Obligatory Role of NR2A for Metaplasticity in Visual Cortex

Neuron

Volumn 53, Issue 4, 2007, Pages 495-502

  Philpot, Benjamin D ^a   Cho, Kathleen K A ^b   Bear, Mark F ^b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

MOLNEURO; SYSNEURO

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; PROTEIN SUBUNIT;

ANIMAL CELL; ARTICLE; EXCITATORY POSTSYNAPTIC POTENTIAL; LONG TERM DEPRESSION; LONG TERM POTENTIATION; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; VISUAL CORTEX;

ACTION POTENTIALS; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; BRAIN CHEMISTRY; DARK ADAPTATION; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRIC STIMULATION; GENE EXPRESSION REGULATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONAL PLASTICITY; NEURONS; PATCH-CLAMP TECHNIQUES; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPTOSOMES; VISUAL CORTEX;

EID: 33846840971     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2007.01.027     Document Type: Article

References (60)

1. Abraham W.C., and Bear M.F. Metaplasticity: the plasticity of synaptic plasticity. Trends Neurosci. 19 (1996) 126-130
2. Barria A., and Malinow R. NMDA receptor subunit composition controls synaptic plasticity by regulating binding to CaMKII. Neuron 48 (2005) 289-301
3. Barth A.L., and Malenka R.C. NMDAR EPSC kinetics do not regulate the critical period for LTP at thalamocortical synapses. Nat. Neurosci. 4 (2001) 235-236
4. Bear M.F. Bidirectional synaptic plasticity: from theory to reality. Philos. Trans. R. Soc. Lond. B Biol. Sci. 358 (2003) 649-655
5. Berberich S., Punnakkal P., Jensen V., Pawlak V., Seeburg P.H., Hvalby O., and Kohr G. Lack of NMDA receptor subtype selectivity for hippocampal long-term potentiation. J. Neurosci. 25 (2005) 6907-6910
6. Bienenstock E.L., Cooper L.N., and Munro P.W. Theory for the development of neuron selectivity: orientation specificity and binocular interaction in visual cortex. J. Neurosci. 2 (1982) 32-48
7. Carmignoto G., and Vicini S. Activity-dependent decrease in NMDA receptor responses during development of the visual cortex. Science 258 (1992) 1007-1011
8. Chen W.S., and Bear M.F. Activity-dependent regulation of NR2B translation contributes to metaplasticity in mouse visual cortex. Neuropharmacology 52 (2007) 200-214 10.1016/j.neuropharm.2006.07.003 Published online August 8, 2006
9. Crair M.C., and Malenka R.C. A critical period for long-term potentiation at thalamocortical synapses. Nature 375 (1995) 325-328
10. Czepita D., Reid S.N., and Daw N.W. Effect of longer periods of dark rearing on NMDA receptors in cat visual cortex. J. Neurophysiol. 72 (1994) 1220-1226
11. Fagiolini M., Katagiri H., Miyamoto H., Mori H., Grant S.G., Mishina M., and Hensch T.K. Separable features of visual cortical plasticity revealed by N-methyl-D-aspartate receptor 2A signaling. Proc. Natl. Acad. Sci. USA 100 (2003) 2854-2859
12. Flint A.C., Maisch U.S., Weishaupt J.H., Kriegstein A.R., and Monyer H. NR2A subunit expression shortens NMDA receptor synaptic currents in developing neocortex. J. Neurosci. 17 (1997) 2469-2476
13. Fonseca R., Nagerl U.V., Morris R.G., and Bonhoeffer T. Competing for memory: hippocampal LTP under regimes of reduced protein synthesis. Neuron 44 (2004) 1011-1020
14. Fox K., Daw N., Sato H., and Czepita D. The effect of visual experience on development of NMDA receptor synaptic transmission in kitten visual cortex. J. Neurosci. 12 (1992) 2672-2684
15. Fu Z., Logan S.M., and Vicini S. Deletion of the NR2A subunit prevents developmental changes of NMDA-mEPSCs in cultured mouse cerebellar granule neurones. J. Physiol. 563 (2005) 867-881
16. 2+/calmodulin-dependent protein kinase II and postsynaptic density 95 for binding to the NR2A subunit of the NMDA receptor. J. Neurosci. 21 (2001) 1501-1509
17. Hestrin S. Developmental regulation of NMDA receptor-mediated synaptic currents at a central synapse. Nature 357 (1992) 686-689
18. Hollingsworth E.B., McNeal E.T., Burton J.L., Williams R.J., Daly J.W., and Creveling C.R. Biochemical characterization of a filtered synaptoneurosome preparation from guinea pig cerebral cortex: cyclic adenosine 3′:5′-monophosphate-generating systems, receptors, and enzymes. J. Neurosci. 5 (1985) 2240-2253
