Coupling segmentation to axis formation

Development

Volumn 131, Issue 23, 2004, Pages 5783-5793

  Dubrulle, Julien ^a,b   Pourquié, Olivier ^a  

^a STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AXIN; FIBROBLAST GROWTH FACTOR; MORPHOGEN; RETINOIC ACID; T CELL FACTOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXC1; TRANSCRIPTION FACTOR FOXC2; UNCLASSIFIED DRUG; WNT PROTEIN;

ANTERIOR POSTERIOR AXIS; BONE DEVELOPMENT; EMBRYO DEVELOPMENT; EMBRYO PATTERN FORMATION; MESODERM; MORPHOGENESIS; MOUSE; MUSCLE DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; REVIEW; SOMITE; SPINE; SYSTEMATIC REVIEW; VERTEBRATE;

ANIMALS; BODY PATTERNING; CHICK EMBRYO; EMBRYO; EMBRYONIC DEVELOPMENT; HUMANS; IN SITU HYBRIDIZATION; MESODERM; MICE; SIGNAL TRANSDUCTION; SOMITES; TRETINOIN;

VERTEBRATA;

EID: 12344286205     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.01519     Document Type: Review

References (128)

1. Abu-Abed, S., Dolle, P., Metzger, D., Wood, C., MacLean, G., Chambon, P. and Petkovich, M. (2003). Developing with lethal RA levels: genetic ablation of Rarg can restore the viability of mice lacking Cyp26a1. Development 130. 1449-1459.
2. Aerne, B. and Ish-Horowicz, D. (2004). Receptor tyrosine phosphatase psi is required for Delta/Notch signalling and cyclic gene expression in the presomitic mesoderm. Development 131, 3391-3399.
3. Aulehla, A. and Herrmann, B. G. (2004). Segmentation in vertebrates: clock and gradient finally joined. Genes Dev. 18 2060-2067.
4. Aulehla, A., Wehrle, C., Brand-Saberi, B., Kemler, R., Gossler, A., Kanzler, B. and Herrmann, B. G. (2003). Wnt3a plays a major role in the segmentation clock controlling somitogenesis. Dev. Cell 4, 395-406.
5. Bagnall, K. M., Higgins, S. J. and Sanders, E. J. (1988). The contribution made by a single somite to the vertebral column: experimental evidence in support of resegmentation using the chick-quail chimaera model. Development 103, 69-85.
6. Barrantes, I. B., Elia, A. J., Wunsch, K., Hrabe de Angelis, M. H., Mak, T. W., Rossant, J., Conlon, R. A., Gossler, A. and de la Pompa, J. L. (1999). Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse. Curr. Biol. 9, 470-480.
7. Barrios, A., Poole, R.J., Durbin, L., Brennan, C., Holder, N. and Wilson, S. W. (2003). Eph/Ephrin signaling regulates the mesenchymal-to-epithelial transition of the paraxial mesoderm during somite morphogenesis. Curr. Biol. 13, 1571-1582.
8. Bellairs, R. (1986). The primitive streak. Anat. Embryol. 174, 1-14.
9. Bessho, Y., Hirata, H., Masamizu, Y. and Kageyama, R. (2003). Periodic repression by the bHLH factor Hes7 is an essential mechanism for the somite segmentation clock. Genes Dev. 17, 1451-1456.
10. Blentic, A., Gale, E. and Maden, M. (2003). Retinoic acid signalling centres in the avian embryo identified by sites of expression of synthesising and catabolising enzymes. Dev. Dyn. 227, 114-127.
11. Brent, A. E. and Tabin, C. J. (2002). Developmental regulation of somite derivatives: muscle, cartilage and tendon. Curr. Opin. Genet. Dev. 12, 548-557.
12. Brent, A. E., Schweitzer, R. and Tabin, C. J. (2003). A somitic compartment of tendon progenitors. Cell 113, 235-248.
