endothelium: functional modulation at the blood interface. In: Simionescu N, Simionescu M, eds. Endothelial cell biology in health and disease. New York: Plenum Press, 1988:255-73.
23. Gimbrone MA Jr, Kume N, Cybulsky MI. Vascular endothelial dysfunction and the pathogenesis of atherosclerosis. In: Weber P, Leaf A, eds. Atherosclerosis reviews. Vol 25. New York: Raven Press, 1993.
24. Cybulsky MI, Gimbrone MA Jr. Endothelial-leukocyte adhesion molecules in acute inflammation and atherogenesis. In: Simionescu N, Simionescu M, eds. Endothelial cell dysfunctions. New York: Plenum Press, 1992:129-40.
25. Mackay C. Migration pathways and immunologic memory among T lymphocytes. Semin Immunol 1992;4:51-8.
26. Lasky L. Selectins: interpreters of cell-specific carbohydrate information during inflammation. Science 1992;258:964-9.
27. Rosen S. Cell surface lectins in the immune system. Semin Immunol 1993;5:237-47.
28. Oppenheim JJ, Zachariae CO, Mukaida N, Matsushima K. Properties of the novel proinflammatory supergene "intercrine" cytokine family. Annu Rev Immunol 1991;9:617-48.
29. Miller M, Krangel M. Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines. CRC Crit Rev Immunol 1992;12:17-46.
30. Springer TA. Adhesion receptors of the immune system. Nature 1990;346:425-34.
31. Mulligan M, Varani J, Dame M, et al. Role of endothelial-leukocyte adhesion molecule 1 (ELAM-1) in neutrophil-mediated lung injury in rats. J Clin Invest 1991;88:1396-406.
32. Picker L, Butcher E. Physiological and molecular mechanisms of lymphocyte homing. Annu Rev Immunol 1992;10:561-91.
33. Mayadas T, Johnson R, Rayburn H, Hynes R, Wagner D. Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice. Cell 1993;74:541-54.
34. Landis R, Bennett R, Hogg N. A novel LFA-1 activation epitope maps to the I domain. J Cell Biol 1993;120:1519-27.
35. Diamond MS, Springer TA. A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen. J Cell Biol 1993;120:545-56.
36. Chan BMC, Elices MJ, Murphy E, Hemler ME. Adhesion to vascular cell adhesion molecule 1 and fibronectin: comparison of alpha 4 beta 1 (VLA-4) and alpha 4 beta 7 on the human B cell line JY. J Biol Chem 1992;267:8366-70.
37. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 1994;76:301-14.
38. Luscinskas FW, Gimbrone MA Jr. Endothelial-dependent mechanisms in chronic inflammatory leukocyte recruitment. Annu Rev Med 1996;47:413-21.
39. Cybulsky MI, Fries JWU, Williams AJ, et al. Alternative splicing of human VCAM-1 in activated vascular endothelium. Am J Pathol 1991;138:815-23.
40. Cybulsky MI, Fries JWU, Williams AJ, Sultan P, Gimbrone MA Jr, Collins T. Gene structure, chromosomal location, and basis for alternative mRNA splicing of the human VCAM-1 gene. Proc Natl Acad Sci U S A 1991;88:7859-63.
41. Bochner BS, Luscinskas FW, Gimbrone MA Jr, et al. Adhesion of human basophils, eosinophils, and neutrophils to interleukin-1-activated human vascular endothelial cells: contribution of endothelial cell adhesion molecules. J Exp Med 1991;173:1553-6.
42. Li H, Cybulsky MI, Gimbrone MA Jr, Libby P. An atherogenic diet rapidly induces VCAM-1, a cytokine-regulatable mononuclear leukocyte adhesion molecule, in rabbit aortic endothelium. Arterioscler Thromb 1993;13:197-204.
43. Erbe DV, Wolitzky BA, Presta LG, et al. Identification of an E-selectin region critical for carbohydrate recognition and cell adhesion. J Cell Biol 1992;119:215-27.
44. Spertini O, Luscinskas FW, Kansas GS, et al. Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion. J Immunol 1991; 147: 2565-73.
45. Rollins BJ. JE/MCP-1: an early response gene encodes a monocyte-specific cytokine. Cancer Cells 1991;3:517-24.
46. Clinton SK, Underwood R, Sherman ML, Kufe DK, Libby P. Macrophage-colony stimulating factor gene expression in vascular cells and in experimental and human atherosclerosis. Am J Pathol 1992;140:301-16.
47. Cybulsky MI, Gimbrone MA Jr. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science 1991;251:788-91.
48. Rosenfeld M, Ylä-Herttuala S, Lipton B, Ord V, Witztum J, Steinberg D. Macrophage colony-stimulating factor mRNA and protein in atherosclerotic lesions of rabbits and humans. Am J Pathol 1992; 140:291-300.
49. Poston R, Haskard D, Coucher J, Gall N, Johnson-Tiedy R. Expression of intercellular adhesion molecule-1 in atherosclerotic plaques. Am J Pathol 1992;140:665-73.
