-
1
-
-
0141750434
-
Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening
-
AZA-BLANC, P., COOPER, C.L., WAGNER, K., BATALOV, S., DEVERAUX, Q.L., and COOKE, M.P. (2003). Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening. Mol. Cell 12, 627-637.
-
(2003)
Mol. Cell
, vol.12
, pp. 627-637
-
-
AZA-BLANC, P.1
COOPER, C.L.2
WAGNER, K.3
BATALOV, S.4
DEVERAUX, Q.L.5
COOKE, M.P.6
-
2
-
-
12144289681
-
A large-scale RNAi screen in human cells identifies new components of the p53 pathway
-
BERNS, K., HIJMANS, E.M., MULLENDERS, J., BRUMMELKAMP, T.R., VELDS, A., HEIMERIKX, M., KERKHOVEN, R.M., MADIREDJO, M., NIJKAMP, W., WEIGELT, B., AGAMI, R., GE, W., CAVET, G., LINSLEY, P.S., BEIJERSBERGEN, R.L., and BERNARDS, R. (2004). A large-scale RNAi screen in human cells identifies new components of the p53 pathway. Nature 428, 431-437.
-
(2004)
Nature
, vol.428
, pp. 431-437
-
-
BERNS, K.1
HIJMANS, E.M.2
MULLENDERS, J.3
BRUMMELKAMP, T.R.4
VELDS, A.5
HEIMERIKX, M.6
KERKHOVEN, R.M.7
MADIREDJO, M.8
NIJKAMP, W.9
WEIGELT, B.10
AGAMI, R.11
GE, W.12
CAVET, G.13
LINSLEY, P.S.14
BEIJERSBERGEN, R.L.15
BERNARDS, R.16
-
3
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
BERNSTEIN, E., CAUDY, A.A., HAMMOND, S.M., and HANNON, G.J. (2001). Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409, 363-366.
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
BERNSTEIN, E.1
CAUDY, A.A.2
HAMMOND, S.M.3
HANNON, G.J.4
-
4
-
-
0142259345
-
New tools for functional mammalian cancer genetics
-
BRUMMELKAMP, T.R., and BERNARDS, R. (2003). New tools for functional mammalian cancer genetics. Nat. Rev. Cancer 3, 781-789.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 781-789
-
-
BRUMMELKAMP, T.R.1
BERNARDS, R.2
-
5
-
-
0042467554
-
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB
-
BRUMMELKAMP, T.R., NIJMAN, S.M., DIRAC, A.M., and BERNARDS, R. (2003). Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB. Nature 424, 797-801.
-
(2003)
Nature
, vol.424
, pp. 797-801
-
-
BRUMMELKAMP, T.R.1
NIJMAN, S.M.2
DIRAC, A.M.3
BERNARDS, R.4
-
6
-
-
0042785949
-
EDD, the human orthologue of the hyperplastic discs tumour suppressor gene, is amplified and overexpressed in cancer
-
CLANCY, J.L., HENDERSON, M.J., RUSSELL, A.J., ANDERSON, D.W., BOVA, R.J., CAMPBELL, I.G., CHOONG, D.Y., MACDONALD, G.A., MANN, G.J., NOLAN, T., BRADY, G., OLOPADE, O.I., WOOLLATT, E., DAVIES, M.J., SEGARA, D., HACKER, N.F., HENSHALL, S.M., SUTHERLAND, R.L., and WATTS, C.K. (2003). EDD, the human orthologue of the hyperplastic discs tumour suppressor gene, is amplified and overexpressed in cancer. Oncogene 22, 5070-5081.
-
(2003)
Oncogene
, vol.22
, pp. 5070-5081
-
-
CLANCY, J.L.1
HENDERSON, M.J.2
RUSSELL, A.J.3
ANDERSON, D.W.4
BOVA, R.J.5
CAMPBELL, I.G.6
CHOONG, D.Y.7
MACDONALD, G.A.8
MANN, G.J.9
NOLAN, T.10
BRADY, G.11
OLOPADE, O.I.12
WOOLLATT, E.13
DAVIES, M.J.14
SEGARA, D.15
HACKER, N.F.16
HENSHALL, S.M.17
SUTHERLAND, R.L.18
WATTS, C.K.19
-
7
-
-
3543143101
-
Functional proteomics mapping of a human signaling pathway
-
COLLAND, F., JACQ, X., TROUPLIN, V., MOUGIN, C., GROIZELEAU, C., HAMBURGER, A., MEIL, A., WOJCIK, J., LEGRAIN, P., and GAUTHIER, J.M. (2004). Functional proteomics mapping of a human signaling pathway. Genome Res. 14, 1324-1332.
