A role for Xrcc2 in the early stages of mouse development

DNA Repair

Volumn 6, Issue 2, 2007, Pages 224-234

  Adam, Julie ^a   Deans, Bryan ^a   Thacker, John ^a  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

Apoptosis; Atm; Homologous recombination; Neurogenesis; p53; Somitogenesis; Xrcc2

Indexed keywords

ATM PROTEIN; MARKER; ONCOPROTEIN; PROTEIN DERIVATIVE; PROTEIN P53; TRANSCRIPTION FACTOR DELTA LIKE 1; TRYPTOPHAN; UNCLASSIFIED DRUG; XRCC2 PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL LOSS; DEVELOPMENTAL STAGE; EMBRYO; EMBRYONAL TISSUE; FIBROBLAST CULTURE; HOMOLOGOUS RECOMBINATION; KNOCKOUT MOUSE; LETHALITY; MORPHOLOGY; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN DEPLETION; SOMITE; SOMITOGENESIS; SURVIVAL;

ANIMALS; APOPTOSIS; BASE SEQUENCE; CELL CYCLE PROTEINS; DNA DAMAGE; DNA PRIMERS; DNA REPAIR; DNA-BINDING PROTEINS; EMBRYONIC DEVELOPMENT; FEMALE; GENES, P53; GESTATIONAL AGE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVOUS SYSTEM; PHENOTYPE; PREGNANCY; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA; MAMMALIA; MUS;

EID: 33846108636     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2006.10.024     Document Type: Article

References (45)

