메뉴 건너뛰기




Volumn 26, Issue 44, 2006, Pages 11333-11341

Proteasome inhibition triggers activity-dependent increase in the size of the recycling vesicle pool in cultured hippocampal neurons

Author keywords

FM assay; Hippocampus; Homeostasis; Proteasome; Synaptic transmission; Vesicle pools

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; DYE; EPOXOMICIN; LACTACYSTIN BETA LACTONE; PROTEASOME; STYRYLPYRIDINIUM; UNCLASSIFIED DRUG; CLASTO-LACTACYSTIN BETA-LACTONE; LACTONE;

EID: 33750959090     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1684-06.2006     Document Type: Article
Times cited : (82)

References (60)
  • 1
    • 0037441501 scopus 로고    scopus 로고
    • Synaptic Drosophila UNC-13 is regulated by antagonistic G-protein pathways via a proteasome-dependent degradation mechanism
    • Aravamudan B, Broadie K (2003) Synaptic Drosophila UNC-13 is regulated by antagonistic G-protein pathways via a proteasome-dependent degradation mechanism. J Neurobiol 54:417-438.
    • (2003) J Neurobiol , vol.54 , pp. 417-438
    • Aravamudan, B.1    Broadie, K.2
  • 2
    • 0035829729 scopus 로고    scopus 로고
    • Phosphorylation and local presynaptic protein synthesis in calcium- and calcineurin-dependent induction of crayfish long-term facilitation
    • Beaumont V, Zhong N, Fletcher R, Froemke RC, Zucker RS (2001) Phosphorylation and local presynaptic protein synthesis in calcium- and calcineurin-dependent induction of crayfish long-term facilitation. Neuron 32:489-501.
    • (2001) Neuron , vol.32 , pp. 489-501
    • Beaumont, V.1    Zhong, N.2    Fletcher, R.3    Froemke, R.C.4    Zucker, R.S.5
  • 5
    • 0026584039 scopus 로고
    • Optical analysis of synaptic vesicle recycling at the frog neuromuscular junction
    • Betz WJ, Bewick GS (1992) Optical analysis of synaptic vesicle recycling at the frog neuromuscular junction. Science 255:200-203.
    • (1992) Science , vol.255 , pp. 200-203
    • Betz, W.J.1    Bewick, G.S.2
  • 6
    • 25844512787 scopus 로고    scopus 로고
    • Synaptic protein degradation by the ubiquitin proteasome system
    • Bingol B, Schuman EM (2005) Synaptic protein degradation by the ubiquitin proteasome system. Curr Opin Neurobiol 15:536-541.
    • (2005) Curr Opin Neurobiol , vol.15 , pp. 536-541
    • Bingol, B.1    Schuman, E.M.2
  • 7
    • 33745593049 scopus 로고    scopus 로고
    • Activity-dependent dynamics and sequestration of proteasomes in dendritic spines
    • Bingol B, Schuman EM (2006) Activity-dependent dynamics and sequestration of proteasomes in dendritic spines. Nature 441:1144-1148.
    • (2006) Nature , vol.441 , pp. 1144-1148
    • Bingol, B.1    Schuman, E.M.2
  • 8
    • 0037014445 scopus 로고    scopus 로고
    • Ubiquitin and AP180 regulate the abundance of GLR-1 glutamate receptors at postsynaptic elements in C. elegans
    • Burbea M, Dreier L, Dittman JS, Grunwald ME, Kaplan JM (2002) Ubiquitin and AP180 regulate the abundance of GLR-1 glutamate receptors at postsynaptic elements in C. elegans. Neuron 35:107-120.
    • (2002) Neuron , vol.35 , pp. 107-120
    • Burbea, M.1    Dreier, L.2    Dittman, J.S.3    Grunwald, M.E.4    Kaplan, J.M.5
  • 9
    • 2942752010 scopus 로고    scopus 로고
    • Multiple roles for the active zone protein RIM1alpha in late stages of neurotransmitter release
    • Calakos N, Schoch S, Sudhof TC, Malenka RC (2004) Multiple roles for the active zone protein RIM1alpha in late stages of neurotransmitter release. Neuron 42:889-896.