13. Bronner-Fraser, M. (2000). Rostrocaudal differences within the somites confer segmental pattern to trunk neural crest migration. Curr. Top. Dev. Biol. 47, 279-296.
14. Buchberger, A., Seidl, K., Klein, C., Eberhardt, H. and Arnold, H. H. (1998). cMeso-1, a novel bHLH transcription factor, is involved in somite formation in chicken embryos. Dev. Biol. 199 201-215.
15. Burgess, R., Cserjesi, P., Ligon, K. L. and Olson, E. N. (1995). Paraxis: a basic helix-loop-helix protein expressed in paraxial mesoderm and developing somites. Dev. Biol. 168, 296-306.
16. Burgess, R., Rawls, A., Brown, D., Bradley, A. and Olson, E. N. (1996). Requirement of the paraxis gene for somite formation and musculoskeletal patterning. Nature 384, 570-573.
17. Cambray, N. and Wilson, V. (2002). Axial progenitors with extensive potency are localised to the mouse chordoneural hinge. Development 129, 4855-4866.
18. Catala, M.,Teillet, M. A. and le Douarin, N. M. (1995). Organization and development of the tail bud analyzed with the quail-chick chimaera system. Mech. Dev. 51, 51-65.
19. Chapman, D. L., Agulnik, I., Hancock, S., Silver, L. M. and Papaioannou, V. E. (1996). Tbx6, a mouse T-Box gene implicated in paraxial mesoderm formation at gastrulation. Dev. Biol. 180, 534-542.
20. Christ, B., Schmidt, C., Huang, R., Wilting, J. and Brand-Saberi, B. (1998). Segmentation of the vertebrate body. Anat. Embryol. 197, 1-8.
21. Cinquin, O. (2003). Is the somitogenesis clock really cell-autonomous? A coupled-oscillator model of segmentation. J. Theor. Biol. 224, 459-468.
22. Ciruna, B. and Rossant, J. (2001). FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak. Dev. Cell 1, 37-49.
23. Cole, S. E., Levorse, J. M., Tilghman, S. M. and Vogt, T. F. (2002). Clock regulatory elements control cyclic expression of lunatic fringe during somitogenesis. Dev. Cell 3, 75-84.
24. Conlon, R. A. (1995). Retinoic acid and pattern formation in vertebrates. Trends Genet. 11, 314-319.
25. Conlon, R. A., Reaume, A. G. and Rossant, J. (1995). Notch1 is required for the coordinate segmentation of somites. Development 121, 1533-1545.
26. Cooke, J. and Zeeman, E. C. (1976). A clock and wavefront model for control of the number of repeated structures during animal morphogenesis. J. Theor. Biol. 58, 455-476.
27. Cordes, R., Schuster-Gossler, K., Serth, K. and Gossler, A. (2004). Specification of vertebral identity is coupled to Notch signalling and the segmentation clock. Development 131, 1221-1233.
28. Dale, J. K. and Pourquie, O. (2000). A clock-work somite. Bioessavs 22, 72-83.
29. Dale, J. K., Maroto, M., Dequeant, M. L., Malapert, P., McGrew, M. and Pourquie, O. (2003). Periodic Notch inhibition by Lunatic Fringe underlies the chick segmentation clock. Nature 421, 275-278.
30. Diez del Corral, R., Olivera-Martinez, I., Goriely, A., Gale, E., Maden, M. and Storey, K. (2003). Opposing FGF and retinoid pathways control ventral neural pattern, neuronal differentiation, and segmentation during body axis extension. Neuron 40, 65-79.
31. Duband, J. L., Dufour, S., Hatta, K., Takeichi, M., Edelman, G. M. and Thiery, J. P. (1987). Adhesion molecules during somitogenesis in the avian embryo. J. Cell Biol. 104, 1361-1374.
32. Dubrulle, J. and Pourquie, O. (2004). fgf8 mRNA decay establishes a gradient that couples axial elongation to patterning in the vertebrate embryo. Nature 427, 419-422.
