Roundtrip ticket for secretory IgA: Role in mucosal homeostasis?

Journal of Immunology

Volumn 178, Issue 1, 2007, Pages 27-32

  Corthésy, Blaise ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

SECRETORY IMMUNOGLOBULIN;

ANTIBODY PRODUCTION; BREAST FEEDING; CELL ACTIVATION; CYTOKINE PRODUCTION; DENDRITIC CELL; GASTROINTESTINAL TRACT; HOMEOSTASIS; HOST RESISTANCE; HUMAN; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGLOBULIN PRODUCTION; LYMPHOID TISSUE; MUCOSAL IMMUNITY; NONHUMAN; PEYER PATCH; PRIORITY JOURNAL; SHORT SURVEY;

EID: 33845956481     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.1.27     Document Type: Short Survey

References (87)

1. Ogra, P. L., J. Mestecky, M. E. Lamm, W. Strober, J. Bienenstock, and J. R. McGhee. 1999. Mucosal Immunology, 2nd Ed., Academic Press, San Diego.
2. Strober, W., B. Kelsall, I. Fuss, T. March, B. Ludviksson, R. Ehrhardt, and M. Neurath, 1997. Reciprocal IFN-γ and TGF-β responses regulate the occurrence of mucosal inflammation. Immunol. Today 18: 61-64.
3. Makala, L. H., N. Suzuki, and H. Nagasawa, 2002. Peyer's patches: organized lymphoid structures for the induction of mucosal immune responses in the intestine. Pathobiology 70: 55-68.
4. Peyer, J. C. 1677. Exercitatio ant. De glandulis intestinarum earumque usu et affectionibus. In An Introduction to the History of Medicine, 4th Ed., F. H. Garrison, ed. Saunders, Philadelphia, p. 264.
5. Cornes, J. S. 1965. Peyer's patches in the human gut. Proc. R. Soc. Med. 58: 716.
6. Hamada, H., T. Hiroi, Y. Nishiyama, H. Takahashi, Y. Masunaga, S. Hachimura, S. Kaminogawa, H. Takahashi-Iwanaga, T. Iwanaga, H. Kiyono, et al. 2002. Identification of multiple isolated lymphoid follicles on the antimesenteric wall of the mouse small intestine. J. Immunol. 168: 57-64.
7. + lympho-hemopoietic progenitors develop. J. Exp. Med. 184: 1449-1459.
8. Moghaddami, M., A. Cummins, and G. Mayrhofer. 1998, Lymphocyte-filled villi: comparison with other lymphoid aggregations in the mucosa of the human small intestine. Gastroenterology 115: 1414-1425.
9. McWilliams, M., J. M. Phillips-Quagliata, and M. E. Lamm. 1977. Mesenteric lymph node B lymphoblasts which home to the small intestine are precommitted to IgA synthesis. J. Exp. Med. 145: 866-875.
10. Brandtzaeg, P., and R. Pabst. 2004. Let's go mucosal: communication on slippery ground. Trends Immunol. 25: 570-507.
11. Rescigno, M., M. Urbano, B. Valzasina, M. Francolini, G. Rotta, R. Bonasio, F. Granucci, J. P. Kraehenbuhl, and P. Ricciardi-Castagnoli, 2001. Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria. Nat. Immunol. 2: 361-367.
12. Neal, M. D., C. Leaphart, R. Levy, J. Prince, T. R. Billiar, S. Watkins, J. Li, S. Cetin, H. Ford, A. Schreiber, and D. J. Hackam. 2006. Enterocyte TLR4 mediates phagocytosis and translocation of bacteria across the intestinal barrier. J. Immunol. 176: 3070-3079.
13. Owen, R. L. 1999. Uptake and transport of intestinal macro molecules and microorganisms by M cells in Peyer's patches-a personal and historical perspective. Semin. Immunol. 11: 157-163.
14. Neutra, M. R., A. Frey, and J. P. Kraehenbuhl. 1996. Epithelial M cells: gateways for mucosal infection and immunization. Cell 86: 345-348.
15. Cuvelier, C. A., J. Quatacker, H. Mielants, M. De Vos, E. Veys, and H. J. Roels. 1994. M cells are damaged and increased in number in inflamed human ileal mucosa. Histopathology 24: 417-426.
