Assessment of cisplatin-induced nephrotoxicity by microarray technology

Toxicological Sciences

Volumn 63, Issue 2, 2001, Pages 196-207

  Huang, Qihong ^a   Dunn II, Robert T ^b   Jayadev, Supriya ^a   DiSorbo, Olimpia ^a   Pack, Franklin D ^a   Farr, Spencer B ^b   Stoll, Raymond E ^a   Blanchard, Kerry T ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^b Phase 1 Molecular Toxicology Inc   (United States)

Author keywords

Apoptosis; Cisplatin; Microarray; Nephrotoxicity; Real time PCR; Toxicogenomics

Indexed keywords

CALCIUM ION; CISPLATIN; CLUSTERIN; DNA; GLUCOSE; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; PROTEIN BAX; REGUCALCIN; SODIUM CHLORIDE; SOMATOMEDIN BINDING PROTEIN 1; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSPLATIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOCHEMISTRY; BIOLOGY; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CONTROLLED STUDY; DNA MICROARRAY; DOSE RESPONSE; DRUG SENSITIVITY; EPITHELIUM CELL; GENE EXPRESSION; GENETIC PROCEDURES; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY EPITHELIUM; KIDNEY NECROSIS; KIDNEY PROXIMAL TUBULE; LIVER CELL; LIVER TOXICITY; MALE; NEPHROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT; TISSUE REGENERATION; TOXICOLOGY; UNINDEXED SEQUENCE;

ANIMALS; BCL-2-ASSOCIATED X PROTEIN; CALCIUM-BINDING PROTEINS; CELL LINE; CISPLATIN; CLUSTERIN; EPITHELIAL CELLS; GENE EXPRESSION; GENES, MDR; GLYCOPROTEINS; HEPATOCYTES; INJECTIONS, INTRAPERITONEAL; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; KIDNEY; KIDNEY TUBULAR NECROSIS, ACUTE; LIVER; MALE; MOLECULAR CHAPERONES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; STEREOISOMERISM; SULFOTRANSFERASES; TIME FACTORS; TISSUE INHIBITOR OF METALLOPROTEINASE-1;

EID: 0034779861     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/63.2.196     Document Type: Article

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