33. Dubrulle, J., McGrew, M. J. and Pourquie, O. (2001). FGF signaling controls somite boundary position and regulates segmentation clock control of spatiotemporal Hox gene activation. Cell 106, 219-232.
34. Durbin, L., Brennan, C., Shiomi, K., Cooke, J., Barrios, A., Shanmugalingam, S., Guthrie, B., Lindberg, R. and Holder, N. (1998). Eph signaling is required for segmentation and differentiation of the somites. Genes Dev. 12, 3096-3109.
35. Eloy-Trinquet, S. and Nicolas, J. F. (2002). Clonal separation and regionalisation during formation of the medial and lateral myotomes in the mouse embryo. Development 129, 111-122.
36. Fleming, A., Keynes, R. and Tannahill, D. (2004). A central role for the notochord in vertebral patterning. Development 131, 873-880.
37. Freitas, C., Rodrigues, S., Charrier, J. B., Teillet, M. A. and Palmeirim, I. (2001). Evidence for medial/lateral specification and positional information within the presomitic mesoderm. Development 128, 5139-5147.
38. Freund, R., Dorfler, D., Popp, W. and Wachtler, F. (1996). The metameric pattern of the head mesoderm - does it exist? Anat. Embryol. 193, 73-80.
39. -/- mice. Genes Dev. 13, 709-717.
40. Galceran, J., Sustmann, C., Hsu, S.-C., Folberth, S. and Grosschedl, R. (2004). LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis. Genes Dev. (in press).
41. Garcia-Martinez, V. and Schoenwolf, G. C. (1992). Positional control of mesoderm movement and fate during avian gastrulation and neurulation. Dev. Dyn. 193, 249-256.
42. Gardner, R. L. and Beddington, R. S. (1988). Multi-lineage 'stem' cells in the mammalian embryo. J. Cell Sci. 10, 11-27.
43. Gont, L. K., Steinbeisser, H., Blumberg, B. and de Robertis, E. M. (1993). Tail formation as a continuation of gastrulation: the multiple cell populations of the Xenopus tailbud derive from the late blastopore lip. Development 119, 991-1004.
44. Greco, T. L., Takada, S., Newhouse, M. M., McMahon, J. A., Mcmahon, A. P. and Camper, S. A. (1996). Analysis of the vestigial tail mutation demonstrates that Wnt-3a gene dosage regulates mouse axial development. Genes Dev. 10, 313-324.
45. Griffin, K. J. and Kimelman, D. (2002). One-Eyed Pinhead and Spadetail are essential for heart and somite formation. Nat. Cell Biol. 4, 821-825.
46. Hamilton, L. (1969). The formation of somites in Xenopus. J. Embryol. Exp. Morphol. 22, 253-264.
47. Helmbacher, F., Schneider-Maunoury, S., Topilko, P., Tiret, L. and Charnay, P. (2000). Targeting of the EphA4 tyrosine kinase receptor affects dorsal/ventral pathfinding of limb motor axons. Development 127, 3313-3324.
48. Henry, C. A., Hall, L. A., Burr Hille, M., Solnica-Krezel, L. and Cooper, M. S. (2000). Somites in zebrafish doubly mutant for knypek and trilobite form without internal mesenchymal cells or compaction. Curr. Biol. 10, 1063-1066.
49. Herrmann, B. G., Labeit, S., Poustka, A., King, T. R. and Lehrach, H. (1990). Cloning of the T gene required in mesoderm formation in the mouse. Nature 343, 617-622.
50. Hinsch, C. W. and Hamilton, H. L. (1956). The developmental fate of the first somite in the chick embryo. Anat. Rec. 125, 225-246.
51. Hirata, H., Bessho, Y., Kokubu, H., Masamizu, Y., Yamada, S., Lewis, J. and Kageyama, R. (2004). Instability of Hes7 protein is crucial for the somite segmentation clock. Nat. Genet. 36, 750-754.
52. Hofmann, M., Schuster-Gossler, Watabe-Rudolph, M., Aulehla, A., Herrmann, B. G. and Gossler, A. (2004). WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating DI11 expression in the presomitic mesoderm of mouse embryos. Genes Dev. (in press).