1. Sonoda E., Sasaki M.S., Buerstedde J.M., Bezzubova O., Shinohara A., Ogawa H., Takata M., Yamaguchi-Iwai Y., and Takeda S. Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death. EMBO J. 17 (1998) 598-608
2. Cui X., Brenneman M., Meyne J., Oshimura M., Goodwin E.H., and Chen D.J. The XRCC2 and XRCC3 repair genes are required for chromosome stability in mammalian cells. Mutat. Res. 434 (1999) 75-88
3. Griffin C.S., Simpson P.J., Wilson C.R., and Thacker J. Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation. Nat. Cell Biol. 2 (2000) 757-761
4. Takata M., Sasaki M.S., Tachiiri S., Fukushima T., Sonoda E., Schild D., Thompson L.H., and Takeda S. Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs. Mol. Cell Biol. 21 (2001) 2858-2866
5. Deans B., Griffin C.S., O'Regan P., Jasin M., and Thacker J. Homologous recombination deficiency leads to profound genetic instability in cells derived from Xrcc2-knockout mice. Cancer Res. 63 (2003) 8181-8187
6. Smiraldo P.G., Gruver A.M., Osborn J.C., and Pittman D.L. Extensive chromosomal instability in Rad51d-deficient mouse cells. Cancer Res. 65 (2005) 2089-2096
7. Thacker J. A surfeit of RAD51-like genes?. Trends Genet. 15 (1999) 166-168
8. Masson J.Y., Tarsounas M.C., Stasiak A.Z., Stasiak A., Shah R., McIlwraith M.J., Benson F.E., and West S.C. Identification and purification of two distinct complexes containing the five RAD51 paralogs. Genes Dev. 15 (2001) 3296-3307
9. Miller K.A., Yoshikawa D.M., McConnell I.R., Clark R., Schild D., and Albala J.S. RAD51C interacts with RAD51B and is central to a larger protein complex in vivo exclusive of RAD51. J. Biol. Chem. 277 (2002) 8406-8411
10. French C.A., Masson J.Y., Griffin C.S., O'Regan P., West S.C., and Thacker J. Role of mammalian RAD51L2 (RAD51C) in recombination and genetic stability. J. Biol. Chem. 277 (2002) 19322-19330
11. Liu Y., Masson J.Y., Shah R., O'Regan P., and West S.C. RAD51C is required for Holliday junction processing in mammalian cells. Science 303 (2004) 243-246
12. Deans B., Griffin C.S., Maconochie M., and Thacker J. Xrcc2 is required for genetic stability, embryonic neurogenesis and viability in mice. EMBO J. 19 (2000) 6675-6685
13. Meek D.W. The p53 response to DNA damage. DNA Repair (Amst.) 3 (2004) 1049-1056
14. Shiloh Y. ATM and ATR: networking cellular responses to DNA damage. Curr. Opin. Genet. Dev. 11 (2001) 71-77
15. Allen D.M., van Praag H., Ray J., Weaver Z., Winrow C.J., Carter T.A., Braquet R., Harrington E., Ried T., Brown K.D., Gage F.H., and Barlow C. Ataxia telangiectasia mutated is essential during adult neurogenesis. Genes Dev. 15 (2001) 554-566
16. Morrison C., Sonoda E., Takao N., Shinohara A., Yamamoto K., and Takeda S. The controlling role of ATM in homologous recombinational repair of DNA damage. EMBO J. 19 (2000) 463-471
17. Donehower L.A., Harvey M., Slagle B.L., McArthur M.J., Montgomery Jr. C.A., Butel J.S., and Bradley A. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356 (1992) 215-221
18. Elson A., Wang Y., Daugherty C.J., Morton C.C., Zhou F., Campos-Torres J., and Leder P. Pleiotropic defects in ataxia-telangiectasia protein-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 13084-13089
19. Todaro G.J., and Green H. Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J. Cell Biol. 17 (1963) 299-313
20. Kaufman M.H. The Atlas of Mouse Development (1992), Academic Press, London
21. Theiler K. The House Mouse Altas of Embryonic Development (1989), Springer-Verlag, New York
22. Krajewska M., Wang H.G., Krajewski S., Zapata J.M., Shabaik A., Gascoyne R., and Reed J.C. Immunohistochemical analysis of in vivo patterns of expression of CPP32 (Caspase-3), a cell death protease. Cancer Res. 57 (1997) 1605-1613
23. Wilkinson D.G. Whole Mount In Situ Hybridisation of Vertebrate Embryos, In Situ Hybridisation (1992), IRL Press, Oxford pp. 75-83
24. Henrique D., Adam J., Myat A., Chitnis A., Lewis J., and Ish-Horowicz D. Expression of a Delta homologue in prospective neurons in the chick. Nature 375 (1995) 787-790
25. Kaufman M., and Bard J. The Anatomical Basis of Mouse Development (1999), Academic Press, Edinburgh, UK
26. Frank K.M., Sharpless N.E., Gao Y., Sekiguchi J.M., Ferguson D.O., Zhu C., Manis J.P., Horner J., DePinho R.A., and Alt F.W. DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway. Mol. Cell 5 (2000) 993-1002
27. Gao Y., Ferguson D.O., Xie W., Manis J.P., Sekiguchi J., Frank K.M., Chaudhuri J., Horner J., DePinho R.A., and Alt F.W. Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development. Nature 404 (2000) 897-900
28. Louvi A., and Artavanis-Tsakonas S. Notch signalling in vertebrate neural development. Nat. Rev. Neurosci. 7 (2006) 93-102
29. Bettenhausen B., Hrabe de Angelis M., Simon D., Guenet J.L., and Gossler A. Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta. Development 121 (1995) 2407-2418
30. Artus J., Babinet C., and Cohen-Tannoudji M. The cell cycle of early mammalian embryos: lessons from genetic mouse models. Cell Cycle 5 (2006) 499-502
31. Kozar K., Ciemerych M.A., Rebel V.I., Shigematsu H., Zagozdzon A., Sicinska E., Geng Y., Yu Q., Bhattacharya S., Bronson R.T., Akashi K., and Sicinski P. Mouse development and cell proliferation in the absence of d-cyclins. Cell 118 (2004) 477-491
32. Heyer B.S., MacAuley A., Behrendtsen O., and Werb Z. Hypersensitivity to DNA damage leads to increased apoptosis during early mouse development. Genes Dev. 14 (2000) 2072-2084
33. Campos L.S., Duarte A.J., Branco T., and Henrique D. mDll1 and mDll3 expression in the developing mouse brain: role in the establishment of the early cortex. J. Neurosci. Res. 64 (2001) 590-598
34. Hrabe de Angelis M., McIntyre II J., and Gossler A. Maintenance of somite borders in mice requires the Delta homologue DII1. Nature 386 (1997) 717-721
35. Dubrulle J., and Pourquie O. Coupling segmentation to axis formation. Development 131 (2004) 5783-5793
36. Barnes D.E., Stamp G., Rosewell I., Denzel A., and Lindahl T. Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice. Curr. Biol. 8 (1998) 1395-1398
37. Frank K.M., Sekiguchi J.M., Seidl K.J., Swat W., Rathbun G.A., Cheng H.L., Davidson L., Kangaloo L., and Alt F.W. Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV. Nature 396 (1998) 173-177
38. Gao Y., Sun Y., Frank K.M., Dikkes P., Fujiwara Y., Seidl K.J., Sekiguchi J.M., Rathbun G.A., Swat W., Wang J., Bronson R.T., Malynn B.A., Bryans M., Zhu C., Chaudhuri J., Davidson L., Ferrini R., Stamato T., Orkin S.H., Greenberg M.E., and Alt F.W. A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis. Cell 95 (1998) 891-902
39. Lee Y., Barnes D.E., Lindahl T., and McKinnon P.J. Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm. Genes Dev. 14 (2000) 2576-2580
40. Sekiguchi J., Ferguson D.O., Chen H.T., Yang E.M., Earle J., Frank K., Whitlow S., Gu Y., Xu Y., Nussenzweig A., and Alt F.W. Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 3243-3248
41. Sugo N., Niimi N., Aratani Y., Takiguchi-Hayashi K., and Koyama H. p53 deficiency rescues neuronal apoptosis but not differentiation in DNA polymerase beta-deficient mice. Mol. Cell Biol. 24 (2004) 9470-9477
42. McAllister K.A., and Wiseman R.W. Are Trp53 rescue of Brca1 embryonic lethality and Trp53/Brca1 breast cancer association related?. Breast Cancer Res. 4 (2002) 54-57
43. Henry-Mowatt J., Jackson D., Masson J.Y., Johnson P.A., Clements P.M., Benson F.E., Thompson L.H., Takeda S., West S.C., and Caldecott K.W. XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes. Mol. Cell 11 (2003) 1109-1117
44. Shechter D., Costanzo V., and Gautier J. Regulation of DNA replication by ATR: signaling in response to DNA intermediates. DNA Repair (Amst.) 3 (2004) 901-908
45. Del Rio J.A., Martinez A., Auladell C., and Soriano E. Developmental history of the subplate and developing white matter in the murine neocortex. Neuronal organization and relationship with the main afferent systems at embryonic and perinatal stages. Cereb. Cortex 10 (2000) 784-801