Mutations in the cadherin superfamily member gene dachsous cause a tissue polarity phenotype by altering frizzled signaling

Development

Volumn 125, Issue 5, 1998, Pages 959-968

  Adler, Paul N ^a   Charlton, Jeannette ^a   Liu, Jingchun ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Cadherin; dachsous; Drosophila; frizzled signaling; Tissue polarity

Indexed keywords

CADHERIN; MEMBRANE PROTEIN;

ANIMAL TISSUE; ARTICLE; CELL POLARITY; DROSOPHILA; EMBRYO PATTERN FORMATION; GENE MUTATION; HAIR; LIMB DEVELOPMENT; MULTIGENE FAMILY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; BODY PATTERNING; CADHERINS; CELL ADHESION; DROSOPHILA; DROSOPHILA PROTEINS; FRIZZLED RECEPTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, INSECT; INSECT PROTEINS; MEMBRANE PROTEINS; MOSAICISM; MUTATION; PHENOTYPE; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; WING;

ANIMALIA; HEXAPODA;

EID: 0031938970     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Adler, P. N. (1992). The genetic control of tissue polarity in Drosophila. BioEssays 4, 735-741.
2. Adler, P. N., Charlton, J. and Park, W. J. (1994). The Drosophila tissue polarity gene inturned functions prior to wing hair morphogenesis in the regulation of hair polarity and number. Genetics 137, 829-836.
3. Adler, P. N., Krasnow, R. E. and Liu, J. (1997). Tissue polarity points from cells of higher toward cells of lower Frizzled levels. Curr. Biol. 7, 940-949.
4. Bhanot, P., Brink, M., Samos, C. H., Hsieh, J. C., Wang, Y., Macke, J. P., Andrew, D., Nathans, J. and Nusse, R. (1996). Dfz2, a new member of the frizzled family in Drosophila functions as a receptor for Wingless. Nature 382, 225-230.
5. Brunner, E., Peter, O., Schweizer, L. and Basler, K. (1997). Pangolin encodes a Lef-1 homolog that acts downstream of Armadillo to transduce the Wingless signal in Drosophila. Nature 385, 829-833.
6. Clark, H., Brentrup, D., Schneitz, K., Bieber, A., Goiodman, C. and Noll, M. (1995). Dachsous encodes a member of the cadherin superfamily that controls imaginal disc morphogenesis in Drosophila. Genes Dev. 9, 1530-1542.
7. Eaton S. and Cohen, S. (1996). Wnt signal transduction: More than one way to skin a (β)-cat? Trends Cell Biol. 6, 287-280.
8. Funayama, N., Fagotto, F., McCrea, P. and Gumbiner, B. M. (1995). Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling. J. Cell Biol. 128, 959-968.
9. Geiger, B. and Ayalon, O. (1992). Cadherins. Annu. Rev. Cell Biol. 8, 307-332.
10. Golic, K. G. and Lindquist, S. (1989). The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome. Cell 59, 499-509.
11. Gubb, D. (1993). Genes controlling cellular polarity in Drosophila. Development supplement, 269-277.
12. Gubb, D. and Garcia-Bellido, A. (1982). A genetic analysis of the determination of cuticular polarity during development in Drosophila melanogaster. J. Embryol. Exp. Morph. 68, 37-57.
13. +TE into the ck locus. Genetics 91, 54-64.
14. Gumbiner, B. (1995). Signal transduction by β-catenin. Curr. Opin. Cell Biol. 7, 634-640.
15. Heasman, J., Crawford, A., Goldstone, K., Garner-Hamrick, P., Gumbiner, B., McCrea, P., Kinter, C., Noro, C. Y., and Wylie, C. (1994). Overexpression of cadherin and underexpression of β-catenin inhibit dorsal mesoderm induction in early Xenopus embryos. Cell 79, 791-803
16. Held, L. I., Duarte, C. M. and Derakhshanian, K. (1986). Extra tarsal joints and abnormal cuticular polarities in various mutants of Drosophila melanogaster. Roux Arch. 195, 145-157.
17. Ingham. P. W. (1996). Has the quest for a Wnt receptor finally frizzled out. Trends Genet. 12, 382-384.
18. Jones, K. H., Liu, J. and Adler, P. N. (1996). Molecular analysis of EMS induced frizzled mutations in Drosophila melanogaster. Genetics 142, 205-215.
19. Klingensmith, J., Nusse, R. and Perrimon, N. (1994). The Drosophila segment polarity gene disevelled encodes a novel protein required for response to the wingless signal. Genes. Dev. 8, 118-130.