53. Horikawa, K., Radice, G., Takeichi, M. and Chisaka, O. (1999). Adhesive subdivisions intrinsic to the epithelial somites. Dev. Biol. 215, 182-189.
54. Huang, R., Zhi, Q., Ordahl, C. P. and Christ, B. (1997). The fate of the first avian somite. Anat. Embryol. 195 435-449.
55. Jen, W. C., Gawantka, V., Pollet, N., Niehrs, C. and Kintner, C. (1999). Periodic repression of Notch pathway genes governs the segmentation of Xenopus embryos. Genes Dev. 13, 1486-1499.
56. Johnson, J., Rhee, J., Parsons, S. M., Brown, D., Olson, E. N. and Rawls, A. (2001). The anterior/posterior polarity of somites is disrupted in paraxis-deficient mice. Dev. Biol. 229, 176-187.
57. Jouve, C., Iimura, T. and Pourquie, O. (2002). Onset of the segmentation clock in the chick embryo: evidence for oscillations in the somite precursors in the primitive streak. Development 129 1107-1117.
58. Kanki, J. P. and Ho, R. K. (1997). The development of the posterior body in zebrafish. Development 124, 881-893.
59. Kieny, M., Mauger, A. and Sengel, P. (1972). Early regionalization of somitic mesoderm as studied by the development of axial skeleton of the chick embryo. Dev. Biol. 28, 142-161.
60. Kim, S. H., Jen, W. C., de Robertis, E. M. and Kintner, C. (2000). The protocadherin PAPC establishes segmental boundaries during somitogenesis in xenopus embryos. Curr. Biol. 10, 821-830.
61. Kimura, Y., Matsunami, H., Inoue, T., Shimamura, K., Uchida, N., Ueno, T., Miyazaki, T. and Takeichi, M. (1995). Cadherin-11 expressed in association with mesenchymal morphogenesis in the head, somite, and limb bud of early mouse embryos. Dev. Biol. 169, 347-358.
62. Knezevic, V., de Santo, R. and Mackem, S. (1998). Continuing organizer function during chick tail development. Development 125, 1791-1801.
63. Krumlauf, R. (1994). Hox genes in vertebrate development. Cell 78, 191-201.
64. Kulesa, P. M. and Fraser, S. E. (2002). Cell dynamics during somite boundary formation revealed by time-lapse analysis. Science 298, 991-995.
65. Kume, T., Jiang, H., Topczewska, J. M. and Hogan, B. L. (2001). The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis. Genes Dev. 15, 2470-2482.
66. Kuratani, S., Horigome, N. and Hirano, S. (1999). Developmental morphology of the head mesoderm and reevaluation of segmental theories of the vertebrate head: evidence from embryos of an agnathan vertebrate, Lampetra japonica. Dev. Biol. 210, 381-400.
67. Lawrence, P. A. (1992). The Making of a Fly. Oxford, UK: Blackwell Science.
68. Lewis, J. (2003). Autoinhibition with transcriptional delay: a simple mechanism for the zebrafish somitogenesis oscillator. Curr. Biol. 13, 1398-1408.
69. Li, Y., Fenger, U., Niehrs, C. and Pollet, N. (2003). Cyclic expression of esr9 gene in Xenopus presomitic mesoderm. Differentiation 71, 83-89.
70. Linask, K. K., Ludwig, C., Han, M. D., Liu, X., Radice, G. L. and Knudsen, K. A. (1998). N-cadherin/catenin-mediated morphoregulation of somite formation. Dev. Biol. 202, 85-102.
71. Lohnes, D., Mark, M., Mendelsohn, C., Dolle, P., Dierich, A., Gorry, P., Gansmuller, A. and Chambon, P. (1994). Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants. Development 120 2723-2748.
72. Maden, M., Graham, A., Zile, M. and Gale, E. (2000). Abnormalities of somite development in the absence of retinoic acid. Int. J. Dev. Biol. 44, 151-159.
