메뉴 건너뛰기




Volumn 82, Issue 11, 2006, Pages 1484-1492

A potential side effect of cyclosporin A: Inhibition of CD4+CD25+ regulatory T cells in mice

Author keywords

Cyclosporin A; Immunosuppression; Regulatory T cells; Rodent

Indexed keywords

ALLOANTIGEN; CD45RB ANTIGEN; CYCLOSPORIN A; HERMES ANTIGEN; L SELECTIN; TRANSCRIPTION FACTOR FOXP3;

EID: 33845687004     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.tp.0000246312.89689.17     Document Type: Article
Times cited : (89)

References (60)
  • 1
    • 25844526684 scopus 로고    scopus 로고
    • Central tolerance: Learning self-control in the thymus
    • Hogquist KA, Baldwin TA, Jameson SC. Central tolerance: learning self-control in the thymus. Nat Rev Immunol 2005; 5(10): 772.
    • (2005) Nat Rev Immunol , vol.5 , Issue.10 , pp. 772
    • Hogquist, K.A.1    Baldwin, T.A.2    Jameson, S.C.3
  • 2
    • 2942672441 scopus 로고    scopus 로고
    • Cornerstone of peripheral tolerance: Naturally occurring CD4+CD25+ regulatory T cells
    • Piccirillo CA, Thornton AM. Cornerstone of peripheral tolerance: naturally occurring CD4+CD25+ regulatory T cells. Trends Immunol 2004; 25(7): 374.
    • (2004) Trends Immunol , vol.25 , Issue.7 , pp. 374
    • Piccirillo, C.A.1    Thornton, A.M.2
  • 3
    • 16844365788 scopus 로고    scopus 로고
    • Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
    • Sakaguchi S. Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immunol 2005; 6(4): 345.
    • (2005) Nat Immunol , vol.6 , Issue.4 , pp. 345
    • Sakaguchi, S.1
  • 4
    • 28444444122 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells limit the risk of autoimmune disease arising from T cell receptor cross-reactivity
    • Stephens LA, Gray D, Anderton SM. CD4+CD25+ regulatory T cells limit the risk of autoimmune disease arising from T cell receptor cross-reactivity. Proc Natl Acad Sci USA 2005; 102(48): 17418.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.48 , pp. 17418
    • Stephens, L.A.1    Gray, D.2    Anderton, S.M.3
  • 5
    • 0035180067 scopus 로고    scopus 로고
    • Control of intestinal inflammation by regulatory T cells
    • Singh B, Read S, Asseman C, et al. Control of intestinal inflammation by regulatory T cells. Immunol Rev 2001; 182: 190.
    • (2001) Immunol Rev , vol.182 , pp. 190
    • Singh, B.1    Read, S.2    Asseman, C.3
  • 6
    • 0035054606 scopus 로고    scopus 로고
    • Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro
    • Stephens LA, Mottet C, Mason D, Powrie F. Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro. Eur J Immunol 2001; 31(4): 1247.
    • (2001) Eur J Immunol , vol.31 , Issue.4 , pp. 1247
    • Stephens, L.A.1    Mottet, C.2    Mason, D.3    Powrie, F.4
  • 7
    • 0033136302 scopus 로고    scopus 로고
    • Thymus and autoimmunity: Production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
    • Itoh M, Takahashi T, Sakaguchi N, et al. Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J Immunol 1999; 162(9): 5317.
    • (1999) J Immunol , vol.162 , Issue.9 , pp. 5317
    • Itoh, M.1    Takahashi, T.2    Sakaguchi, N.3
  • 8
    • 0035180065 scopus 로고    scopus 로고
    • Immunologic tolerance maintained by CD25+CD4+ regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance
    • Sakaguchi S, Sakaguchi N, Shimizu J, et al. Immunologic tolerance maintained by CD25+CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev 2001; 182: 18.
    • (2001) Immunol Rev , vol.182 , pp. 18
    • Sakaguchi, S.1    Sakaguchi, N.2    Shimizu, J.3
  • 9
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 2003; 4(4): 330.