    • (2004) Neuron , vol.42 , pp. 889-896
    • Calakos, N.1    Schoch, S.2    Sudhof, T.C.3    Malenka, R.C.4
  • 11
    • 0037144498 scopus 로고    scopus 로고
    • Staring, a novel E3 ubiquitin-protein ligase that targets syntaxin 1 for degradation
    • Chin LS, Vavalle JP, Li L (2002) Staring, a novel E3 ubiquitin-protein ligase that targets syntaxin 1 for degradation. J Biol Chem 277:35071-35079.
    • (2002) J Biol Chem , vol.277 , pp. 35071-35079
    • Chin, L.S.1    Vavalle, J.P.2    Li, L.3
  • 12
    • 0037672253 scopus 로고    scopus 로고
    • Synaptic plasticity: Importance of proteasome-mediated protein turnover
    • Cline H (2003) Synaptic plasticity: importance of proteasome-mediated protein turnover. Curr Biol 13:R514-R516.
    • (2003) Curr Biol , vol.13
    • Cline, H.1
  • 15
    • 0026311694 scopus 로고
    • Statistical data analysis in the computer age
    • Efron B, Tibshirani R (1991) Statistical data analysis in the computer age. Science 253:390-395.
    • (1991) Science , vol.253 , pp. 390-395
    • Efron, B.1    Tibshirani, R.2
  • 16
    • 0037374587 scopus 로고    scopus 로고
    • Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome system
    • Ehlers MD (2003) Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome system. Nat Neurosci 6:231-242.
    • (2003) Nat Neurosci , vol.6 , pp. 231-242
    • Ehlers, M.D.1
  • 17
    • 0028180516 scopus 로고
    • A beta-lactone related to lactacystin induces neurite outgrowth in a neuroblastoma cell line and inhibits cell cycle progression in an osteosarcoma cell line
    • Fenteany G, Standaert RF, Reichard GA, Corey EJ, Schreiber SL (1994) A beta-lactone related to lactacystin induces neurite outgrowth in a neuroblastoma cell line and inhibits cell cycle progression in an osteosarcoma cell line. Proc Natl Acad Sci USA 91:3358-3362.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3358-3362
    • Fenteany, G.1    Standaert, R.F.2    Reichard, G.A.3    Corey, E.J.4    Schreiber, S.L.5
  • 18
    • 0032570593 scopus 로고    scopus 로고
    • Melatonin production: Proteasomal proteolysis in serotonin N-acetyltransferase regulation
    • Gastel JA, Roseboom PH, Rinaldi PA, Weller JL, Klein DC (1998) Melatonin production: proteasomal proteolysis in serotonin N-acetyltransferase regulation. Science 279:1358-1360.
    • (1998) Science , vol.279 , pp. 1358-1360
    • Gastel, J.A.1    Roseboom, P.H.2    Rinaldi, P.A.3    Weller, J.L.4    Klein, D.C.5
  • 19
    • 0036680479 scopus 로고    scopus 로고
    • Axonal and presynaptic protein synthesis: New insights into the biology of the neuron
    • Giuditta A, Kaplan BB, van Minnen J, Alvarez J, Koenig E (2002) Axonal and presynaptic protein synthesis: new insights into the biology of the neuron. Trends Neurosci 25:400-404.
    • (2002) Trends Neurosci , vol.25 , pp. 400-404
    • Giuditta, A.1    Kaplan, B.B.2    Van Minnen, J.3    Alvarez, J.4    Koenig, E.5
  • 20
    • 0036083396 scopus 로고    scopus 로고
    • The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
    • Glickman MH, Ciechanover A (2002) The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev 82:373-428.
    • (2002) Physiol Rev , vol.82 , pp. 373-428
    • Glickman, M.H.1    Ciechanover, A.2
  • 21
    • 0035940483 scopus 로고    scopus 로고
    • Visualizing recycling synaptic vesicles in hippocampal neurons by FM 1-43 photo-conversion
    • Harata N, Ryan TA, Smith SJ, Buchanan J, Tsien RW (2001) Visualizing recycling synaptic vesicles in hippocampal neurons by FM 1-43 photo-conversion. Proc Natl Acad Sci USA 98:12748-12753.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 12748-12753
    • Harata, N.1    Ryan, T.A.2    Smith, S.J.3    Buchanan, J.4    Tsien, R.W.5
  • 22
    • 4143112402 scopus 로고    scopus 로고
    • Ubiquitin-proteasome-mediated local protein degradation and synaptic plasticity
    • Hegde AN (2004) Ubiquitin-proteasome-mediated local protein degradation and synaptic plasticity. Prog Neurobiol 73:311-357.