50. Nelken N, Coughlin S, Gordon D, Wilcox J. Monocyte chemoattractant protein-1 in human atheromatous plaques. J Clin Invest 1991;88:1121-7.
51. Kishimoto T, Taga T, Akira S. Cytokine signal transduction. Cell 1994;76:253-62.
52. Collins T. Endothelial nuclear factor-kappa B and the initiation of the atherosclerotic lesion. Lab Invest 1993;68:499-508.
53. Bauerle PA. The inducible transcription activator NF-kappa B: regulation by distinct protein subunits. Biochim Biophys Acta 1991; 1072:63-80.
54. Lenardo M, Baltimore D. NF-kappa B: a pleiotropic mediator of inducible and tissue specific gene control. Cell 1988;58:227-9.
55. Marui N, Offermann MK, Swerlick R, et al. Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. J Clin Invest 1993;92:1866-74.
56. Collins T, Read MA, Neish AS, Whitley MZ, Thanos D, Maniatis T. Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers. FASEB J 1995;9:899-909.
57. Clinton SK, Libby P. Cytokines and growth factors in atherogenesis. Arch Pathol Lab Med 1992;116:1292-300.
58. Schwenke D, Carew TE. Initiation of atherosclerotic lesions in cholesterol-fed rabbits. II. Selective retention of LDL vs. selective increases in LDL permeability in susceptible sites of arteries. Arteriosclerosis 1989;9:908-18.
59. Witztum J. The role of monocytes and oxidized LDL in atherosclerosis. In: Leaf A, Weber P, ed. Atherosclerosis reviews: prevention and noninvasive therapy of atherosclerosis. Vol 21. New York: Raven Press, 1990:59-69.
60. Witztum JL, Steinberg D. Role of oxidized low-density lipoprotein in atherogenesis. J Clin Invest 1991;88:1785-92.
61. Witztum JL. The oxidation hypothesis of atherosclerosis. Lancet 1994;344:793-5.
62. Parthasarathy S. Mechanism(s) of cell mediated oxidation of low density lipoprotein. In: Nohl H, Esterbauer H, Evans CR, eds. Free radicals in the environment, medicine and toxicology. London: Richelieu Press, 1994:163-79.
63. Territo M, Berliner J, Almada L, Ramirez R, Fogelman A. Beta-VLDL pretreatment of endothelial monolayers increases monocyte but not neutrophil adhesion. Arteriosclerosis 1989;9:824-8.
64. Cushing SD, Berliner JA, Valente AJ, et al. Minimally modified LDL induces monocyte chemotactic protein 1 in human endothelial and smooth muscle cells. Proc Natl Acad Sci U S A 1990;87:5134-8.
65. Rajavashisth TB, Andalibi A, Territo MC, et al. Induction of endothelial expression of granulocyte and macrophage colony-stimulating factors by modified low density lipoproteins. Nature 1990;344:254-7.
66. Kume N, Cybulsky M, Gimbrone MA Jr. Lysophosphatidyl-choline, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured endothelial cells. J Clin Invest 1992;90:1138-44.
67. Hessler JR, Robertson AJ, Chisolm GM. LDL-induced cytotoxicity and its inhibition by HDL in human vascular smooth muscle and endothelial cells in culture. Atherosclerosis 1979;32:213-29.
68. Parthasarathy S, Barnett J, Fong LG. High density lipoprotein inhibits the oxidative modification of low-density lipoprotein. Biochim Biophys Acta 1990;1044:275-83.
69. Stafforini DM, Zimmerman GA, McIntyre TM, Prescott SM. The platelet activating factor acetylhydrolase from human plasma prevents oxidative modification of low density lipoprotein. Trans Am Assoc Physicians 1993;106:44-63.
70. Resnick N, Collins T, Atkinson WJ, Bonthron DT, Dewey CFJ, Gimbrone MA Jr. Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element. Proc Natl Acad Sci U S A 1993;90:4591-5.
71. Nagel T, Resnick N, Atkinson WJ, Dewey CFJ, Gimbrone MA Jr. Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells. J Clin Invest 1994;94:885-91.
72. De Caterina R, Libby P, Peng H-B, et al. Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J Clin Invest 1995;96:60-8.
73. Shin W, Hong Y, Peng H, De Caterina R, Libby P, Liao JK. Nitric oxide attenuates vascular smooth muscle cell activation by interferon-γ. The role of constitutive NF-κB activity. J Biol Chem 1996;271:11317-24.
74. Peng H-B, Libby P, Liao JK. Induction and stabilization of I kappa B alpha by nitric oxide mediates inhibition of NF-kappa B. J Biol Chem 1995;270:14214-9.
75. Kromann N, Green A. Epidemiological studies in the Upernavik district, Greenland. Acta Med Stand 1980;208:401-6.
76. Bang HO, Dyerberg J, Hjorne N. The composition of food consumed by Greenland Eskimos. Acta Med Scand 1976;200:69-73.
77. Kagawa Y, Nishizawa M, Suzuki M. Eicosapolyenoic acid of serum lipids of Japanese islanders with low incidence of cardiovascular diseases. J Nutr Sci Vitaminol (Tokyo) 1982;28:441-53.