73. Marcelle, C., Lesbros, C. and Linker, C. (2002). Somite patterning: a few more pieces of the puzzle. Results Probl. Cell Differ. 38, 81-108.
74. Marlow, F., Gonzalez, E. M., Yin, C., Rojo, C. and Solnica-Krezel, L. (2004). No tail co-operates with non-canonical Wnt signaling to regulate posterior body morphogenesis in zebrafish. Development 131, 203-216.
75. McMahon, J. A., Takada, S., Zimmerman, L. B., Fan, C. M., Harland, R. M. and McMahon, A. P. (1998). Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite. Genes Dev. 12, 1438-1452.
76. Meinhardt, H. (1986). Models of segmentation. In Somites in Developing Embryos (ed. R. Bellairs, D. A. Ede and J. W. Lash), pp. 179-191. London, UK: Plenum Press.
77. Mellitzer, G., Xu, Q. and Wilkinson, D. G. (1999). Eph receptors and ephrins restrict cell intermingling and communication. Nature 400, 77-81.
78. Minguillon, C. and Garcia-Fernandez, J. (2002). The single amphioxus Mox gene: insights into the functional evolution of Mox genes, somites, and the asymmetry of amphioxus somitogenesis. Dev. Biol. 246, 455-465.
79. Morales, A. V., Yasuda, Y. and Ish-Horowicz, D. (2002). Periodic lunatic fringe expression is controlled during segmentation by a cyclic transcriptional enhancer responsive to Notch signaling. Dev. Cell 3, 63-74.
80. Moreno, T. A. and Kintner, C. (2004). Regulation of segmental patterning by retinoic acid signaling during Xenopus somitogenesis. Dev. Cell 6, 205-218.
81. Murai, K. K. and Pasquale, E. B. (2003). 'Eph'ective signaling: forward, reverse and crosstalk. J. Cell Sci. 116, 2823-2832.
82. Nakaya, Y., Kuroda, S., Katagiri, Y. T., Kaibuchi, K. and Takahashi, Y. (2004). Mesenchymal-epithelial transition during somitic segmentation is regulated by differential roles of Cdc42 and Rac1. Dev. Cell 7, 425-438.
83. Nicolas, J. F., Mathis, L., Bonnerot, C. and Saurin, W. (1996). Evidence in the mouse for self-renewing stem cells in the formation of a segmented longitudinal structure, the myotome. Development 122, 2933-2946.
84. Niederreither, K., Subbarayan, V., Dolle, P. and Chambon, P. (1999). Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nat. Genet. 21. 444-448.
85. Niederreither, K., Vermot, J., le Roux, I., Schuhbaur, B., Chambon, P. and Dolle, P. (2003). The regional pattern of retinoic acid synthesis by RALDH2 is essential for the development of posterior pharyngeal arches and the enteric nervous system. Development 130, 2525-2534.
86. Nikaido, M., Kawakami, A., Sawada, A., Furutani-Seiki, M., Takeda, H. and Araki, K. (2002). Tbx24, encoding a T-box protein, is mutated in the zebrafish somite-segmentation mutant fused somites. Nat. Genet. 31, 195-199.
87. Nowicki, J. L. and Burke, A. C. (2000). Hex genes and morphological identity: axial versus lateral patterning in the vertebrate mesoderm. Development 127, 4265-4275.
88. Ordahl, C. P. and le Douarin, N. M. (1992). Two myogenic lineages within the developing somite. Development 114 339-353.
89. Packard, D. S. J. and Meier, S. (1983). An experimental study of the somitomeric organization of the avian segmental plate. Dev. Biol. 97, 191-202.
90. Palmeirim, I., Henrique, D., Ish-Horowicz, D. and Pourquié, O. (1997). Avian hairy gene expression identifies a molecular clock linked to vertebrate segmentation and somitogenesiss. Cell 91, 639-648.