-
(2004)
Genome Res
, vol.14
, pp. 1324-1332
-
-
COLLAND, F.1
JACQ, X.2
TROUPLIN, V.3
MOUGIN, C.4
GROIZELEAU, C.5
HAMBURGER, A.6
MEIL, A.7
WOJCIK, J.8
LEGRAIN, P.9
GAUTHIER, J.M.10
-
8
-
-
3242677639
-
siRNAs: Applications in functional genomics and potential as therapeutics
-
DORSETT, Y., and TUSCHL, T. (2004). siRNAs: Applications in functional genomics and potential as therapeutics. Nat. Rev. Drug Discov. 3, 318-329.
-
(2004)
Nat. Rev. Drug Discov
, vol.3
, pp. 318-329
-
-
DORSETT, Y.1
TUSCHL, T.2
-
9
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
ELBASHIR, S.M., HARBORTH, J., LENDECKEL, W., YALCIN, A., WEBER, K., and TUSCHL, T. (2001). Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
ELBASHIR, S.M.1
HARBORTH, J.2
LENDECKEL, W.3
YALCIN, A.4
WEBER, K.5
TUSCHL, T.6
-
10
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
FIRE, A., XU, S., MONTGOMERY, M.K., KOSTAS, S.A., DRIVER, S.E., and MELLO, C.C. (1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806-811.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
FIRE, A.1
XU, S.2
MONTGOMERY, M.K.3
KOSTAS, S.A.4
DRIVER, S.E.5
MELLO, C.C.6
-
11
-
-
0034676448
-
Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III
-
GONCZY, P., ECHEVERRI, C., OEGEMA, K., COULSON, A., JONES, S.J., COPLEY, R.R., DUPERON, J., OEGEMA, J., BREHM, M., CASSIN, E., HANNAK, E., KIRKHAM, M., PICHLER, S., FLOHRS, K., GOESSEN, A., LEIDEL, S., ALLEAUME, A.M., MARTIN, C., OZLU, N., BORK, P., and HYMAN, A.A. (2000). Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III. Nature 408, 331-336.
-
(2000)
Nature
, vol.408
, pp. 331-336
-
-
GONCZY, P.1
ECHEVERRI, C.2
OEGEMA, K.3
COULSON, A.4
JONES, S.J.5
COPLEY, R.R.6
DUPERON, J.7
OEGEMA, J.8
BREHM, M.9
CASSIN, E.10
HANNAK, E.11
KIRKHAM, M.12
PICHLER, S.13
FLOHRS, K.14
GOESSEN, A.15
LEIDEL, S.16
ALLEAUME, A.M.17
MARTIN, C.18
OZLU, N.19
BORK, P.20
HYMAN, A.A.21
more..
-
12
-
-
4644350944
-
Unlocking the potential of the human genome with RNA interference
-
HANNON, G.J., and ROSSI, J.J. (2004). Unlocking the potential of the human genome with RNA interference. Nature 431, 371-378.
