In vivo pharmacology of SDZ 249-665, a novel, non-pungent capsaicin analogue

Pain

Volumn 89, Issue 1, 2000, Pages 65-74

  Urban, Laszlo ^a   Campbell, Elizabeth A ^a   Panesar, Moh ^a   Patel, Sadhana ^a   Chaudhry, Naureen ^a   Kane, Steven ^a   Buchheit, Karl Heinz ^a   Sandells, Barrie ^a   James, Iain F ^a  

^a Novatis Inst for Medical Sciences   (United Kingdom)

Author keywords

Analgesia; Capsaicin; Hyperalgesia; Nociception; Therapeutic window

Indexed keywords

ACETIC ACID; CAPSAICIN; CAPSAICIN DERIVATIVE; CAPSAZEPINE; CARRAGEENAN; RESINIFERATOXIN; SDZ 249 665; TURPENTINE; UNCLASSIFIED DRUG; VANILLOID RECEPTOR;

ANALGESIA; ANALGESIC ACTIVITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; BRONCHOSPASM; CALCIUM TRANSPORT; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG RECEPTOR BINDING; DRUG TOLERANCE; EXCITATION; EYE IRRITATION; FEMALE; GUINEA PIG; HYPERALGESIA; INFLAMMATION; MALE; MOUSE; MUSCLE SPINDLE AFFERENT NERVE; NOCICEPTIVE STIMULATION; NONHUMAN; NOSE IRRITATION; PRIORITY JOURNAL; RAT; SPINAL GANGLION; STRUCTURE ACTIVITY RELATION; TAIL FLICK TEST; THERMAL STIMULATION; WRITHING TEST;

ANALGESICS; ANIMALS; BEHAVIOR, ANIMAL; BLINKING; BLOOD PRESSURE; BRONCHOCONSTRICTION; CAPSAICIN; CARRAGEENAN; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; EYE; FEMALE; GANGLIA, SPINAL; GUINEA PIGS; HINDLIMB; HYPERALGESIA; IRRITANTS; MALE; MICE; MICE, INBRED STRAINS; NOCICEPTORS; NOSE; ODORS; PAIN; PAIN MEASUREMENT; RATS; RATS, SPRAGUE-DAWLEY; TURPENTINE;

EID: 0034672692     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(00)00349-3     Document Type: Article

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