16. Torres-Molina, A. 1981. Morphologic characteristics of the epithelial surface of aggregated lymphoid follicles (Peyer's patches) in the small intestine of newborn gnotobiotic calves and pigs. Am. J. Vet. Res. 42: 232-236.
17. Landsverk, T. 1987. The follicle-associated epithelium of the ileal Peyer's patch in ruminants is distinguished by its shedding of 50 nm particles. Immunol. Cell Biol. 65: 251-261.
18. El Bahi, S., E. Caliot, M. Bens, A. Bogdanova, S. Kerneis, A. Kahn, A. Vandewalle, and E. Pringault. 2002. Lymphoepithelial interactions trigger specific regulation of gene expression in the M cell-containing follicle-associated epithelium of Peyer's patches. J. Immunol. 168: 3713-3120.
19. Jang, M. H., M. N. Kweon, K. Iwatani, M. Yamamoto, K. Terahara, C. Sasakawa, T. Suzuki, T. Nochi, Y. Yokota, P. D. Rennert, et al. 2004. Intestinal villous M cells: an antigen entry site in the mucosal epithelium. Proc. Natl. Acad. Sci. USA 101: 6110-6115.
20. Hase, K., S. Ohshima, K. Kawano, N. Hashimoto, K. Matsumoto, H. Saito, and H. Ohno. 2005. Distinct gene expression profiles characterize cellular phenotypes of follicle-associated epithelium and M cells. DNA Res. 2: 127-137.
21. Pulendran, B., J. Banchereau, E. Maraskovsky, and C. Maliszewski. 2001. Modulating the immune response with dendritic cells and their growth factors. Trends Immunol. 22: 41-47.
22. Bilsborough, J., and J. L. Viney. 2004. Gastrointestinal dendritic cells play a role in immunity, tolerance, and disease. Gastroenterology 127: 300-309.
23. + T cells. J. Immunol. 164: 2890-2896.
24. Viney, J. L., A. M. Mowat, J. M. O'Malley, E. Williamson, and N. A. Fanger. 1998. Expanding dendritic cells in vivo enhances the induction of otal tolerance. J. Immunol. 160: 5815-5825.
25. Alpan, O., G. Rudomen, and P. Matzinger. 2001. The role of dendritic cells, B cells, and M cells in gut-oriented immune responses. J. Immunol. 166: 4843-4852.
26. Akbari, O., R. H. DeKruyff, and D. T. Umetsu. 2001. Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen. Nat. Immunol. 2: 725-731.
27. Williamson, E., J. M. Bilsborough, and J. L. Viney. 2002. Regulation of mucosal dendritic cell function by receptor activator of NF-κB (RANK)/RANK ligand interactions: impact on tolerance induction. J. Immunol. 169: 3606-3612.
28. Iwasaki, A., and B. L. Kelsall. 1999. Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin-10 and induce the differentiation of T helper type 2 cells. J. Exp. Med. 190: 229-239.
29. Huang, F. P., N. Platt, M. Wykes, J. R. Major, T. J. Powell, C. D. Jenkins, and G. G. MacPherson. 2000. A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes. J. Exp. Med. 191: 435-444.
30. Jang, M. H., N. Sougawa, T. Tanaka, T. Hirata, T. Hiroi, K. Tohya, Z. Guo, E. Umemoto, Y. Ebisuno, B. G. Yang, et al. 2006. CCR7 is critically important for migration of dendritic cells in intestinal lamina propria to mesenteric lymph nodes. J. Immunol. 176:803-810.
31. Worbs, T., U. Bode, S. Yan, M. W. Hoffmann, G. Hintzen, G. Bernhardt, R. Forster, and O. Pabst. 2006. Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells. J. Exp. Med. 203: 519-527.
32. 7 integrin. Eur. J. Immunol. 32: 1445-1454.
33. Mora, J. R., M. R. Bono, N. Manjunath, W. Weninger, L. L. Cavanagh, M. Rosemblatt, and U. H. Von Andrian. 2003. Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells. Nature 424: 88-93.
34. Brandtzaeg, P., E. S. Baekkevold, I. N. Farstad, F. L. Jahnsen, F. E. Johansen, E. M. Nilsen, and T. Yamanaka. 1999. Regional specialization in the mucosal immune system: what happens in the microcompartments. Immunol. Today 20: 141-151.