91. Panin, V. M., Papayannopoulos, V., Wilson, R. and Irvine, K. D. (1997). Fringe modulates Notch-ligand interactions. Nature 387, 908-912.
92. Pourquie, O. (2003). The segmentation clock: converting embryonic time into spatial pattern. Science 301, 328-330.
93. Pourquie, O. and Tam, P. P. (2001). A nomenclature for prospective somites and phases of cyclic gene expression in the presomitic mesoderm. Dev. Cell 1, 619-620.
94. Primmett, D. R., Norris, W. E., Carlson, G. J., Keynes, R. J. and Stern, C. D. (1989). Periodic segmental anomalies induced by heat shock in the chick embryo are associated with the cell cycle. Development 105, 119-130.
95. Psychoyos, D. and Stern, C. D. (1996). Fates and migratory routes of primitive streak cells in the chick embryo. Development 122, 1523-1534.
96. Rhee, J., Takahashi, Y., Saga, Y., Wilson-Rawls, J. and Rawls, A. (2003). The protocadherin papc is involved in the organization of the epithelium along the segmental border during mouse somitogenesis. Dev. Biol. 254, 248-261.
97. Rida, P. C., le Minh, N. and Jiang, Y. J. (2004). A Notch feeling of somite segmentation and beyond. Dev. Biol. 265 2-22.
98. Saga, Y. and Takeda, H. (2001). The making of the somite: molecular events in vertebrate segmentation. Nat. Rev. Genet. 2, 835-845.
99. Saga, Y., Hata, N., Koseki, H. and Taketo, M. M. (1997). Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation. Genes Dev. 11, 1827-1839.
100. Sakai, Y., Meno, C., Fujii, H., Nishino, J., Shiratori, H., Saijoh, Y., Rossant, J. and Hamada, H. (2001). The retinoic acid-inactivating enzyme CYP26 is essential for establishing an uneven distribution of retinoic acid along the anterio-posterior axis within the mouse embryo. Genes Dev. 15, 213-225.
101. Sato, Y., Yasuda, K. and Takahashi, Y. (2002). Morphogical boundary forms by a novel inductive event mediated by Lunatic fringe and Notch during somitic segmentation. Development 129 3633-3644.
102. Sawada, A., Fritz, A., Jiang, Y., Yamamoto, A., Yamasu, K., Kuroiwa, A., Saga, Y. and Takeda, H. (2000). Zebrafish Mesp family genes, mesp-a and mesp-b are segmentally expressed in the presomitic mesoderm, and Mesp-b confers the anterior identity to the developing somites. Development 127, 1691-1702.
103. Sawada, A., Shinya, M., Jiang, Y. J., Kawakami, A., Kuroiwa, A. and Takeda, H. (2001). Fgf/MAPK signalling is a crucial positional cue in somite boundary formation. Development 128, 4873-4880.
104. Schoenwolf, G. C., Garcia-Martinez, V. and Dias, M. S. (1992). Mesoderm movement and fate during avian gastrulation and neurulation. Dev. Dyn. 193, 235-248.
105. Schubert, M., Holland, L. Z., Stokes, M. D. and Holland, N. D. (2001). Three amphioxus Wnt genes (AmphiWnt3, AmphiWnt5, and AmphiWnt6) associated with the tail bud: the evolution of somitogenesis in chordates. Dev. Biol. 240, 262-273.
106. Selleck, M. A. and Stern, C. D. (1991). Fate mapping and cell lineage analysis of Hensen's node in the chick embryo. Development 112, 615-626.
107. Serth, K., Schuster-Gossler, K., Cordes, R. and Gossler, A. (2003). Transcriptional oscillation of Lunatic fringe is essential for somitogenesis. Genes Dev. 17, 912-925.
108. Slack, J. M. (1991). From egg to embryo. Cambridge, UK: Cambridge University Press.
109. Sosic, D., Brand-Saberi, B., Schmidt, C., Christ, B. and Olson, E. N. (1997). Regulation of paraxis expression and somite formation by ectoderm- and neural tube-derived signals. Dev. Biol. 185, 229-243.