    • (2003) Nat Immunol , vol.4 , Issue.4 , pp. 330
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 10
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003; 299(5609): 1057.
    • (2003) Science , vol.299 , Issue.5609 , pp. 1057
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 11
    • 18644381392 scopus 로고    scopus 로고
    • Foxp3: A critical transcription factor for the development of regulatory T cells
    • Rao E, Zhao Y. Foxp3: a critical transcription factor for the development of regulatory T cells. Prog Biochem Biophy 2005; 32(2): 106.
    • (2005) Prog Biochem Biophy , vol.32 , Issue.2 , pp. 106
    • Rao, E.1    Zhao, Y.2
  • 12
    • 0029788211 scopus 로고    scopus 로고
    • Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation
    • Asano M, Toda M, Sakaguchi N, Sakaguchi S. Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J Exp Med 1996; 184(2): 387.
    • (1996) J Exp Med , vol.184 , Issue.2 , pp. 387
    • Asano, M.1    Toda, M.2    Sakaguchi, N.3    Sakaguchi, S.4
  • 13
    • 23144450643 scopus 로고    scopus 로고
    • Regulatory T cells: Development, function and role in autoimmunity
    • Lan RY, Ansari AA, Lian ZX, Gershwin ME. Regulatory T cells: development, function and role in autoimmunity. Autoimmun Rev 2005; 4(6): 351.
    • (2005) Autoimmun Rev , vol.4 , Issue.6 , pp. 351
    • Lan, R.Y.1    Ansari, A.A.2    Lian, Z.X.3    Gershwin, M.E.4
  • 14
    • 16244390854 scopus 로고    scopus 로고
    • Regulatory T cells and autoimmune disease
    • Paust S, Cantor H. Regulatory T cells and autoimmune disease. Immunol Rev 2005; 204: 195.
    • (2005) Immunol Rev , vol.204 , pp. 195
    • Paust, S.1    Cantor, H.2
  • 15
    • 0037364976 scopus 로고    scopus 로고
    • Regulatory T cells in transplantation tolerance
    • Wood KJ, Sakaguchi S. Regulatory T cells in transplantation tolerance. Nat Rev Immunol 2003; 3(3): 199.
    • (2003) Nat Rev Immunol , vol.3 , Issue.3 , pp. 199
    • Wood, K.J.1    Sakaguchi, S.2
  • 16
    • 19344373375 scopus 로고    scopus 로고
    • Tolerance in mixed chimerism - A role for regulatory cells?
    • Kurtz J, Wekerle T, Sykes M. Tolerance in mixed chimerism - a role for regulatory cells? Trends Immunol 2004; 25(10): 518.
    • (2004) Trends Immunol , vol.25 , Issue.10 , pp. 518
    • Kurtz, J.1    Wekerle, T.2    Sykes, M.3
  • 17
    • 0034077559 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells downregulate co-stimulatory molecules on antigen-presenting cells
    • Cederbom L, Hall H, Ivars F. CD4+CD25+ regulatory T cells downregulate co-stimulatory molecules on antigen-presenting cells. Eur J Immunol 2000; 30(6): 1538.
    • (2000) Eur J Immunol , vol.30 , Issue.6 , pp. 1538
    • Cederbom, L.1    Hall, H.2    Ivars, F.3
  • 18
    • 32844469349 scopus 로고    scopus 로고
    • Dendritic cells and (CD4+)CD25+ T regulatory cells: Crosstalk between two professionals in immunity versus tolerance
    • Chen W. Dendritic cells and (CD4+)CD25+ T regulatory cells: crosstalk between two professionals in immunity versus tolerance. Front Biosci 2006; 11: 1360.
    • (2006) Front Biosci , vol.11 , pp. 1360
    • Chen, W.1
  • 19
    • 29244482759 scopus 로고    scopus 로고
    • Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice
    • Tang Q, Adams JY, Tooley AJ, et al. Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nat Immunol 2006; 7(1): 83.
