Evidence for altered NMDA receptor function as a basis for metaplasticity in visual cortex

Journal of Neuroscience

Volumn 23, Issue 13, 2003, Pages 5583-5588

  Philpot, Benjamin D ^a   Espinosa, Juan S ^a,b   Bear, Mark F ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

APV; BCM theory; Dark rearing; Metaplasticity; NMDA receptor; Visual cortex

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CONTROLLED STUDY; DARKNESS; DOWN REGULATION; FREQUENCY MODULATION; HYPOTHESIS; IN VIVO STUDY; LIGHT EXPOSURE; LONG TERM POTENTIATION; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; RECEPTOR BLOCKING; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SENSORY DEPRIVATION; SYNAPTIC POTENTIAL; VISUAL CORTEX; VISUAL STIMULATION;

EID: 0038045581     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-13-05583.2003     Document Type: Article

References (25)

1. Bear MF (1998) The role of LTD and LTP in development and learning. In: Mechanistic relationships between development and learning (Carew TJ, Menzel R, Shatz CJ, eds), pp 205-225. New York: Wiley.
2. Bear MF, Abraham WC (1996) Long-term depression in hippocampus. Annu Rev Neurosci 19:437-462.
3. Bear MF, Cooper LN, Ebner FF (1987) A physiological basis for a theory of synaptic modification. Science 237:42-48.
4. Carmignoto G, Vicini S (1992) Activity-dependent decrease in NMDA receptor responses during development of the visual cortex. Science 258:1007-1011.
5. Castellani GC, Quinlan EM, Cooper LN, Shouval HZ (2001) A biophysical model of bidirectional synaptic plasticity: dependence on AMPA and NMDA receptors. Proc Natl Acad Sci USA 98:12772-12777.
6. Connor JA, Cormier RJ (2000) Cumulative effects of glutamate microstimulation on Ca (2+) responses of CA1 hippocampal pyramidal neurons in slice. J Neurophysiol 83:90-98.
7. 2+ signalling requirements for long-term depression in the hippocampus. Neuron 16:825-833.
8. Fox K, Daw N, Sato H, Czepita D (1991) Dark-rearing delays the loss of NMDA-receptor function in kitten visual cortex. Nature 350:342-344.
9. 2+ concentration exploring possible bases for a sliding modification threshold. Proc Natl Acad Sci USA 91:3941-3945.
10. Huber KM, Sawtell NB, Bear MF (1998) Brain-derived neurotrophic factor alters the synaptic modification threshold in visual cortex. Neuropharmacology 37:571-579.
11. Ikegaya Y, Ishizaka Y, Matsuki N (2002) BDNF attenuates hippocampal LTD via activation of phospholipase C: implications for a vertical shift in the frequency-response curve of synaptic plasticity. Eur J Neurosci 16:145-148.
12. Katz LC, Shatz CJ (1996) Synaptic activity and the construction of cortical circuits. Science 274:1133-1138.
13. Kirkwood A, Bear MF (1994) Homosynaptic long-term depression in the visual cortex. J Neurosci 14:3404-3412.
14. Kirkwood A, Dudek SM, Gold JT, Aizenman CD, Bear MF (1993) Common forms of synaptic plasticity in the hippocampus and neocortex in vitro. Science 260:1518-1521.
15. Kirkwood A, Rioult MG, Bear MF (1996) Experience-dependent modification of synaptic plasticity in visual cortex. Nature 381:526-528.
16. Krucker T, Siggins GR, McNamara RK, Lindsley KA, Dao A, Allison DW, De Lecea L, Lovenberg TW, Sutcliffe JG, Gerendasy DD (2002) Targeted disruption of RC3 reveals a calmodulin-based mechanism for regulating metaplasticity in the hippocampus. J Neurosci 22:5525-5535.
17. Mulkey RM, Endo S, Shenolikar S, Malenka RC (1994) Involvement of a calcineurin/inhibitor-1 phosphatase cascade in hippocampal long-term depression. Nature 369:486-488.
18. 2+]i needed to trigger LTD and LTP. Neuron 16:619-629.
19. Ngezahayo A, Schachner M, Artola A (2000) Synaptic activity modulates the induction of bidirectional synaptic changes in adult mouse hippocampus. J Neurosci 20:2451-2458.
20. Philpot BD, Sekhar AK, Shouval HZ, Bear MF (2001a) Visual experience and deprivation bidirectionally modify the composition and function of NMDA receptors in visual cortex. Neuron 29:157-169.
21. Philpot BD, Weisberg MP, Ramos MS, Sawtell NB, Tang YP, Tsien JZ, Bear MF (2001b) Effect of transgenic overexpression of NR2B on NMDA receptor function and synaptic plasticity in visual cortex. Neuropharmacology 41:762-770.
22. Quinlan EM, Philpot BD, Huganir RL, Bear MF (1999) Rapid, experience-dependent expression of synaptic NMDA receptors in visual cortex in vivo. Nat Neurosci 2:352-357.
23. Shouval HZ, Bear MF, Cooper LN (2002) A unified model of NMDA receptor-dependent bidirectional synaptic plasticity. Proc Natl Acad Sci USA 99:10831-10836.
24. Steele PM, Mauk MD (1999) Inhibitory control of LTP and LTD: stability of synapse strength. J Neurophysiol 81:1559-1566.
25. Tsumoto T, Hagihara K, Sato H, Hata Y (1987) NMDA receptors in the visual cortex of young kittens are more effective than those of adult cats. Nature 327:513-514.