35. Parrott, D. M. 1976. The gut as a lymphoid organ. Clin. Gastroenterol. 5: 211-228.
36. Fagarasan, S., K. Kinoshita, M. Muramatsu, K. Ikuta, and T. Honjo. 2001. In situ class switching and differentiation to IgA-producing cells in the gut lamina propria. Nature 413: 639-643.
37. Brandtzaeg, P., and F. E. Johansen. 2005. Mucosal B cells: phenotypic characteristics, transcriptional regulation, and homing properties. Immunol. Rev. 206: 32-63.
38. Nagler-Anderson, C. 2001. Man the barrier! Strategic defences in the intestinal mucosa. Nat. Rev. Immunol. 1: 59-67.
39. Robinson, J. K., T. G. Blanchard, A. D. Levine, S. N. Emancipator, and M. E. Lamm. 2001. A mucosal IgA-mediated excretory immune system in vivo. J. Immunol. 166: 3688-3692.
40. Fujioka, H., S. N. Emancipator, M. Aikawa, D. S. Huang, F. Blatnik, T. Karban, K. DeFife, and M. B. Mazanec. 1998. Immunocytochemical colocalization of specific immunoglobulin A with Sendai virus protein in infected polarized epithelium. J. Exp. Med. 188: 1223-1229.
41. Fernandez, M. I., T. Pedron, R. Tournebize, J. C. Olivo-Marin, P. J. Sansonetti, and A. Phalipon. 2003. Anti-inflammatory role for intracellular dimeric immunoglobulin A by neutralization of lipopolysaccharide in epithelial cells. Immunity 18: 739-749.
42. Russell, M. W., D. A. Sibley, E. B. Nikolova, M. Tomana, and J. Mestecky. 1997. IgA antibody as a non-inflammatory regulator of immunity. Biochem. Soc. Trans. 25: 466-470.
43. Mestecky, J., M. W. Russell, and C. O. Elson. 1999. Intestinal IgA: novel views on its function in the defence of the largest mucosal surface. Gut. 44: 2-5.
44. Pasquier, B., P. Launay, Y. Kanamaru, I. C. Moura, S. Pfirsch, C. Ruffle, D. Henin, M. Benhamou, M. Pretolani, U. Blank, and R. C. Monteiro. 2005. Identification of FcαRI as an inhibitory receptor that controls inflammation: dual role of FcRγ ITAM. Immunity 22: 31-42.
45. Geissmann, F., P. Launay, B. Pasquier, Y. Lepelletier, M. Leborgne, A. Lehuen, N. Brousse, and R. C. Monteiro. 2001. A subset of human dendritic cells expresses IgA Fc receptor (CD89), which mediates internalization and activation upon cross-linking by IgA complexes. J. Immunol. 166: 346-352.
46. Heystek, H. C., C. Moulon, A. M. Woltman, P. Garonne, and C. van Kooten. 2002. Human immature dendritic cells efficiently bind and take up secretory IgA without the induction of maturation. J. Immunol. 168: 102-107.
47. Macpherson, A. J., L. Hunziker, K. McCoy, and A. Lamarre. 2001. IgA responses in the intestinal mucosa against pathogenic and non-pathogenic microorganisms. Microbes Infect. 3: 1021-1035.
48. Wu, H. Y., and H. L. Weiner. 2003. Oral tolerance. Immunol. Res. 28: 265-284.
49. Roy, M. J., and M. Varvayanis. 1987. Developmenr of dome epithelium in gut-associated lymphoid tissues: association of IgA with M cells. Cell Tissue Res. 248: 645-651.
50. Kato, T. 1990. A study of secretory immunoglobulin A on membranous epithelial cells (M cells) and adjacent absorptive cells of rabbit Peyer's parches. Gastroenterol. Jpn. 25: 15-23.
51. Weltzin, R., P. Lucia-Jandris, P. Michetti, B. N. Fields, J. P. Kraehenbuhl, and M. R. Neutra. 1989. Binding and transepithelial transport of immunoglobulins by intestinal M cells: demonstration using monoclonal IgA antibodies against enteric viral proteins. J. Cell Biol. 108: 1673-1685.