-
(2004)
Nature
, vol.431
, pp. 371-378
-
-
HANNON, G.J.1
ROSSI, J.J.2
-
13
-
-
0037089135
-
Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor
-
HOLEN, T., AMARZGUIOUI, M., WIIGER, M.T., BABAIE, E., and PRYDZ, H. (2002). Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor. Nucleic Acids Res. 30, 1757-1766.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 1757-1766
-
-
HOLEN, T.1
AMARZGUIOUI, M.2
WIIGER, M.T.3
BABAIE, E.4
PRYDZ, H.5
-
14
-
-
2342564353
-
A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: Determinants of gene silencing for use in cell-based screens
-
HSIEH, A.C., BO, R., MANOLA, I., VAZQUEZ, F., BARE, O., KHVOROVA, A., SCARINGE, S., and SELLERS, W.R. (2004). A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens. Nucleic Acids Res. 32, 893-901.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 893-901
-
-
HSIEH, A.C.1
BO, R.2
MANOLA, I.3
VAZQUEZ, F.4
BARE, O.5
KHVOROVA, A.6
SCARINGE, S.7
SELLERS, W.R.8
-
15
-
-
0037327444
-
siRNAs generated by recombinant human Dicer induce specific and significant but target site-independent gene silencing in human cells
-
KAWASAKI, H., SUYAMA, E., IYO, M., and TAIRA, K. (2003). siRNAs generated by recombinant human Dicer induce specific and significant but target site-independent gene silencing in human cells. Nucleic Acids Res. 31, 981-987.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 981-987
-
-
KAWASAKI, H.1
SUYAMA, E.2
IYO, M.3
TAIRA, K.4
-
16
-
-
0142165224
-
Functional siRNAs and miRNAs exhibit strand bias
-
KHVOROVA, A., REYNOLDS, A., and JAYASENA, S.D. (2003). Functional siRNAs and miRNAs exhibit strand bias. Cell 115, 209-216.
-
(2003)
Cell
, vol.115
, pp. 209-216
-
-
KHVOROVA, A.1
REYNOLDS, A.2
JAYASENA, S.D.3
-
17
-
-
0037031576
-
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
-
MARTINEZ, J., PATKANIOWSKA, A., URLAUB, H., LUHRMANN, R., and TUSCHL, T. (2002). Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110, 563-574.
-
(2002)
Cell
, vol.110
, pp. 563-574
-
-
MARTINEZ, J.1
PATKANIOWSKA, A.2
URLAUB, H.3
LUHRMANN, R.4
TUSCHL, T.5
-
18
-
-
0033615357
-
Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen
-
MAYER, T.U., KAPOOR, T.M., HAGGARTY, S.J., KING, R.W., SCHREIBER, S.L., and MITCHISON, T.J. (1999). Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen. Science 286, 971-974.
-
(1999)
Science
, vol.286
, pp. 971-974
-
-
MAYER, T.U.1
KAPOOR, T.M.2
HAGGARTY, S.J.3
KING, R.W.4
SCHREIBER, S.L.5
MITCHISON, T.J.6
-
19
-
-
0037111232
-
Small interfering RNA-mediated gene silencing in T lymphocytes
-
MCMANUS, M.T., HAINES, B.B., DILLON, C.P., WHITEHURST, C.E., VAN PARIJS, L., CHEN, I., and SHARP, P.A. (2002). Small interfering RNA-mediated gene silencing in T lymphocytes. J. Immunol. 169, 5754-5760.
-
(2002)
J. Immunol
, vol.169
, pp. 5754-5760
-
-
MCMANUS, M.T.1
HAINES, B.B.2
DILLON, C.P.3
WHITEHURST, C.E.4
VAN PARIJS, L.5
CHEN, I.6
SHARP, P.A.7
-
20
-
-
0036788304
-
Gene silencing in mammals by small interfering RNAs
-
MCMANUS, M.T., and SHARP, P.A. (2002). Gene silencing in mammals by small interfering RNAs. Nat. Rev. Genet. 3, 737-747.
-
(2002)
Nat. Rev. Genet
, vol.3
, pp. 737-747
-
-
MCMANUS, M.T.1
SHARP, P.A.2
-
21
-
-
12144288006
-
A resource for large-scale RNA-interference-based screens in mammals
-
PADDISON, P.J., SILVA, J.M., CONKLIN, D.S., SCHLABACH, M., LI, M., ARULEBA, S., BALIJA, V., O'SHAUGHNESSY, A., GNOJ, L., SCOBIE, K., CHANG, K., WESTBROOK, T., CLEARY, M., SACHIDANANDAM, R., MCCOMBIE, W.R., ELLEDGE, S.J., and HANNON, G.J. (2004). A resource for large-scale RNA-interference-based screens in mammals. Nature 428, 427-431.
