A mucosal IgA-mediated excretory immune system in vivo

Journal of Immunology

Volumn 166, Issue 6, 2001, Pages 3688-3692

  Robinson, J K ^a   Blanchard, T G ^a   Levine, A D ^a   Emancipator, S N ^a   Lamm, M E ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; BASOLATERAL MEMBRANE; CONTROLLED STUDY; IMMUNE SYSTEM; IMMUNIZATION; INTESTINE CRYPT; INTESTINE EPITHELIUM CELL; INTESTINE VILLUS; LAMINA PROPRIA; MOUSE; MUCOSA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE;

EID: 0035869274     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.6.3688     Document Type: Article

References (28)

1. Immunobiology and immunopathology of human gut mucosa: Humoral immunity and intraepithelial lymphocytes
2. Contribution of immunoglobulin-secreting cells in the murine small intestine to the "background" immunoglobulin production
3. The elimination of circulating complexes containing polymeric IgA by excretion in the bile
4. Role of serum IgA: Hepatobiliary transport of circulating antigen
5. Secretory component-dependent hepatic transport of IgA antibody-antigen complexes
6. Immunoglobulin transport and the polymeric immunoglobulin receptor
7. Biological activities of IgA
8. The polymeric immunoglobulin receptor (secretory component) mediates transport of immune complexes across epithelial cells: A local defense function of IgA
9. Epithelial transcytosis of monomeric IgA and IgG cross-linked through antigen to polymeric IgA: A role for monomeric antibodies in the mucosal immune system
10. lo thymocytes in vivo
11. Restoration oft cell development in RAG-2-deficient mice by functional TCR transgenes
12. Generalized systemic and mucosal immunity in mice after mucosal stimulation with cholera toxin
13. Induction of specific immunoglobulin A in the small intestine, colon-rectum, and vagina measured by a new method for collection of secretions from local mucosal surfaces
14. Detection of specific antigen within circulating immune complexes: Validation of the assay and its application to food antigen-antibody complexes found in healthy and food-allergic subjects
15. Passage of undegraded dietary antigen into the blood of healthy adults: Quantitation, estimation of size distribution, and relation of uptake to levels of specific antibodies
16. Macromolecular transport by rat gastric mucosa
17. Localization of b markers, α chain and SC of sIgA in epithelial cells lining Lieberkuhn crypts
18. Localization of free and bound secretory component in human intestinal epithelial cells: A model for the assembly of secretory IgA
19. Mucosal and glandular distribution of immunoglobulin components: Immunohistochemistry with a cold ethanol-fixation technique
20. Mechanism for enhanced external transfer of dimeric IgA over pentameric IgM: Studies of diffusion, binding to the human polymeric Ig receptor, and epithelial transcytosis
21. Epithelial cell polarization is a determinant in the infectious outcome of immunoglobulin A-mediated entry by Epstein-Barr virus
22. IgA nephropathy and related diseases
23. Intracellular neutralization of virus by immunoglobulin A antibodies
24. Intracellular neutralization of influenza virus by IgA anti-HA monoclonal antibodies
25. Immunocytochemical colocalization of specific immunoglobulin A with Sendai virus protein in infected polarized epithelium
26. Protective effect of rotavirus VP6-specific IgA monoclonal antibodies that lack neutralizing activity
27. Intracellular neutralization of HIV transcytosis across tight epithelial barriers by anti-HIV envelope protein dIgA or IgM
28. Interaction of antigens and antibodies at mucosal surfaces