52. Mantis, N. J., M. C. Cheung, K. R. Chintalacharuvu, J. Rey, B. Corthésy, and M. R. Neutra. 2002. Selective adherence of IgA to murine Peyer's patch M cells: evidence for a novel IgA receptor. J. Immunol. 169: 1844-1851.
53. Mostov, K. E., M. Friedlander, and G. Blobel. 1984. The receptor for transepithelial transport of IgA and IgM contains multiple immunoglobulin-like domains. Nature 308: 37-43.
54. Shibuya, A., N. Sakamoto, Y. Shimizu, K. Shibuya, M. Osawa, T. Hiroyama, H. J. Eyre, G. R. Sutherland, Y. Endo, T. Fujita, et al. 2000. Fcα/μ receptor mediates endocytosis of IgM-coated microbes. Nat. Immunol. 1: 441-446.
55. Monteiro, R. C., and G. J. Van De Winkel. 2003. IgA Fc receptors. Annu. Rev. Immunol. 21: 177-204.
56. Tomana, M., R. Kulhavy, and J. Mestecky. 1988. Receptor-mediated binding and uptake of immunoglobulin A by human liver. Gastroenterology 94: 762-770.
57. Rey, J., N. Garin, F. Spertini, and B. Corthésy. 2004. Targeting of secretory IgA to Peyer's patch dendritic and T cells after transport by intestinal M cells. J. Immunol. 172: 3026-3033.
58. Corthésy, B., M. Kaufmann, A. Phalipon, M. Peitsch, M. R. Neutra, and J. P. Kraehenbuhl. 1996. A pathogen-specific epitope inserted into recombinant secretory immunoglobulin A is immunogenic by the oral route. J. Biol. Chem. 271: 33670-33677.
59. Favre, L. I., F. Spertini, and B. Corthésy. 2005. Secretory IgA possesses intrinsic modulatory properties stimulating mucosal and systemic immune responses. J. Immunol. 175: 2793-2800.
60. Chirdo, F. G., O. R. Millington, H. Beacock-Sharp, and A. M. Mowat. 2005. Immunomodulatory dendritic cells in intestinal lamina propria. Eur. J. Immunol. 35: 1831-1840.
61. + Peyer's patch dendritic cells secrete IL-6 and induce IgA secretion from naive B cells. J. Immunol. 171: 3684-3690.
62. Liu, L. M., and G. G. MacPherson. 1995. Rat intestinal dendritic cells: immunostimulatory potency and phenotypic characterization. Immunology 85: 88-93.
63. Blander, J. M., and R. Medzhitov. 2006. Toll-dependent selection of microbial antigens for presentation by dendritic cells. Nature 440: 808-812.
64. Wijburg, O. L., T. K. Uren, K. Simpfendorfer, F. E. Johansen, P. Brandtzaeg, and R. A. Strugnell. 2006. Innate secretory antibodies protect against natural Salmonella typhimurium infection. J. Exp. Med. 203: 21-26.
65. Johansen, F. E., M. Pekna, I. N. Norderhaug, B. Haneberg, M. A. Hietala, P. Krajci, C. Betsholtz, and P. Brandtzaeg. 1999. Absence of epithelial immunoglobulin A transport, with increased mucosal leakiness, in polymeric immunoglobulin receptor/secretory component-deficient mice. J. Exp. Med. 190: 915-922.
66. Bos, N. A., J. C. Bun, S. H. Popma, E. R. Cebra, G. J. Deenen, M. J. van der Cammen, F. G. Kroese, and J. J. Cebra. 1996. Monoclonal immunoglobulin A derived from peritoneal B cells is encoded by both germ line and somatically mutated VH genes and is reactive with commensal bacteria. Infect. Immun. 64: 616-623.
67. Macpherson, A. J., D. Gatto, E. Sainsbury, G. R. Harriman, H. Hengartner, and R. M. Zinkernagel. 2000. A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria. Science 288: 2222-2226.
68. van det Waaij, L. A., P. C. Limburg, G. Mesander, and D. van der Waaij. 1996. In vivo IgA coating of anaerobic bacteria in human faeces. Gut 38: 348-354.
69. Macpherson, A. J., and T. Uhr. 2004. Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria. Science 303: 1662-1665.
