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Volumn 60, Issue 13, 2000, Pages 3384-3388

Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; TYROSINE KINASE RECEPTOR;

EID: 0034234854     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (305)

References (21)
  • 1
    • 0032549036 scopus 로고    scopus 로고
    • The ErbB-2/HER2 oncogenic receptor of adenocarcinomas: From orphanhood to multiple stromal ligands
    • Tzahar, E., and Yarden, Y. The ErbB-2/HER2 oncogenic receptor of adenocarcinomas: from orphanhood to multiple stromal ligands. Biochem. Biophys. Acta. Rev. Cancer. 1377: M25-M37, 1998.
    • (1998) Biochem. Biophys. Acta. Rev. Cancer. , vol.1377
    • Tzahar, E.1    Yarden, Y.2
  • 2
    • 0028670125 scopus 로고
    • The biology of erbB-2/neu/HER-2 and its role in cancer
    • Hynes, N. E., and Stern, D. F. The biology of erbB-2/neu/HER-2 and its role in cancer. Biochem. Biophys. Acta, 1198: 165-184, 1994.
    • (1994) Biochem. Biophys. Acta , vol.1198 , pp. 165-184
    • Hynes, N.E.1    Stern, D.F.2
  • 4
    • 0000405942 scopus 로고    scopus 로고
    • Addition of herceptin (humanized anti-HER2 antibody) to first line chemotherapy for HER2 overexpressing metastatic breast cancer (HER2+/MCB) markedly increases anticancer activity: A randomized, multinational controlled phase III trial
    • Slamon, D., Levland-Jones, B., and Shak, S. E. A. Addition of Herceptin (humanized anti-HER2 antibody) to first line chemotherapy for HER2 overexpressing metastatic breast cancer (HER2+/MCB) markedly increases anticancer activity: a randomized, multinational controlled phase III trial. Proc. Am. Soc. Clin. Oncol., 17: 98a, 1998.
    • (1998) Proc. Am. Soc. Clin. Oncol. , vol.17
    • Slamon, D.1    Levland-Jones, B.2    Shak, S.E.A.3
  • 5
    • 0030959114 scopus 로고    scopus 로고
    • A subclass of tumor-inhibitory monoclonal antibodies to ErbB-2/HER2 blocks crosstalk with growth factor receptors
    • Klapper, L. N., Vaisman, N., Hurwitz, E., Pinkas Kramarski, R., Yarden, Y., and Sela, M. A subclass of tumor-inhibitory monoclonal antibodies to ErbB-2/HER2 blocks crosstalk with growth factor receptors. Oncogene, 14: 2099-2109, 1997.
    • (1997) Oncogene , vol.14 , pp. 2099-2109
    • Klapper, L.N.1    Vaisman, N.2    Hurwitz, E.3    Pinkas Kramarski, R.4    Yarden, Y.5    Sela, M.6
  • 6
    • 0026685034 scopus 로고
    • Therapy of an animal model of human gastric cancer using a combination of anti-erbB-2 monoclonal antibodies
    • Kasprzyk, P. G., Song, S. U., Di Fiore, P. P., and King, C. R. Therapy of an animal model of human gastric cancer using a combination of anti-erbB-2 monoclonal antibodies. Cancer Res., 52: 2771-2776, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 2771-2776
    • Kasprzyk, P.G.1    Song, S.U.2    Di Fiore, P.P.3    King, C.R.4
  • 7
    • 0028912598 scopus 로고
    • Suppression and promotion of tumor growth by monoclonal antibodies to ErbB-2 differentially correlate with cellular uptake
    • Hurwitz, E., Stancovski, I., Sela, M., and Yarden, Y. Suppression and promotion of tumor growth by monoclonal antibodies to ErbB-2 differentially correlate with cellular uptake. Proc. Natl. Acad. Sci. USA, 92: 3353-3357, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3353-3357
    • Hurwitz, E.1    Stancovski, I.2    Sela, M.3    Yarden, Y.4
  • 9
    • 0033536637 scopus 로고    scopus 로고
    • The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase
    • Washington DC
    • Joazeiro, C. A. P., Wing, S. S., Huang, H-K., Leverson, J. D., Hunter, T., and Liu, Y-C. The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase. Science (Washington DC), 286: 309-312, 1999.
    • (1999) Science , vol.286 , pp. 309-312
    • Joazeiro, C.A.P.1    Wing, S.S.2    Huang, H.-K.3    Leverson, J.D.4    Hunter, T.5    Liu, Y.-C.6
  • 11
    • 0031759356 scopus 로고    scopus 로고
    • c-Cbl: A regulator of T cell receptor-mediated signaling
    • Thien, C. B. F., and Langdon, W. c-Cbl: a regulator of T cell receptor-mediated signaling. Immunol. Cell Biol., 76: 473-482, 1998.
    • (1998) Immunol. Cell Biol. , vol.76 , pp. 473-482
    • Thien, C.B.F.1    Langdon, W.2
  • 12
    • 0032493444 scopus 로고    scopus 로고
    • The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor α
    • Miyake, S., Lupher, M. L., Jr. Druker, B., and Band, H. The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor α. Proc. Natl. Acad. Sci. USA, 95: 7927-7932, 1998.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 7927-7932
    • Miyake, S.1    Lupher M.L., Jr.2    Druker, B.3    Band, H.4
  • 13
    • 0033605560 scopus 로고    scopus 로고
    • ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors
    • Worthylake, R., Opresko, L. K., and Wiley, H. S. ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors. J. Biol. Chem., 274: 8865-8874, 1999
    • (1999) J. Biol. Chem. , vol.274 , pp. 8865-8874
    • Worthylake, R.1    Opresko, L.K.2    Wiley, H.S.3
  • 15
    • 0032579005 scopus 로고    scopus 로고
    • Heregulin β1 induces the down-regulation and the ubiquitin-proteasome degradation pathway of p185HER2 oncoprotein
    • Magnifico, A., Tagliabue, E., Ardini, E., Casalini, P., Colnaghi, M. I., and Menard, S. Heregulin β1 induces the down-regulation and the ubiquitin-proteasome degradation pathway of p185HER2 oncoprotein. FEBS Lett., 422: 129-131, 1998.
    • (1998) FEBS Lett. , vol.422 , pp. 129-131
    • Magnifico, A.1    Tagliabue, E.2    Ardini, E.3    Casalini, P.4    Colnaghi, M.I.5    Menard, S.6
  • 16
    • 0024505028 scopus 로고
    • A point mutation in the neu oneogene mimics ligand induction of receptor aggregation
    • Weiner, D. B., Liu, J., Cohen, J. A., Williams, W. V., and Greene, M. I. A point mutation in the neu oneogene mimics ligand induction of receptor aggregation. Nature (Lond.), 339: 230-231, 1989.
    • (1989) Nature (Lond.) , vol.339 , pp. 230-231
    • Weiner, D.B.1    Liu, J.2    Cohen, J.A.3    Williams, W.V.4    Greene, M.I.5
  • 17
    • 0032860819 scopus 로고    scopus 로고
    • Controlled dimerization of ErbB receptors provide evidence for differential signaling by homo-and heteriodimers
    • Muthuswamy, S. K., Gilman, M., and Brugge, J. Controlled dimerization of ErbB receptors provide evidence for differential signaling by homo-and heteriodimers. Mol. Cell. Biol., 19: 6845-6857, 1999.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 6845-6857
    • Muthuswamy, S.K.1    Gilman, M.2    Brugge, J.3
  • 18
    • 0033522219 scopus 로고    scopus 로고
    • Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase
    • Meng, W., Sawasdikosol, S., Burakoff, S. J., and Eck, M. J. Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase. Nature (Lond.), 398: 84-90, 1999.
    • (1999) Nature (Lond.) , vol.398 , pp. 84-90
    • Meng, W.1    Sawasdikosol, S.2    Burakoff, S.J.3    Eck, M.J.4
  • 19
    • 0029812759 scopus 로고    scopus 로고
    • Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin
    • Mimnaugh, E. G., Chavany, C., and Neckers, L. Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin. J. Biol. Chem., 271: 22796-22801, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 22796-22801
    • Mimnaugh, E.G.1    Chavany, C.2    Neckers, L.3
  • 20
    • 0029917264 scopus 로고    scopus 로고
    • Coupling of the c-Cbl protooncogene product to ErbB-1/EGF-receptor but not to other ErbB proteins
    • Levkowitz, G., Klapper, L. N., Tzahar, E., Freywald, A., Sela, M., and Yarden, Y. Coupling of the c-Cbl protooncogene product to ErbB-1/EGF-receptor but not to other ErbB proteins. Oncogene, 12: 1117-1125, 1996.
    • (1996) Oncogene , vol.12 , pp. 1117-1125
    • Levkowitz, G.1    Klapper, L.N.2    Tzahar, E.3    Freywald, A.4    Sela, M.5    Yarden, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.