110. Sparrow, D. B., Jen, W. C., Kotecha, S., Towers, N., Kintner, C. and Mohun, T. J. (1998). Thylacine 1 is expressed segmentally within the paraxial mesoderm of the Xenopus embryo and interacts with the Notch pathway. Development 125, 2041-2051.
111. Stern, C. D. and Keynes, R. J. (1987). Interactions between somite cells: the formation and maintenance of segment boundaries in the chick embryo. Development 99, 261-272.
112. Stern, C. D., Artinger, K. B. and Bronner-Fraser, M. (1991). Tissue interactions affecting the migration and differentiation of neural crest cells in the chick embryo. Development 113, 207-216.
113. Stern, C. D., Hatada, Y., Selleck, M. A. and Storey, K. G. (1992). Relationships between mesoderm induction and the embryonic axes in chick and frog embryos. Development Suppl. 151-156.
114. Streit, A. and Stern, C. D. (1999). Mesoderm patterning and somite formation during node regression: differential effects of chordin and noggin. Mech. Dev. 85, 85-96.
115. Sun, X., Meyers, E. N., Lewandoski, M. and Martin, G. R. (1999). Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo. Genes Dev. 13, 1834-1846.
116. Takahashi, Y., Koizumi, K., Takagi, A., Kitajima, S., Inoue, T., Koseki, H. and Saga, Y. (2000). Mesp2 initiates somite segmentation through the Notch signalling pathway. Nat. Genet. 25, 390-396.
117. Tam, P. P. (1981). The control of somitogenesis in mouse embryos. J. Embryol. Exp. Morphol. 65 Suppl, 103-128.
118. Tam, P. P. (1988). The allocation of cells in the presomitic mesoderm during somite segmentation in the mouse embryo. Development 103, 379-390.
119. Tam, P. P. and Beddington, R. S. P. (1986). The metameric organization of the presomitic mesoderm and somite specification in the mouse embryo. In Somites in Developing Embryos (ed. R. Bellairs, D. A. Ede and J. W. Lash), pp. 17-36. London, UK: Plenum Press.
120. Tonegawa, A. and Takahashi, Y. (1998). Somitogenesis controlled by Noggin. Dev. Biol. 202, 172-182.
121. Topczewska, J. M., Topczewski, J., Shostak, A., Kume, T., Solnica-Krezel, L. and Hogan, B. L. (2001). The winged helix transcription factor Foxc1a is essential for somitogenesis in zebrafish. Genes Dev. 15, 2483-2493.
122. van Eeden, F. J., Granato, M., Schach, U., Brand, M., Furutani-Seiki, M., Haffter, P., Hammerschmidt, M., Heisenberg, C. P., Jiang, Y. J., Kane, D. A. et al. (1996). Mutations affecting somite formation and patterning in the zebrafish, Danio rerio. Development 123, 153-164.
123. Wang, H. U., Chen, Z. F. and Anderson, D. J. (1998). Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell 93, 741-753.
124. Yamaguchi T. P., Harpal, K., Henkemeyer, M. and Rossant, J. (1994). fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation. Genes Dev. 8, 3032-3044.
125. Yamaguchi, T. P., Bradley, A., McMahon, A. P. and Jones, S. (1999a). A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development 126, 1211-1223.
126. Yamaguchi, T. P., Takada, S., Yoshikawa, Y., Wu, N. and McMahon, A. P. (1999b). T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification. Genes Dev. 13, 3185-3190.
127. Yang, X., Dormann, D., Munsterberg, A. E. and Weijer, C. J. (2002). Cell movement patterns during gastrulation in the chick are controlled by positive and negative chemotaxis mediated by FGF4 and FGF8. Dev. Cell 3, 425-437.
128. Zakany, J., Kmita, M., Alarcon, P., de la Pompa, J. L. and Duboule, D. (2001). Localized and transient transcription of Hex genes suggests a link between patterning and the segmentation clock. Cell 106, 207-217.