    • (2004) Prog Neurobiol , vol.73 , pp. 311-357
    • Hegde, A.N.1
  • 23
    • 0141995596 scopus 로고    scopus 로고
    • The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI
    • Huynh DP, Scoles DR, Nguyen D, Pulst SM (2003) The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI. Hum Mol Genet 12:2587-2597.
    • (2003) Hum Mol Genet , vol.12 , pp. 2587-2597
    • Huynh, D.P.1    Scoles, D.R.2    Nguyen, D.3    Pulst, S.M.4
  • 24
    • 32544446276 scopus 로고    scopus 로고
    • Regulation of the neuronal proteasome by Zif268 (Egr1)
    • James AB, Conway AM, Morris BJ (2006) Regulation of the neuronal proteasome by Zif268 (Egr1). J Neurosci 26:1624-1634.
    • (2006) J Neurosci , vol.26 , pp. 1624-1634
    • James, A.B.1    Conway, A.M.2    Morris, B.J.3
  • 26
    • 9244263049 scopus 로고    scopus 로고
    • The anaphase-promoting complex regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of C. elegans
    • Juo P, Kaplan JM (2004) The anaphase-promoting complex regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of C. elegans. Curr Biol 14:2057-2062.
    • (2004) Curr Biol , vol.14 , pp. 2057-2062
    • Juo, P.1    Kaplan, J.M.2
  • 27
    • 33646918035 scopus 로고    scopus 로고
    • Involvement of protein synthesis and degradation in long-term potentiation of Schaffer collateral CA1 synapses
    • Karpova A, Mikhaylova M, Thomas U, Knopfel T, Behnisch T (2006) Involvement of protein synthesis and degradation in long-term potentiation of Schaffer collateral CA1 synapses. J Neurosci 26:4949-4955.
    • (2006) J Neurosci , vol.26 , pp. 4949-4955
    • Karpova, A.1    Mikhaylova, M.2    Thomas, U.3    Knopfel, T.4    Behnisch, T.5
  • 29
    • 0034864799 scopus 로고    scopus 로고
    • Proteasome inhibitors: From research tools to drug candidates
    • Kisselev AF, Goldberg AL (2001) Proteasome inhibitors: from research tools to drug candidates. Chem Biol 8:739-758.
    • (2001) Chem Biol , vol.8 , pp. 739-758
    • Kisselev, A.F.1    Goldberg, A.L.2
  • 31
    • 0033103353 scopus 로고    scopus 로고
    • The optically determined size of exo/endo cycling vesicle pool correlates with the quantal content at the neuromuscular junction of Drosophila larvae
    • Kuromi H, Kidokoro Y (1999) The optically determined size of exo/endo cycling vesicle pool correlates with the quantal content at the neuromuscular junction of Drosophila larvae. J Neurosci 19:1557-1565.
    • (1999) J Neurosci , vol.19 , pp. 1557-1565
    • Kuromi, H.1    Kidokoro, Y.2
  • 32
    • 0033667467 scopus 로고    scopus 로고
    • Tetanic stimulation recruits vesicles from reserve pool via a cAMP-mediated process in Drosophila synapses
    • Kuromi H, Kidokoro Y (2000) Tetanic stimulation recruits vesicles from reserve pool via a cAMP-mediated process in Drosophila synapses. Neuron 27:133-143.
    • (2000) Neuron , vol.27 , pp. 133-143
    • Kuromi, H.1    Kidokoro, Y.2
  • 33
    • 3042578334 scopus 로고    scopus 로고
    • Two synaptic vesicle pools, vesicle recruitment and replenishment of pools at the Drosophila neuromuscular junction
    • Kuromi H, Kidokoro Y (2003) Two synaptic vesicle pools, vesicle recruitment and replenishment of pools at the Drosophila neuromuscular junction. J Neurocytol 32:551-565.