    • (2006) Nat Immunol , vol.7 , Issue.1 , pp. 83
    • Tang, Q.1    Adams, J.Y.2    Tooley, A.J.3
  • 20
    • 1642352670 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of cyclosporine: 20 Years of progress
    • Kahan BD. Therapeutic drug monitoring of cyclosporine: 20 years of progress. Transplant Proc 2004; 36 (2 Suppl): 378S.
    • (2004) Transplant Proc , vol.36 , Issue.2 SUPPL.
    • Kahan, B.D.1
  • 21
    • 25444531126 scopus 로고    scopus 로고
    • Rationale for T cell inhibition by cyclosporin a in major autoimmune diseases
    • Ferraccioli GF, Tomietto P, De Santis M. Rationale for T cell inhibition by cyclosporin A in major autoimmune diseases. Ann N Y Acad Sci 2005; 1051: 658.
    • (2005) Ann N Y Acad Sci , vol.1051 , pp. 658
    • Ferraccioli, G.F.1    Tomietto, P.2    De Santis, M.3
  • 22
    • 0032977927 scopus 로고    scopus 로고
    • Cyclosporine treatment of glomerular diseases
    • Klein M, Radhakrishnan J, Appel G. Cyclosporine treatment of glomerular diseases. Annu Rev Med 1999; 50: 1.
    • (1999) Annu Rev Med , vol.50 , pp. 1
    • Klein, M.1    Radhakrishnan, J.2    Appel, G.3
  • 23
    • 27544481941 scopus 로고    scopus 로고
    • A function for interleukin 2 in Foxp3-expressing regulatory T cells
    • Fontenot JD, Rasmussen JP, Gavin MA, Rudensky AY. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat Immunol 2005; 6(11): 1142.
    • (2005) Nat Immunol , vol.6 , Issue.11 , pp. 1142
    • Fontenot, J.D.1    Rasmussen, J.P.2    Gavin, M.A.3    Rudensky, A.Y.4
  • 24
    • 27544446622 scopus 로고    scopus 로고
    • Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling
    • D'Cruz LM, Klein L. Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling. Nat Immunol 2005; 6(11): 1152.
    • (2005) Nat Immunol , vol.6 , Issue.11 , pp. 1152
    • D'Cruz, L.M.1    Klein, L.2
  • 25
    • 0027369395 scopus 로고
    • Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
    • Sadlack B, Merz H, Schorle H, et al. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell 1993; 75(2): 253.
    • (1993) Cell , vol.75 , Issue.2 , pp. 253
    • Sadlack, B.1    Merz, H.2    Schorle, H.3
  • 26
    • 0031568531 scopus 로고    scopus 로고
    • Immune restoration by fetal pig thymus grafts in T cell-depleted, thymectomized mice
    • Zhao Y, Fishman JA, Sergio JJ, et al. Immune restoration by fetal pig thymus grafts in T cell-depleted, thymectomized mice. J Immunol 1997; 158(4): 1641.
    • (1997) J Immunol , vol.158 , Issue.4 , pp. 1641
    • Zhao, Y.1    Fishman, J.A.2    Sergio, J.J.3
  • 27
    • 33645273175 scopus 로고    scopus 로고
    • Altered allogeneic immune responses in middle-aged mice
    • Sun Y, Li H, Langnas AN, Zhao Y. Altered allogeneic immune responses in middle-aged mice. Cell Mol Immunol 2004; 1(6): 440.
    • (2004) Cell Mol Immunol , vol.1 , Issue.6 , pp. 440
    • Sun, Y.1    Li, H.2    Langnas, A.N.3    Zhao, Y.4
  • 28
    • 33646013906 scopus 로고    scopus 로고
    • Induction of regulatory T cells from mature T cells by allogeneic thymic epithelial cells in vitro
    • Sun Y, Ge BS, Kasai M, et al. Induction of regulatory T cells from mature T cells by allogeneic thymic epithelial cells in vitro. Transpl Int 2006; 19(5): 404.