19. Husi H., Ward M.A., Choudhary J.S., Blackstock W.P., and Grant S.G. Proteomic analysis of NMDA receptor-adhesion protein signaling complexes. Nat. Neurosci. 3 (2000) 661-669
20. Kadotani H., Hirano T., Masugi M., Nakamura K., Nakao K., Katsuki M., and Nakanishi S. Motor discoordination results from combined gene disruption of the NMDA receptor NR2A and NR2C subunits, but not from single disruption of the NR2A or NR2C subunit. J. Neurosci. 16 (1996) 7859-7867
21. Kirkwood A., Rioult M.G., and Bear M.F. Experience-dependent modification of synaptic plasticity in visual cortex. Nature 381 (1996) 526-528
22. Kirson E.D., and Yaari Y. Synaptic NMDA receptors in developing mouse hippocampal neurones: functional properties and sensitivity to ifenprodil. J. Physiol. 497 (1996) 437-455
23. Krupp J.J., Vissel B., Thomas C.G., Heinemann S.F., and Westbrook G.L. Calcineurin acts via the C-terminus of NR2A to modulate desensitization of NMDA receptors. Neuropharmacology 42 (2002) 593-602
24. Kutsuwada T., Sakimura K., Manabe T., Takayama C., Katakura N., Kushiya E., Natsume R., Watanabe M., Inoue Y., Yagi T., et al. Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice. Neuron 16 (1996) 333-344
25. Laurie D.J., and Seeburg P.H. Ligand affinities at recombinant N-methyl-D-aspartate receptors depend on subunit composition. Eur. J. Pharmacol. 268 (1994) 335-345
26. Liu L., Wong T.P., Pozza M.F., Lingenhoehl K., Wang Y., Sheng M., Auberson Y.P., and Wang Y.T. Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity. Science 304 (2004) 1021-1024
27. Lu H.C., Gonzalez E., and Crair M.C. Barrel cortex critical period plasticity is independent of changes in NMDA receptor subunit composition. Neuron 32 (2001) 619-634
28. Maffei A., Nataraj K., Nelson S.B., and Turrigiano G.G. Potentiation of cortical inhibition by visual deprivation. Nature 443 (2006) 81-84
29. Massey P.V., Johnson B.E., Moult P.R., Auberson Y.P., Brown M.W., Molnar E., Collingridge G.L., and Bashir Z.I. Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression. J. Neurosci. 24 (2004) 7821-7828
30. Monyer H., Sprengel R., Schoepfer R., Herb A., Higuchi M., Lomeli H., Burnashev N., Sakmann B., and Seeburg P.H. Heteromeric NMDA receptors: molecular and functional distinction of subtypes. Science 256 (1992) 1217-1221
31. Monyer H., Burnashev N., Laurie D.J., Sakmann B., and Seeburg P.H. Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron 12 (1994) 529-540
32. Morikawa E., Mori H., Kiyama Y., Mishina M., Asano T., and Kirino T. Attenuation of focal ischemic brain injury in mice deficient in the epsilon1 (NR2A) subunit of NMDA receptor. J. Neurosci. 18 (1998) 9727-9732
33. Morishita W., Lu W., Smith G.B., Nicoll R.A., Bear M.F., and Malenka R.C. Activation of NR2B-containing NMDA receptors is not required for NMDA receptor-dependent long-term depression. Neuropharmacology 52 (2007) 71-76 10.1016/j.neuropharm.2006.07.005 Published online August 8, 2006
34. Nase G., Weishaupt J., Stern P., Singer W., and Monyer H. Genetic and epigenetic regulation of NMDA receptor expression in the rat visual cortex. Eur. J. Neurosci. 11 (1999) 4320-4326
35. Neyton J., and Paoletti P. Relating NMDA receptor function to receptor subunit composition: limitations of the pharmacological approach. J. Neurosci. 26 (2006) 1331-1333
36. Perez-Otano I., Schulteis C.T., Contractor A., Lipton S.A., Trimmer J.S., Sucher N.J., and Heinemann S.F. Assembly with the NR1 subunit is required for surface expression of NR3A-containing NMDA receptors. J. Neurosci. 21 (2001) 1228-1237
37. Philpot B.D., Sekhar A.K., Shouval H.Z., and Bear M.F. Visual experience and deprivation bidirectionally modify the composition and function of NMDA receptors in visual cortex. Neuron 29 (2001) 157-169
38. Philpot B.D., Weisberg M.P., Ramos M.S., Sawtell N.B., Tang Y.P., Tsien J.Z., and Bear M.F. Effect of transgenic overexpression of NR2B on NMDA receptor function and synaptic plasticity in visual cortex. Neuropharmacology 41 (2001) 762-770
39. Philpot B.D., Espinosa J.S., and Bear M.F. Evidence for altered NMDA receptor function as a basis for metaplasticity in visual cortex. J. Neurosci. 23 (2003) 5583-5588
