Assembly with the NR1 subunit is required for surface expression of NR3A-containing NMDA receptors

Journal of Neuroscience

Volumn 21, Issue 4, 2001, Pages 1228-1237

  Pérez Otaño, Isabel ^a   Schulteis, Christine T ^a   Contractor, Anis ^a   Lipton, Stuart A ^b   Trimmer, James S ^c   Sucher, Nikolaus J ^d   Heinemann, Stephen F ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b BURNHAM INSTITUTE   (United States)

^c STONY BROOK UNIVERSITY   (United States)

^d HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

Assembly; Calcium permeability; Glutamate; NMDA receptor; NR3A; Single channel; Surface expression

Indexed keywords

CALCIUM CHANNEL; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RECEPTOR SUBUNIT;

ARTICLE; CONTROLLED STUDY; EMBRYO; ENDOPLASMIC RETICULUM; GENE CLUSTER; GENE EXPRESSION; GENE LOCATION; GENE TARGETING; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; MEMBRANE PERMEABILITY; MULTIGENE FAMILY; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN PROTEIN INTERACTION;

EID: 0035866095     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-04-01228.2001     Document Type: Article

References (43)

1. A synaptic model of memory: Long-term potentiation in the hippocampus
2. Fractional calcium currents through recombinant GluR channels of the NMDA, AMPA and kainate receptor subtypes
3. Glutamate neurotoxicity and diseases of the nervous system
4. Cloning and characterization of X-1: A developmentally regulated member of a novel class of ionotropic glutamate receptor family
5. Fitting and statistical analysis of single channels
6. Patterned activity, synaptic convergence, and the NMDA receptor in developing visual pathways
7. Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A
8. The glutamate receptor ion channels
9. Analysis of mutation in human cells by using an Epstein-Barr viral shuttle system
10. Splice variants of the N-methyl-D-aspartate receptor NR1 identify domains involved in regulation by polyamines and protein kinase C
11. Inactivation of NMDA receptors by direct interaction of calmodulin with NR1 subunit
12. Setting the standards: Quality control in the secretory pathway
13. Assembly of GABAA receptors composed of alpha1 and beta2 subunits in both cultured neurons and fibroblasts
14. Ion-channel assembly
15. Differential surface expression and phosphorylation of the N-methyl-D-aspartate receptor subunits NR1 and NR2 in cultured hippocampal neurons
16. Zinc potentiates agonist-induced currents at certain splice variants of the NMDA receptor
17. N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1
18. Heteromultimerization and NMDA receptor-clustering activity of Chapsyn-110, a member of the PSD-95 family of proteins
19. Brefeldin A: Insights into the control of membrane traffic and organelle structure
20. Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95
21. Yotiao, a novel protein of neuromuscular junction and brain that interacts with specific splice variants of NMDA receptor subunit NR1
22. Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin A suggests an ER recycling pathway
23. The majority of N-methyl-D-aspartate receptor complexes in adult rat cerebral cortex contain at least three different subunits (NR1/NR2A/NR2B)
24. Long-term potentiation - A decade of progress?
25. Subunit composition determines Kv1 potassium channel surface expression
26. Permeation and block of N-methyl-Daspartic acid receptor channels by divalent cations in mouse cultured central neurones
27. Cell surface expression of the human N-methyl-D-aspartate receptor subunit 1a requires the co-expression of the NR2A subunit in transfected cells
28. Assembly intracellular targeting and cell surface expression of the human N-methyl-D-aspartate receptor subunits NR1a and NR2A in transfected cells
29. Heteromeric NMDA receptors: Molecular and functional distinction of subtypes
30. Developmental and regional expression in the rat brain and functional properties of four NMDA receptors
31. Potassium channel alpha and beta subunits assemble in the endoplasmic reticulum
32. Correction for liquid junction potentials in patch clamp experiments
33. Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases
34. Analysis of early events in acetylcholine receptor assembly
35. Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein
36. 2+ influx and reversal potentials in recombinant N-methyl-D-aspartate receptor channels
37. Single channel conductances of NMDA receptors expressed from cloned cDNAs: Comparison with native receptors
38. Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins
39. Developmental and regional expression pattern of a novel NMDA receptor-like subunit (NMDAR-L) in the rodent brain
40. The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory
41. Transmembrane topology of two kainate receptor subunits revealed by N-glycosylation
42. Competitive binding of alpha-actinin and calmodulin to the NMDA receptor
43. A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels