메뉴 건너뛰기




Volumn 184, Issue 5, 1996, Pages 1609-1617

Inactivation of T cell receptor peptide-specific CD4 regulatory T cells induces chronic experimental autoimmune encephalomyelitis (EAE)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; MYELIN BASIC PROTEIN; T LYMPHOCYTE RECEPTOR;

EID: 0029806588     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.184.5.1609     Document Type: Article
Times cited : (109)

References (34)
  • 1
    • 0023722525 scopus 로고
    • The T cell repertoire for antigen and MHC
    • Marrack, P., and J. Kappler. 1988. The T cell repertoire for antigen and MHC. Immunol. Today. 9:308-315.
    • (1988) Immunol. Today , vol.9 , pp. 308-315
    • Marrack, P.1    Kappler, J.2
  • 3
    • 0028017808 scopus 로고
    • A differential-avidity model for T cell selection
    • Ashton-Rickardt, A., and S. Tonegawa. 1994. A differential-avidity model for T cell selection. Immunol. Today. 15:362-366.
    • (1994) Immunol. Today , vol.15 , pp. 362-366
    • Ashton-Rickardt, A.1    Tonegawa, S.2
  • 4
    • 0027092667 scopus 로고
    • T-cell subsets in autoimmunity
    • Mason, D., and D. Fowell. 1992. T-cell subsets in autoimmunity. Curr. Opin. Immunol. 4:728-732.
    • (1992) Curr. Opin. Immunol. , vol.4 , pp. 728-732
    • Mason, D.1    Fowell, D.2
  • 5
    • 0027497193 scopus 로고
    • T-cell subsets in autoimmunity
    • O'Garra, A., and K. Murphy. 1993. T-cell subsets in autoimmunity. Curr. Opin. Immunol. 5:880-886.
    • (1993) Curr. Opin. Immunol. , vol.5 , pp. 880-886
    • O'Garra, A.1    Murphy, K.2
  • 7
    • 0025273805 scopus 로고
    • Autoimmune thyroiditis induced in mice depleted of particular T cell subset. III. Analysis of regulatory cells suppressing the induction of thyroiditis
    • Sugihara, S., S. Maruo, T. Tsujimura, O. Tarutani, Y. Kohno, T. Hamaoka, and H. Fujiwara. 1990. Autoimmune thyroiditis induced in mice depleted of particular T cell subset. III. Analysis of regulatory cells suppressing the induction of thyroiditis. Int. Immunol. 2:343-351.
    • (1990) Int. Immunol. , vol.2 , pp. 343-351
    • Sugihara, S.1    Maruo, S.2    Tsujimura, T.3    Tarutani, O.4    Kohno, Y.5    Hamaoka, T.6    Fujiwara, H.7
  • 10
  • 11
    • 0023751365 scopus 로고
    • Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy
    • Urban, J.L., V. Kumar, D.H. Kono, C. Gomez, S.J. Horvath, J. Clayton, D.G. Ando, E.E. Sercarz, and L. Hood. 1988. Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy. Cell. 54:577-592.
    • (1988) Cell , vol.54 , pp. 577-592
    • Urban, J.L.1    Kumar, V.2    Kono, D.H.3    Gomez, C.4    Horvath, S.J.5    Clayton, J.6    Ando, D.G.7    Sercarz, E.E.8    Hood, L.9
  • 12
    • 0024405828 scopus 로고
    • T cell receptor repertoire and autoimmune diseases
    • Kumar, V., D. Kono, J. Urban, and L. Hood. 1988. T cell receptor repertoire and autoimmune diseases Annu. Rev. Immnol. 7:657-682.
    • (1988) Annu. Rev. Immnol. , vol.7 , pp. 657-682
    • Kumar, V.1    Kono, D.2    Urban, J.3    Hood, L.4
  • 13
    • 45149146393 scopus 로고
    • The V-region hypothesis: Evidence from autoimmune encephalomyelitis
    • Heber-Katz, E., and H. Acha-Orbea. 1989. The V-region hypothesis: evidence from autoimmune encephalomyelitis. Immunol. Today. 10:164-166.
    • (1989) Immunol. Today , vol.10 , pp. 164-166
    • Heber-Katz, E.1    Acha-Orbea, H.2
  • 14
    • 0019487117 scopus 로고
    • Vaccination against autoimmune encephalomyelitis using attenuated cells of a T lymphocyte line reactive against myelin basic protein
    • Ben-Nun, A., H. Wekerle, and I.R. Cohen. 1981. Vaccination against autoimmune encephalomyelitis using attenuated cells of a T lymphocyte line reactive against myelin basic protein. Nature (Lond.). 292:60-61.