40. Priestley T., Laughton P., Myers J., Le Bourdelles B., Kerby J., and Whiting P.J. Pharmacological properties of recombinant human N-methyl-D-aspartate receptors comprising NR1a/NR2A and NR1a/NR2B subunit assemblies expressed in permanently transfected mouse fibroblast cells. Mol. Pharmacol. 48 (1995) 841-848
41. Prybylowski K., Rumbaugh G., Wolfe B.B., and Vicini S. Increased exon 5 expression alters extrasynaptic NMDA receptors in cerebellar neurons. J. Neurochem. 75 (2000) 1140-1146
42. Quinlan E.M., Olstein D.H., and Bear M.F. Bidirectional, experience-dependent regulation of N-methyl-D-aspartate receptor subunit composition in the rat visual cortex during postnatal development. Proc. Natl. Acad. Sci. USA 96 (1999) 12876-12880
43. Quinlan E.M., Philpot B.D., Huganir R.L., and Bear M.F. Rapid, experience-dependent expression of synaptic NMDA receptors in visual cortex in vivo. Nat. Neurosci. 2 (1999) 352-357
44. Rumbaugh G., Prybylowski K., Wang J.F., and Vicini S. Exon 5 and spermine regulate deactivation of NMDA receptor subtypes. J. Neurophysiol. 83 (2000) 1300-1306
45. Sakimura K., Kutsuwada T., Ito I., Manabe T., Takayama C., Kushiya E., Yagi T., Aizawa S., Inoue Y., Sugiyama H., et al. Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit. Nature 373 (1995) 151-155
46. Sans N., Petralia R.S., Wang Y.X., Blahos II J., Hell J.W., and Wenthold R.J. A developmental change in NMDA receptor-associated proteins at hippocampal synapses. J. Neurosci. 20 (2000) 1260-1271
47. Sheng M., Cummings J., Roldan L.A., Jan Y.N., and Jan L.Y. Changing subunit composition of heteromeric NMDA receptors during development of rat cortex. Nature 368 (1994) 144-147
48. Shi J., Townsend M., and Constantine-Paton M. Activity-dependent induction of tonic calcineurin activity mediates a rapid developmental downregulation of NMDA receptor currents. Neuron 28 (2000) 103-114
49. 2+] signaling in individual hippocampal dendritic spines. J. Neurosci. 25 (2005) 6037-6046
50. Steele P.M., and Mauk M.D. Inhibitory control of LTP and LTD: stability of synapse strength. J. Neurophysiol. 81 (1999) 1559-1566
51. Steigerwald F., Schulz T.W., Schenker L.T., Kennedy M.B., Seeburg P.H., and Kohr G. C-Terminal truncation of NR2A subunits impairs synaptic but not extrasynaptic localization of NMDA receptors. J. Neurosci. 20 (2000) 4573-4581
52. Stocca G., and Vicini S. Increased contribution of NR2A subunit to synaptic NMDA receptors in developing rat cortical neurons. J. Physiol. 507 (1998) 13-24
53. Tsumoto T., Hagihara K., Sato H., and Hata Y. NMDA receptors in the visual cortex of young kittens are more effective than those of adult cats. Nature 327 (1987) 513-514
54. Vicini S., Wang J.F., Li J.H., Zhu W.J., Wang Y.H., Luo J.H., Wolfe B.B., and Grayson D.R. Functional and pharmacological differences between recombinant N-methyl-D-aspartate receptors. J. Neurophysiol. 79 (1998) 555-566
55. Vissel B., Krupp J.J., Heinemann S.F., and Westbrook G.L. Intracellular domains of NR2 alter calcium-dependent inactivation of N-methyl-D-aspartate receptors. Mol. Pharmacol. 61 (2002) 595-605
56. Watanabe M., Inoue Y., Sakimura K., and Mishina M. Distinct spatio-temporal distributions of the NMDA receptor channel subunit mRNAs in the brain. Ann. N Y Acad. Sci. 707 (1993) 463-466
57. Weitlauf C., Honse Y., Auberson Y.P., Mishina M., Lovinger D.M., and Winder D.G. Activation of NR2A-containing NMDA receptors is not obligatory for NMDA receptor-dependent long-term potentiation. J. Neurosci. 25 (2005) 8386-8390
58. Yoshii A., Sheng M.H., and Constantine-Paton M. Eye opening induces a rapid dendritic localization of PSD-95 in central visual neurons. Proc. Natl. Acad. Sci. USA 100 (2003) 1334-1339
59. Zeng H., Chattarji S., Barbarosie M., Rondi-Reig L., Philpot B.D., Miyakawa T., Bear M.F., and Tonegawa S. Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory. Cell 107 (2001) 617-629
60. Zhao M.G., Toyoda H., Lee Y.S., Wu L.J., Ko S.W., Zhang X.H., Jia Y., Shum F., Xu H., Li B.M., et al. Roles of NMDA NR2B subtype receptor in prefrontal long-term potentiation and contextual fear memory. Neuron 47 (2005) 859-872