Binding of Clostridium difficile toxin A to human milk secretory component

Journal of Medical Microbiology

Volumn 47, Issue 10, 1998, Pages 879-888

  Dallas, S D ^a   Rolfe, R D ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLOSTRIDIUM DIFFICILE TOXIN A; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; IMMUNOGLOBULIN M; MEMBRANE RECEPTOR; MILK PROTEIN; SECRETORY IMMUNOGLOBULIN;

ARTICLE; AUTORADIOGRAPHY; BREAST MILK; CLOSTRIDIUM DIFFICILE; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; HUMAN; HUMAN CELL; INTESTINE BRUSH BORDER MEMBRANE; ISOTOPE LABELING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING;

EID: 0031762948     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/00222615-47-10-879     Document Type: Article

References (48)

1. Bartlett JG. Clostridium difficile: history of its role as an enteric pathogen and the current state of knowledge about the organism. Clin Infect Dis 1994; 18 (Suppl 4): S265-272.
2. Bennett RG. Clostridium difficile infection in the elderly. In: Rambaud J-C, LaMont JT (eds) Updates on Clostridium difficile. Paris, Springer-Verlag. 1996: 15-27.
3. LaMont TJ. Recent advances in the structure and function of Clostridium difficile toxins. In: Rambaud J-C, LaMont TJ (eds) Updates on Clostridium difficile. Paris. Springer-Verlag. 1996: 73-82.
4. Moncrief JS, Lyerly DM, Wilkins TD. Molecular biology of the Clostridium difficile toxins. In: Rood JI, McClane BA, Songer JG, Titball RW (eds) The Clostridia: molecular biology and pathogenesis. San Diego, Academic Press. 1997: 369-392.
5. Kelly CP, Becker S, Linevsky JK et al. Neutrophil recruitment in Clostridium difficile toxin A enteritis in the rabbit. J Clin Invest 1994; 93: 1257-1265.
6. Lyerly DM, Wilkins TD. Purification and properties of toxins A and B of Clostridium difficile. In: Rolfe RD, Finegold SM (eds) Clostridium difficile: its role in intestinal disease. San Diego, Academic Press. 1988: 145-167.
7. Clark GF, Krivan HC, Wilkins TD, Smith DF. Toxin A from Clostridium difficile binds to rabbit erythrocyte glycolipids with terminal Ga1α1-3Galβ1-4GlcNAc sequences. Arch Biochem Biophys 1987; 257: 217-229.
8. Krivan HC, Clark GF, Smith DF, Wilkins TD. Cell surface binding site for Clostridium difficile enterotoxin: evidence for a glycoconjugate containing the sequence Galα1-3Galβ1-4-GlcNAc. Infect Immun 1986; 53: 573-581.
9. Rolfe RD. Binding kinetics of Clostridium difficile toxins A and B to intestinal brush border membranes from infant and adult hamsters. Infect Immun 1991; 59: 1223-1230.
10. Rolfe RD, Song W. Purification of a functional receptor for Clostridium difficile toxin A from intestinal brush border membranes of infant hamsters. Clin Infect Dis 1993; 16 (Suppl 4): S219-S227.
11. Wolfhagen MJHM, Torensma R, Fluit AC, Aarsman CJM, Jansze M, Verhoef J. Multivalent binding of toxin A from Clostridium difficile to carbohydrate receptors. Toxicon 1994; 32: 129-132.
12. Tucker KD, Wilkins TD. Toxin A of Clostridium difficile binds to the human carbohydrate antigens I, X, and Y. Infect Immun 1991; 59: 73-78.
13. Cooperstock M. Clostridium difficile in infants and children. In: Rolfe RD, Finegold SM (eds) Clostridium difficile: its role in intestinal disease. San Diego, Academic Press. 1988: 45-64.
14. Nash JQ, Chattopadhyay B, Honeycombe J, Tabaqchali S. Clostridium difficile and cytotoxin in routine faecal specimens. J Clin Pathol 1982; 35: 561-565.
15. Stark PL, Lee A, Parsonage BD. Colonization of the large bowel by Clostridium difficile in healthy infants: quantitative study. Infect Immun 1982; 35: 895-899.
16. Cooperstock M, Riegle L, Woodruff CW, Onderdonk A. Influence of age, sex, and diet on asymptomatic colonization of infants with Clostridium difficile. J Clin Microbiol 1983; 17: 830-833.
17. Rolfe RD, Dallas SD. Investigations into the mechanisms of asymptomatic intestinal colonization of infants by toxigenic Clostridium difficile. Microecology Therapy 1995; 25: 209-222.
18. Rolfe RD, Iaconis JP. Intestinal colonization of infant hamsters with Clostridium difficile. Infect Immun 1983; 42: 480-486.
19. Kim K, Pickering LK, DuPont HL, Sullivan N, Wilkins T. In vitro and in vivo neutralizing activity of human colostrum and milk against purified toxins A and B of Clostridium difficile. J Infect Dis 1984; 150: 57-62.
20. Crane JK, Azar SS, Stam A, Newburg DS. Oligosaccharides from human milk block binding and activity of the Escherichia coli heat-stable enterotoxin (Sta) in T84 intestinal cells. J Nutr 1994; 124: 2358-2364.