78. Hirai A, Hamazaki T, Terano T. Eicosapentaenoic acid and platelet function in Japanese. Lancet 1980;2:1132-3.
79. Arthaud B. Cause of death in 339 Alaskan natives as determined by autopsy. Arch Pathol 1970;90:433-8.
80. Middaugh JP. Cardiovascular deaths among Alaskan natives 1980-1986. Am J Public Health 1990;80:282-5.
81. Kromhout D, Bosschieter EB, De Lezenne Coulander C. The inverse relation between fish consumption and 20-year mortality from coronary heart disease. N Engl J Med 1985;312:1205-9.
82. Shekelle R, Missel L, Paul O, MacMillan-Schryock A, Stamler J. Fish consumption and mortality from coronary heart disease. N Engl J Med 1985;313:820 (letter).
83. Soei L, Lamers J, Sassen L, et al. Fish oil: a modulator of experimental atherosclerosis in animals. In: Kristensen S, Endres S, De Caterina R, Schmidt E, eds. n - 3 Fatty acids: prevention and treatment in vascular disease. London: Springer, 1995:77-84.
84. Newman WP, Middaugh JP, Propst MT, Rogers DR. Atherosclerosis in Alaska natives and non-natives. Lancet 1993;341:1056-7.
85. Eritsland J, Arnesen H, Grønseth K, Field NB, Abdelnoor M. Effect of supplementation with n - 3 fatty acids on graft patency in patients undergoing coronary artery bypass operation. Results from the SHOT study. Eur Heart J 1994;15:29 (abstr).
86. De Caterina R, Cybulsky MI, Clinton SK, Gimbrone MA Jr, Libby P. The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of pro-atherogenic and pro-inflammatory proteins in human endothelial cells. Arterioscler Thromb 1994;14: 1829-36.
87. De Caterina R, Cybulsky MA, Clinton SK, Gimbrone MA Jr, Libby P. Omega-3 fatty acids and endothelial leukocyte adhesion molecules. Prostaglandins Leukot Essent Fatty Acids 1995;52:191-5.
88. Baker RR, Chang H-Y. The hydrolysis of natural phosphatidylethanolamines by phospholipase A2 from rat serum: a degree of selectivity is shown for docosahexaenoate release. Biochim Biophys Acta 1992;1125:56-61.
89. Van Snick J. Interleukin-6: an overview. Annu Rev Immunol 1990; 8:253-78.
90. Weber C, Erl W, Pietsch A, Danesch U, Weber P. Docosahexaenoic acid selectively attenuates induction of vascular cell adhesion molecule-1 and subsequent monocytic cell adhesion to human endothelial cells stimulated by tumor necrosis factor-alpha. Arterioscler Thromb Vasc Biol 1995;15:622-8.
91. De Caterina R, Bernini W, Carluccio MA, Liao JK, Libby P. Structural requirements for inhibition of cytokine-induced endothelial activation by unsaturated fatty acids. J Lipid Res 1998;39: 1062-70.
92. Carluccio MA, Massaro M, Bonfrate C, et al. Oleic acid inhibits endothelial activation: a direct vascular antiatherogenic mechanism of a nutritional component in the Mediterranean diet. Arterioscler Thromb Vasc Biol 1999;19:220-8.
93. Meskini N, Nemoz G, Chapuy P, et al. Glutathione peroxidase activity and metabolism of arachidonic acid in peripheral blood mononuclear cells from elderly subjects. Clin Sci 1993;85:203-11.
94. Endres S, Ghorbani R, Kelley VE, et al. The effect of dietary supplementation with n - 3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells. N Engl J Med 1989;320:265-71.
95. Hansen JB, Olsen JO, Wilsgard L, Østerud B. Effects of dietary supplementation with cod liver oil on monocyte thromboplastin synthesis, coagulation and fibrinolysis. J Intern Med Suppl 1989; 225:133-9.
96. Kaminski WE, Jendraschak E, Kiefl R, von Schacky C. Dietary omega-3 fatty acids lower levels of platelet-derived growth factor mRNA in human mononuclear cells. Blood 1993;81:1871-9.
97. Lehr A-H, Hübner C, Finckh B, et al. Dietary fish oil reduces leukocyte/endothelium interaction following systemic administration of oxidatively modified low density lipoproteins. Circulation 1991; 84:1725-31.
98. Maier JA, Hla T, Maciag T. Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells. J Biol Chem 1990;265:10805-8.
99. Habib A, Creminon C, Frobert Y, Grassi J, Pradelles P, Maclouf J. Demonstration of an inducible cyclooxygenase in human endothelial cells using antibodies raised against the carboxyl-terminal region of the cyclooxygenase-2. J Biol Chem 1993;268: 23448-54.
100. Hla T, Neilson K. Human cyclooxygenase-2 cDNA. Proc Natl Acad Sci U S A 1992;89:7384-8.
101. De Caterina R, Bernini W, Carluccio MA, Liao JK, Libby P. Structural requirements for inhibition of cytokine-induced endothelial activation by unsaturated fatty acids. J Lipid Res 1998;39:1062-70.