    • (2006) Transpl Int , vol.19 , Issue.5 , pp. 404
    • Sun, Y.1    Ge, B.S.2    Kasai, M.3
  • 29
    • 13944270218 scopus 로고    scopus 로고
    • CD4+CD25high regulatory T cells in human autoimmune diabetes
    • Putnam AL, Vendrame F, Dotta F, Gottlieb PA. CD4+CD25high regulatory T cells in human autoimmune diabetes. J Autoimmun 2005; 24(1): 55.
    • (2005) J Autoimmun , vol.24 , Issue.1 , pp. 55
    • Putnam, A.L.1    Vendrame, F.2    Dotta, F.3    Gottlieb, P.A.4
  • 30
    • 0024803090 scopus 로고
    • Cyclosporine A prevents the generation of single positive (Lyt2+ L3T4-, Lyt2- L3T4+) mature T cells, but not single positive (Lyt2+ T3-) Immature thymocytes, in newborn mice
    • Heeg K, Bendigs S, Wagner H. Cyclosporine A prevents the generation of single positive (Lyt2+ L3T4-, Lyt2- L3T4+) mature T cells, but not single positive (Lyt2+ T3-) Immature thymocytes, in newborn mice. Scand J Immunol 1989; 30(6): 703.
    • (1989) Scand J Immunol , vol.30 , Issue.6 , pp. 703
    • Heeg, K.1    Bendigs, S.2    Wagner, H.3
  • 31
    • 0028024022 scopus 로고
    • Thymocytes bearing high-density T cell receptor and CD2 are selectively eliminated in cyclosporine-induced thymic atrophy
    • Viciana AL, Ruiz P. Thymocytes bearing high-density T cell receptor and CD2 are selectively eliminated in cyclosporine-induced thymic atrophy. Transpl Immunol 1994; 2(3): 257.
    • (1994) Transpl Immunol , vol.2 , Issue.3 , pp. 257
    • Viciana, A.L.1    Ruiz, P.2
  • 32
    • 22244462396 scopus 로고    scopus 로고
    • Regulatory T cells in immunologic selftolerance and autoimmune disease
    • Sakaguchi S, Sakaguchi N. Regulatory T cells in immunologic selftolerance and autoimmune disease. Int Rev Immunol 2005; 24 (3-4): 211.
    • (2005) Int Rev Immunol , vol.24 , Issue.3-4 , pp. 211
    • Sakaguchi, S.1    Sakaguchi, N.2
  • 33
    • 0036857530 scopus 로고    scopus 로고
    • The role of suppressor T cells in regulation of immune responses
    • McHugh RS, Shevach EM. The role of suppressor T cells in regulation of immune responses. J Allergy Clin Immunol 2002; 110(5): 693.
    • (2002) J Allergy Clin Immunol , vol.110 , Issue.5 , pp. 693
    • McHugh, R.S.1    Shevach, E.M.2
  • 34
    • 6344279933 scopus 로고    scopus 로고
    • Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells
    • Stephens GL, McHugh RS, Whitters MJ, et al. Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells. J Immunol 2004; 173(8): 5008.
    • (2004) J Immunol , vol.173 , Issue.8 , pp. 5008
    • Stephens, G.L.1    McHugh, R.S.2    Whitters, M.J.3
  • 35
    • 0242407713 scopus 로고    scopus 로고
    • Control of immune homeostasis by naturally arising regulatory CD4+ T cells
    • Gavin M, Rudensky A. Control of immune homeostasis by naturally arising regulatory CD4+ T cells. Curr Opin Immunol 2003; 15(6): 690.
    • (2003) Curr Opin Immunol , vol.15 , Issue.6 , pp. 690
    • Gavin, M.1    Rudensky, A.2
  • 36
    • 17844364002 scopus 로고    scopus 로고
    • A role for CD103 in the retention of CD4+CD25+ Treg and control of Leishmania major infection
    • Suffia I, Reckling SK, Salay G, Belkaid Y. A role for CD103 in the retention of CD4+CD25+ Treg and control of Leishmania major infection. J Immunol 2005; 174(9): 5444.
