Capsaicin regulates voltage-dependent sodium channels by altering lipid bilayer elasticity

Molecular Pharmacology

Volumn 68, Issue 3, 2005, Pages 680-689

  Lundbaek J A ^a,b,d,e   Birn, P ^a   Tape, S E ^b   Toombes, G E S ^c   Sogaard R ^d   Koeppe II, Roger E ^f   Gruner, S M ^c   Hansen, A J ^a   Andersen, O S ^b  

^a NOVO NORDISK A S   (Denmark)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c Cornell University   (United States)

^d Sct Hans Hospital   (Denmark)

^e UNIVERSITY OF COPENHAGEN   (Denmark)

^f UNIVERSITY OF ARKANSAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOPHILE; CAPSAICIN; CAPSAZEPINE; GRAMICIDIN A; MEMBRANE PROTEIN; REGULATOR PROTEIN; TRITON X 100; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL CELL; ARTICLE; CELL MEMBRANE CONDUCTANCE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ELASTICITY; EMBEDDING; HUMAN; HUMAN CELL; HYPERPOLARIZATION; LIPID BILAYER; LIPID MONOLAYER; MEASUREMENT; MECHANOTRANSDUCTION; MEMBRANE STABILIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; RAT; REGULATORY MECHANISM; RIGIDITY;

CAPSAICIN; GRAMICIDIN; KINETICS; LIPID BILAYERS; PATCH-CLAMP TECHNIQUES; SCATTERING, RADIATION; SODIUM CHANNELS;

EID: 23944464223     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.105.013573     Document Type: Article

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