70. Shroff, K. E., K. Meslin, and J. J. Cebra. 1995. Commensal enteric bacteria engender a self-limiting humoral mucosal immune response while permanently colonizing the gut. Infect. Immun. 63: 3904-3913.
71. Mestecky, J. 1987. The common mucosal immune system and current strategies for induction of immune responses in external secretions. J. Clin. Immunol. 7: 265-276.
72. Hanson, L. A. 1998. Breastfeeding provides passive and likely long-lasting active immunity. Ann. Allergy Asthma Immunol. 81: 523-533.
73. Mata, L. J., J. J. Urrutia, B. Garcia, R. Fernandez, and M. Behar. 1969. Shigella infection in breast-fed Guatemalan Indian neonates. Am. J. Dis. Child. 117: 142-146.
74. Numazaki, K. 1997. Human cytomegalovirus infection of breast milk. FEMS Immunol. Med. Microbiol. 18: 91-98.
75. Boren, T., P. Falk, K. A. Roth, G. Larson, and A. Normark. 1993. Attachment of Helicobacter pylori to human gastric epithelium mediated by blood group antigens. Science 262: 1892-1895.
76. Wold, A. E., J. Mestecky, M. Tomana, A. Kobata, H. Ohbayashi, T. Endo, and C. S. Eden. 1990. Secretory immunoglobulin A carries oligosaccharide receptors for Escherichia coli type 1 fimbrial lectin. Infect. Immun. 58: 3073-3077.
77. Schroten, H., C. Stapper, R. Plogmann, H. Kohler, J. Hacket, and F. G. Hanisch. 1998. Fab-independent anti-adhesion effects of secretory immunoglobulin A on S-fimbriated Escherichia coli are mediated by sialyloligosacchatides. Infect. Immun. 66: 3971-3973.
78. Mantis, N. J., S. A. Fartant, and S. Mehta. 2004. Oligosaccharide side chains on human secretory IgA serve as receptors for ricin. J. Immunol. 172: 6838-6845.
79. Dallas, S. D., and R. D. Rolfe. 1998. Binding of Clostridium difficile toxin A to human milk secretory component. J. Med. Microbiol 47: 879-888.
80. Lu, L., M. E. Lamm, V. Li, B. Corthésy, and J. R. Zhang, 2003. The human polymeric immunoglobulin receptor binds to Streptococcus pneumoniae via domains 3 and 4. J. Biol. Chem. 278: 48178-48187.
81. Pettier, C., N. Sprenger, and B. Corthésy. 2006. Glycans on secretory component participate in innate protection against mucosal pathogens. J. Biol. Chem. 281: 14280-14287.
82. Hanson, L. A., M. Korotkova, S. Lundin, L. Haversen, S. A. Silfverdal, I. Mattsby-Baltzer, B. Strandvik, and E. Telemo. 2002. The transfer of immunity from mother to child. Ann. NY Acad. Sci. 987: 199-206.
83. Mowat, A. M. 2003. Anatomical basis of tolerance and immunity to intestinal antigens. Nat. Rev. Immunol. 3: 331-341.
84. Yoshida, M., S. M. Claypool, J. S. Wagner, E. Mizoguchi, A. Mizoguchi, D. C. Roopenian, W. I. Lencer, and R. S. Blumberg. 2004. Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells. Immunity 20: 769-783.
85. Rimoldi, M., M., Chieppa, V. Salucci, F., Avogadri, A. Sonzogni, G. M. Sampietto, A. Nespoli, G. Viale, P. Allavena, and M. Rescigno. 2005. Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells. Nat. Immunol 6: 507-514.
86. Salazar-Gonzalez, R. M., J. H. Niess, D. J. Zammit, R. Ravindran, A. Srinivasan, J. R. Maxwell, T. Stoklasek, R. Yadav, I. R. Williams, X. Gu, et al. 2006. CCR6-mediated dendritic cell activation of pathogen-specific T cells in Peyet's patches. Immunity 24: 623-632.
87. Niess, J. H., S. Brand, X. Gu, L. Landsman, S. Jung, B. A. McCormick, J. M. Vyas, M. Boes, H. L. Ploegh, J. G. Fox, et al. 2005. CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science 307: 254-258.