Preferential block of inactivation-deficient Na+ currents by capsaicin reveals a non-TRPV1 receptor within the Na+ channel

Pain

Volumn 127, Issue 1-2, 2007, Pages 73-83

  Wang, Sho Ya ^a   Mitchell, Jane ^b   Wang, Ging Kuo ^b  

^a STATE UNIVERSITY OF NEW YORK   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Analgesia; Capsaicin; Open channel block; Use dependent block; Voltage gated sodium channel

Indexed keywords

BATRACHOTOXIN; CAPSAICIN; MUTANT PROTEIN; SODIUM CHANNEL; VANILLOID RECEPTOR;

ANIMAL CELL; ARTICLE; CELL STRAIN GH3; CELL STRAIN HEK293; DISSOCIATION CONSTANT; DRUG EFFECT; HUMAN; HUMAN CELL; IC 50; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; SITE DIRECTED MUTAGENESIS; SKELETAL MUSCLE; SODIUM CURRENT; WILD TYPE;

ANIMALS; CAPSAICIN; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; ION CHANNEL GATING; KIDNEY; MEMBRANE POTENTIALS; MUSCLE FIBERS; RATS; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; TRPV CATION CHANNELS;

EID: 33845609215     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2006.08.002     Document Type: Article

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