Parkin is an E3 ubiquitin-ligase for normal and mutant ataxin-2 and prevents ataxin-2-induced cell death

Experimental Neurology

Volumn 203, Issue 2, 2007, Pages 531-541

  Huynh, Duong P ^a,b   Nguyen, Dung T ^a   Pulst Korenberg, Johannes B ^a   Brice, Alexis ^c   Pulst, Stefan M ^a,b  

^a BURNS AND ALLEN RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

AR JP; Ataxin 2; Parkin; Parkinson's disease; SCA2

Indexed keywords

ATAXIN 2; GENE PRODUCT; MUTANT PROTEIN; PARKIN; POLYGLUTAMINE; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CELL DEATH; CELL LABELING; CELL STRAIN; CELL STRUCTURE; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; GENE MUTATION; GOLGI COMPLEX; HUMAN; HUMAN CELL; MOUSE; NERVE DEGENERATION; NONHUMAN; PARKINSONISM; PHENOTYPE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN VARIANT; PURKINJE CELL; REGULATORY MECHANISM; SPINOCEREBELLAR DEGENERATION; STEADY STATE; SUBSTANTIA NIGRA; WESTERN BLOTTING; WILD TYPE;

EID: 33846545106     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2006.09.009     Document Type: Article

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