    • (1981) Nature (Lond.) , vol.292 , pp. 60-61
    • Ben-Nun, A.1    Wekerle, H.2    Cohen, I.R.3
  • 15
    • 0024425273 scopus 로고
    • Immunization with a synthetic T-cell receptor V-region peptide protects against experimental autoimmune encephalomyelitis
    • Vandenbark, A.A., G. Hashim, and H. Offner. 1989. Immunization with a synthetic T-cell receptor V-region peptide protects against experimental autoimmune encephalomyelitis. Nature (Lond.). 341:541-544.
    • (1989) Nature (Lond.) , vol.341 , pp. 541-544
    • Vandenbark, A.A.1    Hashim, G.2    Offner, H.3
  • 17
    • 0028887507 scopus 로고
    • The dominant self-TCR peptide from the framework III region of the β-chain controls murine EAE
    • Kumar, V., R. Tabibiazar, H.M. Geysen, and E. Sercarz. 1995. The dominant self-TCR peptide from the framework III region of the β-chain controls murine EAE. J. Immunol. 154:1941-1950.
    • (1995) J. Immunol. , vol.154 , pp. 1941-1950
    • Kumar, V.1    Tabibiazar, R.2    Geysen, H.M.3    Sercarz, E.4
  • 18
    • 0027249369 scopus 로고
    • + T cells in recovery from antigen-induced autoimmune disease
    • + T cells in recovery from antigen-induced autoimmune disease. J. Exp. Med. 178: 909-916.
    • (1993) J. Exp. Med. , vol.178 , pp. 909-916
    • Kumar, V.1    Sercarz, E.2
  • 20
    • 0025150810 scopus 로고
    • Class I and class II MHC gene products differentially affect the fate of Vβ5 bearing thymocytes
    • Bill, J., O. Kanagawa, and J. Linten. 1990. Class I and class II MHC gene products differentially affect the fate of Vβ5 bearing thymocytes. J. Mol. Cell. Immunol. 4:269-279.
    • (1990) J. Mol. Cell. Immunol. , vol.4 , pp. 269-279
    • Bill, J.1    Kanagawa, O.2    Linten, J.3
  • 21
    • 0023732130 scopus 로고
    • The T cell repertoire is heavily influenced by tolerance to polymorphic self antigens
    • Pullen, A., P. Marrack, and J.W. Kappler. 1988. The T cell repertoire is heavily influenced by tolerance to polymorphic self antigens. Nature (Lond.). 355:796-801.
    • (1988) Nature (Lond.) , vol.355 , pp. 796-801
    • Pullen, A.1    Marrack, P.2    Kappler, J.W.3
  • 23
    • 0024428816 scopus 로고
    • How some T cells escape tolerance induction
    • Gammon, G., and E. Sercarz. 1989. How some T cells escape tolerance induction. Nature (Lond.). 342:183-185.
    • (1989) Nature (Lond.) , vol.342 , pp. 183-185
    • Gammon, G.1    Sercarz, E.2
  • 24
    • 0026664422 scopus 로고
    • Determinant spreading in autoimmunity: Cryptic T-cell determinants of myelin basic protein become immunogenic after immunization with a dominant peptide of the molecule
    • Lehmann, P.V., T. Forsthuber, A. Miller, and E.E. Sercarz. 1992. Determinant spreading in autoimmunity: cryptic T-cell determinants of myelin basic protein become immunogenic after immunization with a dominant peptide of the molecule. Nature (Lond.). 358:155-157.
    • (1992) Nature (Lond.) , vol.358 , pp. 155-157
    • Lehmann, P.V.1    Forsthuber, T.2    Miller, A.3    Sercarz, E.E.4
  • 25
    • 0028285061 scopus 로고
    • Holes in the T cell repertoire to MBP owing to the absence of the Dβ2-Jβ2 gene cluster: Implications for T cell receptor recognition and autoimmunity
    • Kumar, V., and E. Sercarz. 1994. Holes in the T cell repertoire to MBP owing to the absence of the Dβ2-Jβ2 gene cluster: implications for T cell receptor recognition and autoimmunity. J. Exp. Med. 179:1637-1643.