    • (2005) J Immunol , vol.174 , Issue.9 , pp. 5444
    • Suffia, I.1    Reckling, S.K.2    Salay, G.3    Belkaid, Y.4
  • 37
    • 0037974772 scopus 로고    scopus 로고
    • A dual altered peptide ligand downregulates myasthenogenic T cell responses by up-regulating CD25- and CTLA-4-expressing CD4+ T cells
    • Paas-Rozner M, Sela M, Mozes E. A dual altered peptide ligand downregulates myasthenogenic T cell responses by up-regulating CD25- and CTLA-4-expressing CD4+ T cells. Proc Natl Acad Sci USA 2003; 100(11): 6676.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.11 , pp. 6676
    • Paas-Rozner, M.1    Sela, M.2    Mozes, E.3
  • 38
    • 33845698625 scopus 로고    scopus 로고
    • The phenotypic characterization of naturally occurring regulatory CD4+CD25+ T cells
    • Yi H, Zhen Y, Jiang L, et al. The phenotypic characterization of naturally occurring regulatory CD4+CD25+ T cells. Cell Mol Immunol 2006; 3(3): 189.
    • (2006) Cell Mol Immunol , vol.3 , Issue.3 , pp. 189
    • Yi, H.1    Zhen, Y.2    Jiang, L.3
  • 39
    • 14944346738 scopus 로고    scopus 로고
    • Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD
    • Ermann J, Hoffmann P, Edinger M, et al. Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD. Blood 2005; 105(5): 2220.
    • (2005) Blood , vol.105 , Issue.5 , pp. 2220
    • Ermann, J.1    Hoffmann, P.2    Edinger, M.3
  • 40
    • 0029956024 scopus 로고    scopus 로고
    • A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells
    • Powrie F, Carlino J, Leach MW, et al. A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells. J Exp Med 1996; 183(6): 2669.
    • (1996) J Exp Med , vol.183 , Issue.6 , pp. 2669
    • Powrie, F.1    Carlino, J.2    Leach, M.W.3
  • 41
    • 0031739410 scopus 로고    scopus 로고
    • CD38+ CD45RB(low) CD4+ T cells: A population of T cells with immune regulatory activities in vitro
    • Read S, Mauze S, Asseman C, et al. CD38+ CD45RB(low) CD4+ T cells: a population of T cells with immune regulatory activities in vitro. Eur J Immunol 1998; 28(11): 3435.
    • (1998) Eur J Immunol , vol.28 , Issue.11 , pp. 3435
    • Read, S.1    Mauze, S.2    Asseman, C.3
  • 42
    • 0029659049 scopus 로고    scopus 로고
    • Evidence for a thymus-dependent form of tolerance that is not based on elimination or anergy of reactive T cells
    • Le Douarin N, Corbel C, Bandeira A, et al. Evidence for a thymus-dependent form of tolerance that is not based on elimination or anergy of reactive T cells. Immunol Rev 1996; 149: 35.
    • (1996) Immunol Rev , vol.149 , pp. 35
    • Le Douarin, N.1    Corbel, C.2    Bandeira, A.3
  • 43
    • 0029806588 scopus 로고    scopus 로고
    • Inactivation of T cell receptor peptide-specific CD4 regulatory T cells induces chronic experimental autoimmune encephalomyelitis (EAE)
    • Kumar V, Stellrecht K, Sercarz E. Inactivation of T cell receptor peptide-specific CD4 regulatory T cells induces chronic experimental autoimmune encephalomyelitis (EAE). J Exp Med 1996; 184(5): 1609.
    • (1996) J Exp Med , vol.184 , Issue.5 , pp. 1609
    • Kumar, V.1    Stellrecht, K.2    Sercarz, E.3
  • 44
    • 0038046327 scopus 로고    scopus 로고
    • Despite efficient intrathymic negative selection of host-reactive T cells, autoimmune disease may develop in porcine thymus-grafted athymic mice: Evidence for failure of regulatory mechanisms suppressing autoimmunity
    • Zhao Y, Rodriguez-Barbosa JI, Shimizu A, et al. Despite efficient intrathymic negative selection of host-reactive T cells, autoimmune disease may develop in porcine thymus-grafted athymic mice: evidence for failure of regulatory mechanisms suppressing autoimmunity. Transplantation 2003; 75(11): 1832.