20. Krasnow, R. E., and Adler, P. N. (1994). A single frizzled protein has a dual function in tissue polarity. Development 120, 1883-1893.
21. Krasnow, R. E., Wong, L. L. and Adler, P. N. (1995). Dishevelled is a component of the frizzled signaling pathway in Drosophila. Development 121, 4095-4102.
22. Mahoney, P. A., Weber, U., Onofrechuk, P., Beissmann, H., Bryant, P. J. and Goodman, C. (1991). The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamily. Cell 67, 853-868.
23. Nagafuchi, A. and Takeichi, M. (1988). Cell binding fucntion of E-cadherin is regulated by the cytoplasmic domain. EMBO J. 7, 3679-3684.
24. Orsulic, S. and Peifer, M. (1996). Cell-cell signalling: Wingless lands at last. Curr. Biol. 6, 1363-1367.
25. Park, W. J., Liu, J. and Adler, P. N. (1994). The frizzled gene of Drosophila encodes a membrane protein with an odd number of transmembrane domains. Mech. Dev. 45, 127-137.
26. Park, W. J., Liu, J. and Adler, P. N. (1996). The Drosophila tissue polarity gene inturned acts cell autonomously and encodes a novel protein. Development 122, 961-969.
27. Peifer, M. (1995). Cell adhesion and signal transduction: the Armadillo connection. Trends Cell Biol. 5, 224-229.
28. Peifer, M., Sweeton, D., Casey, M. and Wieschaus, E. (1994). Wingless signal and Zeste-white 3 kinase trigger opposing changes in the intracellular distribution of Armadillo. Development 120, 369-380.
29. Peifer, M. and Wieschaus, E. (1990). The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin. Cell 63, 1167-1178.
30. Peifer, M., Rauskolb, C., Williams, M., Riggleman, B. and Wieschaus, E. (1991). The segment polarity gene armadillo interacts with the wingless signaling pathway in both embryonic and adult pattern formation. Development 111, 1029-1043.
31. Perrimon, N. (1996). Serpentine proteins slither into the Wingless and Hedgehog fields. Cell 86, 512-516.
32. Sanson, B., White, P., and Vincent, J-P (1996). Uncoupling cadherin vbased adhesion from wingless signalling in Drosophila. Nature 383, 627-629.
33. Strutt, D. I., U. Weber and M. Mlodzik (1997). The role of RhoA in tissue polarity and Frizzled signaling. Nature 387, 292-295.
34. Tepass, U., Gruszynski-DeFeo, E., Haag, T. A., Omatyar, L., Torok, T. and Hartenstein, V. (1996). Shotgun encodes Drosophila E-cadherin and is preferentially required during cell rearrangement in the neurectoderm and other morphologically active epithelia. Genes Dev. 10, 672-685.
35. Theisen, J., Purcell, J., Bennett, M., Kansagara, D., Syed, A. and Marsh, L. (1994). dishevelled is required during wingless signaling to establish both cell polarity and cell identity. Development 120, 347-360.
36. Uemura, T., Oda, Hiroki, Kraut, R., Hayashi, S., Kataoka, Y. and Takeichi, M (1996). Zygotic Drosophila E-cadherin expression is required for processes of dynamic epithelial cell rearrangement in the Drosophila embryo. Genes Dev. 10, 659-671.
37. Vinson, C. and Adler, P. N. (1987). Directional non-cell autonomy and the transmission of polarity information by the frizzled gene of Drosophila. Nature 329, 549-551
38. van de Wetering, M., Cavallo, R., Doijes, D., von Beest, M., von Es, J., Loureiro, J., Ypama, A., Hursh, D., Jones, T., Bejsovec, A., Peifer, M., Mortin, M. and Clever, H. (1997). Armadillo coactivates transcription dirven by the product to the Drosophila segment polarity gene TCF. Cell 88, 789-799.
39. Wong, L. L. and Adler, P. N. (1993). Tissue polarity genes of Drosophila regulate the subcellular location for prehair initiation in pupal wing cell. J. Cell Biol. 123, 209-221.
40. Xu, T. and Rubin, G. M. (1993). Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 117, 1223-1237
41. Zheng, L., Zhang, J. and Carthew, R. (1995). frizzled regulates mirror-symmetric pattern formation in the Drosophila eye. Development, 121, 3045-3055.