    • (2003) J Neurocytol , vol.32 , pp. 551-565
    • Kuromi, H.1    Kidokoro, Y.2
  • 34
    • 15244339852 scopus 로고    scopus 로고
    • Exocytosis and endocytosis of synaptic vesicles and functional roles of vesicle pools: Lessons from the Drosophila neuromuscular junction
    • Kuromi H, Kidokoro Y (2005) Exocytosis and endocytosis of synaptic vesicles and functional roles of vesicle pools: lessons from the Drosophila neuromuscular junction. Neuroscientist 11:138-147.
    • (2005) Neuroscientist , vol.11 , pp. 138-147
    • Kuromi, H.1    Kidokoro, Y.2
  • 35
    • 14844282749 scopus 로고    scopus 로고
    • Evidence that insulin secretion influences SNAP-25 through proteasomal activation
    • Ma Z, Portwood N, Foss A, Grill V, Bjorklund A (2005) Evidence that insulin secretion influences SNAP-25 through proteasomal activation. Biochem Biophys Res Commun 329:1118-1126.
    • (2005) Biochem Biophys Res Commun , vol.329 , pp. 1118-1126
    • Ma, Z.1    Portwood, N.2    Foss, A.3    Grill, V.4    Bjorklund, A.5
  • 36
    • 3042794162 scopus 로고    scopus 로고
    • Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease
    • McNaught KS, Perl DP, Brownell AL, Olanow CW (2004) Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease. Ann Neurol 56:149-162.
    • (2004) Ann Neurol , vol.56 , pp. 149-162
    • McNaught, K.S.1    Perl, D.P.2    Brownell, A.L.3    Olanow, C.W.4
  • 37
    • 0037179795 scopus 로고    scopus 로고
    • New roles for ubiquitin in the assembly and function of neuronal circuits
    • Murphey RK, Godenschwege TA (2002) New roles for ubiquitin in the assembly and function of neuronal circuits. Neuron 36:5-8.
    • (2002) Neuron , vol.36 , pp. 5-8
    • Murphey, R.K.1    Godenschwege, T.A.2
  • 39
    • 32344440647 scopus 로고    scopus 로고
    • Synapse formation and plasticity: Recent insights from the perspective of the ubiquitin proteasome system
    • Patrick GN (2006) Synapse formation and plasticity: recent insights from the perspective of the ubiquitin proteasome system. Curr Opin Neurobiol 16:90-94.
    • (2006) Curr Opin Neurobiol , vol.16 , pp. 90-94
    • Patrick, G.N.1
  • 40
    • 0344663966 scopus 로고    scopus 로고
    • Ubiquitin-mediated proteasome activity is required for agonist-induced endocytosis of GluRs
    • Patrick GN, Bingol B, Weld HA, Schuman EM (2003) Ubiquitin-mediated proteasome activity is required for agonist-induced endocytosis of GluRs. Curr Biol 13:2073-2081.
    • (2003) Curr Biol , vol.13 , pp. 2073-2081
    • Patrick, G.N.1    Bingol, B.2    Weld, H.A.3    Schuman, E.M.4
  • 41
    • 0346874341 scopus 로고    scopus 로고
    • Synaptotagmin I is necessary for compensatory synaptic vesicle endocytosis in vivo
    • Poskanzer KE, Marek KW, Sweeney ST, Davis GW (2003) Synaptotagmin I is necessary for compensatory synaptic vesicle endocytosis in vivo. Nature 426:559-563.
    • (2003) Nature , vol.426 , pp. 559-563
    • Poskanzer, K.E.1    Marek, K.W.2    Sweeney, S.T.3    Davis, G.W.4
  • 42
    • 0033635239 scopus 로고    scopus 로고
    • Rapid reuse of readily releasable pool vesicles at hippocampal synapses
    • Pyle JL, Kavalali ET, Piedras-Renteria ES, Tsien RW (2000) Rapid reuse of readily releasable pool vesicles at hippocampal synapses. Neuron 28:221-231.