    • (2003) Transplantation , vol.75 , Issue.11 , pp. 1832
    • Zhao, Y.1    Rodriguez-Barbosa, J.I.2    Shimizu, A.3
  • 45
    • 7044224867 scopus 로고    scopus 로고
    • Regulatory CD4+ T cells and the control of autoimmune disease
    • Wraith DC, Nicolson KS, Whitley NT. Regulatory CD4+ T cells and the control of autoimmune disease. Curr Opin Immunol 2004; 16(6): 695.
    • (2004) Curr Opin Immunol , vol.16 , Issue.6 , pp. 695
    • Wraith, D.C.1    Nicolson, K.S.2    Whitley, N.T.3
  • 46
    • 29144516273 scopus 로고    scopus 로고
    • Global natural regulatory T cell depletion in active systemic lupus erythematosus
    • Miyara M, Amoura Z, Parizot C, et al. Global natural regulatory T cell depletion in active systemic lupus erythematosus. J Immunol 2005; 175(12): 8392.
    • (2005) J Immunol , vol.175 , Issue.12 , pp. 8392
    • Miyara, M.1    Amoura, Z.2    Parizot, C.3
  • 47
    • 0038666539 scopus 로고    scopus 로고
    • CD25+ cell depletion hastens the onset of severe disease in collagen-induced arthritis
    • Morgan ME, Sutmuller RP, Witteveen HJ, et al. CD25+ cell depletion hastens the onset of severe disease in collagen-induced arthritis. Arthritis Rheum 2003; 48(5): 1452.
    • (2003) Arthritis Rheum , vol.48 , Issue.5 , pp. 1452
    • Morgan, M.E.1    Sutmuller, R.P.2    Witteveen, H.J.3
  • 48
    • 18244383057 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells control induction of autoimmune hemolytic anemia
    • Mqadmi A, Zheng X, Yazdanbakhsh K. CD4+CD25+ regulatory T cells control induction of autoimmune hemolytic anemia. Blood 2005; 105(9): 3746.
    • (2005) Blood , vol.105 , Issue.9 , pp. 3746
    • Mqadmi, A.1    Zheng, X.2    Yazdanbakhsh, K.3
  • 49
    • 0022970843 scopus 로고
    • Cyclosporine-induced autoimmunity. Conditions for expressing disease, requirement for intact thymus, and potency estimates of autoimmune lymphocytes in drug-treated rats
    • Sorokin R, Kimura H, Schroder K, et al. Cyclosporine-induced autoimmunity. Conditions for expressing disease, requirement for intact thymus, and potency estimates of autoimmune lymphocytes in drug-treated rats. J Exp Med 1986; 164(5): 1615.
    • (1986) J Exp Med , vol.164 , Issue.5 , pp. 1615
    • Sorokin, R.1    Kimura, H.2    Schroder, K.3
  • 50
    • 0027320585 scopus 로고
    • Post-thymectomy organ-specific autoimmunity: Enhancement by cyclosporine A and inhibition by IL-2
    • Classen JB, Shevach EM. Post-thymectomy organ-specific autoimmunity: enhancement by cyclosporine A and inhibition by IL-2. Autoimmunity 1993; 15(1): 55.
    • (1993) Autoimmunity , vol.15 , Issue.1 , pp. 55
    • Classen, J.B.1    Shevach, E.M.2
  • 51
    • 0027331510 scopus 로고
    • Cyclosporine-induced syngeneic graft-vs-host disease: Prevention of autoaggression by treatment with monoclonal antibodies to T lymphocyte cell surface determinants and to MHC class II antigens
    • Hess AD, Horwitz LR, Laulis MK, Fuchs E. Cyclosporine-induced syngeneic graft-vs-host disease: prevention of autoaggression by treatment with monoclonal antibodies to T lymphocyte cell surface determinants and to MHC class II antigens. Clin Immunol Immunopathol 1993; 69(3): 341.