    • (1994) J. Exp. Med. , vol.179 , pp. 1637-1643
    • Kumar, V.1    Sercarz, E.2
  • 26
    • 0027505094 scopus 로고
    • Degenerate recognition of a dissimilar antigenic peptide by MBP-reactive T cells: Implications for thymic education and autoimmunity
    • Bhardwaj, V., V. Kumar, H.M. Geysen, and E. Sercarz. 1993. Degenerate recognition of a dissimilar antigenic peptide by MBP-reactive T cells: implications for thymic education and autoimmunity. J. Immunol. 151:5000-5010.
    • (1993) J. Immunol. , vol.151 , pp. 5000-5010
    • Bhardwaj, V.1    Kumar, V.2    Geysen, H.M.3    Sercarz, E.4
  • 27
    • 0030002897 scopus 로고    scopus 로고
    • Neonatal peptide exposure can prime T cells, and upon subsequent immunization induce their immune deviation: Implications for antibody vs. T cell-mediated autoimmunity
    • Singh, R.R., B.H. Hahn, and E.E. Sercarz. 1996. Neonatal peptide exposure can prime T cells, and upon subsequent immunization induce their immune deviation: implications for antibody vs. T cell-mediated autoimmunity. J. Exp. Med. 183:1613-1622.
    • (1996) J. Exp. Med. , vol.183 , pp. 1613-1622
    • Singh, R.R.1    Hahn, B.H.2    Sercarz, E.E.3
  • 28
    • 0028831143 scopus 로고
    • Increased seventy of experimental autoimmune encephalomyelitis in rats tolerized as adults but not neonatally to a protective TCR Vβ8 CDR2 idiotope
    • Offner, H., M.K.H. Malotky, L. Pope, M. Vainiene, B. Celnik, S.D. Miller, and A.A. Vandenbark. 1995. Increased seventy of experimental autoimmune encephalomyelitis in rats tolerized as adults but not neonatally to a protective TCR Vβ8 CDR2 idiotope. J Immunol. 154:928-935.
    • (1995) J Immunol. , vol.154 , pp. 928-935
    • Offner, H.1    Malotky, M.K.H.2    Pope, L.3    Vainiene, M.4    Celnik, B.5    Miller, S.D.6    Vandenbark, A.A.7
  • 29
    • 0029000750 scopus 로고
    • Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelids
    • McRae, B.L., C.L. Vanderlugt, M.C. Dal Canto, and S.D. Miller. 1995. Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelids. J. Exp. Med. 182:75-85.
    • (1995) J. Exp. Med. , vol.182 , pp. 75-85
    • McRae, B.L.1    Vanderlugt, C.L.2    Dal Canto, M.C.3    Miller, S.D.4
  • 30
    • 0027318299 scopus 로고
    • Diverse T cell receptor Vβ gene usage in the central nervous system in experimental allergic encephalomyelitis
    • Bell, R.B., J.W. Lindsey, R.A. Sobel, S. Hodgkinson, and L. Steinman. 1993. Diverse T cell receptor Vβ gene usage in the central nervous system in experimental allergic encephalomyelitis. J. Immunol. 150:4085-4092.
    • (1993) J. Immunol. , vol.150 , pp. 4085-4092
    • Bell, R.B.1    Lindsey, J.W.2    Sobel, R.A.3    Hodgkinson, S.4    Steinman, L.5
  • 31
    • 0026378637 scopus 로고
    • The problem of presentation of T cell receptor peptides by activated T cell
    • Jiang, H., E. Sercarz, D. Nitecki, and B. Pernis. 1991. The problem of presentation of T cell receptor peptides by activated T cell:. Ann. NY Acad. Sci. 636:28-32.
    • (1991) Ann. NY Acad. Sci. , vol.636 , pp. 28-32
    • Jiang, H.1    Sercarz, E.2    Nitecki, D.3    Pernis, B.4
  • 33
    • 0026647293 scopus 로고
    • + T cells in experimental allergic encephalomyelitis
    • + T cells in experimental allergic encephalomyelitis. Science (Wash. DC). 256:1213-1215.
    • (1992) Science (Wash. DC) , vol.256 , pp. 1213-1215
    • Jiang, H.1    Zhang, S.2    Pernis, B.3
  • 34
    • 0027345986 scopus 로고
    • T cell regulatory circuitry: Antigen-specific and TCR-idiopeptide-specific T cell interactions in EAE
    • Kumar, V., and E. Sercarz. 1992. T cell regulatory circuitry: antigen-specific and TCR-idiopeptide-specific T cell interactions in EAE. Int. Rev. Immunol. 9:287-297.
    • (1992) Int. Rev. Immunol. , vol.9 , pp. 287-297
    • Kumar, V.1    Sercarz, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.