-
(2004)
Nature
, vol.428
, pp. 427-431
-
-
PADDISON, P.J.1
SILVA, J.M.2
CONKLIN, D.S.3
SCHLABACH, M.4
LI, M.5
ARULEBA, S.6
BALIJA, V.7
O'SHAUGHNESSY, A.8
GNOJ, L.9
SCOBIE, K.10
CHANG, K.11
WESTBROOK, T.12
CLEARY, M.13
SACHIDANANDAM, R.14
MCCOMBIE, W.R.15
ELLEDGE, S.J.16
HANNON, G.J.17
-
22
-
-
1542336952
-
Rational siRNA design for RNA interference
-
REYNOLDS, A., LEAKE, D., BOESE, Q., SCARINGE, S., MARSHALL, W.S., and KHVOROVA, A. (2004). Rational siRNA design for RNA interference. Nat. Biotechnol. 22, 326-330.
-
(2004)
Nat. Biotechnol
, vol.22
, pp. 326-330
-
-
REYNOLDS, A.1
LEAKE, D.2
BOESE, Q.3
SCARINGE, S.4
MARSHALL, W.S.5
KHVOROVA, A.6
-
23
-
-
0026739078
-
Mitotic spindle organization by a plus-end-directed microtubule motor
-
SAWIN, K.E., LEGUELLEC, K., PHILIPPE, M., and MITCHISON, T.J. (1992). Mitotic spindle organization by a plus-end-directed microtubule motor. Nature 359, 540-543.
-
(1992)
Nature
, vol.359
, pp. 540-543
-
-
SAWIN, K.E.1
LEGUELLEC, K.2
PHILIPPE, M.3
MITCHISON, T.J.4
-
24
-
-
0032506226
-
Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA
-
WATERHOUSE, P.M., GRAHAM, M.W., and WANG, M.B. (1998). Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA. Proc. Natl. Acad. Sci. USA 95, 13959-13964.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13959-13964
-
-
WATERHOUSE, P.M.1
GRAHAM, M.W.2
WANG, M.B.3
-
25
-
-
0347928860
-
Targeting the kinesin Eg5 to monitor siRNA transfection in mammalian cells
-
WEIL, D., GARCON, L., HARPER, M., DUMENIL, D., DAUTRY, F., and KRESS, M. (2002). Targeting the kinesin Eg5 to monitor siRNA transfection in mammalian cells. Biotechniques 33, 1244-1248.
-
(2002)
Biotechniques
, vol.33
, pp. 1244-1248
-
-
WEIL, D.1
GARCON, L.2
HARPER, M.3
DUMENIL, D.4
DAUTRY, F.5
KRESS, M.6
-
26
-
-
9144273977
-
RNAi and HTS: Exploring cancer by systematic loss-of-function
-
WILLINGHAM, A.T., DEVERAUX, Q.L., HAMPTON, G.M., and AZA-BLANC, P. (2004). RNAi and HTS: exploring cancer by systematic loss-of-function. Oncogene 23, 8392-8400.
-
(2004)
Oncogene
, vol.23
, pp. 8392-8400
-
-
WILLINGHAM, A.T.1
DEVERAUX, Q.L.2
HAMPTON, G.M.3
AZA-BLANC, P.4
-
27
-
-
0037162522
-
Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells
-
YANG, D., BUCHHOLZ, F., HUANG, Z., GOGA, A., CHEN, C.Y., BRODSKY, P.M., and BISHOP, J.M. (2002). Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells. Proc. Natl. Acad. Sci. USA. 99, 9942-9947.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 9942-9947
-
-
YANG, D.1
BUCHHOLZ, F.2
HUANG, Z.3
GOGA, A.4
CHEN, C.Y.5
BRODSKY, P.M.6
BISHOP, J.M.7
-
28
-
-
0347089019
-
An approach to genome wide screens of expressed small interfering RNAs in mammalian cells
-
ZHENG, L., LIU, J., BATALOV, S., ZHOU, D., ORTH, A., DING, S., and SCHULTZ, P.G. (2004). An approach to genome wide screens of expressed small interfering RNAs in mammalian cells. Proc. Natl. Acad. Sci. USA. 101, 135-140.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 135-140
-
-
ZHENG, L.1
LIU, J.2
BATALOV, S.3
ZHOU, D.4
ORTH, A.5
DING, S.6
SCHULTZ, P.G.7
|