    • (1993) Clin Immunol Immunopathol , vol.69 , Issue.3 , pp. 341
    • Hess, A.D.1    Horwitz, L.R.2    Laulis, M.K.3    Fuchs, E.4
  • 52
    • 0026011912 scopus 로고
    • Loss of medullary dendritic cells in the thymus after cyclosporine and irradiation
    • Beschorner WE, Armas OA. Loss of medullary dendritic cells in the thymus after cyclosporine and irradiation. Cell Immunol 1991; 132(2): 505.
    • (1991) Cell Immunol , vol.132 , Issue.2 , pp. 505
    • Beschorner, W.E.1    Armas, O.A.2
  • 54
    • 0025821289 scopus 로고
    • Cyclosporine-induced autoimmunity and immune hyperreactivity
    • Prud'homme GJ, Parfrey NA, Vanier LE. Cyclosporine-induced autoimmunity and immune hyperreactivity. Autoimmunity 1991; 9(4): 345.
    • (1991) Autoimmunity , vol.9 , Issue.4 , pp. 345
    • Prud'homme, G.J.1    Parfrey, N.A.2    Vanier, L.E.3
  • 55
    • 0029797189 scopus 로고    scopus 로고
    • The mechanism of action of cyclosporin A and FK506
    • Ho S, Clipstone N, Timmermann L, et al. The mechanism of action of cyclosporin A and FK506. Clin Immunol Immunopathol 1996; 80 (3 Pt 2): S40.
    • (1996) Clin Immunol Immunopathol , vol.80 , Issue.3 PART 2
    • Ho, S.1    Clipstone, N.2    Timmermann, L.3
  • 56
    • 11144281814 scopus 로고    scopus 로고
    • Cyclosporin A produces distal renal tubular acidosis by blocking peptidyl prolyl cis-trans isomerase activity of cyclophilin
    • Watanabe S, Tsuruoka S, Vijayakumar S, et al. Cyclosporin A produces distal renal tubular acidosis by blocking peptidyl prolyl cis-trans isomerase activity of cyclophilin. Am J Physiol Renal Physiol 2005; 288(1): F40.
    • (2005) Am J Physiol Renal Physiol , vol.288 , Issue.1
    • Watanabe, S.1    Tsuruoka, S.2    Vijayakumar, S.3
  • 57
    • 0027960971 scopus 로고
    • Molecular analysis of the interaction of calcineurin with drug-immunophilin complexes
    • Clipstone NA, Fiorentino DF, Crabtree GR. Molecular analysis of the interaction of calcineurin with drug-immunophilin complexes. J Biol Chem 1994; 269(42): 26431.
    • (1994) J Biol Chem , vol.269 , Issue.42 , pp. 26431
    • Clipstone, N.A.1    Fiorentino, D.F.2    Crabtree, G.R.3
  • 58
    • 0027323876 scopus 로고
    • Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin a and FK506: Roles of calcineurin binding and cellular location
    • Bram RJ, Hung DT, Martin PK, et al. Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location. Mol Cell Biol 1993; 13(8): 4760.
    • (1993) Mol Cell Biol , vol.13 , Issue.8 , pp. 4760
    • Bram, R.J.1    Hung, D.T.2    Martin, P.K.3
  • 59
    • 0026643141 scopus 로고
    • Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation
    • Clipstone NA, Crabtree GR. Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation. Nature 1992; 357(6380): 695.
    • (1992) Nature , vol.357 , Issue.6380 , pp. 695
    • Clipstone, N.A.1    Crabtree, G.R.2
  • 60
    • 0024318981 scopus 로고
    • Advances in cyclosporine pharmacology, measurement, and therapeutic monitoring
    • Shaw LM. Advances in cyclosporine pharmacology, measurement, and therapeutic monitoring. Clin Chem 1989; 35(7): 1299.
    • (1989) Clin Chem , vol.35 , Issue.7 , pp. 1299
    • Shaw, L.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.