Molecular dynamics simulation of the human adenosine A3 receptor: Agonist induced conformational changes of Trp243

Journal of Computer-Aided Molecular Design

Volumn 20, Issue 10-11, 2006, Pages 673-684

  Hallmen, Christian ^a   Wiese, Michael ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

Adenosine A3 receptor; GPCR; Molecular dynamics; Phospholipid bilayer; Receptor activation

Indexed keywords

CHEMICAL ACTIVATION; CRYSTAL STRUCTURE; LIGANDS; PHOSPHOLIPIDS;

ADENOSINE A3 RECEPTOR; CLASS A; CONFORMATIONAL CHANGE; DYNAMICS SIMULATION; G PROTEIN COUPLED RECEPTORS; GPCR; HOMOLOGY MODELING; INVERSE AGONISTS; PHOSPHOLIPIDS BILAYER; RECEPTOR ACTIVATION;

MOLECULAR DYNAMICS;

6 N (3 IODOBENZYL)ADENOSINE 5' N METHYLCARBOXAMIDE; ADENOSINE A3 RECEPTOR; ADENOSINE A3 RECEPTOR AGONIST; ADENOSINE RECEPTOR STIMULATING AGENT; ALAMETHICIN; G PROTEIN COUPLED RECEPTOR; PSB 10; RECEPTOR ACTIVITY MODIFYING PROTEIN; RHODOPSIN; TRYPTOPHAN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; DRUG RECEPTOR BINDING; HUMAN; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN STRUCTURE; RECEPTOR BINDING; STRUCTURE ANALYSIS;

EID: 33845900510     PISSN: 0920654X     EISSN: 15734951     Source Type: Journal    
DOI: 10.1007/s10822-006-9088-5     Document Type: Article

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