    • (2000) Neuron , vol.28 , pp. 221-231
    • Pyle, J.L.1    Kavalali, E.T.2    Piedras-Renteria, E.S.3    Tsien, R.W.4
  • 43
    • 0029621898 scopus 로고
    • A proteasome activator subunit binds calcium
    • Realini C, Rechsteiner M (1995) A proteasome activator subunit binds calcium. J Biol Chem 270:29664-29667.
    • (1995) J Biol Chem , vol.270 , pp. 29664-29667
    • Realini, C.1    Rechsteiner, M.2
  • 44
    • 0035102504 scopus 로고    scopus 로고
    • A developmental switch in neurotransmitter flux enhances synaptic efficacy by affecting AMPA receptor activation
    • Renger JJ, Egles C, Liu G (2001) A developmental switch in neurotransmitter flux enhances synaptic efficacy by affecting AMPA receptor activation. Neuron 29:469-484.
    • (2001) Neuron , vol.29 , pp. 469-484
    • Renger, J.J.1    Egles, C.2    Liu, G.3
  • 45
    • 1642296166 scopus 로고    scopus 로고
    • The structural organization of the readily releasable pool of synaptic vesicles
    • Rizzoli SO, Betz WJ (2004) The structural organization of the readily releasable pool of synaptic vesicles. Science 303:2037-2039.
    • (2004) Science , vol.303 , pp. 2037-2039
    • Rizzoli, S.O.1    Betz, W.J.2
  • 46
    • 0037204063 scopus 로고    scopus 로고
    • Differential control of vesicle priming and short-term plasticity by Munc13 isoforms
    • Rosenmund C, Sigler A, Augustin I, Reim K, Brose N, Rhee JS (2002) Differential control of vesicle priming and short-term plasticity by Munc13 isoforms. Neuron 33:411-424.
    • (2002) Neuron , vol.33 , pp. 411-424
    • Rosenmund, C.1    Sigler, A.2    Augustin, I.3    Reim, K.4    Brose, N.5    Rhee, J.S.6
  • 47
    • 0027487057 scopus 로고
    • The kinetics of synaptic vesicle recycling measured at single presynaptic boutons
    • Ryan TA, Reuter H, Wendland B, Schweizer FE, Tsien RW, Smith SJ (1993) The kinetics of synaptic vesicle recycling measured at single presynaptic boutons. Neuron 11:713-724.
    • (1993) Neuron , vol.11 , pp. 713-724
    • Ryan, T.A.1    Reuter, H.2    Wendland, B.3    Schweizer, F.E.4    Tsien, R.W.5    Smith, S.J.6
  • 48
    • 0035095914 scopus 로고    scopus 로고
    • Morphological correlates of functionally defined synaptic vesicle populations
    • Schikorski T, Stevens CF (2001) Morphological correlates of functionally defined synaptic vesicle populations. Nat Neurosci 4:391-395.
    • (2001) Nat Neurosci , vol.4 , pp. 391-395
    • Schikorski, T.1    Stevens, C.F.2
  • 49
    • 0033792485 scopus 로고    scopus 로고
    • Selective adrenergic/cyclic AMP-dependent switch-off of proteasomal proteolysis alone switches on neural signal transduction: An example from the pineal gland
    • Schomerus C, Korf HW, Laedtke E, Weller JL, Klein DC (2000) Selective adrenergic/cyclic AMP-dependent switch-off of proteasomal proteolysis alone switches on neural signal transduction: an example from the pineal gland. J Neurochem 75:2123-2132.
    • (2000) J Neurochem , vol.75 , pp. 2123-2132
    • Schomerus, C.1    Korf, H.W.2    Laedtke, E.3    Weller, J.L.4    Klein, D.C.5
  • 51
    • 0141653894 scopus 로고    scopus 로고
    • Acute changes in short-term plasticity at synapses with elevated levels of neuronal calcium sensor-1
    • Sippy T, Cruz-Martin A, Jeromin A, Schweizer FE (2003) Acute changes in short-term plasticity at synapses with elevated levels of neuronal calcium sensor-1. Nat Neurosci 6:1031-1038.