21. Giugliano LG, Ribeiro STG, Vainstein MH, Ulhoa CJ. Free secretory component and lactoferrin of human milk inhibit the adhesion of enterotoxigenic Escherichia coli. J Med Microbiol 1995; 42: 3-9.
22. Laegreid A, Kolst Otnaess A-B. Trace amounts of ganglioside GM1 in human milk inhibit enterotoxins from Vibrio cholerae and Escherichia coli. Life Sci 1987; 40: 55-62.
23. Rolfe RD, Song W. Immunoglobulin and non-immunoglobulin components of human milk inhibit Clostridium difficile toxin A-receptor binding. J Med Microbiol 1995; 42: 10-19.
24. Bjork I, Lindh E. Gross conformation of human secretory immunoglobulin A and its component parts. Eur J Biochem 1974; 45: 135-145.
25. Eiffert H, Quentin E, Wiederhold M et al. Determination of the molecular structure of the human free secretory component. Biol Chem Hoppe Seyler 1991; 372: 119-128.
26. Fallgreen-Gebauer E, Gebauer W, Bastian A et al. The covalent linkage of secretory component to IgA. Structure of sIgA. Biol Chem Hoppe Seyler 1993; 374: 1023-1028.
27. Tomasi TB. Structure and function of mucosal antibodies. Annu Rev Med 1970; 21 281-298.
28. Ogra SS, Ogra PL. Immunologic aspects of human colostrum and milk. I. Distribution characteristics and concentrations of immunoglobulins at different times after the onset of lactation. J Pediatr 1978; 92: 546-549.
29. Mizoguchi A, Mizuochi T, Kobata A. Structures of the carbohydrate moieties of secretory component purified from human milk. J Biol Chem 1982; 257: 9612-9621.
30. Davidson LA, Lonnerdal B. Persistence of human milk proteins in the breast-fed infant. Acta Paediatr Scand 1987; 76: 733-740.
31. Eschenburg G, Heine W, Peters E. [Fecal sIgS and lysozyme excretion in breast feeding and formula feeding.] Kinderarztlh Prax 1990; 58: 255-260.
32. Goldman AS. The immune system of human milk: antimicrobial, antinflammatory and immunomodulating properties. Pediatr Infect Dis J 1993; 12: 664-671.
33. Jatsyk GV, Kuvaeva IB, Gribakin SG. Immunological protection of the neonatal gastrointestinal tract: the importance of breast feeding. Acta Paediatr Scand 1985; 74: 246-249.
34. Brown JG. Physiology of toxin A production by Clostridium difficile. Doctoral dissertation, Texas Tech University Health Sciences Center, 1991: 11-13.
35. Krivan HC, Wilkins TD. Purification of Clostridium difficile toxin A by affinity chromatography on immobilized thyroglobulin. Infect Immun 1987; 55: 1873-1877.
36. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with Folin phenol reagent. J Biol Chem 1951; 193: 265-275.
37. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680-685.
38. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979; 76: 4350-4354.
39. Abramovitz A. Preparative electrophoresis in the SE 600 vertical slab unit: a simple modification. Hoefer Scientific Instruments technical bulletin. 1990, #116.
40. Ammann AJ, Stiehm ER. Immune globulin levels in colostrum and breast milk, and serum from formula and breast-fed newborns. Proc Soc Exp Biol Med 1966; 122: 1098-1100.
41. Onderdonk AB. Role of the hamster model of antibiotic-associated colitis in defining the etiology of the disease In: Rolfe RD, Finegold SM (eds) Clostridium difficile: its role in intestinal disease. San Diego, Academic Press. 1988: 115-125.
42. Underdown BJ, DeRose J, Koczekan K, Socken D, Weicker J. Isolation of human secretory component by affinity chromatography on IgM-sepharose. Immunochemistry 1977; 14: 111-118.
43. Prentice A, Ewing G, Roberts SB et al. The nutritional role of breast-milk IgA and lactoferrin. Acta Paediatr Scand 1987; 76: 592-598.
44. Sabharwal H, Sjoblad S, Lundblad A. Sialylated oligosaccharides in human milk and feces of preterm, full-term, and weanling infants. J Pediatr Gastroenterol Nutr 1991; 12: 480-484.
45. Whyte RK, Homer R, Pennock CA. Faecal excretion of oligosaccharides and other carbohydrates in normal neonates. Arch Dis Child 1978; 53: 913-915.
46. Cheng SH. Inhibition of C. difficile toxin A receptor binding by cow's milk, cow's formula, and soy formula. Masters thesis, Texas Tech University Health Sciences Center, 1996.
47. Surawicz CM. Updates on the management of Clostridium difficile associated intestinal disease. In: Rambaud J-C, LaMont JT (eds) Updates on Clostridium difficile. Paris, Springer-Verlag. 1996: 105-115.
48. Buts JP, Bernasconi P, Vaerman JP, Dive C. Stimulation of secretory IgA and secretory component of immunoglobulins in small intestine of rats treated with Saccharomyces boulardii. Dig Dis Sci 1990; 35: 251-256.