    • (2003) Nat Neurosci , vol.6 , pp. 1031-1038
    • Sippy, T.1    Cruz-Martin, A.2    Jeromin, A.3    Schweizer, F.E.4
  • 52
    • 0037737757 scopus 로고    scopus 로고
    • The ubiquitin proteasome system acutely regulates presynaptic protein turnover and synaptic efficacy
    • Speese SD, Trotta N, Rodesch CK, Aravamudan B, Broadie K (2003) The ubiquitin proteasome system acutely regulates presynaptic protein turnover and synaptic efficacy. Curr Biol 13:899-910.
    • (2003) Curr Biol , vol.13 , pp. 899-910
    • Speese, S.D.1    Trotta, N.2    Rodesch, C.K.3    Aravamudan, B.4    Broadie, K.5
  • 53
    • 25644446864 scopus 로고    scopus 로고
    • Dieldrin induces ubiquitin-proteasome dysfunction in alphasynuclein overexpressing dopaminergic neuronal cells and enhances susceptibility to apoptotic cell death
    • Sun F, Anantharam V, Latchoumycandane C, Kanthasamy A, Kanthasamy AG (2005) Dieldrin induces ubiquitin-proteasome dysfunction in alphasynuclein overexpressing dopaminergic neuronal cells and enhances susceptibility to apoptotic cell death. J Pharmacol Exp Ther 315:69-79.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 69-79
    • Sun, F.1    Anantharam, V.2    Latchoumycandane, C.3    Kanthasamy, A.4    Kanthasamy, A.G.5
  • 54
    • 0742323527 scopus 로고    scopus 로고
    • Homeostatic plasticity in the developing nervous system
    • Turrigiano GG, Nelson SB (2004) Homeostatic plasticity in the developing nervous system. Nat Rev Neurosci 5:97-107.
    • (2004) Nat Rev Neurosci , vol.5 , pp. 97-107
    • Turrigiano, G.G.1    Nelson, S.B.2
  • 55
    • 31744444244 scopus 로고    scopus 로고
    • Differential regulation of proteasome activity in the nucleus and the synaptic terminals
    • Upadhya SC, Ding L, Smith TK, Hegde AN (2006) Differential regulation of proteasome activity in the nucleus and the synaptic terminals. Neurochem Int 48:296-305.
    • (2006) Neurochem Int , vol.48 , pp. 296-305
    • Upadhya, S.C.1    Ding, L.2    Smith, T.K.3    Hegde, A.N.4
  • 56
    • 0037155924 scopus 로고    scopus 로고
    • Regulation of synaptophysin degradation by mammalian homologues of seven in absentia
    • Wheeler TC, Chin LS, Li Y, Roudabush FL, Li L (2002) Regulation of synaptophysin degradation by mammalian homologues of seven in absentia. J Biol Chem 277:10273-10282.
    • (2002) J Biol Chem , vol.277 , pp. 10273-10282
    • Wheeler, T.C.1    Chin, L.S.2    Li, Y.3    Roudabush, F.L.4    Li, L.5
  • 58
    • 0033564814 scopus 로고    scopus 로고
    • Early requirement for alpha-SNAP and NSF in the secretory cascade in chromaffin cells
    • Xu T, Ashery U, Burgoyne RD, Neher E (1999) Early requirement for alpha-SNAP and NSF in the secretory cascade in chromaffin cells. EMBO J 18:3293-3304.
    • (1999) EMBO J , vol.18 , pp. 3293-3304
    • Xu, T.1    Ashery, U.2    Burgoyne, R.D.3    Neher, E.4
  • 59
    • 23944438207 scopus 로고    scopus 로고
    • Ubiquitin and protein turnover in synapse function
    • Yi JJ, Ehlers MD (2005) Ubiquitin and protein turnover in synapse function. Neuron 47:629-632.
    • (2005) Neuron , vol.47 , pp. 629-632
    • Yi, J.J.1    Ehlers, M.D.2
  • 60
    • 0037851010 scopus 로고    scopus 로고
    • The ubiquitin proteasome system functions as an inhibitory constraint on synaptic strengthening
    • Zhao Y, Hegde AN, Martin KC (2003) The ubiquitin proteasome system functions as an inhibitory constraint on synaptic strengthening. Curr Biol 13:887-898.
    • (2003) Curr Biol , vol.13 , pp. 887-898
    • Zhao, Y.1    Hegde, A.N.2    Martin, K.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.